After_comments
ERM
2024-01-02
Last updated: 2024-01-02
Checks: 7 0
Knit directory: Cardiotoxicity/
This reproducible R Markdown analysis was created with workflowr (version 1.7.1). The Checks tab describes the reproducibility checks that were applied when the results were created. The Past versions tab lists the development history.
Great! Since the R Markdown file has been committed to the Git repository, you know the exact version of the code that produced these results.
Great job! The global environment was empty. Objects defined in the global environment can affect the analysis in your R Markdown file in unknown ways. For reproduciblity it’s best to always run the code in an empty environment.
The command set.seed(20230109) was run prior to running
the code in the R Markdown file. Setting a seed ensures that any results
that rely on randomness, e.g. subsampling or permutations, are
reproducible.
Great job! Recording the operating system, R version, and package versions is critical for reproducibility.
Nice! There were no cached chunks for this analysis, so you can be confident that you successfully produced the results during this run.
Great job! Using relative paths to the files within your workflowr project makes it easier to run your code on other machines.
Great! You are using Git for version control. Tracking code development and connecting the code version to the results is critical for reproducibility.
The results in this page were generated with repository version 4fb0cde. See the Past versions tab to see a history of the changes made to the R Markdown and HTML files.
Note that you need to be careful to ensure that all relevant files for
the analysis have been committed to Git prior to generating the results
(you can use wflow_publish or
wflow_git_commit). workflowr only checks the R Markdown
file, but you know if there are other scripts or data files that it
depends on. Below is the status of the Git repository when the results
were generated:
Ignored files:
Ignored: .RData
Ignored: .Rhistory
Ignored: .Rproj.user/
Ignored: analysis/figure/
Ignored: analysis/variance_values by gene.png
Ignored: data/41588_2018_171_MOESM3_ESMeQTL_ST2_for paper.csv
Ignored: data/Arr_GWAS.txt
Ignored: data/Arr_geneset.RDS
Ignored: data/BC_cell_lines.csv
Ignored: data/BurridgeDOXTOX.RDS
Ignored: data/CADGWASgene_table.csv
Ignored: data/CAD_geneset.RDS
Ignored: data/CALIMA_Data/
Ignored: data/CMD04_75DRCviability.csv
Ignored: data/CMD04_87DRCviability.csv
Ignored: data/CMD05_75DRCviability.csv
Ignored: data/CMD05_87DRCviability.csv
Ignored: data/Clamp_Summary.csv
Ignored: data/Cormotif_24_k1-5_raw.RDS
Ignored: data/Counts_RNA_ERMatthews.txt
Ignored: data/DAgostres24.RDS
Ignored: data/DAtable1.csv
Ignored: data/DDEMresp_list.csv
Ignored: data/DDE_reQTL.txt
Ignored: data/DDEresp_list.csv
Ignored: data/DEG-GO/
Ignored: data/DEG_cormotif.RDS
Ignored: data/DF_Plate_Peak.csv
Ignored: data/DRC48hoursdata.csv
Ignored: data/Da24counts.txt
Ignored: data/Dx24counts.txt
Ignored: data/Dx_reQTL_specific.txt
Ignored: data/EPIstorelist24.RDS
Ignored: data/Ep24counts.txt
Ignored: data/FC_necela.RDS
Ignored: data/FC_necela_names.RDS
Ignored: data/Full_LD_rep.csv
Ignored: data/GOIsig.csv
Ignored: data/GOplots.R
Ignored: data/GTEX_setsimple.csv
Ignored: data/GTEX_sig24.RDS
Ignored: data/GTEx_gene_list.csv
Ignored: data/HFGWASgene_table.csv
Ignored: data/HF_geneset.RDS
Ignored: data/Heart_Left_Ventricle.v8.egenes.txt
Ignored: data/Heatmap_mat.RDS
Ignored: data/Heatmap_sig.RDS
Ignored: data/Hf_GWAS.txt
Ignored: data/K_cluster
Ignored: data/K_cluster_kisthree.csv
Ignored: data/K_cluster_kistwo.csv
Ignored: data/Knowles_log2cpm_real.RDS
Ignored: data/Knowles_variation_data.RDS
Ignored: data/Knowles_variation_data_conc.RDS
Ignored: data/Knowlesvarlist.RDS
Ignored: data/LD50_05via.csv
Ignored: data/LDH48hoursdata.csv
Ignored: data/Mt24counts.txt
Ignored: data/NoRespDEG_final.csv
Ignored: data/RINsamplelist.txt
Ignored: data/RNA_seq_trial.RDS
Ignored: data/Schneider_GWAS.txt
Ignored: data/Seonane2019supp1.txt
Ignored: data/Sup_replicate_values.csv
Ignored: data/TMMnormed_x.RDS
Ignored: data/TOP2Bi-24hoursGO_analysis.csv
Ignored: data/TR24counts.txt
Ignored: data/TableS10.csv
Ignored: data/TableS11.csv
Ignored: data/TableS9.csv
Ignored: data/Top2_expression.RDS
Ignored: data/Top2biresp_cluster24h.csv
Ignored: data/Var_test_list.RDS
Ignored: data/Var_test_list24.RDS
Ignored: data/Var_test_list24alt.RDS
Ignored: data/Var_test_list3.RDS
Ignored: data/Vargenes.RDS
Ignored: data/Viabilitylistfull.csv
Ignored: data/allexpressedgenes.txt
Ignored: data/allfinal3hour.RDS
Ignored: data/allgenes.txt
Ignored: data/allmatrix.RDS
Ignored: data/allmymatrix.RDS
Ignored: data/annotation_data_frame.RDS
Ignored: data/averageviabilitytable.RDS
Ignored: data/averageviabilitytable.csv
Ignored: data/avgLD50.RDS
Ignored: data/avg_LD50.RDS
Ignored: data/avg_via_table.csv
Ignored: data/backGL.txt
Ignored: data/burr_genes.RDS
Ignored: data/calcium_data.RDS
Ignored: data/clamp_summary.RDS
Ignored: data/cormotif_3hk1-8.RDS
Ignored: data/cormotif_initalK5.RDS
Ignored: data/cormotif_initialK5.RDS
Ignored: data/cormotif_initialall.RDS
Ignored: data/cormotifprobs.csv
Ignored: data/counts24hours.RDS
Ignored: data/cpmcount.RDS
Ignored: data/cpmnorm_counts.csv
Ignored: data/crispr_genes.csv
Ignored: data/ctnnt_results.txt
Ignored: data/cvd_GWAS.txt
Ignored: data/dat_cpm.RDS
Ignored: data/data_outline.txt
Ignored: data/drug_noveh1.csv
Ignored: data/efit2.RDS
Ignored: data/efit2_final.RDS
Ignored: data/efit2results.RDS
Ignored: data/ensembl_backup.RDS
Ignored: data/ensgtotal.txt
Ignored: data/filcpm_counts.RDS
Ignored: data/filenameonly.txt
Ignored: data/filtered_cpm_counts.csv
Ignored: data/filtered_raw_counts.csv
Ignored: data/filtermatrix_x.RDS
Ignored: data/folder_05top/
Ignored: data/framefun24.RDS
Ignored: data/geneDoxonlyQTL.csv
Ignored: data/gene_corr_df.RDS
Ignored: data/gene_corr_frame.RDS
Ignored: data/gene_prob_tran3h.RDS
Ignored: data/gene_probabilityk5.RDS
Ignored: data/geneset_24.RDS
Ignored: data/gostresTop2bi_ER.RDS
Ignored: data/gostresTop2bi_LR
Ignored: data/gostresTop2bi_LR.RDS
Ignored: data/gostresTop2bi_TI.RDS
Ignored: data/gostrescoNR
Ignored: data/gtex/
Ignored: data/heartgenes.csv
Ignored: data/highly_var_genelist.RDS
Ignored: data/hsa_kegg_anno.RDS
Ignored: data/individualDRCfile.RDS
Ignored: data/individual_DRC48.RDS
Ignored: data/individual_LDH48.RDS
Ignored: data/indv_noveh1.csv
Ignored: data/kegglistDEG.RDS
Ignored: data/kegglistDEG24.RDS
Ignored: data/kegglistDEG3.RDS
Ignored: data/knowfig4.csv
Ignored: data/knowfig5.csv
Ignored: data/label_list.RDS
Ignored: data/ld50_table.csv
Ignored: data/mean_vardrug1.csv
Ignored: data/mean_varframe.csv
Ignored: data/mymatrix.RDS
Ignored: data/new_ld50avg.RDS
Ignored: data/nonresponse_cluster24h.csv
Ignored: data/norm_LDH.csv
Ignored: data/norm_counts.csv
Ignored: data/old_sets/
Ignored: data/organized_drugframe.csv
Ignored: data/pca_all_anno.csv
Ignored: data/plan2plot.png
Ignored: data/plot_intv_list.RDS
Ignored: data/plot_list_DRC.RDS
Ignored: data/qval24hr.RDS
Ignored: data/qval3hr.RDS
Ignored: data/qvalueEPItemp.RDS
Ignored: data/raw_counts.csv
Ignored: data/response_cluster24h.csv
Ignored: data/sampsettrz.RDS
Ignored: data/schneider_closest_output.RDS
Ignored: data/sigVDA24.txt
Ignored: data/sigVDA3.txt
Ignored: data/sigVDX24.txt
Ignored: data/sigVDX3.txt
Ignored: data/sigVEP24.txt
Ignored: data/sigVEP3.txt
Ignored: data/sigVMT24.txt
Ignored: data/sigVMT3.txt
Ignored: data/sigVTR24.txt
Ignored: data/sigVTR3.txt
Ignored: data/siglist.RDS
Ignored: data/siglist_final.RDS
Ignored: data/siglist_old.RDS
Ignored: data/slope_table.csv
Ignored: data/supp10_24hlist.RDS
Ignored: data/supp10_3hlist.RDS
Ignored: data/supp_normLDH48.RDS
Ignored: data/supp_pca_all_anno.RDS
Ignored: data/supp_viadata.csv
Ignored: data/table3a.omar
Ignored: data/test_run_sample_list.txt
Ignored: data/testlist.txt
Ignored: data/toplistall.RDS
Ignored: data/trtonly_24h_genes.RDS
Ignored: data/trtonly_3h_genes.RDS
Ignored: data/tvl24hour.txt
Ignored: data/tvl24hourw.txt
Ignored: data/venn_code.R
Ignored: data/viability.RDS
Untracked files:
Untracked: .RDataTmp
Untracked: .RDataTmp1
Untracked: .RDataTmp2
Untracked: .RDataTmp3
Untracked: 3hr all.pdf
Untracked: Code_files_list.csv
Untracked: Data_files_list.csv
Untracked: Doxorubicin_vehicle_3_24.csv
Untracked: Doxtoplist.csv
Untracked: EPIqvalue_analysis.Rmd
Untracked: Final.sup.pdf
Untracked: GWAS_list_of_interest.xlsx
Untracked: KEGGpathwaylist.R
Untracked: OmicNavigator_learn.R
Untracked: SNP_egenes_allfiles.RDS
Untracked: SigDoxtoplist.csv
Untracked: analysis/DRC_viability_check.Rmd
Untracked: analysis/New_code_dec-23.R
Untracked: analysis/cellcycle_kegg_genes.R
Untracked: analysis/ciFIT.R
Untracked: analysis/export_to_excel.R
Untracked: analysis/featureCountsPLAY.R
Untracked: cleanupfiles_script.R
Untracked: code/biomart_gene_names.R
Untracked: code/constantcode.R
Untracked: code/corMotifcustom.R
Untracked: code/cpm_boxplot.R
Untracked: code/extracting_ggplot_data.R
Untracked: code/movingfilesto_ppl.R
Untracked: code/pearson_extract_func.R
Untracked: code/pearson_tox_extract.R
Untracked: code/plot1C.fun.R
Untracked: code/spearman_extract_func.R
Untracked: code/venndiagramcolor_control.R
Untracked: cormotif_p.post.list_4.csv
Untracked: figS1024h.pdf
Untracked: final.pdf
Untracked: individual-legenddark2.png
Untracked: installed_old.rda
Untracked: listoftranscripts
Untracked: motif_ER.txt
Untracked: motif_LR.txt
Untracked: motif_NR.txt
Untracked: motif_TI.txt
Untracked: output/ABHD8_dif_values.RDS
Untracked: output/C3orf18_dif_values.RDS
Untracked: output/Cardiotox_dif_values.RDS
Untracked: output/DNR_DEGlist.csv
Untracked: output/DNRvenn.RDS
Untracked: output/DOX_DEGlist.csv
Untracked: output/DOX_de_goi.csv
Untracked: output/DOXvenn.RDS
Untracked: output/EEF1B2_dif_values.RDS
Untracked: output/EEIG1_dif_values.RDS
Untracked: output/EPI_DEGlist.csv
Untracked: output/EPIvenn.RDS
Untracked: output/ESGN_rds.RDS
Untracked: output/FC_necela.RDS
Untracked: output/FC_necela_names.RDS
Untracked: output/FRS2_dif_values.RDS
Untracked: output/Figures/
Untracked: output/GTEXv8_gene_median_tpm.RDS
Untracked: output/GTEXv8_gene_tpm_heart_left_ventricle.RDS
Untracked: output/HDDC2_dif_values.RDS
Untracked: output/HER2_gene.RDS
Untracked: output/KEGGcellcyclegenes.RDS
Untracked: output/Knowles_S13.csv
Untracked: output/Knowles_log2cpm.csv
Untracked: output/Knowles_supp13.csv
Untracked: output/MTX_DEGlist.csv
Untracked: output/MTXvenn.RDS
Untracked: output/PEX16_dif_values.RDS
Untracked: output/RASIP1_dif_values.RDS
Untracked: output/RMI1_dif_values.RDS
Untracked: output/RSID_QTL_list_full.txt
Untracked: output/SETA_analysis_reyes.RDS
Untracked: output/SGWAS_top50_order.csv
Untracked: output/SLC27A1_dif_values.RDS
Untracked: output/SLC28A3_dif_values.RDS
Untracked: output/SNP_egenes_allfiles.RDS
Untracked: output/SNP_list_ID.RDS
Untracked: output/SNP_list_full.txt
Untracked: output/SNP_supp.RDS
Untracked: output/TGFBR3L_dif_values.RDS
Untracked: output/TNS2_dif_values.RDS
Untracked: output/TOP_50SNPreffile.csv
Untracked: output/TRZ_DEGlist.csv
Untracked: output/TableS8.csv
Untracked: output/Volcanoplot_10
Untracked: output/Volcanoplot_10.RDS
Untracked: output/ZNF740_dif_values.RDS
Untracked: output/allfinal_sup10.RDS
Untracked: output/counts_v8_heart_left_ventricle_gct.RDS
Untracked: output/crisprfoldchange.RDS
Untracked: output/endocytosisgenes.csv
Untracked: output/expre7k.csv
Untracked: output/expressed_egenes_by_RSID.csv
Untracked: output/gene_corr_fig9.RDS
Untracked: output/genes.RDS
Untracked: output/legend_b.RDS
Untracked: output/motif_ERrep.RDS
Untracked: output/motif_LRrep.RDS
Untracked: output/motif_NRrep.RDS
Untracked: output/motif_TI_rep.RDS
Untracked: output/near_genes_SNP1.RDS
Untracked: output/necela_list_test.RDS
Untracked: output/necela_val_genes.RDS
Untracked: output/output-old/
Untracked: output/rank24genes.csv
Untracked: output/rank3genes.csv
Untracked: output/reneem@ls6.tacc.utexas.edu
Untracked: output/sequencinginformationforsupp.csv
Untracked: output/sequencinginformationforsupp.prn
Untracked: output/sigVDA24.txt
Untracked: output/sigVDA3.txt
Untracked: output/sigVDX24.txt
Untracked: output/sigVDX3.txt
Untracked: output/sigVEP24.txt
Untracked: output/sigVEP3.txt
Untracked: output/sigVMT24.txt
Untracked: output/sigVMT3.txt
Untracked: output/sigVTR24.txt
Untracked: output/sigVTR3.txt
Untracked: output/supplementary_motif_list_GO.RDS
Untracked: output/test_biomart_run.RDS
Untracked: output/toptablebydrug.RDS
Untracked: output/trop_knowles_fun.csv
Untracked: output/tvl24hour.txt
Untracked: output/x_counts.RDS
Untracked: reneebasecode.R
Unstaged changes:
Modified: analysis/DRC_analysis.Rmd
Modified: analysis/GOI_plots.Rmd
Modified: analysis/GTEx_genes.Rmd
Modified: analysis/Knowles2019.Rmd
Modified: analysis/Var_genes.Rmd
Modified: analysis/after_comments.Rmd
Modified: analysis/variance_scrip.Rmd
Modified: output/daplot.RDS
Modified: output/dxplot.RDS
Modified: output/epplot.RDS
Modified: output/mtplot.RDS
Modified: output/plan2plot.png
Modified: output/trplot.RDS
Modified: output/veplot.RDS
Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.
These are the previous versions of the repository in which changes were
made to the R Markdown (analysis/Knowels_trop_analysis.Rmd)
and HTML (docs/Knowels_trop_analysis.html) files. If you’ve
configured a remote Git repository (see ?wflow_git_remote),
click on the hyperlinks in the table below to view the files as they
were in that past version.
| File | Version | Author | Date | Message |
|---|---|---|---|---|
| Rmd | 4fb0cde | reneeisnowhere | 2024-01-02 | adding mean/var by concentration and var.test as significance |
| html | c2decdd | reneeisnowhere | 2023-12-20 | Build site. |
| Rmd | 0ba6ddb | reneeisnowhere | 2023-12-20 | adding HSV gene list |
| html | 896cb7b | reneeisnowhere | 2023-12-19 | Build site. |
| Rmd | cd8fd41 | reneeisnowhere | 2023-12-19 | updates to figures and analysis |
| html | 856e5f0 | reneeisnowhere | 2023-12-18 | Build site. |
| Rmd | 4d40dbf | reneeisnowhere | 2023-12-18 | updated Knowels replication GOI |
| Rmd | 1bcddcf | reneeisnowhere | 2023-12-18 | updates for supp |
| html | fbc476b | reneeisnowhere | 2023-12-01 | Build site. |
| Rmd | 80e90ab | reneeisnowhere | 2023-12-01 | added GOBP data |
| html | 312c8f4 | reneeisnowhere | 2023-11-28 | Build site. |
| Rmd | 8606776 | reneeisnowhere | 2023-11-28 | updated with GO on Highly variable genes |
| html | b651aa9 | reneeisnowhere | 2023-11-27 | Build site. |
| Rmd | 522ca8c | reneeisnowhere | 2023-11-27 | adding more analysis |
| html | b474072 | reneeisnowhere | 2023-11-21 | Build site. |
| Rmd | 5c45b92 | reneeisnowhere | 2023-11-21 | adding knowles data again |
| html | b4d55c4 | reneeisnowhere | 2023-11-21 | Build site. |
| Rmd | b1b9563 | reneeisnowhere | 2023-11-21 | adding logcpm with knowles data |
| html | b442590 | reneeisnowhere | 2023-11-21 | Build site. |
| Rmd | b464f89 | reneeisnowhere | 2023-11-21 | updates to links again |
| html | 19a3502 | reneeisnowhere | 2023-11-21 | Build site. |
| Rmd | d17d270 | reneeisnowhere | 2023-11-21 | adding links |
| html | c72467c | reneeisnowhere | 2023-11-09 | Build site. |
| Rmd | 8a6ebc1 | reneeisnowhere | 2023-11-09 | updates on plots |
| html | 9af9df6 | reneeisnowhere | 2023-11-09 | Build site. |
| Rmd | 60c64d1 | reneeisnowhere | 2023-11-09 | adding boxplots |
| html | d12232a | reneeisnowhere | 2023-11-07 | Build site. |
| Rmd | 441f82b | reneeisnowhere | 2023-11-07 | adding more code |
| html | cae46a9 | reneeisnowhere | 2023-11-07 | Build site. |
| html | bd0342c | reneeisnowhere | 2023-11-07 | Build site. |
| Rmd | 453ebe6 | reneeisnowhere | 2023-11-07 | adding code |
| Rmd | d6ecce9 | reneeisnowhere | 2023-11-07 | adding code |
| html | ae9124e | reneeisnowhere | 2023-10-30 | Build site. |
| Rmd | 74c2dc1 | reneeisnowhere | 2023-10-30 | updated |
| Rmd | d970e84 | reneeisnowhere | 2023-10-30 | adding more analysis |
library(tidyverse)
library(ggsignif)
library(cowplot)
library(ggpubr)
library(scales)
library(sjmisc)
library(kableExtra)
library(broom)
library(ComplexHeatmap)
library(ggVennDiagram)
library(biomaRt)
library(limma)
library(edgeR)
library(RColorBrewer)palette_colors_mine <- colorRampPalette(colors = c("green","white","purple","red" ))(60)
scales::show_col(palette_colors_mine)
Knowles data analysis
Here I will attempt to recreate my correlation analysis on the knowles data using their troponin and RNAseq log2cpm.
### genes I want to know about
interest_genes <- read.csv("output/GOI_genelist.txt", row.names = 1)
trop_knowles <- read.csv("output/trop_knowles_fun.csv", row.names = 1)
Knowles_log2cpm <- readRDS("data/Knowles_log2cpm_real.RDS")
trop0.625 <- trop_knowles %>%
filter(dosage <1)
store <- Knowles_log2cpm %>%
dplyr::select( 'ESGN',ends_with(c('0.625', '0'))) %>%
dplyr::filter(ESGN %in% interest_genes$ensembl_gene_id) %>%
pivot_longer(cols=!ESGN, names_to = "ind", values_to = "counts") %>%
separate(ind,into=c("cell_line","dosage"), sep = ":") %>%
mutate(dosage = as.numeric(dosage)) %>%
full_join(., trop0.625, by=c("cell_line", "dosage")) %>%
group_by(cell_line) %>%
full_join(., interest_genes, by = c("ESGN" = "ensembl_gene_id"))
###new graph stuff
for (gene in interest_genes$ensembl_gene_id){
gene_plot <- store %>%
dplyr::filter(ESGN == gene) %>%
ggplot(., aes(x=troponin, y=counts))+
geom_point(aes(col=cell_line))+
geom_smooth(method="lm")+
facet_wrap(hgnc_symbol~dosage, scales="free")+
theme_classic()+
xlab("troponin I expression") +
ylab("Gene counts in log2 cpm") +
ggtitle(expression(paste("Correlation between counts and troponin I Knowles")))+
scale_color_manual(values = palette_colors_mine, aesthetics = c("color", "fill"), guide=FALSE)+
# guides(fill="none")+
ggpubr:: stat_cor(method="spearman",
# cor.coef.name="rho",
aes(label = paste(..r.label.., ..p.label.., sep = "~`,\n`~")),
color = "black",
label.x.npc = 0.01,
label.y.npc=0.01,
size = 3)+
theme(plot.title = element_text(size = rel(1.5), hjust = 0.5,face = "bold"),
axis.title = element_text(size = 15, color = "black"),
axis.ticks = element_line(size = 1.5),
axis.text = element_text(size = 8, color = "black", angle = 20),
strip.text.x = element_text(size = 12, color = "black", face = "italic"))
print(gene_plot)
}
| Version | Author | Date |
|---|---|---|
| bd0342c | reneeisnowhere | 2023-11-07 |
| Version | Author | Date |
|---|---|---|
| bd0342c | reneeisnowhere | 2023-11-07 |
Knowles Boxplots of Fig9 genes
Knowles_log2cpm_box <- readRDS("data/Knowles_log2cpm_real.RDS")
store_box <- Knowles_log2cpm_box %>%
# dplyr::select( 'ESGN',ends_with(c('0.625', '0'))) %>%
dplyr::filter(ESGN %in% interest_genes$ensembl_gene_id) %>%
pivot_longer(cols=!ESGN, names_to = "ind", values_to = "counts") %>%
separate(ind,into=c("cell_line","dosage"), sep = ":") %>%
mutate(dosage = as.numeric(dosage)) %>%
# full_join(., trop0.625, by=c("cell_line", "dosage")) %>%
group_by(cell_line) %>%
full_join(., interest_genes, by = c("ESGN" = "ensembl_gene_id"))
store_box %>%
mutate(dosage=factor(dosage, levels=c('0','0.000', '0.625','1.25', '2.5','5'))) %>%
ggplot(., aes(x=dosage,y=counts), group=dosage)+
geom_boxplot()+
facet_wrap(~hgnc_symbol)
| Version | Author | Date |
|---|---|---|
| 9af9df6 | reneeisnowhere | 2023-11-09 |
RNA-seq trial analysis
Analysis of expressed genes
RNA_seq_trial<- readRDS("data/RNA_seq_trial.RDS")
all_cpmcount <- read_table("data/Counts_RNA_ERMatthews.txt")
cpm_count_main <- readRDS("data/cpmcount.RDS") %>% rownames_to_column(var = "ENTREZID")
colnames(cpm_count_main) <- colnames(all_cpmcount)
test_run_sample_list <- read.csv("data/test_run_sample_list.txt", row.names = 1)
colnames(RNA_seq_trial) <- c("ENTREZID",test_run_sample_list$Sample_ID)
lcpm_trial <- RNA_seq_trial %>%
column_to_rownames("ENTREZID") %>%
cpm(., log=TRUE) %>%
as.data.frame() #%>%
row_means <- rowMeans(lcpm_trial)
x_trial <- lcpm_trial[row_means > 0,]
dim(x_trial)[1] 13277 4list_genes_trial <- rownames(x_trial)
ggVennDiagram::ggVennDiagram(list(list_genes_trial, cpm_count_main$ENTREZID),
category.names = c("Trialgenes","Maingenes"),
show_intersect = TRUE,
set_color = "black",
label = "count",
label_percent_digit = 1,
label_size = 4,
label_alpha = 0,
label_color = "black",
edge_lty = "solid", set_size = 4.5)#+Correlation of counts files
lcpm_trial_full <- RNA_seq_trial %>%
column_to_rownames("ENTREZID") %>%
cpm(., log=TRUE) %>%
as.data.frame() %>%
rownames_to_column(var = "ENTREZID")
lcpm_trial_full %>%
column_to_rownames(var="ENTREZID") %>%
cor(.) %>%
Heatmap(.,layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 10))})
| Version | Author | Date |
|---|---|---|
| ae9124e | reneeisnowhere | 2023-10-30 |
lcpm_main <- all_cpmcount %>%
column_to_rownames("ENTREZID") %>%
cpm(., log=TRUE) %>%
as.data.frame() %>%
rownames_to_column(var = "ENTREZID") %>%
dplyr::select(ENTREZID, all_of(starts_with("DOX"))) %>%
dplyr::select(ENTREZID, all_of(ends_with("3h")))
combined_data <- lcpm_main %>%
full_join(., lcpm_trial_full, by= "ENTREZID") %>%
column_to_rownames("ENTREZID") %>%
dplyr::select(starts_with("DOX"),`3hr_0.5`)%>%
cor(.,)
Heatmap(combined_data,column_title = "Full gene list",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(combined_data, i, j)), x, y,
gp = gpar(fontsize = 10))})
only79_ind <- lcpm_main %>%
full_join(., lcpm_trial_full, by= "ENTREZID") %>%
dplyr::select(ENTREZID,'3hr_0.5',"DOX.4.3h") %>%
column_to_rownames("ENTREZID") %>%
cor(.,)
Heatmap(only79_ind,column_title = "Full gene list_79",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(only79_ind, i, j)), x, y,
gp = gpar(fontsize = 10))})
lcpm_main_veh <- all_cpmcount %>%
column_to_rownames("ENTREZID") %>%
cpm(., log=TRUE) %>%
as.data.frame() %>%
rownames_to_column(var = "ENTREZID") %>%
dplyr::select(ENTREZID, all_of(c(starts_with("DOX"),starts_with("VEH")))) %>%
dplyr::select(ENTREZID, all_of(ends_with("3h")))
combined_data_veh<- lcpm_main_veh %>%
full_join(., lcpm_trial_full, by= "ENTREZID") %>%
column_to_rownames("ENTREZID") %>%
cor(.,)
Heatmap(combined_data_veh, column_title = "all genes in list, no filtering",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(combined_data_veh, i, j)), x, y,
gp = gpar(fontsize = 8))})
| Version | Author | Date |
|---|---|---|
| ae9124e | reneeisnowhere | 2023-10-30 |
lcpm_trial_filter_main <- lcpm_trial_full %>%
filter(ENTREZID %in% cpm_count_main$ENTREZID)
lcpm_trial_filter_main %>%
column_to_rownames(var="ENTREZID") %>%
cor(.) %>%
Heatmap(.,column_title = "Using 14,084 expressed genes from Main data",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 8))})
| Version | Author | Date |
|---|---|---|
| ae9124e | reneeisnowhere | 2023-10-30 |
lcpm_trial_filter <- lcpm_trial_full %>%
filter(ENTREZID %in% list_genes_trial)
lcpm_trial_filter %>%
column_to_rownames(var="ENTREZID") %>%
cor(.) %>%
Heatmap(.,column_title = "Using 13277 expressed genes",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 8))})
| Version | Author | Date |
|---|---|---|
| ae9124e | reneeisnowhere | 2023-10-30 |
lcpm_main_filter_trial <- lcpm_main_veh %>%
filter(ENTREZID %in% list_genes_trial)
lcpm_trial_filter %>%
full_join(., lcpm_main_filter_trial, by = "ENTREZID") %>%
column_to_rownames(var="ENTREZID") %>%
cor(.) %>%
Heatmap(.,column_title = "Using 13277 expressed genes",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 8))})
| Version | Author | Date |
|---|---|---|
| ae9124e | reneeisnowhere | 2023-10-30 |
lcpm_trial_filter_main %>%
left_join(., lcpm_main, by = "ENTREZID") %>%
column_to_rownames(var="ENTREZID") %>%
dplyr::select(DOX.4.3h,starts_with(("3hr")))%>%
cor(.) %>%
Heatmap(.,column_title = "Using 14084 expressed genes, just 79-1",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 8))})
| Version | Author | Date |
|---|---|---|
| bd0342c | reneeisnowhere | 2023-11-07 |
hr3_indv4 <- lcpm_trial_filter_main %>%
left_join(., lcpm_main, by = "ENTREZID") %>%
column_to_rownames(var="ENTREZID") %>%
dplyr::select(DOX.4.3h,`3hr_0.5`,`3hr_0.0`)%>%
cor(.) %>%
Heatmap(.,column_title = "Using 14084 expressed genes, just 79-1",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 8))})
plot(hr3_indv4)
| Version | Author | Date |
|---|---|---|
| bd0342c | reneeisnowhere | 2023-11-07 |
correlation heatmap of 3hr Dox 1-6 individuals and trial data
lcpm_trial_filter_main %>%
left_join(., lcpm_main, by = "ENTREZID") %>%
column_to_rownames(var="ENTREZID") %>%
dplyr::select(starts_with("DOX"),`3hr_0.5`)%>%
cor(.) %>%
Heatmap(.,column_title = "Using 14084 expressed genes, just 79-1 with all 3 hour samples",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 8))})
| Version | Author | Date |
|---|---|---|
| 9af9df6 | reneeisnowhere | 2023-11-09 |
lcpm_main %>%
left_join(., lcpm_trial_full, by = "ENTREZID") %>%
column_to_rownames(var="ENTREZID") %>%
dplyr::select(starts_with("DOX"),`3hr_0.5`)%>%
cor(.) %>%
Heatmap(.,column_title = "all 29395 genes expriment with trial 0.5 uM",
layer_fun = function(j, i, x, y, width, height, fill) {
grid.text(sprintf("%.3f", pindex(., i, j)), x, y,
gp = gpar(fontsize = 8))})
| Version | Author | Date |
|---|---|---|
| b4d55c4 | reneeisnowhere | 2023-11-21 |
barplots
backGL <-read_csv("data/backGL.txt",
col_types = cols(...1 = col_skip()))
GOI_genelist <- read.csv("output/GOI_genelist.txt", row.names = 1)
cpm_boxplot_trial <-function(lcpm_trial, GOI, ylab) {
##GOI needs to be ENTREZID
df_plot <- lcpm_trial %>%
dplyr::filter(rownames(.)== GOI) %>%
pivot_longer(everything(),
names_to = "treatment",
values_to = "counts") %>%
separate(treatment, c("time","conc"), sep= "_") %>%
mutate(conc = factor(conc,levels=c('0.0','0.1','0.5','1.0'), labels = c ("NT", "0.1 uM", "0.5 uM", "1.0 uM")))
plota <- ggplot2::ggplot(df_plot, aes(x=conc, y= counts))+
geom_col(position="identity")+
theme_bw()+
ylab(ylab)+
xlab("")+
ggtitle(paste(GOI))+
theme(
# strip.background = element_rect(fill = "white",linetype=1, linewidth = 0.5),
plot.title = element_text(size=12,hjust = 0.5,face="bold"),
axis.title = element_text(size = 10, color = "black"),
axis.ticks = element_line(linewidth = 1.0),
panel.background = element_rect(colour = "black", size=1),
# axis.text.x = element_blank(),
strip.text.x = element_text(margin = margin(2,0,2,0, "pt"),face = "bold"))
print(plota)
}
for (g in seq(1:11)){
datafilter <- GOI_genelist
a <- GOI_genelist[g,3]
# b <- datafilter[g,1]
cpm_boxplot_trial(lcpm_trial,GOI=datafilter[g,1],
ylab =bquote(~italic(.(a))~log[2]~"cpm "))
} 
above is expression of trial RNA seq data
Knowles log2cpm 24hr and my log2cpm 24hr
### Creating new interest genes for supplemental figure
# # SNP_genestop50 <- read.csv("output/TOP_50SNPreffile.csv", row.names = 1)
# backGL <- read.csv("data/backGL.txt", row.names = 1)
#
# DOX_de_genes_interest <- data.frame("hgnc_symbol"= c("PELI2","LGALS3", "PCCA", "SORT1", "GPSM2", "CLCC1", "LNPK", "GRAMD4","TTC38","CDPF1", "CYREN", "LPL", "CELSR1","PPIP5K2", "TNS2", "ZNF740", "SLC28A3", "RMI1", "FRS2", "HDDC2"))
# #
# #
# DOX_de_genes_interest %>%
# left_join(., backGL, by= c("hgnc_symbol"="SYMBOL")) %>%
# dplyr::select(!hgnc_symbol.y) %>%
# write.csv(.,"output/DOX_de_goi.csv")
DOX_de_genes_interest <- read.csv("output/DOX_de_goi.csv", row.names = 1)
kcpm <- Knowles_log2cpm_box %>%
dplyr::filter(ESGN %in% DOX_de_genes_interest$ensembl_gene_id) %>%
pivot_longer(cols=!ESGN, names_to = "ind", values_to = "counts") %>%
separate(ind,into=c("cell_line","dosage"), sep = ":") %>%
mutate(dosage = as.numeric(dosage)) %>%
# full_join(., trop0.625, by=c("cell_line", "dosage")) %>%
group_by(cell_line) %>%
full_join(., DOX_de_genes_interest, by = c("ESGN" = "ensembl_gene_id"))%>%
mutate(dosage=factor(dosage, levels=c('0','0.000', '0.625','1.25', '2.5','5'))) %>%
dplyr::filter(dosage==("0")|dosage == "0.625") %>%
mutate(expr="K")
lcpm_24h <- all_cpmcount %>%
column_to_rownames("ENTREZID") %>%
cpm(., log=TRUE) %>%
as.data.frame() %>%
rownames_to_column(var = "ENTREZID") %>%
dplyr::select(ENTREZID, all_of(starts_with(c("DOX","VEH")))) %>%
dplyr::select(ENTREZID, all_of(ends_with("24h"))) %>%
dplyr::filter(ENTREZID %in% DOX_de_genes_interest$ENTREZID) %>%
pivot_longer(cols=!ENTREZID, names_to = "ind", values_to = "counts") %>% mutate(ENTREZID = as.numeric(ENTREZID)) %>%
full_join(., DOX_de_genes_interest, by = c("ENTREZID"="ENTREZID")) %>%
mutate(expr="ME") %>%
rename("ESGN"="ensembl_gene_id") %>%
separate(ind, into = c("dosage","cell_line",NA)) %>%
mutate(dosage=case_match(dosage,"DOX"~"0.5", .default = dosage))
lcpm_24h %>%
rbind(.,kcpm) %>%
mutate(dosage=factor(dosage, levels=c('0','0.625',"VEH","0.5"))) %>%
ggplot(., aes(x=dosage,y=counts), group=expr)+
geom_boxplot()+
facet_wrap(~hgnc_symbol, scales="free_y", nrow=4, ncol = 6 )#+
# geom_signif(
# comparisons = list(
# c('0', '0.5'),
# c('0', '0.625'),
# c('0.5','0.625')
# ),
# test = "t.test",
# tip_length = 0.01,
# map_signif_level = FALSE,
# textsize = 4,
# step_increase = 0.3
# ) Replication of variance figures using Knowels data
# saveRDS(store_var, "data/Knowles_variation_data.RDS")
# store_var <- Knowles_log2cpm %>%
# dplyr::select( 'ESGN',ends_with(c('0.625', '0'))) %>%
# rowwise() %>%
# mutate(mean_DOX=mean(c_across(ends_with('0.625'))),
# var_DOX=var(c_across(ends_with('0.625'))),
# mean_NT=mean(c_across(ends_with('0'))),
# var_NT=var(c_across(ends_with('0')))) %>%
# mutate(data=tidy(var.test(c_across(ends_with("0.625")),c_across(ends_with("0")))))# %>%
# dplyr::select("ESGN","mean_DOX","var_DOX","mean_NT", "var_NT","data")
store_var <- readRDS("data/Knowles_variation_data.RDS")
knowlesdrug<- store_var %>%
dplyr::select("ESGN","mean_DOX","var_DOX","mean_NT", "var_NT") %>%
pivot_longer(cols = !"ESGN", names_to = "short", values_to = "values") %>%
separate(short, into=c("calc","treatment")) #%>%
knowlesdrug %>%
as.data.frame() %>%
dplyr::filter(calc == "mean") %>%
ggplot(., aes(x= treatment, y=values))+
geom_boxplot()+
ggtitle("Knowles Means across all genes")+
geom_signif(
comparisons = list(
c("DOX", "NT")),
test = "t.test",
tip_length = 0.01,
map_signif_level = FALSE
# textsize = 4,
# # y_position = 11,
# step_increase = 0.05
)+
theme_bw() +
# xlab(" ") +
ylab(expression("counts log"[2] ~ "cpm ")) +
theme(
strip.background = element_rect(
fill = "white",
linetype = 1,
linewidth = 0.5
),
plot.title = element_text(size = 12, hjust = 0.5, face = "bold"),
axis.title = element_text(size = 10, color = "black"),
axis.ticks = element_line(linewidth = 1.0),
panel.background = element_rect(colour = "black", size = 1),
# axis.text.x = element_blank(),
strip.text.x = element_text(margin = margin(2, 0, 2, 0, "mm"), face = "bold")
)
knowlesdrug %>%
as.data.frame() %>%
dplyr::filter(calc == "var") %>%
ggplot(., aes(x= treatment, y=values))+
geom_boxplot(outlier.shape= NA)+
ggtitle(" Knowles Variance across all genes")+
geom_signif(
comparisons = list(
c("DOX", "NT")),
test = "var.test",
tip_length = 0.01,
y_position = 0.5,
# vjust=1,
map_signif_level = FALSE)+
coord_cartesian(ylim = c(NA, 1.5), expand = TRUE)+
theme_bw() +
# xlab(" ") +
ylab(expression("counts log"[2] ~ "cpm ")) +
theme(
strip.background = element_rect(
fill = "white",
linetype = 1,
linewidth = 0.5
),
plot.title = element_text(size = 12, hjust = 0.5, face = "bold"),
axis.title = element_text(size = 10, color = "black"),
axis.ticks = element_line(linewidth = 1.0),
panel.background = element_rect(colour = "black", size = 1),
# axis.text.x = element_blank(),
strip.text.x = element_text(margin = margin(2, 0, 2, 0, "mm"), face = "bold")
)
# store_varconc <- Knowles_log2cpm %>%
# # dplyr::select( 'ESGN',ends_with(c('0.625', '0'))) %>%
# rowwise() %>%
# mutate(mean_DOX_0.625=mean(c_across(ends_with('0.625'))),
# var_DOX_0.625=var(c_across(ends_with('0.625'))),
# mean_NT=mean(c_across(ends_with('0'))),
# var_NT=var(c_across(ends_with('0'))),
# mean_DOX_1.25=mean(c_across(ends_with('1.25'))),
# var_DOX_1.25=var(c_across(ends_with('1.25'))),
# mean_DOX_2.5=mean(c_across(ends_with('2.5'))),
# var_DOX_2.5=var(c_across(ends_with('2.5'))),
# mean_DOX_5=mean(c_across(ends_with(':5'))),
# var_DOX_5=var(c_across(ends_with(':5')))) %>%
# # mutate(data1=tidy(var.test(c_across(ends_with("0.625")),c_across(ends_with("0")))))# %>%
# dplyr::select("ESGN","mean_DOX_0.625","var_DOX_0.625","mean_NT", "var_NT","mean_DOX_1.25","var_DOX_1.25","mean_DOX_2.5","var_DOX_2.5","mean_DOX_5","var_DOX_5")
# saveRDS(store_varconc,"data/Knowles_variation_data_conc.RDS")
store_varconc <- readRDS("data/Knowles_variation_data_conc.RDS")
# knowlesdrug<-
store_varconc %>%
pivot_longer(cols = !"ESGN", names_to = "short", values_to = "values") %>%
separate(short, into=c("calc","treatment","conc"), sep = "_") %>%
mutate(conc= if_else(is.na(conc),"0",conc)) %>%
as.data.frame() %>%
dplyr::filter(calc == "mean") %>%
group_by(conc) %>%
ggplot(., aes(x= conc, y=values), group=treatment)+
geom_boxplot(outlier.shape= NA)+
ggtitle("Knowles Means across all genes")+
geom_signif(
comparisons = list(
c("0", "0.625"),
c("0", "1.25"),
c("0", "2.5"),
c("0", "5")),
test = "t.test",
tip_length = 0.01,
# y_position = 0.2,
step_increase = 0.04,
map_signif_level = FALSE)+
theme_bw() +
# xlab(" ") +
ylab(expression("counts log"[2] ~ "cpm ")) +
theme(
strip.background = element_rect(
fill = "white",
linetype = 1,
linewidth = 0.5
),
plot.title = element_text(size = 12, hjust = 0.5, face = "bold"),
axis.title = element_text(size = 10, color = "black"),
axis.ticks = element_line(linewidth = 1.0),
panel.background = element_rect(colour = "black", size = 1),
# axis.text.x = element_blank(),
strip.text.x = element_text(margin = margin(2, 0, 2, 0, "mm"), face = "bold")
)
store_varconc %>%
pivot_longer(cols = !"ESGN", names_to = "short", values_to = "values") %>%
separate(short, into=c("calc","treatment","conc"), sep = "_") %>%
mutate(conc= if_else(is.na(conc),"0",conc)) %>%
as.data.frame() %>%
dplyr::filter(calc == "var") %>%
group_by(conc) %>%
ggplot(., aes(x= conc, y=values), group=treatment)+
geom_boxplot(outlier.shape= NA)+
ggtitle(" Knowles Variance across all genes")+
geom_signif(
comparisons = list(
c("0", "0.625"),
c("0", "1.25"),
c("0", "2.5"),
c("0", "5")),
test = "var.test",
tip_length = 0.01,
y_position = 0.2,
step_increase = 0.02,
map_signif_level = FALSE)+
# ylim(NA,1.2)+
coord_cartesian(ylim = c(NA, 2.1))+
theme_bw() +
# xlab(" ") +
ylab(expression("counts log"[2] ~ "cpm ")) +
theme(
strip.background = element_rect(
fill = "white",
linetype = 1,
linewidth = 0.5
),
plot.title = element_text(size = 12, hjust = 0.5, face = "bold"),
axis.title = element_text(size = 10, color = "black"),
axis.ticks = element_line(linewidth = 1.0),
panel.background = element_rect(colour = "black", size = 1),
# axis.text.x = element_blank(),
strip.text.x = element_text(margin = margin(2, 0, 2, 0, "mm"), face = "bold")
)
qvalue data
library(qvalue)
# p_list <- map_df(store_var$data,~as.data.frame(.x$p.value))
# rownames(p_list) <- store_var$ESGN
p_list <- store_var %>%
unnest(data) %>%
dplyr::select(ESGN,statistic,p.value)
estDOXk <- qvalue(p_list$p.value)
hist(estDOXk)
| Version | Author | Date |
|---|---|---|
| 312c8f4 | reneeisnowhere | 2023-11-28 |
plot(estDOXk)
| Version | Author | Date |
|---|---|---|
| 312c8f4 | reneeisnowhere | 2023-11-28 |
summary(estDOXk)
Call:
qvalue(p = p_list$p.value)
pi0: 0.3993136
Cumulative number of significant calls:
<1e-04 <0.001 <0.01 <0.025 <0.05 <0.1 <1
p-value 1919 2762 4065 4832 5533 6453 12317
q-value 1616 2447 3895 4810 5723 6956 12317
local FDR 1143 1759 2724 3313 3800 4507 12317knowlesvar <- data.frame("ESGN"=p_list$ESGN,"pvalues"=estDOXk$pvalues,"qvalues"=estDOXk$qvalues,"lfdr"= estDOXk$lfdr)
intersecting_K <- knowlesvar %>%
filter(qvalues<0.1)
my_qval_list24 <- readRDS("data/qval24hr.RDS")
EPI508_list <- my_qval_list24 %>%
dplyr::select(ENTREZID,EPIqvalues) %>%
filter(EPIqvalues<0.1) %>%
dplyr::select(ENTREZID) %>%
mutate(ENTREZID=as.numeric(ENTREZID)) %>%
left_join(.,backGL, by="ENTREZID")
Knowlesvarlist <- readRDS("data/Knowlesvarlist.RDS")
# Knowlesvarlist<- getBM(attributes=my_attributes,filters ='ensembl_gene_id',values = intersecting_K$ESGN, mart = ensembl)
length(intersect(EPI508_list$ENTREZID,Knowlesvarlist$entrezgene_id))[1] 367intersect_genes <- EPI508_list %>%
dplyr::filter(ENTREZID %in% Knowlesvarlist$entrezgene_id)
highly_var_genelist <- intersect(EPI508_list$ENTREZID,Knowlesvarlist$entrezgene_id)
saveRDS(highly_var_genelist,"data/highly_var_genelist.RDS")
intersect_genes %>%
kable(.,caption = "EPI Highly variable genes found in Knowles highly variable DOX genes") %>%
kable_paper("striped", full_width = FALSE) %>%
kable_styling(full_width = TRUE, bootstrap_options = c("striped","hover")) %>%
scroll_box(width = "100%", height = "400px")| ENTREZID | SYMBOL | ensembl_gene_id | hgnc_symbol |
|---|---|---|---|
| 49856 | WRAP73 | ENSG00000116213 | WRAP73 |
| 23463 | ICMT | ENSG00000116237 | ICMT |
| 5195 | PEX14 | ENSG00000142655 | PEX14 |
| 57085 | AGTRAP | ENSG00000177674 | AGTRAP |
| 23207 | PLEKHM2 | ENSG00000116786 | PLEKHM2 |
| 79363 | CPLANE2 | ENSG00000291382 | CPLANE2 |
| 55160 | ARHGEF10L | ENSG00000074964 | ARHGEF10L |
| 55616 | ASAP3 | ENSG00000282854 | ASAP3 |
| 57095 | PITHD1 | ENSG00000057757 | PITHD1 |
| 11313 | LYPLA2 | ENSG00000011009 | LYPLA2 |
| 84065 | TMEM222 | ENSG00000186501 | TMEM222 |
| 23673 | STX12 | ENSG00000117758 | STX12 |
| 56063 | TMEM234 | ENSG00000160055 | TMEM234 |
| 3065 | HDAC1 | ENSG00000116478 | HDAC1 |
| 127544 | RNF19B | ENSG00000116514 | RNF19B |
| 113444 | SMIM12 | ENSG00000163866 | SMIM12 |
| 27095 | TRAPPC3 | ENSG00000054116 | TRAPPC3 |
| 112950 | MED8 | ENSG00000159479 | MED8 |
| 9670 | IPO13 | ENSG00000117408 | IPO13 |
| 149483 | CCDC17 | ENSG00000159588 | CCDC17 |
| 387338 | NSUN4 | ENSG00000117481 | NSUN4 |
| 8543 | LMO4 | ENSG00000143013 | LMO4 |
| 64858 | DCLRE1B | ENSG00000118655 | DCLRE1B |
| 128077 | LIX1L | ENSG00000271601 | LIX1L |
| 388695 | LYSMD1 | ENSG00000163155 | LYSMD1 |
| 6944 | VPS72 | ENSG00000163159 | VPS72 |
| 65005 | MRPL9 | ENSG00000143436 | MRPL9 |
| 4000 | LMNA | ENSG00000160789 | LMNA |
| 11266 | DUSP12 | ENSG00000081721 | DUSP12 |
| 261726 | TIPRL | ENSG00000143155 | TIPRL |
| 5279 | PIGC | ENSG00000135845 | PIGC |
| 83479 | DDX59 | ENSG00000118197 | DDX59 |
| 134 | ADORA1 | ENSG00000163485 | ADORA1 |
| 64853 | AIDA | ENSG00000186063 | AIDA |
| 163859 | SDE2 | ENSG00000143751 | SDE2 |
| 5664 | PSEN2 | ENSG00000143801 | PSEN2 |
| 65094 | JMJD4 | ENSG00000081692 | JMJD4 |
| 126731 | CCSAP | ENSG00000154429 | CCSAP |
| 22796 | COG2 | ENSG00000135775 | COG2 |
| 79723 | SUV39H2 | ENSG00000152455 | SUV39H2 |
| 253430 | IPMK | ENSG00000151151 | IPMK |
| 26091 | HERC4 | ENSG00000148634 | HERC4 |
| 219738 | FAM241B | ENSG00000171224 | FAM241B |
| 11319 | ECD | ENSG00000122882 | ECD |
| 5532 | PPP3CB | ENSG00000107758 | PPP3CB |
| 79933 | SYNPO2L | ENSG00000166317 | SYNPO2L |
| 27063 | ANKRD1 | ENSG00000148677 | ANKRD1 |
| 118924 | FRA10AC1 | ENSG00000148690 | FRA10AC1 |
| 282991 | BLOC1S2 | ENSG00000196072 | BLOC1S2 |
| 10360 | NPM3 | ENSG00000107833 | NPM3 |
| 9937 | DCLRE1A | ENSG00000198924 | DCLRE1A |
| 9184 | BUB3 | ENSG00000154473 | BUB3 |
| 161 | AP2A2 | ENSG00000280759 | AP2A2 |
| 7748 | ZNF195 | ENSG00000005801 | ZNF195 |
| 10612 | TRIM3 | ENSG00000110171 | TRIM3 |
| 23647 | ARFIP2 | ENSG00000132254 | ARFIP2 |
| 65975 | STK33 | ENSG00000130413 | STK33 |
| 113174 | SAAL1 | ENSG00000166788 | SAAL1 |
| 627 | BDNF | ENSG00000176697 | BDNF |
| 79797 | ZNF408 | ENSG00000175213 | ZNF408 |
| 10978 | CLP1 | ENSG00000172409 | CLP1 |
| 55048 | VPS37C | ENSG00000167987 | VPS37C |
| 5436 | POLR2G | ENSG00000168002 | POLR2G |
| 144097 | SPINDOC | ENSG00000168005 | SPINDOC |
| 57410 | SCYL1 | ENSG00000142186 | SCYL1 |
| 10524 | KAT5 | ENSG00000172977 | KAT5 |
| 25855 | BRMS1 | ENSG00000174744 | BRMS1 |
| 10432 | RBM14 | ENSG00000239306 | RBM14 |
| 338692 | ANKRD13D | ENSG00000172932 | ANKRD13D |
| 5883 | RAD9A | ENSG00000172613 | RAD9A |
| 5499 | PPP1CA | ENSG00000172531 | PPP1CA |
| 2950 | GSTP1 | ENSG00000084207 | GSTP1 |
| 116985 | ARAP1 | ENSG00000186635 | ARAP1 |
| 5612 | THAP12 | ENSG00000137492 | THAP12 |
| 56946 | EMSY | ENSG00000158636 | EMSY |
| 282679 | AQP11 | ENSG00000178301 | AQP11 |
| 51585 | PCF11 | ENSG00000165494 | PCF11 |
| 60492 | CCDC90B | ENSG00000137500 | CCDC90B |
| 9440 | MED17 | ENSG00000042429 | MED17 |
| 54851 | ANKRD49 | ENSG00000168876 | ANKRD49 |
| 10929 | SRSF8 | ENSG00000263465 | SRSF8 |
| 5049 | PAFAH1B2 | ENSG00000168092 | PAFAH1B2 |
| 219902 | TLCD5 | ENSG00000181264 | TLCD5 |
| 219899 | TBCEL | ENSG00000154114 | TBCEL |
| 9538 | EI24 | ENSG00000149547 | EI24 |
| 219833 | KCNJ5-AS1 | ENSG00000174370 | KCNJ5-AS1 |
| 57102 | C12orf4 | ENSG00000047621 | C12orf4 |
| 8079 | MLF2 | ENSG00000089693 | MLF2 |
| 25977 | NECAP1 | ENSG00000089818 | NECAP1 |
| 79657 | RPAP3 | ENSG00000005175 | RPAP3 |
| 55652 | SLC48A1 | ENSG00000211584 | SLC48A1 |
| 1019 | CDK4 | ENSG00000135446 | CDK4 |
| 23041 | MON2 | ENSG00000061987 | MON2 |
| 29110 | TBK1 | ENSG00000183735 | TBK1 |
| 253827 | MSRB3 | ENSG00000174099 | MSRB3 |
| 117177 | RAB3IP | ENSG00000127328 | RAB3IP |
| 22822 | PHLDA1 | ENSG00000139289 | PHLDA1 |
| 89795 | NAV3 | ENSG00000067798 | NAV3 |
| 121053 | NOPCHAP1 | ENSG00000151131 | NOPCHAP1 |
| 1407 | CRY1 | ENSG00000008405 | CRY1 |
| 51228 | GLTP | ENSG00000139433 | GLTP |
| 400073 | C12orf76 | ENSG00000174456 | C12orf76 |
| 5564 | PRKAB1 | ENSG00000111725 | PRKAB1 |
| 51499 | TRIAP1 | ENSG00000170855 | TRIAP1 |
| 56616 | DIABLO | ENSG00000184047 | DIABLO |
| 387893 | KMT5A | ENSG00000183955 | KMT5A |
| 11066 | SNRNP35 | ENSG00000184209 | SNRNP35 |
| 5901 | RAN | ENSG00000132341 | RAN |
| 100289635 | ZNF605 | ENSG00000196458 | ZNF605 |
| 221178 | SPATA13 | ENSG00000182957 | SPATA13 |
| 283537 | SLC46A3 | ENSG00000139508 | SLC46A3 |
| 2963 | GTF2F2 | ENSG00000188342 | GTF2F2 |
| 337867 | UBAC2 | ENSG00000134882 | UBAC2 |
| 3981 | LIG4 | ENSG00000174405 | LIG4 |
| 84945 | ABHD13 | ENSG00000139826 | ABHD13 |
| 3621 | ING1 | ENSG00000153487 | ING1 |
| 253959 | RALGAPA1 | ENSG00000174373 | RALGAPA1 |
| 54813 | KLHL28 | ENSG00000179454 | KLHL28 |
| 6617 | SNAPC1 | ENSG00000023608 | SNAPC1 |
| 123016 | TTC8 | ENSG00000165533 | TTC8 |
| 51527 | GSKIP | ENSG00000100744 | GSKIP |
| 2972 | BRF1 | ENSG00000185024 | BRF1 |
| 22893 | BAHD1 | ENSG00000140320 | BAHD1 |
| 9325 | TRIP4 | ENSG00000103671 | TRIP4 |
| 5371 | PML | ENSG00000140464 | PML |
| 60490 | PPCDC | ENSG00000138621 | PPCDC |
| 79631 | EFL1 | ENSG00000140598 | EFL1 |
| 84219 | WDR24 | ENSG00000127580 | WDR24 |
| 23059 | CLUAP1 | ENSG00000103351 | CLUAP1 |
| 2072 | ERCC4 | ENSG00000175595 | ERCC4 |
| 91949 | COG7 | ENSG00000168434 | COG7 |
| 23568 | ARL2BP | ENSG00000102931 | ARL2BP |
| 29070 | CCDC113 | ENSG00000103021 | CCDC113 |
| 8824 | CES2 | ENSG00000172831 | CES2 |
| 1874 | E2F4 | ENSG00000205250 | E2F4 |
| 6560 | SLC12A4 | ENSG00000124067 | SLC12A4 |
| 146198 | ZFP90 | ENSG00000184939 | ZFP90 |
| 54386 | TERF2IP | ENSG00000166848 | TERF2IP |
| 5119 | CHMP1A | ENSG00000131165 | CHMP1A |
| 64359 | NXN | ENSG00000280563 | NXN |
| 5048 | PAFAH1B1 | ENSG00000007168 | PAFAH1B1 |
| 388324 | INCA1 | ENSG00000196388 | INCA1 |
| 9135 | RABEP1 | ENSG00000029725 | RABEP1 |
| 57336 | ZNF287 | ENSG00000141040 | ZNF287 |
| 79736 | TEFM | ENSG00000172171 | TEFM |
| 55813 | UTP6 | ENSG00000108651 | UTP6 |
| 54475 | NLE1 | ENSG00000073536 | NLE1 |
| 5193 | PEX12 | ENSG00000108733 | PEX12 |
| 22794 | CASC3 | ENSG00000108349 | CASC3 |
| 3292 | HSD17B1 | ENSG00000108786 | HSD17B1 |
| 10614 | HEXIM1 | ENSG00000186834 | HEXIM1 |
| 114881 | OSBPL7 | ENSG00000006025 | OSBPL7 |
| 29916 | SNX11 | ENSG00000002919 | SNX11 |
| 8405 | SPOP | ENSG00000121067 | SPOP |
| 10237 | SLC35B1 | ENSG00000121073 | SLC35B1 |
| 81558 | FAM117A | ENSG00000121104 | FAM117A |
| 55316 | RSAD1 | ENSG00000136444 | RSAD1 |
| 8161 | COIL | ENSG00000121058 | COIL |
| 6426 | SRSF1 | ENSG00000136450 | SRSF1 |
| 54903 | MKS1 | ENSG00000011143 | MKS1 |
| 55771 | PRR11 | ENSG00000068489 | PRR11 |
| 284161 | GDPD1 | ENSG00000153982 | GDPD1 |
| 6198 | RPS6KB1 | ENSG00000108443 | RPS6KB1 |
| 57508 | INTS2 | ENSG00000108506 | INTS2 |
| 84923 | FAM104A | ENSG00000133193 | FAM104A |
| 55028 | C17orf80 | ENSG00000141219 | C17orf80 |
| 6730 | SRP68 | ENSG00000167881 | SRP68 |
| 9489 | PGS1 | ENSG00000087157 | PGS1 |
| 9775 | EIF4A3 | ENSG00000291508 | EIF4A3 |
| 57521 | RPTOR | ENSG00000141564 | RPTOR |
| 79643 | CHMP6 | ENSG00000176108 | CHMP6 |
| 5881 | RAC3 | ENSG00000169750 | RAC3 |
| 8780 | RIOK3 | ENSG00000101782 | RIOK3 |
| 55364 | IMPACT | ENSG00000154059 | IMPACT |
| 54531 | MIER2 | ENSG00000105556 | MIER2 |
| 126308 | MOB3A | ENSG00000172081 | MOB3A |
| 29985 | SLC39A3 | ENSG00000141873 | SLC39A3 |
| 51343 | FZR1 | ENSG00000105325 | FZR1 |
| 51588 | PIAS4 | ENSG00000105229 | PIAS4 |
| 6455 | SH3GL1 | ENSG00000141985 | SH3GL1 |
| 5609 | MAP2K7 | ENSG00000076984 | MAP2K7 |
| 79603 | CERS4 | ENSG00000090661 | CERS4 |
| 93134 | ZNF561 | ENSG00000171469 | ZNF561 |
| 126070 | ZNF440 | ENSG00000171295 | ZNF440 |
| 2193 | FARSA | ENSG00000179115 | FARSA |
| 85360 | SYDE1 | ENSG00000105137 | SYDE1 |
| 8907 | AP1M1 | ENSG00000072958 | AP1M1 |
| 54858 | PGPEP1 | ENSG00000130517 | PGPEP1 |
| 93436 | ARMC6 | ENSG00000105676 | ARMC6 |
| 79414 | LRFN3 | ENSG00000126243 | LRFN3 |
| 163087 | ZNF383 | ENSG00000188283 | ZNF383 |
| 84503 | ZNF527 | ENSG00000189164 | ZNF527 |
| 22835 | ZFP30 | ENSG00000120784 | ZFP30 |
| 284323 | ZNF780A | ENSG00000280568 | ZNF780A |
| 29950 | SERTAD1 | ENSG00000197019 | SERTAD1 |
| 90324 | CCDC97 | ENSG00000142039 | CCDC97 |
| 56006 | SMG9 | ENSG00000105771 | SMG9 |
| 7773 | ZNF230 | ENSG00000159882 | ZNF230 |
| 7769 | ZNF226 | ENSG00000167380 | ZNF226 |
| 9668 | ZNF432 | ENSG00000256087 | ZNF432 |
| 147657 | ZNF480 | ENSG00000198464 | ZNF480 |
| 112724 | RDH13 | ENSG00000278149 | RDH13 |
| 163033 | ZNF579 | ENSG00000218891 | ZNF579 |
| 147694 | ZNF548 | ENSG00000188785 | ZNF548 |
| 100293516 | ZNF587B | ENSG00000269343 | ZNF587B |
| 25799 | ZNF324 | ENSG00000083812 | ZNF324 |
| 7260 | EIPR1 | ENSG00000032389 | EIPR1 |
| 55006 | TRMT61B | ENSG00000171103 | TRMT61B |
| 253635 | GPATCH11 | ENSG00000152133 | GPATCH11 |
| 92906 | HNRNPLL | ENSG00000143889 | HNRNPLL |
| 8491 | MAP4K3 | ENSG00000011566 | MAP4K3 |
| 57504 | MTA3 | ENSG00000057935 | MTA3 |
| 53335 | BCL11A | ENSG00000119866 | BCL11A |
| 5861 | RAB1A | ENSG00000138069 | RAB1A |
| 27332 | ZNF638 | ENSG00000075292 | ZNF638 |
| 8446 | DUSP11 | ENSG00000291483 | DUSP11 |
| 1716 | DGUOK | ENSG00000114956 | DGUOK |
| 84173 | ELMOD3 | ENSG00000115459 | ELMOD3 |
| 129303 | TMEM150A | ENSG00000168890 | TMEM150A |
| 5903 | RANBP2 | ENSG00000153201 | RANBP2 |
| 10254 | STAM2 | ENSG00000115145 | STAM2 |
| 10213 | PSMD14 | ENSG00000115233 | PSMD14 |
| 115677 | NOSTRIN | ENSG00000275326 | NOSTRIN |
| 79828 | METTL8 | ENSG00000123600 | METTL8 |
| 80067 | DCAF17 | ENSG00000115827 | DCAF17 |
| 129831 | RBM45 | ENSG00000155636 | RBM45 |
| 3628 | INPP1 | ENSG00000151689 | INPP1 |
| 6775 | STAT4 | ENSG00000138378 | STAT4 |
| 9330 | GTF3C3 | ENSG00000119041 | GTF3C3 |
| 57404 | CYP20A1 | ENSG00000119004 | CYP20A1 |
| 54891 | INO80D | ENSG00000283510 | INO80D |
| 377007 | KLHL30 | ENSG00000168427 | KLHL30 |
| 4735 | SEPTIN2 | ENSG00000168385 | SEPTIN2 |
| 80023 | NRSN2 | ENSG00000125841 | NRSN2 |
| 55968 | NSFL1C | ENSG00000088833 | NSFL1C |
| 55317 | AP5S1 | ENSG00000125843 | AP5S1 |
| 64412 | GZF1 | ENSG00000125812 | GZF1 |
| 51230 | PHF20 | ENSG00000025293 | PHF20 |
| 25980 | AAR2 | ENSG00000131043 | AAR2 |
| 63905 | MANBAL | ENSG00000291969 | MANBAL |
| 10904 | BLCAP | ENSG00000166619 | BLCAP |
| 60625 | DHX35 | ENSG00000101452 | DHX35 |
| 51098 | IFT52 | ENSG00000101052 | IFT52 |
| 51006 | SLC35C2 | ENSG00000080189 | SLC35C2 |
| 10564 | ARFGEF2 | ENSG00000124198 | ARFGEF2 |
| 11054 | OGFR | ENSG00000060491 | OGFR |
| 80331 | DNAJC5 | ENSG00000101152 | DNAJC5 |
| 29104 | N6AMT1 | ENSG00000156239 | N6AMT1 |
| 84221 | SPATC1L | ENSG00000160284 | SPATC1L |
| 51586 | MED15 | ENSG00000099917 | MED15 |
| 6598 | SMARCB1 | ENSG00000275837 | SMARCB1 |
| 84700 | MYO18B | ENSG00000133454 | MYO18B |
| 402055 | SRRD | ENSG00000100104 | SRRD |
| 84164 | ASCC2 | ENSG00000100325 | ASCC2 |
| 23780 | APOL2 | ENSG00000128335 | APOL2 |
| 129138 | ANKRD54 | ENSG00000100124 | ANKRD54 |
| 9463 | PICK1 | ENSG00000100151 | PICK1 |
| 84247 | RTL6 | ENSG00000188636 | RTL6 |
| 132001 | TAMM41 | ENSG00000279643 | TAMM41 |
| 23609 | MKRN2 | ENSG00000075975 | MKRN2 |
| 22908 | SACM1L | ENSG00000211456 | SACM1L |
| 51385 | ZNF589 | ENSG00000164048 | ZNF589 |
| 64925 | CCDC71 | ENSG00000177352 | CCDC71 |
| 11070 | TMEM115 | ENSG00000126062 | TMEM115 |
| 28972 | SPCS1 | ENSG00000114902 | SPCS1 |
| 25871 | NEPRO | ENSG00000163608 | NEPRO |
| 55254 | TMEM39A | ENSG00000176142 | TMEM39A |
| 131601 | TPRA1 | ENSG00000163870 | TPRA1 |
| 7879 | RAB7A | ENSG00000075785 | RAB7A |
| 51122 | COMMD2 | ENSG00000114744 | COMMD2 |
| 64393 | ZMAT3 | ENSG00000172667 | ZMAT3 |
| 86 | ACTL6A | ENSG00000136518 | ACTL6A |
| 55486 | PARL | ENSG00000175193 | PARL |
| 90407 | TMEM41A | ENSG00000163900 | TMEM41A |
| 1487 | CTBP1 | ENSG00000159692 | CTBP1 |
| 7469 | NELFA | ENSG00000185049 | NELFA |
| 152 | ADRA2C | ENSG00000184160 | ADRA2C |
| 132789 | GNPDA2 | ENSG00000163281 | GNPDA2 |
| 10606 | PAICS | ENSG00000128050 | PAICS |
| 92597 | MOB1B | ENSG00000173542 | MOB1B |
| 266812 | NAP1L5 | ENSG00000177432 | NAP1L5 |
| 56916 | SMARCAD1 | ENSG00000163104 | SMARCAD1 |
| 55212 | BBS7 | ENSG00000138686 | BBS7 |
| 90826 | PRMT9 | ENSG00000164169 | PRMT9 |
| 4750 | NEK1 | ENSG00000137601 | NEK1 |
| 55100 | WDR70 | ENSG00000082068 | WDR70 |
| 55814 | BDP1 | ENSG00000274803 | BDP1 |
| 79810 | PTCD2 | ENSG00000049883 | PTCD2 |
| 167153 | TENT2 | ENSG00000164329 | TENT2 |
| 9765 | ZFYVE16 | ENSG00000039319 | ZFYVE16 |
| 55781 | RIOK2 | ENSG00000058729 | RIOK2 |
| 90355 | MACIR | ENSG00000181751 | MACIR |
| 153733 | CCDC112 | ENSG00000164221 | CCDC112 |
| 153443 | SRFBP1 | ENSG00000151304 | SRFBP1 |
| 8572 | PDLIM4 | ENSG00000131435 | PDLIM4 |
| 202052 | DNAJC18 | ENSG00000170464 | DNAJC18 |
| 23438 | HARS2 | ENSG00000112855 | HARS2 |
| 10826 | FAXDC2 | ENSG00000170271 | FAXDC2 |
| 9443 | MED7 | ENSG00000155868 | MED7 |
| 5917 | RARS1 | ENSG00000113643 | RARS1 |
| 80315 | CPEB4 | ENSG00000113742 | CPEB4 |
| 8899 | PRPF4B | ENSG00000112739 | PRPF4B |
| 10473 | HMGN4 | ENSG00000292175 | HMGN4 |
| 7746 | ZSCAN9 | ENSG00000137185 | ZSCAN9 |
| 8449 | DHX16 | ENSG00000233049 | DHX16 |
| 57827 | C6orf47 | ENSG00000228177 | C6orf47 |
| 578 | BAK1 | ENSG00000030110 | BAK1 |
| 5467 | PPARD | ENSG00000112033 | PPARD |
| 6428 | SRSF3 | ENSG00000112081 | SRSF3 |
| 9477 | MED20 | ENSG00000124641 | MED20 |
| 9533 | POLR1C | ENSG00000171453 | POLR1C |
| 26036 | ZNF451 | ENSG00000112200 | ZNF451 |
| 51715 | RAB23 | ENSG00000112210 | RAB23 |
| 25821 | MTO1 | ENSG00000135297 | MTO1 |
| 57226 | LYRM2 | ENSG00000083099 | LYRM2 |
| 23376 | UFL1 | ENSG00000014123 | UFL1 |
| 26235 | FBXL4 | ENSG00000112234 | FBXL4 |
| 91749 | MFSD4B | ENSG00000173214 | MFSD4B |
| 10758 | TRAF3IP2 | ENSG00000056972 | TRAF3IP2 |
| 5689 | PSMB1 | ENSG00000281184 | PSMB1 |
| 5575 | PRKAR1B | ENSG00000188191 | PRKAR1B |
| 90639 | COX19 | ENSG00000240230 | COX19 |
| 84262 | PSMG3 | ENSG00000157778 | PSMG3 |
| 8379 | MAD1L1 | ENSG00000002822 | MAD1L1 |
| 54476 | RNF216 | ENSG00000011275 | RNF216 |
| 221830 | POLR1F | ENSG00000105849 | POLR1F |
| 3364 | HUS1 | ENSG00000136273 | HUS1 |
| 55695 | NSUN5 | ENSG00000130305 | NSUN5 |
| 9569 | GTF2IRD1 | ENSG00000006704 | GTF2IRD1 |
| 113878 | DTX2 | ENSG00000282379 | DTX2 |
| 6717 | SRI | ENSG00000075142 | SRI |
| 9069 | CLDN12 | ENSG00000157224 | CLDN12 |
| 10898 | CPSF4 | ENSG00000160917 | CPSF4 |
| 3268 | AGFG2 | ENSG00000106351 | AGFG2 |
| 5001 | ORC5 | ENSG00000164815 | ORC5 |
| 60561 | RINT1 | ENSG00000135249 | RINT1 |
| 64418 | TMEM168 | ENSG00000146802 | TMEM168 |
| 27153 | ZNF777 | ENSG00000196453 | ZNF777 |
| 80346 | REEP4 | ENSG00000168476 | REEP4 |
| 5533 | PPP3CC | ENSG00000120910 | PPP3CC |
| 157313 | CDCA2 | ENSG00000184661 | CDCA2 |
| 23087 | TRIM35 | ENSG00000104228 | TRIM35 |
| 157574 | FBXO16 | ENSG00000214050 | FBXO16 |
| 7336 | UBE2V2 | ENSG00000169139 | UBE2V2 |
| 90362 | FAM110B | ENSG00000169122 | FAM110B |
| 55824 | PAG1 | ENSG00000076641 | PAG1 |
| 55656 | INTS8 | ENSG00000164941 | INTS8 |
| 51123 | ZNF706 | ENSG00000120963 | ZNF706 |
| 51105 | PHF20L1 | ENSG00000129292 | PHF20L1 |
| 203062 | TSNARE1 | ENSG00000171045 | TSNARE1 |
| 55958 | KLHL9 | ENSG00000198642 | KLHL9 |
| 54840 | APTX | ENSG00000137074 | APTX |
| 55035 | NOL8 | ENSG00000198000 | NOL8 |
| 10592 | SMC2 | ENSG00000136824 | SMC2 |
| 5998 | RGS3 | ENSG00000138835 | RGS3 |
| 51552 | RAB14 | ENSG00000119396 | RAB14 |
| 399665 | FAM102A | ENSG00000167106 | EEIG1 |
| 84885 | ZDHHC12 | ENSG00000160446 | ZDHHC12 |
| 5900 | RALGDS | ENSG00000160271 | RALGDS |
| 6837 | MED22 | ENSG00000281022 | MED22 |
| 57109 | REXO4 | ENSG00000280706 | REXO4 |
| 92715 | DPH7 | ENSG00000148399 | DPH7 |
| 23708 | GSPT2 | ENSG00000189369 | GSPT2 |
| 29934 | SNX12 | ENSG00000147164 | SNX12 |
| 139596 | UPRT | ENSG00000094841 | UPRT |
| 64860 | ARMCX5 | ENSG00000125962 | ARMCX5 |
| 644596 | SMIM10L2B | ENSG00000196972 | SMIM10L2B |
# saveRDS(Knowlesvarlist,"data/Knowlesvarlist.RDS")GO analysis of Highly Variable genes
I am using two backgrounds:
(1) the expressed background of the expressed genes in my data in the A
set (n = 14,084)
(2) the full EPI highly variable genes from my data in the B set (n =
508) set 2 or B did not yield anything! ##LIST KEGG Pathway genes for
HSV-1 #### A set
library(gprofiler2)
library(org.Hs.eg.db)
### This is for retrieving all genes annotated in the Herpes simplex virus list
# https://support.bioconductor.org/p/109871/
library(limma)
tab <- getGeneKEGGLinks(species="hsa")
tab$Symbol <- mapIds(org.Hs.eg.db, tab$GeneID,
column="SYMBOL", keytype="ENTREZID")
KEGG_05168 <- tab %>% dplyr::filter(PathwayID=="hsa05168")
# KEGG_05168 %>%
kable(list(KEGG_05168[1:171,], KEGG_05168[172:343,],KEGG_05168[344:512,]),
caption = "List of KEGG Herpes simplex KEGG pathway genes") %>%
kable_paper("striped", full_width = FALSE) %>%
kable_styling(
full_width = FALSE,
position = "left",
bootstrap_options = c("striped", "hover")
) %>%
scroll_box(width = "100%", height = "400px")
|
|
|
# backGL <-read_csv("data/backGL.txt",
# col_types = cols(...1 = col_skip()))
#
# SETA_resgenes <- gost(query = intersect_genes$SYMBOL,
# organism = "hsapiens",
# significant = FALSE,
# ordered_query = TRUE,
# domain_scope = "custom",
# measure_underrepresentation = FALSE,
# evcodes = TRUE,
# user_threshold = 0.05,
# correction_method = c("fdr"),
# custom_bg = backGL$SYMBOL,
# sources=c("GO:BP","KEGG"))
# saveRDS(SETA_resgenes,"data/DEG-GO/SETA_resgenes.RDS")
SETA_resgenes <- readRDS("data/DEG-GO/SETA_resgenes.RDS")
Set_A_genes <- gostplot(SETA_resgenes, capped = FALSE, interactive = TRUE)
Set_A_genessetA_table <- SETA_resgenes$result %>%
dplyr::select(c(source, term_id, term_name,intersection_size,intersection,
term_size, p_value))# %>%
list_intersect_path <- KEGG_05168 %>%
filter(Symbol%in% intersect_genes$SYMBOL)
list_intersect_path%>%
kable(., caption = "List of intersecting genes from the Herpes simplex KEGG pathway") %>%
kable_paper("striped", full_width = FALSE) %>%
kable_styling(
full_width = FALSE,
position = "left",
bootstrap_options = c("striped", "hover")
) %>%
scroll_box(width = "100%", height = "400px")| GeneID | PathwayID | Symbol |
|---|---|---|
| 100289635 | hsa05168 | ZNF605 |
| 10929 | hsa05168 | SRSF8 |
| 126070 | hsa05168 | ZNF440 |
| 146198 | hsa05168 | ZFP90 |
| 147657 | hsa05168 | ZNF480 |
| 147694 | hsa05168 | ZNF548 |
| 163087 | hsa05168 | ZNF383 |
| 22835 | hsa05168 | ZFP30 |
| 25799 | hsa05168 | ZNF324 |
| 27153 | hsa05168 | ZNF777 |
| 284323 | hsa05168 | ZNF780A |
| 29110 | hsa05168 | TBK1 |
| 51385 | hsa05168 | ZNF589 |
| 5371 | hsa05168 | PML |
| 5499 | hsa05168 | PPP1CA |
| 578 | hsa05168 | BAK1 |
| 6426 | hsa05168 | SRSF1 |
| 6428 | hsa05168 | SRSF3 |
| 7748 | hsa05168 | ZNF195 |
| 7769 | hsa05168 | ZNF226 |
| 7773 | hsa05168 | ZNF230 |
| 84503 | hsa05168 | ZNF527 |
| 93134 | hsa05168 | ZNF561 |
| 9668 | hsa05168 | ZNF432 |
setA_table %>%
kable(., caption = "List of GO BP and KEGG pathways enriched") %>%
kable_paper("striped", full_width = FALSE) %>%
kable_styling(
full_width = FALSE,
position = "left",
bootstrap_options = c("striped", "hover")
) %>%
scroll_box(width = "100%", height = "400px")| source | term_id | term_name | intersection_size | intersection | term_size | p_value |
|---|---|---|---|---|---|---|
| GO:BP | GO:0042770 | signal transduction in response to DNA damage | 10 | TIPRL,SDE2,ANKRD1,STK33,KAT5,RAD9A,CRY1,TRIAP1,KMT5A,PML | 180 | 0.0317931 |
| GO:BP | GO:0031848 | protection from non-homologous end joining at telomere | 3 | DCLRE1B,ERCC4,TERF2IP | 8 | 0.0953646 |
| GO:BP | GO:0051640 | organelle localization | 8 | PEX14,PLEKHM2,STX12,TRAPPC3,LMNA,PSEN2,BLOC1S2,BUB3 | 521 | 0.1059227 |
| GO:BP | GO:0009648 | photoperiodism | 3 | PPP1CA,CRY1,PML | 24 | 0.1059227 |
| GO:BP | GO:0032984 | protein-containing complex disassembly | 10 | PEX14,LIX1L,JMJD4,CCSAP,PPP1CA,NAV3,CHMP1A,PEX12,CHMP6,SH3GL1 | 219 | 0.1059227 |
| GO:BP | GO:0006367 | transcription initiation at RNA polymerase II promoter | 5 | MED8,POLR2G,MED17,CDK4,GTF2F2 | 95 | 0.1059227 |
| GO:BP | GO:0006368 | transcription elongation by RNA polymerase II | 10 | MED8,MED17,GTF2F2,HEXIM1,INTS2,MED15,NELFA,MED7,INTS8,MED22 | 109 | 0.1059227 |
| GO:BP | GO:0044774 | mitotic DNA integrity checkpoint signaling | 6 | SDE2,STK33,RAD9A,TRIAP1,PML,FZR1 | 84 | 0.1059227 |
| GO:BP | GO:0006383 | transcription by RNA polymerase III | 6 | SNAPC1,BRF1,RPTOR,GTF3C3,BDP1,POLR1C | 61 | 0.1059227 |
| GO:BP | GO:0044773 | mitotic DNA damage checkpoint signaling | 6 | SDE2,STK33,RAD9A,TRIAP1,PML,FZR1 | 80 | 0.1059227 |
| GO:BP | GO:1902455 | negative regulation of stem cell population maintenance | 3 | HDAC1,BRMS1,ING1 | 21 | 0.1059227 |
| GO:BP | GO:0044721 | protein import into peroxisome matrix, substrate release | 2 | PEX14,PEX12 | 5 | 0.1059227 |
| GO:BP | GO:1902459 | positive regulation of stem cell population maintenance | 5 | HDAC1,BRMS1,ING1,SMARCB1,ACTL6A | 45 | 0.1059227 |
| GO:BP | GO:0015786 | UDP-glucose transmembrane transport | 2 | SLC35B1,SLC35C2 | 3 | 0.1059227 |
| GO:BP | GO:0033043 | regulation of organelle organization | 22 | WRAP73,CPLANE2,ARHGEF10L,ASAP3,LMNA,CCSAP,PPP3CB,SYNPO2L,BUB3,ARFIP2,KAT5,RBM14,ARAP1,NAV3,TRIAP1,LIG4,TTC8,PML,ERCC4,TERF2IP,CHMP1A,PAFAH1B1 | 1002 | 0.1059227 |
| GO:BP | GO:0030038 | contractile actin filament bundle assembly | 2 | ARHGEF10L,ASAP3 | 95 | 0.1059227 |
| GO:BP | GO:0033133 | positive regulation of glucokinase activity | 2 | DUSP12,RANBP2 | 4 | 0.1059227 |
| GO:BP | GO:0006481 | C-terminal protein methylation | 1 | ICMT | 2 | 0.1059227 |
| GO:BP | GO:0110020 | regulation of actomyosin structure organization | 2 | ARHGEF10L,ASAP3 | 90 | 0.1059227 |
| GO:BP | GO:0090201 | negative regulation of release of cytochrome c from mitochondria | 4 | LMNA,TRIAP1,PARL,BAK1 | 17 | 0.1059227 |
| GO:BP | GO:0001666 | response to hypoxia | 5 | AGTRAP,LMNA,ADORA1,PSEN2,SUV39H2 | 235 | 0.1059227 |
| GO:BP | GO:0042323 | negative regulation of circadian sleep/wake cycle, non-REM sleep | 1 | ADORA1 | 1 | 0.1059227 |
| GO:BP | GO:0070897 | transcription preinitiation complex assembly | 8 | MED8,MED17,BRF1,MED15,SMARCB1,BDP1,MED7,MED22 | 66 | 0.1059227 |
| GO:BP | GO:0043967 | histone H4 acetylation | 5 | VPS72,KAT5,PHF20,ACTL6A,CTBP1 | 42 | 0.1059227 |
| GO:BP | GO:0016233 | telomere capping | 4 | DCLRE1B,ERCC4,TERF2IP,MAP2K7 | 34 | 0.1059227 |
| GO:BP | GO:0016236 | macroautophagy | 18 | STX12,LIX1L,ARFIP2,VPS37C,PAFAH1B2,EI24,TBK1,CRY1,WDR24,CHMP1A,CHMP6,RAB1A,STAM2,NSFL1C,TMEM39A,RAB7A,RAB23,UFL1 | 308 | 0.1059227 |
| GO:BP | GO:0036258 | multivesicular body assembly | 4 | VPS37C,CHMP1A,CHMP6,STAM2 | 32 | 0.1059227 |
| GO:BP | GO:0036257 | multivesicular body organization | 4 | VPS37C,CHMP1A,CHMP6,STAM2 | 33 | 0.1059227 |
| GO:BP | GO:1902855 | regulation of non-motile cilium assembly | 1 | WRAP73 | 9 | 0.1059227 |
| GO:BP | GO:0009649 | entrainment of circadian clock | 3 | PPP1CA,CRY1,PML | 26 | 0.1059227 |
| GO:BP | GO:2001252 | positive regulation of chromosome organization | 9 | KAT5,LIG4,PML,TERF2IP,MAP2K7,INO80D,ACTL6A,MAD1L1,SMC2 | 103 | 0.1059227 |
| GO:BP | GO:0006354 | DNA-templated transcription elongation | 11 | MED8,MED17,GTF2F2,TEFM,HEXIM1,INTS2,MED15,NELFA,MED7,INTS8,MED22 | 125 | 0.1059227 |
| GO:BP | GO:0006352 | DNA-templated transcription initiation | 13 | MED8,POLR2G,MED17,CDK4,GTF2F2,BRF1,MED15,SMARCB1,BDP1,MED7,ZNF451,POLR1F,MED22 | 131 | 0.1059227 |
| GO:BP | GO:0002674 | negative regulation of acute inflammatory response | 2 | ADORA1,GSTP1 | 6 | 0.1059227 |
| GO:BP | GO:0048144 | fibroblast proliferation | 6 | ECD,GSTP1,CDK4,LIG4,PML,INCA1 | 89 | 0.1059227 |
| GO:BP | GO:0048145 | regulation of fibroblast proliferation | 5 | GSTP1,CDK4,LIG4,PML,INCA1 | 75 | 0.1059227 |
| GO:BP | GO:0032231 | regulation of actin filament bundle assembly | 2 | ARHGEF10L,ASAP3 | 90 | 0.1059227 |
| GO:BP | GO:0031570 | DNA integrity checkpoint signaling | 7 | TIPRL,SDE2,STK33,RAD9A,CRY1,TRIAP1,PML | 130 | 0.1059227 |
| GO:BP | GO:1901987 | regulation of cell cycle phase transition | 21 | TIPRL,SDE2,ECD,BUB3,STK33,RAD9A,CDK4,CRY1,TRIAP1,PML,RPTOR,FZR1,MTA3,SMARCB1,TPRA1,ACTL6A,RIOK2,UFL1,MAD1L1,HUS1,RINT1 | 387 | 0.1059227 |
| GO:BP | GO:1901988 | negative regulation of cell cycle phase transition | 8 | TIPRL,SDE2,BUB3,STK33,RAD9A,CRY1,TRIAP1,PML | 234 | 0.1059227 |
| GO:BP | GO:0046499 | S-adenosylmethioninamine metabolic process | 1 | ICMT | 1 | 0.1059227 |
| GO:BP | GO:0046498 | S-adenosylhomocysteine metabolic process | 1 | ICMT | 2 | 0.1059227 |
| GO:BP | GO:0032244 | positive regulation of nucleoside transport | 1 | ADORA1 | 1 | 0.1059227 |
| GO:BP | GO:0061919 | process utilizing autophagic mechanism | 24 | STX12,LIX1L,ARFIP2,VPS37C,KAT5,PAFAH1B2,EI24,TBK1,CRY1,WDR24,ERCC4,CHMP1A,OSBPL7,RPTOR,CHMP6,RAB1A,STAM2,NSFL1C,TMEM39A,RAB7A,PARL,RAB23,UFL1,FBXL4 | 516 | 0.1059227 |
| GO:BP | GO:0007093 | mitotic cell cycle checkpoint signaling | 6 | SDE2,BUB3,STK33,RAD9A,TRIAP1,PML | 137 | 0.1059227 |
| GO:BP | GO:0007346 | regulation of mitotic cell cycle | 23 | SDE2,ECD,BUB3,STK33,RAD9A,CDK4,TRIAP1,PML,PAFAH1B1,NLE1,RPS6KB1,RPTOR,FZR1,MTA3,SMARCB1,TPRA1,ACTL6A,RIOK2,MAD1L1,HUS1,RINT1,CDCA2,TRIM35 | 438 | 0.1059227 |
| GO:BP | GO:0061956 | penetration of cumulus oophorus | 1 | PITHD1 | 1 | 0.1059227 |
| GO:BP | GO:0010453 | regulation of cell fate commitment | 2 | HDAC1,LMO4 | 26 | 0.1059227 |
| GO:BP | GO:0003274 | endocardial cushion fusion | 1 | CPLANE2 | 5 | 0.1059227 |
| GO:BP | GO:0010948 | negative regulation of cell cycle process | 9 | TIPRL,SDE2,BUB3,STK33,RBM14,RAD9A,CRY1,TRIAP1,PML | 271 | 0.1059227 |
| GO:BP | GO:0062232 | prostanoid catabolic process | 1 | LYPLA2 | 2 | 0.1059227 |
| GO:BP | GO:0036293 | response to decreased oxygen levels | 5 | AGTRAP,LMNA,ADORA1,PSEN2,SUV39H2 | 248 | 0.1059227 |
| GO:BP | GO:0045786 | negative regulation of cell cycle | 12 | TIPRL,SDE2,BUB3,STK33,RBM14,RAD9A,CRY1,TRIAP1,PML,INCA1,NLE1,HEXIM1 | 337 | 0.1059227 |
| GO:BP | GO:0045724 | positive regulation of cilium assembly | 1 | WRAP73 | 25 | 0.1059227 |
| GO:BP | GO:0032784 | regulation of DNA-templated transcription elongation | 9 | MED8,MED17,HEXIM1,INTS2,MED15,NELFA,MED7,INTS8,MED22 | 99 | 0.1059227 |
| GO:BP | GO:0060260 | regulation of transcription initiation by RNA polymerase II | 7 | MED8,MED17,CDK4,MED15,MED7,ZNF451,MED22 | 70 | 0.1059227 |
| GO:BP | GO:0098732 | macromolecule deacylation | 8 | LYPLA2,HDAC1,BRMS1,ABHD13,PML,MIER2,MTA3,CTBP1 | 92 | 0.1059227 |
| GO:BP | GO:0070482 | response to oxygen levels | 5 | AGTRAP,LMNA,ADORA1,PSEN2,SUV39H2 | 271 | 0.1059227 |
| GO:BP | GO:0006302 | double-strand break repair | 15 | DCLRE1B,VPS72,DCLRE1A,KAT5,KMT5A,LIG4,PML,ERCC4,TERF2IP,PIAS4,PSMD14,AP5S1,SMARCB1,ACTL6A,SMARCAD1 | 278 | 0.1059227 |
| GO:BP | GO:0032900 | negative regulation of neurotrophin production | 1 | ADORA1 | 1 | 0.1059227 |
| GO:BP | GO:1902857 | positive regulation of non-motile cilium assembly | 1 | WRAP73 | 7 | 0.1059227 |
| GO:BP | GO:0034243 | regulation of transcription elongation by RNA polymerase II | 9 | MED8,MED17,HEXIM1,INTS2,MED15,NELFA,MED7,INTS8,MED22 | 85 | 0.1059227 |
| GO:BP | GO:0030330 | DNA damage response, signal transduction by p53 class mediator | 5 | ANKRD1,KAT5,TRIAP1,KMT5A,PML | 70 | 0.1059227 |
| GO:BP | GO:0036250 | peroxisome transport along microtubule | 1 | PEX14 | 1 | 0.1059227 |
| GO:BP | GO:0043149 | stress fiber assembly | 2 | ARHGEF10L,ASAP3 | 95 | 0.1059227 |
| GO:BP | GO:1905344 | prostaglandin catabolic process | 1 | LYPLA2 | 2 | 0.1059227 |
| GO:BP | GO:0043153 | entrainment of circadian clock by photoperiod | 3 | PPP1CA,CRY1,PML | 23 | 0.1059227 |
| GO:BP | GO:0043558 | regulation of translational initiation in response to stress | 3 | PPP1CA,PML,IMPACT | 16 | 0.1059227 |
| GO:BP | GO:0043247 | telomere maintenance in response to DNA damage | 5 | DCLRE1B,ERCC4,TERF2IP,INO80D,ACTL6A | 27 | 0.1059227 |
| GO:BP | GO:0000075 | cell cycle checkpoint signaling | 8 | TIPRL,SDE2,BUB3,STK33,RAD9A,CRY1,TRIAP1,PML | 184 | 0.1059227 |
| GO:BP | GO:1903047 | mitotic cell cycle process | 33 | WRAP73,SDE2,CCSAP,ECD,BUB3,STK33,KAT5,RAD9A,CDK4,TRIAP1,KMT5A,RAN,PML,E2F4,CHMP1A,PAFAH1B1,RPS6KB1,RPTOR,CHMP6,FZR1,ZNF324,MTA3,NSFL1C,SMARCB1,TPRA1,ACTL6A,RIOK2,MAD1L1,HUS1,RINT1,REEP4,CDCA2,SMC2 | 690 | 0.1059227 |
| GO:BP | GO:0000070 | mitotic sister chromatid segregation | 8 | WRAP73,CCSAP,BUB3,KAT5,KMT5A,RAN,CHMP1A,CHMP6 | 178 | 0.1059227 |
| GO:BP | GO:0035601 | protein deacylation | 8 | LYPLA2,HDAC1,BRMS1,ABHD13,PML,MIER2,MTA3,CTBP1 | 91 | 0.1059227 |
| GO:BP | GO:0006914 | autophagy | 24 | STX12,LIX1L,ARFIP2,VPS37C,KAT5,PAFAH1B2,EI24,TBK1,CRY1,WDR24,ERCC4,CHMP1A,OSBPL7,RPTOR,CHMP6,RAB1A,STAM2,NSFL1C,TMEM39A,RAB7A,PARL,RAB23,UFL1,FBXL4 | 516 | 0.1059227 |
| GO:BP | GO:0016575 | histone deacetylation | 6 | HDAC1,BRMS1,PML,MIER2,MTA3,CTBP1 | 62 | 0.1059227 |
| GO:BP | GO:0042659 | regulation of cell fate specification | 2 | HDAC1,LMO4 | 23 | 0.1059227 |
| GO:BP | GO:0000077 | DNA damage checkpoint signaling | 7 | TIPRL,SDE2,STK33,RAD9A,CRY1,TRIAP1,PML | 121 | 0.1059227 |
| GO:BP | GO:0007032 | endosome organization | 7 | VPS37C,AQP11,CHMP1A,CHMP6,STAM2,ARFGEF2,RAB7A | 93 | 0.1059227 |
| GO:BP | GO:0016560 | protein import into peroxisome matrix, docking | 1 | PEX14 | 3 | 0.1059227 |
| GO:BP | GO:0016561 | protein import into peroxisome matrix, translocation | 1 | PEX14 | 4 | 0.1059227 |
| GO:BP | GO:0007623 | circadian rhythm | 7 | HDAC1,ADORA1,SUV39H2,KAT5,PPP1CA,CRY1,PML | 158 | 0.1059227 |
| GO:BP | GO:0000226 | microtubule cytoskeleton organization | 3 | WRAP73,PEX14,CPLANE2 | 551 | 0.1059227 |
| GO:BP | GO:0019068 | virion assembly | 5 | VPS37C,CHMP1A,CHMP6,RAB1A,SPCS1 | 33 | 0.1059227 |
| GO:BP | GO:0006998 | nuclear envelope organization | 6 | LMNA,CHMP1A,PAFAH1B1,CHMP6,NSFL1C,REEP4 | 54 | 0.1059227 |
| GO:BP | GO:0018410 | C-terminal protein amino acid modification | 1 | ICMT | 10 | 0.1059227 |
| GO:BP | GO:0051492 | regulation of stress fiber assembly | 5 | ARHGEF10L,ASAP3,SYNPO2L,ARAP1,TTC8 | 81 | 0.1059227 |
| GO:BP | GO:0007010 | cytoskeleton organization | 5 | WRAP73,PEX14,CPLANE2,ARHGEF10L,ASAP3 | 1188 | 0.1059227 |
| GO:BP | GO:0048264 | determination of ventral identity | 1 | AIDA | 1 | 0.1061980 |
| GO:BP | GO:0010569 | regulation of double-strand break repair via homologous recombination | 5 | VPS72,KAT5,KMT5A,TERF2IP,PIAS4 | 64 | 0.1061980 |
| GO:BP | GO:0006974 | DNA damage response | 18 | DCLRE1B,VPS72,TIPRL,SDE2,ANKRD1,DCLRE1A,STK33,SPINDOC,KAT5,RAD9A,EMSY,CRY1,TRIAP1,KMT5A,LIG4,PML,ERCC4,TERF2IP | 798 | 0.1061980 |
| GO:BP | GO:0042754 | negative regulation of circadian rhythm | 2 | ADORA1,CRY1 | 8 | 0.1069357 |
| GO:BP | GO:0044770 | cell cycle phase transition | 24 | TIPRL,SDE2,ECD,BUB3,STK33,RAD9A,CDK4,CRY1,TRIAP1,PML,E2F4,RPS6KB1,RPTOR,FZR1,ZNF324,MTA3,SMARCB1,TPRA1,ACTL6A,RIOK2,UFL1,MAD1L1,HUS1,RINT1 | 496 | 0.1069357 |
| GO:BP | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage | 2 | RAD9A,PIAS4 | 7 | 0.1069357 |
| GO:BP | GO:0045324 | late endosome to vacuole transport | 4 | VPS37C,CHMP1A,CHMP6,STAM2 | 36 | 0.1069357 |
| GO:BP | GO:0002084 | protein depalmitoylation | 2 | LYPLA2,ABHD13 | 10 | 0.1069357 |
| GO:BP | GO:1903251 | multi-ciliated epithelial cell differentiation | 2 | TTC8,E2F4 | 6 | 0.1069357 |
| GO:BP | GO:0032922 | circadian regulation of gene expression | 4 | HDAC1,PPP1CA,CRY1,PML | 61 | 0.1069357 |
| GO:BP | GO:0002228 | natural killer cell mediated immunity | 2 | PLEKHM2,RNF19B | 34 | 0.1069357 |
| GO:BP | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | 4 | VPS37C,CHMP1A,CHMP6,STAM2 | 35 | 0.1069357 |
| GO:BP | GO:0098734 | macromolecule depalmitoylation | 2 | LYPLA2,ABHD13 | 11 | 0.1069357 |
| GO:BP | GO:0044819 | mitotic G1/S transition checkpoint signaling | 3 | SDE2,TRIAP1,PML | 30 | 0.1069357 |
| GO:BP | GO:0055001 | muscle cell development | 4 | LMNA,PPP3CB,SYNPO2L,ANKRD1 | 166 | 0.1069357 |
| GO:BP | GO:0006303 | double-strand break repair via nonhomologous end joining | 4 | DCLRE1B,DCLRE1A,LIG4,ERCC4 | 62 | 0.1069357 |
| GO:BP | GO:0042752 | regulation of circadian rhythm | 5 | ADORA1,KAT5,PPP1CA,CRY1,PML | 91 | 0.1069357 |
| GO:BP | GO:0000301 | retrograde transport, vesicle recycling within Golgi | 2 | COG2,COG7 | 9 | 0.1069357 |
| GO:BP | GO:0042267 | natural killer cell mediated cytotoxicity | 2 | PLEKHM2,RNF19B | 34 | 0.1069357 |
| GO:BP | GO:1901673 | regulation of mitotic spindle assembly | 3 | CCSAP,CHMP1A,CHMP6 | 23 | 0.1069357 |
| GO:BP | GO:1990755 | mitotic spindle microtubule depolymerization | 1 | CCSAP | 1 | 0.1069357 |
| GO:BP | GO:0061572 | actin filament bundle organization | 2 | ARHGEF10L,ASAP3 | 138 | 0.1069357 |
| GO:BP | GO:0016050 | vesicle organization | 16 | CPLANE2,STX12,TRAPPC3,BLOC1S2,VPS37C,AQP11,CHMP1A,PAFAH1B1,SNX11,CHMP6,AP1M1,RAB1A,STAM2,ARFGEF2,RAB7A,ZFYVE16 | 317 | 0.1069357 |
| GO:BP | GO:0051053 | negative regulation of DNA metabolic process | 6 | ANKRD1,KAT5,KMT5A,PML,ERCC4,TERF2IP | 117 | 0.1069357 |
| GO:BP | GO:0039702 | viral budding via host ESCRT complex | 3 | VPS37C,CHMP1A,CHMP6 | 21 | 0.1069357 |
| GO:BP | GO:0006446 | regulation of translational initiation | 5 | POLR2G,PPP1CA,PML,RPS6KB1,IMPACT | 72 | 0.1069357 |
| GO:BP | GO:0007049 | cell cycle | 36 | WRAP73,VPS72,LMNA,TIPRL,SDE2,CCSAP,SUV39H2,ECD,DCLRE1A,BUB3,STK33,KAT5,RBM14,RAD9A,PPP1CA,CDK4,CRY1,TRIAP1,KMT5A,RAN,LIG4,ING1,PML,ERCC4,E2F4,CHMP1A,PAFAH1B1,INCA1,NLE1,HEXIM1,PRR11,RPS6KB1,RPTOR,CHMP6,RIOK3,FZR1 | 1516 | 0.1069357 |
| GO:BP | GO:0051017 | actin filament bundle assembly | 2 | ARHGEF10L,ASAP3 | 136 | 0.1069357 |
| GO:BP | GO:0051726 | regulation of cell cycle | 43 | VPS72,TIPRL,SDE2,CCSAP,ECD,BUB3,STK33,KAT5,RBM14,RAD9A,CDK4,CRY1,TRIAP1,PML,CHMP1A,PAFAH1B1,INCA1,NLE1,HEXIM1,PRR11,RPS6KB1,RPTOR,CHMP6,FZR1,SERTAD1,MTA3,INO80D,NSFL1C,SMARCB1,TPRA1,ACTL6A,CTBP1,RIOK2,PRPF4B,BAK1,UFL1,MAD1L1,HUS1,RINT1,CDCA2,TRIM35,KLHL9,SMC2 | 940 | 0.1069357 |
| GO:BP | GO:0046128 | purine ribonucleoside metabolic process | 1 | ICMT | 16 | 0.1069357 |
| GO:BP | GO:0016072 | rRNA metabolic process | 15 | NSUN4,SDE2,NPM3,BRF1,UTP6,EIF4A3,RIOK3,TRMT61B,GTF3C3,SMARCB1,RIOK2,SRFBP1,NSUN5,NOL8,REXO4 | 252 | 0.1069357 |
| GO:BP | GO:0061343 | cell adhesion involved in heart morphogenesis | 1 | CPLANE2 | 6 | 0.1069357 |
| GO:BP | GO:0016558 | protein import into peroxisome matrix | 1 | PEX14 | 14 | 0.1069357 |
| GO:BP | GO:0061198 | fungiform papilla formation | 1 | HDAC1 | 3 | 0.1069357 |
| GO:BP | GO:0031571 | mitotic G1 DNA damage checkpoint signaling | 3 | SDE2,TRIAP1,PML | 30 | 0.1069357 |
| GO:BP | GO:0070933 | histone H4 deacetylation | 1 | HDAC1 | 3 | 0.1069357 |
| GO:BP | GO:0031627 | telomeric loop formation | 1 | DCLRE1B | 2 | 0.1069357 |
| GO:BP | GO:0043508 | negative regulation of JUN kinase activity | 2 | AIDA,GSTP1 | 13 | 0.1069357 |
| GO:BP | GO:0043555 | regulation of translation in response to stress | 3 | PPP1CA,PML,IMPACT | 24 | 0.1069357 |
| GO:BP | GO:1903301 | positive regulation of hexokinase activity | 2 | DUSP12,RANBP2 | 5 | 0.1070583 |
| GO:BP | GO:2001233 | regulation of apoptotic signaling pathway | 12 | HDAC1,LMNA,BDNF,RAD9A,PPP1CA,GSTP1,TRIAP1,PML,INCA1,NLE1,RPS6KB1,PIAS4 | 319 | 0.1081479 |
| GO:BP | GO:0046755 | viral budding | 3 | VPS37C,CHMP1A,CHMP6 | 24 | 0.1081479 |
| GO:BP | GO:0031468 | nuclear membrane reassembly | 4 | CHMP1A,CHMP6,NSFL1C,REEP4 | 25 | 0.1081479 |
| GO:BP | GO:0019827 | stem cell population maintenance | 6 | HDAC1,VPS72,BRMS1,MED17,LIG4,ING1 | 151 | 0.1081479 |
| GO:BP | GO:0045930 | negative regulation of mitotic cell cycle | 13 | SDE2,BUB3,STK33,RAD9A,TRIAP1,PML,NLE1,FZR1,TPRA1,MAD1L1,HUS1,RINT1,TRIM35 | 209 | 0.1081479 |
| GO:BP | GO:0022411 | cellular component disassembly | 19 | PEX14,LIX1L,JMJD4,CCSAP,ARFIP2,KAT5,PPP1CA,NAV3,TRIP4,CHMP1A,PAFAH1B1,PEX12,CHMP6,SH3GL1,BLCAP,SMARCB1,ASCC2,TMEM39A,PARL | 429 | 0.1081479 |
| GO:BP | GO:0042278 | purine nucleoside metabolic process | 1 | ICMT | 20 | 0.1081479 |
| GO:BP | GO:0032509 | endosome transport via multivesicular body sorting pathway | 4 | VPS37C,CHMP1A,CHMP6,STAM2 | 41 | 0.1082602 |
| GO:BP | GO:0045815 | transcription initiation-coupled chromatin remodeling | 4 | VPS72,RBM14,N6AMT1,SMARCB1 | 35 | 0.1088100 |
| GO:BP | GO:0006996 | organelle organization | 6 | WRAP73,PEX14,PLEKHM2,CPLANE2,ARHGEF10L,ASAP3 | 2976 | 0.1088100 |
| GO:BP | GO:0010564 | regulation of cell cycle process | 30 | TIPRL,SDE2,CCSAP,ECD,BUB3,STK33,KAT5,RBM14,RAD9A,CDK4,CRY1,TRIAP1,PML,CHMP1A,RPTOR,CHMP6,FZR1,MTA3,NSFL1C,SMARCB1,TPRA1,ACTL6A,RIOK2,UFL1,MAD1L1,HUS1,RINT1,CDCA2,KLHL9,SMC2 | 622 | 0.1088100 |
| GO:BP | GO:0072663 | establishment of protein localization to peroxisome | 1 | PEX14 | 19 | 0.1088100 |
| GO:BP | GO:2000779 | regulation of double-strand break repair | 8 | VPS72,KAT5,KMT5A,PML,TERF2IP,PIAS4,SMARCB1,ACTL6A | 123 | 0.1088100 |
| GO:BP | GO:1902017 | regulation of cilium assembly | 1 | WRAP73 | 55 | 0.1088100 |
| GO:BP | GO:0010833 | telomere maintenance via telomere lengthening | 5 | DCLRE1B,PML,ERCC4,TERF2IP,MAP2K7 | 74 | 0.1088100 |
| GO:BP | GO:2000142 | regulation of DNA-templated transcription initiation | 7 | MED8,MED17,CDK4,MED15,MED7,ZNF451,MED22 | 77 | 0.1088100 |
| GO:BP | GO:1901798 | positive regulation of signal transduction by p53 class mediator | 3 | ANKRD1,PML,HEXIM1 | 28 | 0.1088100 |
| GO:BP | GO:0045814 | negative regulation of gene expression, epigenetic | 3 | HDAC1,LMNA,SUV39H2 | 94 | 0.1088100 |
| GO:BP | GO:0032242 | regulation of nucleoside transport | 1 | ADORA1 | 2 | 0.1088100 |
| GO:BP | GO:0072662 | protein localization to peroxisome | 1 | PEX14 | 19 | 0.1088100 |
| GO:BP | GO:0097190 | apoptotic signaling pathway | 14 | HDAC1,LMNA,ADORA1,BLOC1S2,BDNF,RAD9A,PPP1CA,GSTP1,TRIAP1,DIABLO,GSKIP,PML,INCA1,NLE1 | 505 | 0.1088100 |
| GO:BP | GO:0031032 | actomyosin structure organization | 5 | ARHGEF10L,ASAP3,SYNPO2L,ANKRD1,ARAP1 | 187 | 0.1088100 |
| GO:BP | GO:0032204 | regulation of telomere maintenance | 7 | LMNA,PML,ERCC4,TERF2IP,MAP2K7,INO80D,ACTL6A | 97 | 0.1088100 |
| GO:BP | GO:0009303 | rRNA transcription | 4 | NPM3,BRF1,GTF3C3,SMARCB1 | 37 | 0.1088100 |
| GO:BP | GO:0006605 | protein targeting | 2 | ICMT,PEX14 | 312 | 0.1088100 |
| GO:BP | GO:0038166 | angiotensin-activated signaling pathway | 1 | AGTRAP | 10 | 0.1088100 |
| GO:BP | GO:0043968 | histone H2A acetylation | 2 | VPS72,KAT5 | 21 | 0.1088100 |
| GO:BP | GO:0090174 | organelle membrane fusion | 2 | CPLANE2,STX12 | 103 | 0.1088100 |
| GO:BP | GO:1902850 | microtubule cytoskeleton organization involved in mitosis | 7 | WRAP73,CCSAP,KAT5,RAN,CHMP1A,PAFAH1B1,CHMP6 | 158 | 0.1088100 |
| GO:BP | GO:1990116 | ribosome-associated ubiquitin-dependent protein catabolic process | 2 | TRIP4,ASCC2 | 6 | 0.1088100 |
| GO:BP | GO:0090148 | membrane fission | 4 | VPS37C,CHMP1A,CHMP6,STAM2 | 43 | 0.1088100 |
| GO:BP | GO:0033044 | regulation of chromosome organization | 14 | LMNA,BUB3,KAT5,LIG4,PML,ERCC4,TERF2IP,MAP2K7,INO80D,SMARCB1,ACTL6A,RIOK2,MAD1L1,SMC2 | 236 | 0.1088100 |
| GO:BP | GO:0006625 | protein targeting to peroxisome | 1 | PEX14 | 19 | 0.1088100 |
| GO:BP | GO:0071763 | nuclear membrane organization | 5 | CHMP1A,PAFAH1B1,CHMP6,NSFL1C,REEP4 | 43 | 0.1088100 |
| GO:BP | GO:0040029 | epigenetic regulation of gene expression | 4 | HDAC1,VPS72,LMNA,SUV39H2 | 182 | 0.1088100 |
| GO:BP | GO:0006884 | cell volume homeostasis | 3 | AQP11,E2F4,SLC12A4 | 25 | 0.1088100 |
| GO:BP | GO:0006906 | vesicle fusion | 2 | CPLANE2,STX12 | 101 | 0.1088100 |
| GO:BP | GO:0070256 | negative regulation of mucus secretion | 1 | ADORA1 | 2 | 0.1088100 |
| GO:BP | GO:1990683 | DNA double-strand break attachment to nuclear envelope | 1 | LMNA | 2 | 0.1088100 |
| GO:BP | GO:0032899 | regulation of neurotrophin production | 1 | ADORA1 | 2 | 0.1088100 |
| GO:BP | GO:0098727 | maintenance of cell number | 6 | HDAC1,VPS72,BRMS1,MED17,LIG4,ING1 | 153 | 0.1088100 |
| GO:BP | GO:0006891 | intra-Golgi vesicle-mediated transport | 3 | TRAPPC3,COG2,COG7 | 33 | 0.1088100 |
| GO:BP | GO:1905515 | non-motile cilium assembly | 1 | WRAP73 | 56 | 0.1095617 |
| GO:BP | GO:0006413 | translational initiation | 6 | POLR2G,PPP1CA,BRF1,PML,RPS6KB1,IMPACT | 113 | 0.1095617 |
| GO:BP | GO:0002339 | B cell selection | 2 | BAK1,TRAF3IP2 | 4 | 0.1095617 |
| GO:BP | GO:0000278 | mitotic cell cycle | 21 | WRAP73,SDE2,CCSAP,ECD,BUB3,STK33,KAT5,RAD9A,CDK4,TRIAP1,KMT5A,RAN,PML,E2F4,CHMP1A,PAFAH1B1,NLE1,RPS6KB1,RPTOR,CHMP6,FZR1 | 816 | 0.1095617 |
| GO:BP | GO:0009119 | ribonucleoside metabolic process | 1 | ICMT | 23 | 0.1095617 |
| GO:BP | GO:0061197 | fungiform papilla morphogenesis | 1 | HDAC1 | 4 | 0.1095617 |
| GO:BP | GO:0015919 | peroxisomal membrane transport | 1 | PEX14 | 20 | 0.1095617 |
| GO:BP | GO:0034660 | ncRNA metabolic process | 27 | NSUN4,SDE2,NPM3,CLP1,SNAPC1,BRF1,UTP6,INTS2,EIF4A3,RIOK3,FARSA,TRMT61B,METTL8,GTF3C3,SMARCB1,TENT2,RIOK2,SRFBP1,HARS2,RARS1,PPARD,SRSF3,MTO1,NSUN5,INTS8,NOL8,REXO4 | 562 | 0.1095617 |
| GO:BP | GO:0000082 | G1/S transition of mitotic cell cycle | 11 | SDE2,ECD,CDK4,TRIAP1,PML,E2F4,RPS6KB1,RPTOR,ZNF324,SMARCB1,ACTL6A | 206 | 0.1095617 |
| GO:BP | GO:0007017 | microtubule-based process | 3 | WRAP73,PEX14,CPLANE2 | 759 | 0.1095962 |
| GO:BP | GO:0035732 | nitric oxide storage | 1 | GSTP1 | 1 | 0.1095962 |
| GO:BP | GO:0110097 | regulation of calcium import into the mitochondrion | 1 | PSEN2 | 2 | 0.1095962 |
| GO:BP | GO:0000819 | sister chromatid segregation | 13 | WRAP73,CCSAP,BUB3,KAT5,KMT5A,RAN,CHMP1A,CHMP6,SMARCB1,ACTL6A,RIOK2,MAD1L1,SMC2 | 217 | 0.1095962 |
| GO:BP | GO:1901620 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | 1 | CPLANE2 | 12 | 0.1095962 |
| GO:BP | GO:2000273 | positive regulation of signaling receptor activity | 2 | HDAC1,ADORA1 | 33 | 0.1095962 |
| GO:BP | GO:0071478 | cellular response to radiation | 6 | SDE2,RAD9A,CRY1,TRIAP1,LIG4,ERCC4 | 149 | 0.1095962 |
| GO:BP | GO:0090307 | mitotic spindle assembly | 1 | WRAP73 | 69 | 0.1109746 |
| GO:BP | GO:0043574 | peroxisomal transport | 1 | PEX14 | 22 | 0.1116155 |
| GO:BP | GO:0032205 | negative regulation of telomere maintenance | 3 | PML,ERCC4,TERF2IP | 34 | 0.1116155 |
| GO:BP | GO:0016311 | dephosphorylation | 5 | DUSP12,TIPRL,ADORA1,PPP3CB,FRA10AC1 | 278 | 0.1116155 |
| GO:BP | GO:1905949 | negative regulation of calcium ion import across plasma membrane | 2 | PPP3CB,PPP3CC | 4 | 0.1116155 |
| GO:BP | GO:0036297 | interstrand cross-link repair | 3 | DCLRE1B,DCLRE1A,ERCC4 | 36 | 0.1116155 |
| GO:BP | GO:1904505 | regulation of telomere maintenance in response to DNA damage | 3 | ERCC4,INO80D,ACTL6A | 17 | 0.1116155 |
| GO:BP | GO:1905168 | positive regulation of double-strand break repair via homologous recombination | 4 | VPS72,KAT5,PIAS4,ACTL6A | 33 | 0.1116155 |
| GO:BP | GO:0034453 | microtubule anchoring | 1 | PEX14 | 24 | 0.1119508 |
| GO:BP | GO:0033554 | cellular response to stress | 19 | PEX14,ARHGEF10L,DCLRE1B,VPS72,LMNA,TIPRL,AIDA,SDE2,SUV39H2,ANKRD1,DCLRE1A,STK33,SPINDOC,KAT5,RAD9A,PPP1CA,GSTP1,EMSY,AQP11 | 1663 | 0.1137087 |
| GO:BP | GO:1901990 | regulation of mitotic cell cycle phase transition | 16 | SDE2,ECD,BUB3,CDK4,TRIAP1,PML,RPTOR,FZR1,MTA3,SMARCB1,TPRA1,ACTL6A,RIOK2,MAD1L1,HUS1,RINT1 | 305 | 0.1137087 |
| GO:BP | GO:0014041 | regulation of neuron maturation | 2 | RAC3,BCL11A | 6 | 0.1145916 |
| GO:BP | GO:1902117 | positive regulation of organelle assembly | 1 | WRAP73 | 75 | 0.1145916 |
| GO:BP | GO:0045948 | positive regulation of translational initiation | 3 | POLR2G,RPS6KB1,IMPACT | 22 | 0.1145916 |
| GO:BP | GO:0070932 | histone H3 deacetylation | 1 | HDAC1 | 6 | 0.1145916 |
| GO:BP | GO:0060831 | smoothened signaling pathway involved in dorsal/ventral neural tube patterning | 1 | CPLANE2 | 14 | 0.1145916 |
| GO:BP | GO:0080135 | regulation of cellular response to stress | 14 | VPS72,AIDA,ANKRD1,KAT5,RAD9A,GSTP1,AQP11,CRY1,TRIAP1,KMT5A,PML,ERCC4,TERF2IP,PAFAH1B1 | 585 | 0.1145916 |
| GO:BP | GO:0061196 | fungiform papilla development | 1 | HDAC1 | 5 | 0.1145916 |
| GO:BP | GO:0060789 | hair follicle placode formation | 1 | HDAC1 | 5 | 0.1145916 |
| GO:BP | GO:1901796 | regulation of signal transduction by p53 class mediator | 5 | ANKRD1,TRIAP1,KMT5A,PML,HEXIM1 | 101 | 0.1178069 |
| GO:BP | GO:0046329 | negative regulation of JNK cascade | 3 | AIDA,GSTP1,PAFAH1B1 | 36 | 0.1196998 |
| GO:BP | GO:0007341 | penetration of zona pellucida | 1 | PITHD1 | 4 | 0.1203858 |
| GO:BP | GO:1901523 | icosanoid catabolic process | 1 | LYPLA2 | 2 | 0.1203858 |
| GO:BP | GO:0051493 | regulation of cytoskeleton organization | 14 | ARHGEF10L,ASAP3,CCSAP,SYNPO2L,ARFIP2,RBM14,ARAP1,NAV3,TTC8,CHMP1A,PAFAH1B1,CHMP6,RAC3,SYDE1 | 429 | 0.1216089 |
| GO:BP | GO:0031860 | telomeric 3’ overhang formation | 1 | DCLRE1B | 4 | 0.1219149 |
| GO:BP | GO:0006476 | protein deacetylation | 6 | HDAC1,BRMS1,PML,MIER2,MTA3,CTBP1 | 81 | 0.1220752 |
| GO:BP | GO:0097711 | ciliary basal body-plasma membrane docking | 1 | RAB3IP | 1 | 0.1263107 |
| GO:BP | GO:0051146 | striated muscle cell differentiation | 5 | LMNA,PPP3CB,SYNPO2L,ANKRD1,BDNF | 239 | 0.1272256 |
| GO:BP | GO:0032933 | SREBP signaling pathway | 1 | ARHGEF10L | 14 | 0.1272256 |
| GO:BP | GO:0000724 | double-strand break repair via homologous recombination | 9 | VPS72,KAT5,KMT5A,ERCC4,TERF2IP,PIAS4,PSMD14,AP5S1,ACTL6A | 155 | 0.1272256 |
| GO:BP | GO:1900453 | negative regulation of long-term synaptic depression | 1 | ADORA1 | 3 | 0.1272256 |
| GO:BP | GO:0045654 | positive regulation of megakaryocyte differentiation | 1 | PITHD1 | 9 | 0.1272256 |
| GO:BP | GO:0071985 | multivesicular body sorting pathway | 4 | VPS37C,CHMP1A,CHMP6,STAM2 | 47 | 0.1273346 |
| GO:BP | GO:0051469 | vesicle fusion with vacuole | 2 | CHMP1A,CHMP6 | 11 | 0.1321321 |
| GO:BP | GO:0061763 | multivesicular body-lysosome fusion | 2 | CHMP1A,CHMP6 | 11 | 0.1321321 |
| GO:BP | GO:0071501 | cellular response to sterol depletion | 1 | ARHGEF10L | 14 | 0.1321321 |
| GO:BP | GO:0048284 | organelle fusion | 2 | CPLANE2,STX12 | 133 | 0.1322348 |
| GO:BP | GO:0006890 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | 5 | SCYL1,COG7,PICK1,TMEM115,RINT1 | 51 | 0.1334183 |
| GO:BP | GO:0006470 | protein dephosphorylation | 4 | DUSP12,TIPRL,ADORA1,PPP3CB | 211 | 0.1350555 |
| GO:BP | GO:0031550 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway | 1 | BDNF | 2 | 0.1361341 |
| GO:BP | GO:0007031 | peroxisome organization | 1 | PEX14 | 34 | 0.1361341 |
| GO:BP | GO:0009116 | nucleoside metabolic process | 1 | ICMT | 41 | 0.1361341 |
| GO:BP | GO:0000725 | recombinational repair | 9 | VPS72,KAT5,KMT5A,ERCC4,TERF2IP,PIAS4,PSMD14,AP5S1,ACTL6A | 159 | 0.1361341 |
| GO:BP | GO:1900864 | mitochondrial RNA modification | 2 | TRMT61B,METTL8 | 9 | 0.1361341 |
| GO:BP | GO:1904385 | cellular response to angiotensin | 1 | AGTRAP | 24 | 0.1361341 |
| GO:BP | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway | 3 | VPS37C,CHMP6,STAM2 | 27 | 0.1361341 |
| GO:BP | GO:0044743 | protein transmembrane import into intracellular organelle | 1 | PEX14 | 36 | 0.1361341 |
| GO:BP | GO:0021522 | spinal cord motor neuron differentiation | 2 | LMO4,SCYL1 | 17 | 0.1361341 |
| GO:BP | GO:2000036 | regulation of stem cell population maintenance | 6 | HDAC1,BRMS1,ING1,SMARCB1,ACTL6A,ZNF706 | 63 | 0.1361341 |
| GO:BP | GO:0051102 | DNA ligation involved in DNA recombination | 1 | LIG4 | 1 | 0.1361341 |
| GO:BP | GO:0075713 | establishment of integrated proviral latency | 1 | LIG4 | 1 | 0.1361341 |
| GO:BP | GO:0010639 | negative regulation of organelle organization | 9 | LMNA,BUB3,RBM14,ARAP1,NAV3,TRIAP1,PML,ERCC4,TERF2IP | 311 | 0.1361341 |
| GO:BP | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity | 1 | LMNA | 4 | 0.1361341 |
| GO:BP | GO:0032968 | positive regulation of transcription elongation by RNA polymerase II | 5 | MED8,MED17,MED15,MED7,MED22 | 48 | 0.1361341 |
| GO:BP | GO:0070900 | mitochondrial tRNA modification | 2 | TRMT61B,METTL8 | 9 | 0.1361341 |
| GO:BP | GO:0006991 | response to sterol depletion | 1 | ARHGEF10L | 16 | 0.1361341 |
| GO:BP | GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 1 | WRAP73 | 92 | 0.1361341 |
| GO:BP | GO:0042159 | lipoprotein catabolic process | 2 | LYPLA2,ABHD13 | 15 | 0.1361341 |
| GO:BP | GO:0001909 | leukocyte mediated cytotoxicity | 2 | PLEKHM2,RNF19B | 58 | 0.1362403 |
| GO:BP | GO:0090169 | regulation of spindle assembly | 3 | CCSAP,CHMP1A,CHMP6 | 32 | 0.1362403 |
| GO:BP | GO:0006997 | nucleus organization | 6 | LMNA,KAT5,PML,CHMP1A,PAFAH1B1,CHMP6 | 126 | 0.1362403 |
| GO:BP | GO:0071824 | protein-DNA complex organization | 30 | HDAC1,MED8,VPS72,LMNA,SUV39H2,NPM3,KAT5,RBM14,EMSY,MED17,KMT5A,ING1,BRF1,BAHD1,MIER2,MTA3,METTL8,INO80D,PHF20,N6AMT1,MED15,SMARCB1,PICK1,ACTL6A,CTBP1,NAP1L5,SMARCAD1,BDP1,MED7,HMGN4 | 713 | 0.1362403 |
| GO:BP | GO:0032049 | cardiolipin biosynthetic process | 2 | PGS1,TAMM41 | 7 | 0.1373550 |
| GO:BP | GO:0009304 | tRNA transcription | 2 | BRF1,GTF3C3 | 9 | 0.1373550 |
| GO:BP | GO:0032938 | negative regulation of translation in response to oxidative stress | 1 | PML | 1 | 0.1375007 |
| GO:BP | GO:0043556 | regulation of translation in response to oxidative stress | 1 | PML | 1 | 0.1375007 |
| GO:BP | GO:0097576 | vacuole fusion | 2 | CHMP1A,CHMP6 | 12 | 0.1375007 |
| GO:BP | GO:0045214 | sarcomere organization | 2 | SYNPO2L,ANKRD1 | 42 | 0.1393988 |
| GO:BP | GO:0022402 | cell cycle process | 26 | WRAP73,LMNA,TIPRL,SDE2,CCSAP,ECD,BUB3,STK33,KAT5,RBM14,RAD9A,CDK4,CRY1,TRIAP1,KMT5A,RAN,PML,ERCC4,E2F4,CHMP1A,PAFAH1B1,RPS6KB1,RPTOR,CHMP6,RIOK3,FZR1 | 1080 | 0.1393988 |
| GO:BP | GO:0051276 | chromosome organization | 13 | WRAP73,DCLRE1B,LMNA,CCSAP,BUB3,KAT5,KMT5A,RAN,LIG4,PML,ERCC4,TERF2IP,CHMP1A | 534 | 0.1399235 |
| GO:BP | GO:1905767 | regulation of double-stranded telomeric DNA binding | 1 | ERCC4 | 1 | 0.1399235 |
| GO:BP | GO:1905768 | negative regulation of double-stranded telomeric DNA binding | 1 | ERCC4 | 1 | 0.1399235 |
| GO:BP | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | 2 | DIABLO,BAK1 | 7 | 0.1399235 |
| GO:BP | GO:1990776 | response to angiotensin | 1 | AGTRAP | 25 | 0.1400550 |
| GO:BP | GO:0032898 | neurotrophin production | 1 | ADORA1 | 4 | 0.1400550 |
| GO:BP | GO:0042321 | negative regulation of circadian sleep/wake cycle, sleep | 1 | ADORA1 | 2 | 0.1400550 |
| GO:BP | GO:0051225 | spindle assembly | 1 | WRAP73 | 120 | 0.1400550 |
| GO:BP | GO:0110053 | regulation of actin filament organization | 2 | ARHGEF10L,ASAP3 | 224 | 0.1405167 |
| GO:BP | GO:0090398 | cellular senescence | 5 | LMNA,KAT5,PML,FZR1,MAP2K7 | 83 | 0.1405167 |
| GO:BP | GO:0000045 | autophagosome assembly | 7 | STX12,ARFIP2,RAB1A,NSFL1C,TMEM39A,RAB7A,RAB23 | 100 | 0.1405167 |
| GO:BP | GO:0007052 | mitotic spindle organization | 1 | WRAP73 | 128 | 0.1405167 |
| GO:BP | GO:0090312 | positive regulation of protein deacetylation | 3 | BRMS1,PML,CTBP1 | 21 | 0.1420162 |
| GO:BP | GO:0051664 | nuclear pore localization | 1 | LMNA | 5 | 0.1443339 |
| GO:BP | GO:0060271 | cilium assembly | 2 | WRAP73,CPLANE2 | 296 | 0.1443339 |
| GO:BP | GO:0043587 | tongue morphogenesis | 1 | HDAC1 | 7 | 0.1443339 |
| GO:BP | GO:0033131 | regulation of glucokinase activity | 2 | DUSP12,RANBP2 | 7 | 0.1444713 |
| GO:BP | GO:0031338 | regulation of vesicle fusion | 1 | CPLANE2 | 17 | 0.1449396 |
| GO:BP | GO:0062033 | positive regulation of mitotic sister chromatid segregation | 2 | KAT5,MAD1L1 | 6 | 0.1449396 |
| GO:BP | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation | 1 | PPP1CA | 2 | 0.1449396 |
| GO:BP | GO:0061025 | membrane fusion | 2 | CPLANE2,STX12 | 132 | 0.1449396 |
| GO:BP | GO:0007033 | vacuole organization | 10 | STX12,PPP3CB,ARFIP2,CHMP1A,HSD17B1,CHMP6,RAB1A,NSFL1C,TMEM39A,RAB7A | 199 | 0.1449396 |
| GO:BP | GO:0006392 | transcription elongation by mitochondrial RNA polymerase | 1 | TEFM | 1 | 0.1450065 |
| GO:BP | GO:0044772 | mitotic cell cycle phase transition | 19 | SDE2,ECD,BUB3,CDK4,TRIAP1,PML,E2F4,RPS6KB1,RPTOR,FZR1,ZNF324,MTA3,SMARCB1,TPRA1,ACTL6A,RIOK2,MAD1L1,HUS1,RINT1 | 411 | 0.1456733 |
| GO:BP | GO:0031400 | negative regulation of protein modification process | 12 | TIPRL,AIDA,BUB3,GSTP1,CRY1,GSKIP,TERF2IP,NXN,INCA1,HEXIM1,CHMP6,IMPACT | 396 | 0.1467858 |
| GO:BP | GO:0045905 | positive regulation of translational termination | 1 | JMJD4 | 4 | 0.1468739 |
| GO:BP | GO:0070925 | organelle assembly | 31 | WRAP73,CPLANE2,STX12,CCSAP,SYNPO2L,ANKRD1,ARFIP2,VPS37C,RBM14,RAB3IP,TTC8,EFL1,CLUAP1,CCDC113,E2F4,CHMP1A,PAFAH1B1,NLE1,MKS1,CHMP6,AP1M1,RAB1A,STAM2,SEPTIN2,NSFL1C,IFT52,TMEM39A,RAB7A,BBS7,NEK1,MACIR | 830 | 0.1472182 |
| GO:BP | GO:0006384 | transcription initiation at RNA polymerase III promoter | 2 | BRF1,BDP1 | 8 | 0.1472182 |
| GO:BP | GO:0021904 | dorsal/ventral neural tube patterning | 1 | CPLANE2 | 21 | 0.1472182 |
| GO:BP | GO:0080170 | hydrogen peroxide transmembrane transport | 1 | AQP11 | 1 | 0.1488927 |
| GO:BP | GO:0000056 | ribosomal small subunit export from nucleus | 2 | RAN,RIOK2 | 8 | 0.1495629 |
| GO:BP | GO:0051129 | negative regulation of cellular component organization | 14 | LMO4,LMNA,AIDA,BUB3,RBM14,ANKRD13D,ARAP1,RAB3IP,NAV3,TRIAP1,PML,ERCC4,TERF2IP,PAFAH1B1 | 593 | 0.1495629 |
| GO:BP | GO:0006364 | rRNA processing | 12 | NSUN4,SDE2,NPM3,UTP6,EIF4A3,RIOK3,TRMT61B,RIOK2,SRFBP1,NSUN5,NOL8,REXO4 | 215 | 0.1505370 |
| GO:BP | GO:0065002 | intracellular protein transmembrane transport | 1 | PEX14 | 53 | 0.1505370 |
| GO:BP | GO:1904572 | negative regulation of mRNA binding | 1 | EIF4A3 | 1 | 0.1505370 |
| GO:BP | GO:0045188 | regulation of circadian sleep/wake cycle, non-REM sleep | 1 | ADORA1 | 2 | 0.1505370 |
| GO:BP | GO:0007076 | mitotic chromosome condensation | 3 | KMT5A,CHMP1A,SMC2 | 19 | 0.1505370 |
| GO:BP | GO:0044843 | cell cycle G1/S phase transition | 11 | SDE2,ECD,CDK4,TRIAP1,PML,E2F4,RPS6KB1,RPTOR,ZNF324,SMARCB1,ACTL6A | 226 | 0.1505370 |
| GO:BP | GO:1904573 | regulation of selenocysteine insertion sequence binding | 1 | EIF4A3 | 1 | 0.1505370 |
| GO:BP | GO:0044782 | cilium organization | 2 | WRAP73,CPLANE2 | 317 | 0.1505370 |
| GO:BP | GO:0000723 | telomere maintenance | 9 | DCLRE1B,LMNA,PML,ERCC4,TERF2IP,MAP2K7,INO80D,ACTL6A,HUS1 | 142 | 0.1505370 |
| GO:BP | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 2 | CASC3,EIF4A3 | 12 | 0.1505370 |
| GO:BP | GO:0006281 | DNA repair | 25 | DCLRE1B,VPS72,DCLRE1A,KAT5,RAD9A,EMSY,KMT5A,LIG4,PML,ERCC4,TERF2IP,FZR1,PIAS4,PSMD14,INO80D,AP5S1,SMARCB1,ASCC2,ACTL6A,SMARCAD1,UFL1,HUS1,UBE2V2,APTX,REXO4 | 543 | 0.1505370 |
| GO:BP | GO:1901657 | glycosyl compound metabolic process | 1 | ICMT | 63 | 0.1505370 |
| GO:BP | GO:0048146 | positive regulation of fibroblast proliferation | 3 | CDK4,LIG4,PML | 43 | 0.1505370 |
| GO:BP | GO:0032206 | positive regulation of telomere maintenance | 5 | PML,TERF2IP,MAP2K7,INO80D,ACTL6A | 65 | 0.1505370 |
| GO:BP | GO:0072715 | cellular response to selenite ion | 1 | EIF4A3 | 1 | 0.1505370 |
| GO:BP | GO:0010616 | negative regulation of cardiac muscle adaptation | 1 | LMNA | 6 | 0.1505370 |
| GO:BP | GO:0097212 | lysosomal membrane organization | 2 | CHMP1A,CHMP6 | 12 | 0.1505370 |
| GO:BP | GO:1904902 | ESCRT III complex assembly | 1 | CHMP6 | 1 | 0.1505370 |
| GO:BP | GO:1904895 | ESCRT complex assembly | 1 | CHMP6 | 1 | 0.1505370 |
| GO:BP | GO:1904574 | negative regulation of selenocysteine insertion sequence binding | 1 | EIF4A3 | 1 | 0.1505370 |
| GO:BP | GO:1904569 | regulation of selenocysteine incorporation | 1 | EIF4A3 | 1 | 0.1505370 |
| GO:BP | GO:0003271 | smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation | 1 | MKS1 | 1 | 0.1505370 |
| GO:BP | GO:0045910 | negative regulation of DNA recombination | 3 | KAT5,KMT5A,TERF2IP | 35 | 0.1505370 |
| GO:BP | GO:1903243 | negative regulation of cardiac muscle hypertrophy in response to stress | 1 | LMNA | 6 | 0.1505370 |
| GO:BP | GO:0072714 | response to selenite ion | 1 | EIF4A3 | 1 | 0.1505370 |
| GO:BP | GO:1903299 | regulation of hexokinase activity | 2 | DUSP12,RANBP2 | 8 | 0.1505370 |
| GO:BP | GO:1904570 | negative regulation of selenocysteine incorporation | 1 | EIF4A3 | 1 | 0.1505370 |
| GO:BP | GO:0048672 | positive regulation of collateral sprouting | 2 | BDNF,BCL11A | 10 | 0.1505370 |
| GO:BP | GO:0016570 | histone modification | 12 | HDAC1,VPS72,SUV39H2,KAT5,BRMS1,PML,MIER2,MTA3,PHF20,ACTL6A,CTBP1,NELFA | 270 | 0.1505370 |
| GO:BP | GO:1990497 | regulation of cytoplasmic translation in response to stress | 1 | IMPACT | 1 | 0.1515128 |
| GO:BP | GO:0032970 | regulation of actin filament-based process | 6 | ARHGEF10L,ASAP3,ADORA1,SYNPO2L,ARFIP2,ARAP1 | 312 | 0.1515128 |
| GO:BP | GO:0050000 | chromosome localization | 5 | LMNA,BUB3,KAT5,CHMP1A,CHMP6 | 101 | 0.1515128 |
| GO:BP | GO:1990611 | regulation of cytoplasmic translational initiation in response to stress | 1 | IMPACT | 1 | 0.1515128 |
| GO:BP | GO:0051496 | positive regulation of stress fiber assembly | 2 | ARHGEF10L,SYNPO2L | 46 | 0.1529978 |
| GO:BP | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway | 1 | BDNF | 2 | 0.1531741 |
| GO:BP | GO:0072331 | signal transduction by p53 class mediator | 6 | ANKRD1,KAT5,TRIAP1,KMT5A,PML,HEXIM1 | 162 | 0.1534447 |
| GO:BP | GO:2000042 | negative regulation of double-strand break repair via homologous recombination | 2 | KAT5,KMT5A | 20 | 0.1534541 |
| GO:BP | GO:0032873 | negative regulation of stress-activated MAPK cascade | 3 | AIDA,GSTP1,PAFAH1B1 | 46 | 0.1534541 |
| GO:BP | GO:1901569 | fatty acid derivative catabolic process | 1 | LYPLA2 | 10 | 0.1534541 |
| GO:BP | GO:0060788 | ectodermal placode formation | 1 | HDAC1 | 10 | 0.1534541 |
| GO:BP | GO:1905673 | positive regulation of lysosome organization | 1 | PPP3CB | 3 | 0.1534541 |
| GO:BP | GO:0071697 | ectodermal placode morphogenesis | 1 | HDAC1 | 10 | 0.1534541 |
| GO:BP | GO:0061029 | eyelid development in camera-type eye | 1 | HDAC1 | 11 | 0.1534541 |
| GO:BP | GO:0098795 | global gene silencing by mRNA cleavage | 1 | CLP1 | 3 | 0.1534922 |
| GO:BP | GO:1904668 | positive regulation of ubiquitin protein ligase activity | 2 | PEX12,FZR1 | 12 | 0.1534922 |
| GO:BP | GO:1902229 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | 3 | RAD9A,TRIAP1,PIAS4 | 37 | 0.1534922 |
| GO:BP | GO:0006655 | phosphatidylglycerol biosynthetic process | 2 | PGS1,TAMM41 | 9 | 0.1539228 |
| GO:BP | GO:2001251 | negative regulation of chromosome organization | 4 | BUB3,PML,ERCC4,TERF2IP | 90 | 0.1539228 |
| GO:BP | GO:0030952 | establishment or maintenance of cytoskeleton polarity | 1 | LMNA | 7 | 0.1539228 |
| GO:BP | GO:0006378 | mRNA polyadenylation | 2 | CLP1,PCF11 | 26 | 0.1539228 |
| GO:BP | GO:0001708 | cell fate specification | 2 | HDAC1,LMO4 | 55 | 0.1539228 |
| GO:BP | GO:0043201 | response to leucine | 2 | RPS6KB1,RPTOR | 13 | 0.1539228 |
| GO:BP | GO:0032956 | regulation of actin cytoskeleton organization | 2 | ARHGEF10L,ASAP3 | 271 | 0.1539228 |
| GO:BP | GO:0051348 | negative regulation of transferase activity | 8 | AIDA,BUB3,GSTP1,GSKIP,PML,INCA1,HEXIM1,CHMP6 | 225 | 0.1539228 |
| GO:BP | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 2 | TRIAP1,PML | 18 | 0.1539228 |
| GO:BP | GO:0035019 | somatic stem cell population maintenance | 5 | VPS72,MED17,LIG4,MED15,MED7 | 50 | 0.1539228 |
| GO:BP | GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 1 | WRAP73 | 163 | 0.1539228 |
| GO:BP | GO:0032229 | negative regulation of synaptic transmission, GABAergic | 1 | ADORA1 | 3 | 0.1539228 |
| GO:BP | GO:0046761 | viral budding from plasma membrane | 2 | CHMP1A,CHMP6 | 13 | 0.1539228 |
| GO:BP | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress | 3 | DIABLO,GSKIP,PML | 51 | 0.1539228 |
| GO:BP | GO:0060491 | regulation of cell projection assembly | 1 | WRAP73 | 165 | 0.1539228 |
| GO:BP | GO:0072201 | negative regulation of mesenchymal cell proliferation | 1 | LMNA | 7 | 0.1539228 |
| GO:BP | GO:0044087 | regulation of cellular component biogenesis | 3 | WRAP73,ARHGEF10L,ASAP3 | 802 | 0.1539228 |
| GO:BP | GO:0032241 | positive regulation of nucleobase-containing compound transport | 1 | ADORA1 | 6 | 0.1539228 |
| GO:BP | GO:0014050 | negative regulation of glutamate secretion | 1 | ADORA1 | 3 | 0.1539228 |
| GO:BP | GO:0070303 | negative regulation of stress-activated protein kinase signaling cascade | 3 | AIDA,GSTP1,PAFAH1B1 | 47 | 0.1539228 |
| GO:BP | GO:0042748 | circadian sleep/wake cycle, non-REM sleep | 1 | ADORA1 | 3 | 0.1539228 |
| GO:BP | GO:0007507 | heart development | 6 | CPLANE2,LMO4,LMNA,PPP3CB,SYNPO2L,ANKRD1 | 512 | 0.1539228 |
| GO:BP | GO:0071696 | ectodermal placode development | 1 | HDAC1 | 11 | 0.1539228 |
| GO:BP | GO:0045210 | FasL biosynthetic process | 1 | PHLDA1 | 1 | 0.1539228 |
| GO:BP | GO:1905037 | autophagosome organization | 7 | STX12,ARFIP2,RAB1A,NSFL1C,TMEM39A,RAB7A,RAB23 | 107 | 0.1539228 |
| GO:BP | GO:0009785 | blue light signaling pathway | 1 | CRY1 | 2 | 0.1548506 |
| GO:BP | GO:0071483 | cellular response to blue light | 1 | CRY1 | 2 | 0.1548506 |
| GO:BP | GO:0007051 | spindle organization | 1 | WRAP73 | 189 | 0.1556824 |
| GO:BP | GO:0060173 | limb development | 2 | CPLANE2,HDAC1 | 141 | 0.1556824 |
| GO:BP | GO:0006289 | nucleotide-excision repair | 6 | KAT5,LIG4,ERCC4,SMARCB1,ACTL6A,HUS1 | 80 | 0.1556824 |
| GO:BP | GO:0071806 | protein transmembrane transport | 1 | PEX14 | 63 | 0.1556824 |
| GO:BP | GO:0048736 | appendage development | 2 | CPLANE2,HDAC1 | 141 | 0.1556824 |
| GO:BP | GO:1904195 | regulation of granulosa cell proliferation | 1 | MTA3 | 1 | 0.1564941 |
| GO:BP | GO:1904799 | regulation of neuron remodeling | 1 | BCL11A | 1 | 0.1564941 |
| GO:BP | GO:0060766 | negative regulation of androgen receptor signaling pathway | 1 | HDAC1 | 12 | 0.1564941 |
| GO:BP | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process | 1 | GSTP1 | 3 | 0.1564941 |
| GO:BP | GO:0008104 | protein localization | 4 | ICMT,PEX14,PLEKHM2,CPLANE2 | 2128 | 0.1564941 |
| GO:BP | GO:0031507 | heterochromatin formation | 2 | HDAC1,LMNA | 75 | 0.1564941 |
| GO:BP | GO:1904800 | negative regulation of neuron remodeling | 1 | BCL11A | 1 | 0.1564941 |
| GO:BP | GO:0006606 | protein import into nucleus | 5 | IPO13,LMNA,RAN,ING1,PML | 146 | 0.1564941 |
| GO:BP | GO:1902115 | regulation of organelle assembly | 1 | WRAP73 | 189 | 0.1564941 |
| GO:BP | GO:0061015 | snRNA import into nucleus | 1 | RAN | 2 | 0.1564941 |
| GO:BP | GO:0035281 | pre-miRNA export from nucleus | 1 | RAN | 2 | 0.1564941 |
| GO:BP | GO:0008617 | guanosine metabolic process | 1 | DGUOK | 1 | 0.1564941 |
| GO:BP | GO:0032703 | negative regulation of interleukin-2 production | 2 | KAT5,NAV3 | 10 | 0.1564941 |
| GO:BP | GO:0070727 | cellular macromolecule localization | 4 | ICMT,PEX14,PLEKHM2,CPLANE2 | 2137 | 0.1564941 |
| GO:BP | GO:1904197 | positive regulation of granulosa cell proliferation | 1 | MTA3 | 1 | 0.1564941 |
| GO:BP | GO:0043922 | negative regulation by host of viral transcription | 1 | HDAC1 | 11 | 0.1564941 |
| GO:BP | GO:1901068 | guanosine-containing compound metabolic process | 1 | DGUOK | 1 | 0.1564941 |
| GO:BP | GO:2000173 | negative regulation of branching morphogenesis of a nerve | 1 | BCL11A | 1 | 0.1564941 |
| GO:BP | GO:1990739 | granulosa cell proliferation | 1 | MTA3 | 1 | 0.1564941 |
| GO:BP | GO:0010498 | proteasomal protein catabolic process | 20 | PITHD1,RNF19B,TRIM3,KAT5,AQP11,UBAC2,TRIP4,PML,PEX12,OSBPL7,SPOP,FZR1,PSMD14,NSFL1C,ASCC2,BBS7,UFL1,FBXL4,PSMB1,RNF216 | 481 | 0.1564941 |
| GO:BP | GO:0033484 | intracellular nitric oxide homeostasis | 1 | GSTP1 | 3 | 0.1564941 |
| GO:BP | GO:0097191 | extrinsic apoptotic signaling pathway | 6 | LMNA,BLOC1S2,PPP1CA,GSTP1,DIABLO,PML | 182 | 0.1569972 |
| GO:BP | GO:0046753 | non-lytic viral release | 2 | CHMP1A,CHMP6 | 14 | 0.1577353 |
| GO:BP | GO:0051983 | regulation of chromosome segregation | 8 | BUB3,KAT5,SMARCB1,ACTL6A,RIOK2,MAD1L1,CDCA2,SMC2 | 121 | 0.1581493 |
| GO:BP | GO:0014745 | negative regulation of muscle adaptation | 1 | LMNA | 8 | 0.1591396 |
| GO:BP | GO:0097240 | chromosome attachment to the nuclear envelope | 1 | LMNA | 3 | 0.1591396 |
| GO:BP | GO:0006575 | cellular modified amino acid metabolic process | 1 | ICMT | 93 | 0.1603920 |
| GO:BP | GO:0044182 | filamentous growth of a population of unicellular organisms | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0090199 | regulation of release of cytochrome c from mitochondria | 4 | LMNA,TRIAP1,PARL,BAK1 | 37 | 0.1603920 |
| GO:BP | GO:1900428 | regulation of filamentous growth of a population of unicellular organisms | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0043687 | post-translational protein modification | 12 | ICMT,HDAC1,RNF19B,MED8,VPS72,SDE2,SUV39H2,HERC4,BUB3,TRIM3,KAT5,BRMS1 | 1100 | 0.1603920 |
| GO:BP | GO:0140056 | organelle localization by membrane tethering | 3 | STX12,PSEN2,RAB3IP | 69 | 0.1603920 |
| GO:BP | GO:0035304 | regulation of protein dephosphorylation | 2 | TIPRL,ADORA1 | 72 | 0.1603920 |
| GO:BP | GO:1900221 | regulation of amyloid-beta clearance | 1 | HDAC1 | 13 | 0.1603920 |
| GO:BP | GO:0006886 | intracellular protein transport | 2 | ICMT,PEX14 | 805 | 0.1603920 |
| GO:BP | GO:0016925 | protein sumoylation | 5 | PML,PIAS4,BCL11A,RANBP2,ZNF451 | 60 | 0.1603920 |
| GO:BP | GO:1903242 | regulation of cardiac muscle hypertrophy in response to stress | 1 | LMNA | 9 | 0.1603920 |
| GO:BP | GO:0051170 | import into nucleus | 5 | IPO13,LMNA,RAN,ING1,PML | 151 | 0.1603920 |
| GO:BP | GO:0021520 | spinal cord motor neuron cell fate specification | 1 | LMO4 | 5 | 0.1603920 |
| GO:BP | GO:0021532 | neural tube patterning | 1 | CPLANE2 | 31 | 0.1603920 |
| GO:BP | GO:1900430 | positive regulation of filamentous growth of a population of unicellular organisms | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:1900461 | positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0051246 | regulation of protein metabolic process | 42 | PITHD1,HDAC1,RNF19B,TIPRL,ADORA1,AIDA,JMJD4,BUB3,TRIM3,BDNF,POLR2G,KAT5,BRMS1,PPP1CA,GSTP1,AQP11,TBK1,CRY1,TRIAP1,DIABLO,GSKIP,PML,WDR24,ARL2BP,TERF2IP,NXN,INCA1,NLE1,PEX12,CASC3,HEXIM1,OSBPL7,SPOP,RPS6KB1,EIF4A3,RPTOR,CHMP6,IMPACT,MOB3A,FZR1,PIAS4,MAP2K7 | 1893 | 0.1603920 |
| GO:BP | GO:0090033 | positive regulation of filamentous growth | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:1902903 | regulation of supramolecular fiber organization | 2 | ARHGEF10L,ASAP3 | 321 | 0.1603920 |
| GO:BP | GO:0043414 | macromolecule methylation | 12 | ICMT,NSUN4,SUV39H2,KMT5A,TRMT61B,METTL8,PHF20,N6AMT1,NELFA,PRMT9,MTO1,NSUN5 | 238 | 0.1603920 |
| GO:BP | GO:0070786 | positive regulation of growth of unicellular organism as a thread of attached cells | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0003203 | endocardial cushion morphogenesis | 1 | CPLANE2 | 36 | 0.1603920 |
| GO:BP | GO:1990849 | vacuolar localization | 3 | PLEKHM2,BLOC1S2,C12orf4 | 61 | 0.1603920 |
| GO:BP | GO:1990456 | mitochondrion-endoplasmic reticulum membrane tethering | 1 | PSEN2 | 7 | 0.1603920 |
| GO:BP | GO:0061136 | regulation of proteasomal protein catabolic process | 2 | PITHD1,RNF19B | 179 | 0.1603920 |
| GO:BP | GO:0060236 | regulation of mitotic spindle organization | 3 | CCSAP,CHMP1A,CHMP6 | 42 | 0.1603920 |
| GO:BP | GO:0032233 | positive regulation of actin filament bundle assembly | 2 | ARHGEF10L,SYNPO2L | 53 | 0.1603920 |
| GO:BP | GO:0030447 | filamentous growth | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0010570 | regulation of filamentous growth | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0007124 | pseudohyphal growth | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:2000222 | positive regulation of pseudohyphal growth | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0010612 | regulation of cardiac muscle adaptation | 1 | LMNA | 9 | 0.1603920 |
| GO:BP | GO:2000220 | regulation of pseudohyphal growth | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport | 2 | SLC35B1,SLC35C2 | 12 | 0.1603920 |
| GO:BP | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway | 2 | CHMP1A,CHMP6 | 17 | 0.1603920 |
| GO:BP | GO:1901647 | positive regulation of synoviocyte proliferation | 1 | SAAL1 | 3 | 0.1603920 |
| GO:BP | GO:0070784 | regulation of growth of unicellular organism as a thread of attached cells | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0032418 | lysosome localization | 3 | PLEKHM2,BLOC1S2,C12orf4 | 61 | 0.1603920 |
| GO:BP | GO:0090646 | mitochondrial tRNA processing | 2 | TRMT61B,METTL8 | 13 | 0.1603920 |
| GO:BP | GO:1901645 | regulation of synoviocyte proliferation | 1 | SAAL1 | 3 | 0.1603920 |
| GO:BP | GO:0002941 | synoviocyte proliferation | 1 | SAAL1 | 3 | 0.1603920 |
| GO:BP | GO:0070783 | growth of unicellular organism as a thread of attached cells | 1 | SMARCB1 | 1 | 0.1603920 |
| GO:BP | GO:0048511 | rhythmic process | 7 | HDAC1,ADORA1,SUV39H2,KAT5,PPP1CA,CRY1,PML | 231 | 0.1603920 |
| GO:BP | GO:0009314 | response to radiation | 9 | SDE2,KAT5,RAD9A,PPP1CA,CRY1,TRIAP1,LIG4,PML,ERCC4 | 338 | 0.1603920 |
| GO:BP | GO:0046039 | GTP metabolic process | 3 | RAN,EFL1,RAB23 | 20 | 0.1603920 |
| GO:BP | GO:0018205 | peptidyl-lysine modification | 12 | VPS72,SUV39H2,KAT5,KMT5A,PML,PIAS4,BCL11A,RANBP2,PHF20,ACTL6A,CTBP1,NELFA | 286 | 0.1604407 |
| GO:BP | GO:0008608 | attachment of spindle microtubules to kinetochore | 2 | BUB3,KAT5 | 42 | 0.1604407 |
| GO:BP | GO:0044092 | negative regulation of molecular function | 20 | PEX14,TIPRL,AIDA,PPP3CB,BUB3,BRMS1,PPP1CA,GSTP1,TRIAP1,TTC8,GSKIP,PML,ERCC4,ZFP90,INCA1,NLE1,HEXIM1,EIF4A3,CHMP6,PIAS4 | 730 | 0.1604407 |
| GO:BP | GO:0015031 | protein transport | 29 | ICMT,PEX14,CPLANE2,STX12,IPO13,LMNA,ADORA1,COG2,PPP3CB,ANKRD1,AP2A2,TRIM3,ARFIP2,VPS37C,AQP11,NECAP1,MON2,RAB3IP,RAN,UBAC2,ING1,TTC8,PML,COG7,CHMP1A,PAFAH1B1,RABEP1,PEX12,SNX11 | 1368 | 0.1604407 |
| GO:BP | GO:0032786 | positive regulation of DNA-templated transcription, elongation | 5 | MED8,MED17,MED15,MED7,MED22 | 58 | 0.1604407 |
| GO:BP | GO:0000018 | regulation of DNA recombination | 7 | VPS72,KAT5,KMT5A,TERF2IP,PIAS4,ACTL6A,SMARCAD1 | 103 | 0.1604407 |
| GO:BP | GO:2000781 | positive regulation of double-strand break repair | 6 | VPS72,KAT5,PIAS4,SMARCB1,ACTL6A,UBE2V2 | 79 | 0.1608806 |
| GO:BP | GO:1901255 | nucleotide-excision repair involved in interstrand cross-link repair | 1 | ERCC4 | 2 | 0.1613488 |
| GO:BP | GO:1904743 | negative regulation of telomeric DNA binding | 1 | ERCC4 | 2 | 0.1613488 |
| GO:BP | GO:0051656 | establishment of organelle localization | 10 | PEX14,TRAPPC3,LMNA,BLOC1S2,BUB3,KAT5,C12orf4,RAN,CHMP1A,PAFAH1B1 | 397 | 0.1614187 |
| GO:BP | GO:0070828 | heterochromatin organization | 2 | HDAC1,LMNA | 83 | 0.1614187 |
| GO:BP | GO:0072384 | organelle transport along microtubule | 1 | PEX14 | 83 | 0.1629970 |
| GO:BP | GO:0021527 | spinal cord association neuron differentiation | 1 | LMO4 | 3 | 0.1629970 |
| GO:BP | GO:0070255 | regulation of mucus secretion | 1 | ADORA1 | 6 | 0.1629970 |
| GO:BP | GO:0042254 | ribosome biogenesis | 9 | NSUN4,SDE2,NPM3,RAN,EFL1,UTP6,NLE1,EIF4A3,RIOK3 | 315 | 0.1657902 |
| GO:BP | GO:0021517 | ventral spinal cord development | 2 | LMO4,SCYL1 | 25 | 0.1657902 |
| GO:BP | GO:0051457 | maintenance of protein location in nucleus | 2 | PML,ARL2BP | 22 | 0.1660015 |
| GO:BP | GO:0072695 | regulation of DNA recombination at telomere | 1 | TERF2IP | 2 | 0.1667980 |
| GO:BP | GO:0048239 | negative regulation of DNA recombination at telomere | 1 | TERF2IP | 2 | 0.1667980 |
| GO:BP | GO:0008213 | protein alkylation | 1 | ICMT | 125 | 0.1667980 |
| GO:BP | GO:0006479 | protein methylation | 1 | ICMT | 125 | 0.1667980 |
| GO:BP | GO:0090241 | negative regulation of histone H4 acetylation | 1 | CTBP1 | 1 | 0.1672396 |
| GO:BP | GO:0140014 | mitotic nuclear division | 8 | WRAP73,CCSAP,BUB3,KAT5,KMT5A,RAN,CHMP1A,CHMP6 | 251 | 0.1679100 |
| GO:BP | GO:0055015 | ventricular cardiac muscle cell development | 1 | LMNA | 10 | 0.1682189 |
| GO:BP | GO:0051012 | microtubule sliding | 1 | PAFAH1B1 | 2 | 0.1682189 |
| GO:BP | GO:0060119 | inner ear receptor cell development | 3 | TTC8,PAFAH1B1,MKS1 | 33 | 0.1682189 |
| GO:BP | GO:0043586 | tongue development | 1 | HDAC1 | 15 | 0.1682189 |
| GO:BP | GO:0044565 | dendritic cell proliferation | 1 | TBK1 | 3 | 0.1684101 |
| GO:BP | GO:0032091 | negative regulation of protein binding | 1 | PEX14 | 77 | 0.1684101 |
| GO:BP | GO:2000202 | positive regulation of ribosomal subunit export from nucleus | 1 | RIOK2 | 1 | 0.1689207 |
| GO:BP | GO:0021514 | ventral spinal cord interneuron differentiation | 1 | LMO4 | 5 | 0.1689207 |
| GO:BP | GO:0015780 | nucleotide-sugar transmembrane transport | 2 | SLC35B1,SLC35C2 | 13 | 0.1689207 |
| GO:BP | GO:1901685 | glutathione derivative metabolic process | 1 | GSTP1 | 3 | 0.1689207 |
| GO:BP | GO:1901687 | glutathione derivative biosynthetic process | 1 | GSTP1 | 3 | 0.1689207 |
| GO:BP | GO:2000208 | positive regulation of ribosomal small subunit export from nucleus | 1 | RIOK2 | 1 | 0.1689207 |
| GO:BP | GO:2001234 | negative regulation of apoptotic signaling pathway | 7 | HDAC1,LMNA,BDNF,GSTP1,TRIAP1,NLE1,RPS6KB1 | 200 | 0.1689207 |
| GO:BP | GO:2000206 | regulation of ribosomal small subunit export from nucleus | 1 | RIOK2 | 1 | 0.1689207 |
| GO:BP | GO:2000200 | regulation of ribosomal subunit export from nucleus | 1 | RIOK2 | 1 | 0.1689207 |
| GO:BP | GO:0035891 | exit from host cell | 3 | CHMP1A,CHMP6,RAB7A | 28 | 0.1689207 |
| GO:BP | GO:2000199 | positive regulation of ribonucleoprotein complex localization | 1 | RIOK2 | 1 | 0.1689207 |
| GO:BP | GO:2000626 | negative regulation of miRNA catabolic process | 1 | TENT2 | 1 | 0.1689207 |
| GO:BP | GO:1904886 | beta-catenin destruction complex disassembly | 1 | PPP1CA | 4 | 0.1689207 |
| GO:BP | GO:0060261 | positive regulation of transcription initiation by RNA polymerase II | 5 | MED8,MED17,MED15,MED7,MED22 | 60 | 0.1689207 |
| GO:BP | GO:0019076 | viral release from host cell | 3 | CHMP1A,CHMP6,RAB7A | 28 | 0.1689207 |
| GO:BP | GO:0070898 | RNA polymerase III preinitiation complex assembly | 1 | BDP1 | 1 | 0.1689207 |
| GO:BP | GO:0036120 | cellular response to platelet-derived growth factor stimulus | 1 | HDAC1 | 20 | 0.1689296 |
| GO:BP | GO:0015858 | nucleoside transport | 1 | ADORA1 | 8 | 0.1696194 |
| GO:BP | GO:0003093 | regulation of glomerular filtration | 1 | ADORA1 | 8 | 0.1696194 |
| GO:BP | GO:0051967 | negative regulation of synaptic transmission, glutamatergic | 1 | ADORA1 | 6 | 0.1696194 |
| GO:BP | GO:0022406 | membrane docking | 2 | STX12,PSEN2 | 79 | 0.1712066 |
| GO:BP | GO:0090224 | regulation of spindle organization | 3 | CCSAP,CHMP1A,CHMP6 | 45 | 0.1712066 |
| GO:BP | GO:0071482 | cellular response to light stimulus | 4 | SDE2,CRY1,TRIAP1,ERCC4 | 97 | 0.1713412 |
| GO:BP | GO:0045945 | positive regulation of transcription by RNA polymerase III | 2 | BRF1,RPTOR | 19 | 0.1721869 |
| GO:BP | GO:0031167 | rRNA methylation | 3 | NSUN4,TRMT61B,NSUN5 | 24 | 0.1727909 |
| GO:BP | GO:0006351 | DNA-templated transcription | 67 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,NPM3,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,PCF11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,ING1,SNAPC1,BRF1,BAHD1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,TEFM,HEXIM1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,MTA3,BCL11A | 2671 | 0.1729570 |
| GO:BP | GO:0061952 | midbody abscission | 2 | CHMP1A,CHMP6 | 17 | 0.1730341 |
| GO:BP | GO:0043124 | negative regulation of canonical NF-kappaB signal transduction | 3 | HDAC1,GSTP1,RIOK3 | 37 | 0.1737613 |
| GO:BP | GO:0003197 | endocardial cushion development | 1 | CPLANE2 | 46 | 0.1737613 |
| GO:BP | GO:0006338 | chromatin remodeling | 21 | HDAC1,VPS72,LMNA,SUV39H2,NPM3,KAT5,RBM14,KMT5A,BAHD1,MIER2,MTA3,METTL8,INO80D,PHF20,N6AMT1,SMARCB1,PICK1,ACTL6A,CTBP1,NAP1L5,SMARCAD1 | 522 | 0.1737613 |
| GO:BP | GO:0001906 | cell killing | 2 | PLEKHM2,RNF19B | 77 | 0.1737613 |
| GO:BP | GO:0032790 | ribosome disassembly | 2 | TRIP4,ASCC2 | 13 | 0.1737613 |
| GO:BP | GO:0009953 | dorsal/ventral pattern formation | 2 | CPLANE2,AIDA | 56 | 0.1737613 |
| GO:BP | GO:0006984 | ER-nucleus signaling pathway | 1 | ARHGEF10L | 44 | 0.1745258 |
| GO:BP | GO:0030239 | myofibril assembly | 2 | SYNPO2L,ANKRD1 | 66 | 0.1745258 |
| GO:BP | GO:0021515 | cell differentiation in spinal cord | 2 | LMO4,SCYL1 | 23 | 0.1745773 |
| GO:BP | GO:0098813 | nuclear chromosome segregation | 1 | WRAP73 | 264 | 0.1745773 |
| GO:BP | GO:0140694 | non-membrane-bounded organelle assembly | 10 | WRAP73,CCSAP,SYNPO2L,ANKRD1,RBM14,EFL1,E2F4,CHMP1A,NLE1,CHMP6 | 366 | 0.1752147 |
| GO:BP | GO:0045661 | regulation of myoblast differentiation | 5 | KAT5,TRIP4,SMARCB1,ACTL6A,PPARD | 60 | 0.1752147 |
| GO:BP | GO:0110012 | protein localization to P-body | 1 | TRAF3IP2 | 1 | 0.1752147 |
| GO:BP | GO:0120031 | plasma membrane bounded cell projection assembly | 2 | WRAP73,CPLANE2 | 463 | 0.1752147 |
| GO:BP | GO:0002334 | transitional two stage B cell differentiation | 1 | TRAF3IP2 | 1 | 0.1752147 |
| GO:BP | GO:0036119 | response to platelet-derived growth factor | 1 | HDAC1 | 22 | 0.1753686 |
| GO:BP | GO:0071705 | nitrogen compound transport | 38 | ICMT,PEX14,CPLANE2,STX12,IPO13,LMNA,ADORA1,COG2,PPP3CB,ANKRD1,AP2A2,TRIM3,ARFIP2,VPS37C,AQP11,NECAP1,SLC48A1,MON2,RAB3IP,GLTP,RAN,UBAC2,ING1,TTC8,PML,COG7,SLC12A4,CHMP1A,PAFAH1B1,RABEP1,PEX12,CASC3,SNX11,SLC35B1,SRSF1,SRP68,EIF4A3,CHMP6 | 1692 | 0.1758015 |
| GO:BP | GO:0007220 | Notch receptor processing | 1 | PSEN2 | 9 | 0.1758015 |
| GO:BP | GO:0042692 | muscle cell differentiation | 5 | LMNA,PPP3CB,SYNPO2L,ANKRD1,BDNF | 329 | 0.1780040 |
| GO:BP | GO:0014886 | transition between slow and fast fiber | 1 | GTF2IRD1 | 1 | 0.1780490 |
| GO:BP | GO:0000132 | establishment of mitotic spindle orientation | 3 | KAT5,PAFAH1B1,NSFL1C | 32 | 0.1780490 |
| GO:BP | GO:1904613 | cellular response to 2,3,7,8-tetrachlorodibenzodioxine | 1 | SLC46A3 | 3 | 0.1780490 |
| GO:BP | GO:0030031 | cell projection assembly | 2 | WRAP73,CPLANE2 | 473 | 0.1781983 |
| GO:BP | GO:0045652 | regulation of megakaryocyte differentiation | 1 | PITHD1 | 23 | 0.1785292 |
| GO:BP | GO:0048262 | determination of dorsal/ventral asymmetry | 1 | AIDA | 6 | 0.1799928 |
| GO:BP | GO:0048193 | Golgi vesicle transport | 14 | TRAPPC3,COG2,SCYL1,MON2,RAB3IP,COG7,RABEP1,RAB1A,ARFGEF2,PICK1,TMEM115,RINT1,RAB14,SNX12 | 279 | 0.1799928 |
| GO:BP | GO:0010638 | positive regulation of organelle organization | 2 | WRAP73,ARHGEF10L | 434 | 0.1799928 |
| GO:BP | GO:0002673 | regulation of acute inflammatory response | 2 | ADORA1,GSTP1 | 22 | 0.1799928 |
| GO:BP | GO:0055002 | striated muscle cell development | 2 | SYNPO2L,ANKRD1 | 69 | 0.1799928 |
| GO:BP | GO:0008361 | regulation of cell size | 7 | BDNF,AQP11,E2F4,SLC12A4,PAFAH1B1,RPTOR,BCL11A | 160 | 0.1799928 |
| GO:BP | GO:1990786 | cellular response to dsDNA | 1 | RIOK3 | 2 | 0.1799928 |
| GO:BP | GO:0030490 | maturation of SSU-rRNA | 4 | UTP6,RIOK3,RIOK2,SRFBP1 | 53 | 0.1799928 |
| GO:BP | GO:0019043 | establishment of viral latency | 1 | LIG4 | 3 | 0.1799928 |
| GO:BP | GO:1903050 | regulation of proteolysis involved in protein catabolic process | 2 | PITHD1,RNF19B | 210 | 0.1799928 |
| GO:BP | GO:0042275 | error-free postreplication DNA repair | 1 | UBE2V2 | 1 | 0.1799928 |
| GO:BP | GO:0044089 | positive regulation of cellular component biogenesis | 2 | WRAP73,ARHGEF10L | 420 | 0.1799928 |
| GO:BP | GO:1905215 | negative regulation of RNA binding | 1 | EIF4A3 | 2 | 0.1799928 |
| GO:BP | GO:0009411 | response to UV | 8 | SDE2,TRIAP1,PML,ERCC4,MAP2K7,MAP4K3,BAK1,HUS1 | 140 | 0.1799928 |
| GO:BP | GO:1990784 | response to dsDNA | 1 | RIOK3 | 2 | 0.1799928 |
| GO:BP | GO:0071264 | positive regulation of translational initiation in response to starvation | 1 | IMPACT | 2 | 0.1802887 |
| GO:BP | GO:0071262 | regulation of translational initiation in response to starvation | 1 | IMPACT | 2 | 0.1802887 |
| GO:BP | GO:0072132 | mesenchyme morphogenesis | 1 | CPLANE2 | 50 | 0.1802887 |
| GO:BP | GO:0006282 | regulation of DNA repair | 9 | VPS72,KAT5,KMT5A,PML,TERF2IP,PIAS4,INO80D,SMARCB1,ACTL6A | 202 | 0.1811612 |
| GO:BP | GO:0031346 | positive regulation of cell projection organization | 1 | WRAP73 | 301 | 0.1823089 |
| GO:BP | GO:0006465 | signal peptide processing | 2 | SPCS1,PARL | 13 | 0.1823089 |
| GO:BP | GO:0016485 | protein processing | 3 | CPLANE2,SDE2,PSEN2 | 185 | 0.1823089 |
| GO:BP | GO:0060887 | limb epidermis development | 1 | PIAS4 | 1 | 0.1823089 |
| GO:BP | GO:0007097 | nuclear migration | 2 | LMNA,PAFAH1B1 | 23 | 0.1823089 |
| GO:BP | GO:0097352 | autophagosome maturation | 4 | LIX1L,CHMP1A,CHMP6,TMEM39A | 54 | 0.1823089 |
| GO:BP | GO:0032691 | negative regulation of interleukin-1 beta production | 2 | GSTP1,PML | 13 | 0.1823089 |
| GO:BP | GO:0046464 | acylglycerol catabolic process | 1 | LYPLA2 | 22 | 0.1823089 |
| GO:BP | GO:0046461 | neutral lipid catabolic process | 1 | LYPLA2 | 22 | 0.1823089 |
| GO:BP | GO:0007015 | actin filament organization | 2 | ARHGEF10L,ASAP3 | 372 | 0.1823089 |
| GO:BP | GO:0043328 | protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | 2 | VPS37C,STAM2 | 16 | 0.1823089 |
| GO:BP | GO:0048560 | establishment of anatomical structure orientation | 1 | TTC8 | 2 | 0.1823089 |
| GO:BP | GO:0033047 | regulation of mitotic sister chromatid segregation | 2 | BUB3,KAT5 | 51 | 0.1831578 |
| GO:BP | GO:0048714 | positive regulation of oligodendrocyte differentiation | 1 | HDAC1 | 13 | 0.1831578 |
| GO:BP | GO:1904637 | cellular response to ionomycin | 1 | CDK4 | 3 | 0.1846708 |
| GO:BP | GO:0060058 | positive regulation of apoptotic process involved in mammary gland involution | 1 | PML | 3 | 0.1846708 |
| GO:BP | GO:0060057 | apoptotic process involved in mammary gland involution | 1 | PML | 3 | 0.1846708 |
| GO:BP | GO:0033762 | response to glucagon | 2 | CRY1,RPS6KB1 | 14 | 0.1846708 |
| GO:BP | GO:0045727 | positive regulation of translation | 6 | JMJD4,POLR2G,RPS6KB1,EIF4A3,IMPACT,METTL8 | 127 | 0.1846708 |
| GO:BP | GO:0051310 | metaphase chromosome alignment | 4 | BUB3,KAT5,CHMP1A,CHMP6 | 87 | 0.1846708 |
| GO:BP | GO:0010823 | negative regulation of mitochondrion organization | 4 | LMNA,TRIAP1,PARL,BAK1 | 45 | 0.1846708 |
| GO:BP | GO:1904636 | response to ionomycin | 1 | CDK4 | 3 | 0.1846708 |
| GO:BP | GO:0006449 | regulation of translational termination | 1 | JMJD4 | 10 | 0.1846708 |
| GO:BP | GO:0032774 | RNA biosynthetic process | 67 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,NPM3,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,PCF11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,ING1,SNAPC1,BRF1,BAHD1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,TEFM,HEXIM1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,MTA3,BCL11A | 2701 | 0.1880232 |
| GO:BP | GO:0033036 | macromolecule localization | 4 | ICMT,PEX14,PLEKHM2,CPLANE2 | 2446 | 0.1884188 |
| GO:BP | GO:0033144 | negative regulation of intracellular steroid hormone receptor signaling pathway | 2 | HDAC1,CRY1 | 30 | 0.1884188 |
| GO:BP | GO:1901991 | negative regulation of mitotic cell cycle phase transition | 9 | SDE2,BUB3,TRIAP1,PML,FZR1,TPRA1,MAD1L1,HUS1,RINT1 | 165 | 0.1884283 |
| GO:BP | GO:0021508 | floor plate formation | 1 | CLUAP1 | 3 | 0.1888782 |
| GO:BP | GO:0090435 | protein localization to nuclear envelope | 1 | LMNA | 14 | 0.1888964 |
| GO:BP | GO:0060765 | regulation of androgen receptor signaling pathway | 1 | HDAC1 | 24 | 0.1888964 |
| GO:BP | GO:0061819 | telomeric DNA-containing double minutes formation | 1 | ERCC4 | 3 | 0.1888964 |
| GO:BP | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 3 | SDE2,TRIAP1,PML | 64 | 0.1888964 |
| GO:BP | GO:0062196 | regulation of lysosome size | 1 | BLOC1S2 | 8 | 0.1888964 |
| GO:BP | GO:0016197 | endosomal transport | 12 | STX12,BLOC1S2,VPS37C,CHMP1A,CHMP6,EIPR1,STAM2,AP5S1,RAB7A,ZFYVE16,RAB14,SNX12 | 232 | 0.1888964 |
| GO:BP | GO:1905765 | negative regulation of protection from non-homologous end joining at telomere | 1 | ERCC4 | 3 | 0.1888964 |
| GO:BP | GO:0021915 | neural tube development | 2 | CPLANE2,LMO4 | 143 | 0.1888964 |
| GO:BP | GO:1905764 | regulation of protection from non-homologous end joining at telomere | 1 | ERCC4 | 3 | 0.1888964 |
| GO:BP | GO:1905665 | positive regulation of calcium ion import across plasma membrane | 2 | PPP3CB,PPP3CC | 6 | 0.1888964 |
| GO:BP | GO:0035588 | G protein-coupled purinergic receptor signaling pathway | 1 | ADORA1 | 7 | 0.1897216 |
| GO:BP | GO:0001973 | G protein-coupled adenosine receptor signaling pathway | 1 | ADORA1 | 7 | 0.1897216 |
| GO:BP | GO:1900272 | negative regulation of long-term synaptic potentiation | 1 | ADORA1 | 9 | 0.1897216 |
| GO:BP | GO:2000847 | negative regulation of corticosteroid hormone secretion | 1 | CRY1 | 4 | 0.1910116 |
| GO:BP | GO:2000832 | negative regulation of steroid hormone secretion | 1 | CRY1 | 4 | 0.1910116 |
| GO:BP | GO:2000850 | negative regulation of glucocorticoid secretion | 1 | CRY1 | 4 | 0.1910116 |
| GO:BP | GO:1905671 | regulation of lysosome organization | 1 | PPP3CB | 8 | 0.1910427 |
| GO:BP | GO:2000780 | negative regulation of double-strand break repair | 2 | KAT5,KMT5A | 32 | 0.1910427 |
| GO:BP | GO:0035621 | ER to Golgi ceramide transport | 1 | GLTP | 4 | 0.1910427 |
| GO:BP | GO:0008589 | regulation of smoothened signaling pathway | 2 | CPLANE2,HERC4 | 72 | 0.1910427 |
| GO:BP | GO:0071901 | negative regulation of protein serine/threonine kinase activity | 4 | AIDA,GSTP1,INCA1,HEXIM1 | 96 | 0.1910427 |
| GO:BP | GO:0001915 | negative regulation of T cell mediated cytotoxicity | 1 | PPP3CB | 3 | 0.1910427 |
| GO:BP | GO:0036211 | protein modification process | 25 | ICMT,LYPLA2,HDAC1,RNF19B,MED8,VPS72,DUSP12,TIPRL,PIGC,ADORA1,AIDA,SDE2,JMJD4,SUV39H2,HERC4,PPP3CB,BUB3,TRIM3,STK33,BDNF,SCYL1,KAT5,BRMS1,PPP1CA,GSTP1 | 2752 | 0.1914946 |
| GO:BP | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway | 1 | BDNF | 6 | 0.1923882 |
| GO:BP | GO:0071214 | cellular response to abiotic stimulus | 7 | SDE2,ANKRD1,RAD9A,CRY1,TRIAP1,LIG4,ERCC4 | 259 | 0.1923882 |
| GO:BP | GO:1905281 | positive regulation of retrograde transport, endosome to Golgi | 1 | EIPR1 | 2 | 0.1923882 |
| GO:BP | GO:0104004 | cellular response to environmental stimulus | 7 | SDE2,ANKRD1,RAD9A,CRY1,TRIAP1,LIG4,ERCC4 | 259 | 0.1923882 |
| GO:BP | GO:1904357 | negative regulation of telomere maintenance via telomere lengthening | 2 | PML,ERCC4 | 27 | 0.1923882 |
| GO:BP | GO:0034504 | protein localization to nucleus | 7 | IPO13,LMNA,PPP3CB,RAN,ING1,PML,ARL2BP | 282 | 0.1923882 |
| GO:BP | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 3 | CASC3,EIF4A3,SMG9 | 41 | 0.1923882 |
| GO:BP | GO:0031503 | protein-containing complex localization | 5 | LMNA,AP2A2,RAN,PML,CLUAP1 | 166 | 0.1923882 |
| GO:BP | GO:2000144 | positive regulation of DNA-templated transcription initiation | 5 | MED8,MED17,MED15,MED7,MED22 | 66 | 0.1924619 |
| GO:BP | GO:0031399 | regulation of protein modification process | 26 | TIPRL,ADORA1,AIDA,BUB3,BDNF,KAT5,BRMS1,GSTP1,TBK1,CRY1,GSKIP,PML,WDR24,ARL2BP,TERF2IP,NXN,INCA1,PEX12,HEXIM1,RPTOR,CHMP6,IMPACT,MOB3A,FZR1,PIAS4,MAP2K7 | 1094 | 0.1927663 |
| GO:BP | GO:0007059 | chromosome segregation | 1 | WRAP73 | 361 | 0.1932897 |
| GO:BP | GO:0034470 | ncRNA processing | 18 | NSUN4,SDE2,NPM3,CLP1,UTP6,INTS2,EIF4A3,RIOK3,TRMT61B,METTL8,RIOK2,SRFBP1,SRSF3,MTO1,NSUN5,INTS8,NOL8,REXO4 | 398 | 0.1933030 |
| GO:BP | GO:0055012 | ventricular cardiac muscle cell differentiation | 1 | LMNA | 15 | 0.1933030 |
| GO:BP | GO:0090176 | microtubule cytoskeleton organization involved in establishment of planar polarity | 1 | PAFAH1B1 | 3 | 0.1936594 |
| GO:BP | GO:0048521 | negative regulation of behavior | 1 | ADORA1 | 6 | 0.1941564 |
| GO:BP | GO:0061912 | selective autophagy | 3 | ARFIP2,TBK1,CRY1 | 92 | 0.1941564 |
| GO:BP | GO:0003084 | positive regulation of systemic arterial blood pressure | 1 | ADORA1 | 7 | 0.1941564 |
| GO:BP | GO:0032460 | negative regulation of protein oligomerization | 1 | BCL11A | 2 | 0.1941564 |
| GO:BP | GO:0032463 | negative regulation of protein homooligomerization | 1 | BCL11A | 2 | 0.1941564 |
| GO:BP | GO:0002087 | regulation of respiratory gaseous exchange by nervous system process | 1 | ADORA1 | 8 | 0.1941564 |
| GO:BP | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity | 1 | ADORA1 | 8 | 0.1941564 |
| GO:BP | GO:1901605 | alpha-amino acid metabolic process | 1 | ICMT | 151 | 0.1941564 |
| GO:BP | GO:0005981 | regulation of glycogen catabolic process | 1 | PPP1CA | 5 | 0.1941564 |
| GO:BP | GO:0016239 | positive regulation of macroautophagy | 3 | PAFAH1B2,TBK1,WDR24 | 70 | 0.1943483 |
| GO:BP | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production | 1 | GSTP1 | 3 | 0.1943483 |
| GO:BP | GO:1904888 | cranial skeletal system development | 1 | CPLANE2 | 51 | 0.1943483 |
| GO:BP | GO:0036444 | calcium import into the mitochondrion | 1 | PSEN2 | 12 | 0.1943483 |
| GO:BP | GO:0006404 | RNA import into nucleus | 1 | RAN | 4 | 0.1943483 |
| GO:BP | GO:0048208 | COPII vesicle coating | 1 | TRAPPC3 | 24 | 0.1959728 |
| GO:BP | GO:0000280 | nuclear division | 1 | WRAP73 | 343 | 0.1959728 |
| GO:BP | GO:0021516 | dorsal spinal cord development | 1 | LMO4 | 7 | 0.1959728 |
| GO:BP | GO:0034614 | cellular response to reactive oxygen species | 1 | PEX14 | 125 | 0.1959728 |
| GO:BP | GO:0034486 | vacuolar transmembrane transport | 1 | SLC46A3 | 3 | 0.1959728 |
| GO:BP | GO:0034141 | positive regulation of toll-like receptor 3 signaling pathway | 1 | TRIM3 | 7 | 0.1959728 |
| GO:BP | GO:1902774 | late endosome to lysosome transport | 2 | CHMP1A,CHMP6 | 20 | 0.1959728 |
| GO:BP | GO:0048207 | vesicle targeting, rough ER to cis-Golgi | 1 | TRAPPC3 | 24 | 0.1959728 |
| GO:BP | GO:2001235 | positive regulation of apoptotic signaling pathway | 5 | RAD9A,PPP1CA,PML,INCA1,PIAS4 | 113 | 0.1959728 |
| GO:BP | GO:1904155 | DN2 thymocyte differentiation | 1 | LIG4 | 1 | 0.1974401 |
| GO:BP | GO:0033153 | T cell receptor V(D)J recombination | 1 | LIG4 | 3 | 0.1974401 |
| GO:BP | GO:0106217 | tRNA C3-cytosine methylation | 1 | METTL8 | 2 | 0.1974401 |
| GO:BP | GO:0032200 | telomere organization | 8 | DCLRE1B,LMNA,PML,ERCC4,TERF2IP,MAP2K7,INO80D,ACTL6A | 156 | 0.1974401 |
| GO:BP | GO:0019042 | viral latency | 1 | LIG4 | 4 | 0.1974401 |
| GO:BP | GO:0002681 | somatic recombination of T cell receptor gene segments | 1 | LIG4 | 3 | 0.1974401 |
| GO:BP | GO:0002568 | somatic diversification of T cell receptor genes | 1 | LIG4 | 3 | 0.1974401 |
| GO:BP | GO:0045738 | negative regulation of DNA repair | 2 | KAT5,KMT5A | 34 | 0.1974401 |
| GO:BP | GO:0006346 | DNA methylation-dependent heterochromatin formation | 1 | HDAC1 | 22 | 0.1974401 |
| GO:BP | GO:0007224 | smoothened signaling pathway | 7 | CPLANE2,HERC4,CLUAP1,MKS1,SEPTIN2,IFT52,BBS7 | 123 | 0.1979427 |
| GO:BP | GO:0047496 | vesicle transport along microtubule | 3 | BLOC1S2,PAFAH1B1,RAB1A | 42 | 0.1979427 |
| GO:BP | GO:0070254 | mucus secretion | 1 | ADORA1 | 8 | 0.1979427 |
| GO:BP | GO:0001977 | renal system process involved in regulation of blood volume | 1 | ADORA1 | 8 | 0.1979427 |
| GO:BP | GO:0033045 | regulation of sister chromatid segregation | 6 | BUB3,KAT5,SMARCB1,ACTL6A,RIOK2,MAD1L1 | 99 | 0.1979427 |
| GO:BP | GO:1905691 | lipid droplet disassembly | 1 | KAT5 | 7 | 0.1979427 |
| GO:BP | GO:0080009 | mRNA methylation | 2 | TRMT61B,METTL8 | 18 | 0.1979427 |
| GO:BP | GO:0051123 | RNA polymerase II preinitiation complex assembly | 5 | MED8,MED17,MED15,MED7,MED22 | 54 | 0.1979427 |
| GO:BP | GO:0072334 | UDP-galactose transmembrane transport | 1 | SLC35B1 | 3 | 0.1979427 |
| GO:BP | GO:0051248 | negative regulation of protein metabolic process | 19 | TIPRL,AIDA,BUB3,TRIM3,POLR2G,GSTP1,AQP11,CRY1,TRIAP1,GSKIP,PML,TERF2IP,NXN,INCA1,NLE1,HEXIM1,EIF4A3,CHMP6,IMPACT | 799 | 0.1979427 |
| GO:BP | GO:0051984 | positive regulation of chromosome segregation | 3 | KAT5,MAD1L1,SMC2 | 27 | 0.1979427 |
| GO:BP | GO:1901985 | positive regulation of protein acetylation | 2 | KAT5,PML | 29 | 0.1979427 |
| GO:BP | GO:1904293 | negative regulation of ERAD pathway | 1 | AQP11 | 6 | 0.1979427 |
| GO:BP | GO:0000054 | ribosomal subunit export from nucleus | 2 | RAN,RIOK2 | 14 | 0.1984388 |
| GO:BP | GO:0033750 | ribosome localization | 2 | RAN,RIOK2 | 14 | 0.1984388 |
| GO:BP | GO:2000210 | positive regulation of anoikis | 1 | BRMS1 | 6 | 0.1985636 |
| GO:BP | GO:1904507 | positive regulation of telomere maintenance in response to DNA damage | 2 | INO80D,ACTL6A | 14 | 0.1985636 |
| GO:BP | GO:0006469 | negative regulation of protein kinase activity | 6 | AIDA,GSTP1,GSKIP,INCA1,HEXIM1,CHMP6 | 173 | 0.1985636 |
| GO:BP | GO:0043412 | macromolecule modification | 26 | ICMT,LYPLA2,HDAC1,RNF19B,MED8,NSUN4,VPS72,DUSP12,TIPRL,PIGC,ADORA1,AIDA,SDE2,JMJD4,SUV39H2,HERC4,PPP3CB,BUB3,TRIM3,STK33,BDNF,SCYL1,KAT5,BRMS1,PPP1CA,GSTP1 | 2949 | 0.1985636 |
| GO:BP | GO:1904780 | negative regulation of protein localization to centrosome | 1 | NSFL1C | 2 | 0.1985636 |
| GO:BP | GO:0007080 | mitotic metaphase chromosome alignment | 3 | KAT5,CHMP1A,CHMP6 | 55 | 0.1985636 |
| GO:BP | GO:1900122 | positive regulation of receptor binding | 1 | BDNF | 7 | 0.1987404 |
| GO:BP | GO:0001836 | release of cytochrome c from mitochondria | 4 | LMNA,TRIAP1,PARL,BAK1 | 46 | 0.1988759 |
| GO:BP | GO:0046600 | negative regulation of centriole replication | 1 | RBM14 | 7 | 0.1989293 |
| GO:BP | GO:0045931 | positive regulation of mitotic cell cycle | 5 | CDK4,PAFAH1B1,RPS6KB1,RPTOR,MTA3 | 111 | 0.1989293 |
| GO:BP | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | 2 | INCA1,HEXIM1 | 24 | 0.1989293 |
| GO:BP | GO:0051100 | negative regulation of binding | 1 | PEX14 | 133 | 0.1989293 |
| GO:BP | GO:0050893 | sensory processing | 1 | TTC8 | 4 | 0.1989620 |
| GO:BP | GO:1902807 | negative regulation of cell cycle G1/S phase transition | 3 | SDE2,TRIAP1,PML | 68 | 0.1991743 |
| GO:BP | GO:0010212 | response to ionizing radiation | 4 | KAT5,RAD9A,LIG4,PML | 127 | 0.1992926 |
| GO:BP | GO:0022616 | DNA strand elongation | 3 | DCLRE1B,INO80D,ACTL6A | 35 | 0.2001309 |
| GO:BP | GO:0051128 | regulation of cellular component organization | 4 | WRAP73,CPLANE2,ARHGEF10L,ASAP3 | 1981 | 0.2001309 |
| GO:BP | GO:0032048 | cardiolipin metabolic process | 2 | PGS1,TAMM41 | 13 | 0.2001309 |
| GO:BP | GO:1901875 | positive regulation of post-translational protein modification | 8 | CRY1,PML,PEX12,FZR1,PIAS4,PHF20,CTBP1,NELFA | 169 | 0.2001309 |
| GO:BP | GO:0008045 | motor neuron axon guidance | 2 | LMO4,RAC3 | 19 | 0.2001309 |
| GO:BP | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation | 1 | RPS6KB1 | 2 | 0.2009307 |
| GO:BP | GO:0031987 | locomotion involved in locomotory behavior | 1 | PPP3CB | 10 | 0.2011028 |
| GO:BP | GO:1900452 | regulation of long-term synaptic depression | 1 | ADORA1 | 11 | 0.2011028 |
| GO:BP | GO:0048285 | organelle fission | 1 | WRAP73 | 388 | 0.2011028 |
| GO:BP | GO:0099509 | regulation of presynaptic cytosolic calcium ion concentration | 1 | ADORA1 | 9 | 0.2011028 |
| GO:BP | GO:0040001 | establishment of mitotic spindle localization | 3 | KAT5,PAFAH1B1,NSFL1C | 37 | 0.2011028 |
| GO:BP | GO:0030162 | regulation of proteolysis | 3 | PITHD1,HDAC1,RNF19B | 522 | 0.2011028 |
| GO:BP | GO:0032239 | regulation of nucleobase-containing compound transport | 1 | ADORA1 | 15 | 0.2011028 |
| GO:BP | GO:0045187 | regulation of circadian sleep/wake cycle, sleep | 1 | ADORA1 | 8 | 0.2011028 |
| GO:BP | GO:0090235 | regulation of metaphase plate congression | 2 | KAT5,MAD1L1 | 13 | 0.2011028 |
| GO:BP | GO:0018872 | arsonoacetate metabolic process | 1 | N6AMT1 | 1 | 0.2014636 |
| GO:BP | GO:0032775 | DNA methylation on adenine | 1 | N6AMT1 | 2 | 0.2014636 |
| GO:BP | GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 5 | LMNA,PPP1CA,GSTP1,PML,RPS6KB1 | 124 | 0.2018220 |
| GO:BP | GO:0035303 | regulation of dephosphorylation | 2 | TIPRL,ADORA1 | 102 | 0.2018220 |
| GO:BP | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus | 3 | PPP3CB,PPARD,SRI | 19 | 0.2018220 |
| GO:BP | GO:0006399 | tRNA metabolic process | 9 | CLP1,BRF1,FARSA,TRMT61B,METTL8,GTF3C3,HARS2,RARS1,MTO1 | 190 | 0.2019888 |
| GO:BP | GO:0010803 | regulation of tumor necrosis factor-mediated signaling pathway | 3 | GSTP1,TBK1,PIAS4 | 45 | 0.2024837 |
| GO:BP | GO:0006310 | DNA recombination | 12 | VPS72,KAT5,KMT5A,LIG4,ERCC4,TERF2IP,PIAS4,PSMD14,INO80D,AP5S1,ACTL6A,SMARCAD1 | 262 | 0.2024837 |
| GO:BP | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission | 1 | EIF4A3 | 3 | 0.2024903 |
| GO:BP | GO:0099578 | regulation of translation at postsynapse, modulating synaptic transmission | 1 | EIF4A3 | 3 | 0.2024903 |
| GO:BP | GO:0043407 | negative regulation of MAP kinase activity | 2 | AIDA,GSTP1 | 50 | 0.2024903 |
| GO:BP | GO:1904030 | negative regulation of cyclin-dependent protein kinase activity | 2 | INCA1,HEXIM1 | 25 | 0.2027816 |
| GO:BP | GO:0032692 | negative regulation of interleukin-1 production | 2 | GSTP1,PML | 15 | 0.2030912 |
| GO:BP | GO:0045184 | establishment of protein localization | 13 | ICMT,PEX14,CPLANE2,STX12,IPO13,LMNA,ADORA1,COG2,PPP3CB,ANKRD1,AP2A2,TRIM3,ARFIP2 | 1470 | 0.2030912 |
| GO:BP | GO:0033505 | floor plate morphogenesis | 1 | CLUAP1 | 3 | 0.2030912 |
| GO:BP | GO:0010970 | transport along microtubule | 1 | PEX14 | 162 | 0.2030912 |
| GO:BP | GO:0071353 | cellular response to interleukin-4 | 2 | CDK4,PML | 23 | 0.2030912 |
| GO:BP | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process | 2 | TRMT61B,METTL8 | 16 | 0.2030912 |
| GO:BP | GO:0006913 | nucleocytoplasmic transport | 13 | IPO13,LMNA,RAN,ING1,PML,CASC3,EIF4A3,RANBP2,ANKRD54,RIOK2,SRSF3,RAB23,TRAF3IP2 | 294 | 0.2034188 |
| GO:BP | GO:1904742 | regulation of telomeric DNA binding | 1 | ERCC4 | 4 | 0.2034188 |
| GO:BP | GO:1904506 | negative regulation of telomere maintenance in response to DNA damage | 1 | ERCC4 | 3 | 0.2034188 |
| GO:BP | GO:0097242 | amyloid-beta clearance | 1 | HDAC1 | 27 | 0.2034188 |
| GO:BP | GO:0051169 | nuclear transport | 13 | IPO13,LMNA,RAN,ING1,PML,CASC3,EIF4A3,RANBP2,ANKRD54,RIOK2,SRSF3,RAB23,TRAF3IP2 | 294 | 0.2034188 |
| GO:BP | GO:0051294 | establishment of spindle orientation | 3 | KAT5,PAFAH1B1,NSFL1C | 37 | 0.2034902 |
| GO:BP | GO:0001933 | negative regulation of protein phosphorylation | 8 | AIDA,GSTP1,GSKIP,TERF2IP,INCA1,HEXIM1,CHMP6,IMPACT | 265 | 0.2034902 |
| GO:BP | GO:0051438 | regulation of ubiquitin-protein transferase activity | 3 | BUB3,PEX12,FZR1 | 51 | 0.2034902 |
| GO:BP | GO:0043433 | negative regulation of DNA-binding transcription factor activity | 1 | PEX14 | 136 | 0.2038302 |
| GO:BP | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway | 2 | GSTP1,PIAS4 | 17 | 0.2038302 |
| GO:BP | GO:0051956 | negative regulation of amino acid transport | 1 | ADORA1 | 11 | 0.2038302 |
| GO:BP | GO:0055089 | fatty acid homeostasis | 1 | ADORA1 | 12 | 0.2038302 |
| GO:BP | GO:1902425 | positive regulation of attachment of mitotic spindle microtubules to kinetochore | 1 | KAT5 | 8 | 0.2038302 |
| GO:BP | GO:1902423 | regulation of attachment of mitotic spindle microtubules to kinetochore | 1 | KAT5 | 8 | 0.2038302 |
| GO:BP | GO:0044065 | regulation of respiratory system process | 1 | ADORA1 | 11 | 0.2038302 |
| GO:BP | GO:0050802 | circadian sleep/wake cycle, sleep | 1 | ADORA1 | 9 | 0.2038302 |
| GO:BP | GO:0002449 | lymphocyte mediated immunity | 2 | PLEKHM2,RNF19B | 147 | 0.2038302 |
| GO:BP | GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 7 | SDE2,ECD,TRIAP1,PML,RPTOR,SMARCB1,ACTL6A | 146 | 0.2042930 |
| GO:BP | GO:0032957 | inositol trisphosphate metabolic process | 1 | IPMK | 10 | 0.2042930 |
| GO:BP | GO:1905786 | positive regulation of anaphase-promoting complex-dependent catabolic process | 1 | FZR1 | 2 | 0.2042930 |
| GO:BP | GO:0009992 | intracellular water homeostasis | 1 | AQP11 | 3 | 0.2042930 |
| GO:BP | GO:0015793 | glycerol transmembrane transport | 1 | AQP11 | 4 | 0.2042930 |
| GO:BP | GO:1905365 | regulation of intralumenal vesicle formation | 1 | RAB7A | 2 | 0.2048161 |
| GO:BP | GO:1904979 | negative regulation of endosome organization | 1 | RAB7A | 2 | 0.2048161 |
| GO:BP | GO:0007174 | epidermal growth factor catabolic process | 1 | RAB7A | 2 | 0.2048161 |
| GO:BP | GO:0035720 | intraciliary anterograde transport | 2 | CLUAP1,IFT52 | 18 | 0.2048161 |
| GO:BP | GO:0042157 | lipoprotein metabolic process | 2 | LYPLA2,PIGC | 116 | 0.2048161 |
| GO:BP | GO:0031065 | positive regulation of histone deacetylation | 2 | PML,CTBP1 | 15 | 0.2048161 |
| GO:BP | GO:1905664 | regulation of calcium ion import across plasma membrane | 2 | PPP3CB,PPP3CC | 8 | 0.2048161 |
| GO:BP | GO:0140157 | ammonium import across plasma membrane | 1 | SLC12A4 | 3 | 0.2048161 |
| GO:BP | GO:1905366 | negative regulation of intralumenal vesicle formation | 1 | RAB7A | 2 | 0.2048161 |
| GO:BP | GO:0051571 | positive regulation of histone H3-K4 methylation | 2 | PHF20,NELFA | 15 | 0.2049567 |
| GO:BP | GO:0099022 | vesicle tethering | 1 | TRAPPC3 | 32 | 0.2049567 |
| GO:BP | GO:0051338 | regulation of transferase activity | 17 | LMO4,DUSP12,ADORA1,AIDA,BUB3,SPINDOC,GSTP1,GSKIP,PML,WDR24,INCA1,PEX12,HEXIM1,RPTOR,CHMP6,FZR1,MAP2K7 | 663 | 0.2049567 |
| GO:BP | GO:0097435 | supramolecular fiber organization | 7 | ARHGEF10L,ASAP3,CCSAP,SYNPO2L,ANKRD1,BLOC1S2,ARFIP2 | 666 | 0.2049567 |
| GO:BP | GO:0043516 | regulation of DNA damage response, signal transduction by p53 class mediator | 2 | ANKRD1,KMT5A | 36 | 0.2049567 |
| GO:BP | GO:1904612 | response to 2,3,7,8-tetrachlorodibenzodioxine | 1 | SLC46A3 | 4 | 0.2057090 |
| GO:BP | GO:0034139 | regulation of toll-like receptor 3 signaling pathway | 1 | TRIM3 | 9 | 0.2057090 |
| GO:BP | GO:0098876 | vesicle-mediated transport to the plasma membrane | 8 | STX12,RAB3IP,RABEP1,EIPR1,ARFGEF2,RAB7A,RAB14,SNX12 | 140 | 0.2057090 |
| GO:BP | GO:0070922 | RISC complex assembly | 1 | CLP1 | 9 | 0.2057090 |
| GO:BP | GO:0070198 | protein localization to chromosome, telomeric region | 2 | PML,TERF2IP | 30 | 0.2057090 |
| GO:BP | GO:0098693 | regulation of synaptic vesicle cycle | 2 | DNAJC5,PRKAR1B | 13 | 0.2071142 |
| GO:BP | GO:0043506 | regulation of JUN kinase activity | 2 | AIDA,GSTP1 | 50 | 0.2071142 |
| GO:BP | GO:0080171 | lytic vacuole organization | 4 | PPP3CB,CHMP1A,HSD17B1,CHMP6 | 90 | 0.2071785 |
| GO:BP | GO:0033059 | cellular pigmentation | 4 | BLOC1S2,AP1M1,RAB1A,BBS7 | 58 | 0.2071785 |
| GO:BP | GO:1903429 | regulation of cell maturation | 2 | RAC3,BCL11A | 13 | 0.2071785 |
| GO:BP | GO:0007040 | lysosome organization | 4 | PPP3CB,CHMP1A,HSD17B1,CHMP6 | 90 | 0.2071785 |
| GO:BP | GO:0000963 | mitochondrial RNA processing | 2 | TRMT61B,METTL8 | 20 | 0.2071785 |
| GO:BP | GO:0006043 | glucosamine catabolic process | 1 | GNPDA2 | 2 | 0.2071785 |
| GO:BP | GO:0043622 | cortical microtubule organization | 1 | PAFAH1B1 | 4 | 0.2071785 |
| GO:BP | GO:0051303 | establishment of chromosome localization | 4 | BUB3,KAT5,CHMP1A,CHMP6 | 93 | 0.2071785 |
| GO:BP | GO:0048199 | vesicle targeting, to, from or within Golgi | 1 | TRAPPC3 | 31 | 0.2071785 |
| GO:BP | GO:0006297 | nucleotide-excision repair, DNA gap filling | 1 | LIG4 | 5 | 0.2073726 |
| GO:BP | GO:0051103 | DNA ligation involved in DNA repair | 1 | LIG4 | 5 | 0.2073726 |
| GO:BP | GO:0051877 | pigment granule aggregation in cell center | 1 | BBS7 | 2 | 0.2076697 |
| GO:BP | GO:1903929 | primary palate development | 1 | BBS7 | 2 | 0.2076697 |
| GO:BP | GO:0070670 | response to interleukin-4 | 2 | CDK4,PML | 24 | 0.2083894 |
| GO:BP | GO:0010835 | regulation of protein ADP-ribosylation | 1 | SPINDOC | 9 | 0.2092513 |
| GO:BP | GO:0051122 | hepoxilin biosynthetic process | 1 | GSTP1 | 4 | 0.2092513 |
| GO:BP | GO:0051121 | hepoxilin metabolic process | 1 | GSTP1 | 4 | 0.2092513 |
| GO:BP | GO:0051490 | negative regulation of filopodium assembly | 1 | RAB3IP | 6 | 0.2092513 |
| GO:BP | GO:0045739 | positive regulation of DNA repair | 7 | VPS72,KAT5,PIAS4,INO80D,SMARCB1,ACTL6A,UBE2V2 | 121 | 0.2101072 |
| GO:BP | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 3 | HDAC1,BRMS1,ING1 | 85 | 0.2101072 |
| GO:BP | GO:0070507 | regulation of microtubule cytoskeleton organization | 5 | CCSAP,NAV3,CHMP1A,PAFAH1B1,CHMP6 | 145 | 0.2104035 |
| GO:BP | GO:0007019 | microtubule depolymerization | 2 | CCSAP,NAV3 | 41 | 0.2104035 |
| GO:BP | GO:0030219 | megakaryocyte differentiation | 1 | PITHD1 | 44 | 0.2108493 |
| GO:BP | GO:0007023 | post-chaperonin tubulin folding pathway | 1 | TBCEL | 7 | 0.2115734 |
| GO:BP | GO:0035082 | axoneme assembly | 1 | CPLANE2 | 54 | 0.2115734 |
| GO:BP | GO:0060113 | inner ear receptor cell differentiation | 3 | TTC8,PAFAH1B1,MKS1 | 46 | 0.2120498 |
| GO:BP | GO:0000302 | response to reactive oxygen species | 1 | PEX14 | 163 | 0.2120498 |
| GO:BP | GO:0060382 | regulation of DNA strand elongation | 2 | INO80D,ACTL6A | 16 | 0.2120498 |
| GO:BP | GO:0015931 | nucleobase-containing compound transport | 8 | ADORA1,RAN,CASC3,SLC35B1,SRSF1,EIF4A3,RANBP2,SLC35C2 | 194 | 0.2120498 |
| GO:BP | GO:0050965 | detection of temperature stimulus involved in sensory perception of pain | 1 | ADORA1 | 9 | 0.2120498 |
| GO:BP | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1 | SDE2 | 17 | 0.2120498 |
| GO:BP | GO:0006427 | histidyl-tRNA aminoacylation | 1 | HARS2 | 2 | 0.2124872 |
| GO:BP | GO:1902389 | ceramide 1-phosphate transport | 1 | GLTP | 6 | 0.2127073 |
| GO:BP | GO:1902065 | response to L-glutamate | 2 | BCL11A,UFL1 | 11 | 0.2127073 |
| GO:BP | GO:0045687 | positive regulation of glial cell differentiation | 1 | HDAC1 | 28 | 0.2127073 |
| GO:BP | GO:0060155 | platelet dense granule organization | 2 | BLOC1S2,AP1M1 | 24 | 0.2127073 |
| GO:BP | GO:0018394 | peptidyl-lysine acetylation | 6 | VPS72,KAT5,PML,PHF20,ACTL6A,CTBP1 | 126 | 0.2127073 |
| GO:BP | GO:0021895 | cerebral cortex neuron differentiation | 2 | PAFAH1B1,RAC3 | 14 | 0.2127073 |
| GO:BP | GO:0051641 | cellular localization | 4 | ICMT,PEX14,PLEKHM2,CPLANE2 | 2819 | 0.2127073 |
| GO:BP | GO:0009637 | response to blue light | 1 | CRY1 | 3 | 0.2127073 |
| GO:BP | GO:0032364 | intracellular oxygen homeostasis | 1 | AQP11 | 7 | 0.2127073 |
| GO:BP | GO:1903894 | regulation of IRE1-mediated unfolded protein response | 2 | BAK1,UFL1 | 14 | 0.2127073 |
| GO:BP | GO:1904666 | regulation of ubiquitin protein ligase activity | 2 | PEX12,FZR1 | 22 | 0.2127073 |
| GO:BP | GO:0051647 | nucleus localization | 2 | LMNA,PAFAH1B1 | 30 | 0.2127073 |
| GO:BP | GO:0006520 | amino acid metabolic process | 1 | ICMT | 222 | 0.2127073 |
| GO:BP | GO:0003299 | muscle hypertrophy in response to stress | 1 | LMNA | 22 | 0.2127073 |
| GO:BP | GO:0048670 | regulation of collateral sprouting | 2 | BDNF,BCL11A | 19 | 0.2127073 |
| GO:BP | GO:0045911 | positive regulation of DNA recombination | 2 | VPS72,KAT5 | 56 | 0.2127073 |
| GO:BP | GO:0043393 | regulation of protein binding | 1 | PEX14 | 173 | 0.2127073 |
| GO:BP | GO:0031124 | mRNA 3’-end processing | 2 | CLP1,PCF11 | 50 | 0.2127073 |
| GO:BP | GO:0014887 | cardiac muscle adaptation | 1 | LMNA | 22 | 0.2127073 |
| GO:BP | GO:0048713 | regulation of oligodendrocyte differentiation | 1 | HDAC1 | 25 | 0.2127073 |
| GO:BP | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway | 1 | CRY1 | 5 | 0.2127073 |
| GO:BP | GO:1901701 | cellular response to oxygen-containing compound | 2 | PEX14,AGTRAP | 892 | 0.2127073 |
| GO:BP | GO:0014898 | cardiac muscle hypertrophy in response to stress | 1 | LMNA | 22 | 0.2127073 |
| GO:BP | GO:0051603 | proteolysis involved in protein catabolic process | 28 | PITHD1,RNF19B,HERC4,TRIM3,VPS37C,KAT5,AQP11,UBAC2,TRIP4,PML,CHMP1A,PEX12,OSBPL7,SPOP,CHMP6,FZR1,STAM2,PSMD14,NSFL1C,ASCC2,MKRN2,BBS7,UFL1,FBXL4,PSMB1,RNF216,TMEM168,PHF20L1 | 712 | 0.2127073 |
| GO:BP | GO:0002352 | B cell negative selection | 1 | BAK1 | 2 | 0.2127073 |
| GO:BP | GO:0006325 | chromatin organization | 23 | HDAC1,VPS72,LMNA,SUV39H2,NPM3,KAT5,RBM14,EMSY,KMT5A,ING1,BAHD1,MIER2,MTA3,METTL8,INO80D,PHF20,N6AMT1,SMARCB1,PICK1,ACTL6A,CTBP1,NAP1L5,SMARCAD1 | 633 | 0.2127863 |
| GO:BP | GO:0032057 | negative regulation of translational initiation in response to stress | 1 | PML | 5 | 0.2129686 |
| GO:BP | GO:1904353 | regulation of telomere capping | 2 | ERCC4,MAP2K7 | 23 | 0.2129686 |
| GO:BP | GO:0032055 | negative regulation of translation in response to stress | 1 | PML | 5 | 0.2129686 |
| GO:BP | GO:0022410 | circadian sleep/wake cycle process | 1 | ADORA1 | 10 | 0.2142057 |
| GO:BP | GO:0042749 | regulation of circadian sleep/wake cycle | 1 | ADORA1 | 10 | 0.2142057 |
| GO:BP | GO:0046503 | glycerolipid catabolic process | 1 | LYPLA2 | 39 | 0.2143351 |
| GO:BP | GO:0140718 | facultative heterochromatin formation | 1 | HDAC1 | 35 | 0.2143351 |
| GO:BP | GO:0006415 | translational termination | 1 | JMJD4 | 17 | 0.2143351 |
| GO:BP | GO:0030705 | cytoskeleton-dependent intracellular transport | 1 | PEX14 | 195 | 0.2143351 |
| GO:BP | GO:0010469 | regulation of signaling receptor activity | 2 | HDAC1,ADORA1 | 97 | 0.2146812 |
| GO:BP | GO:0072666 | establishment of protein localization to vacuole | 4 | VPS37C,STAM2,RAB7A,ZFYVE16 | 56 | 0.2153167 |
| GO:BP | GO:0014043 | negative regulation of neuron maturation | 1 | BCL11A | 2 | 0.2153167 |
| GO:BP | GO:0099111 | microtubule-based transport | 1 | PEX14 | 192 | 0.2153167 |
| GO:BP | GO:0002332 | transitional stage B cell differentiation | 1 | TRAF3IP2 | 2 | 0.2153167 |
| GO:BP | GO:1903008 | organelle disassembly | 7 | ARFIP2,KAT5,TRIP4,ASCC2,PARL,UFL1,FBXL4 | 141 | 0.2153167 |
| GO:BP | GO:1902410 | mitotic cytokinetic process | 2 | CHMP1A,CHMP6 | 26 | 0.2153167 |
| GO:BP | GO:0006790 | sulfur compound metabolic process | 1 | ICMT | 248 | 0.2153167 |
| GO:BP | GO:0051036 | regulation of endosome size | 1 | BLOC1S2 | 13 | 0.2153167 |
| GO:BP | GO:0008637 | apoptotic mitochondrial changes | 3 | LMNA,BLOC1S2,TRIAP1 | 90 | 0.2154854 |
| GO:BP | GO:0006170 | dAMP biosynthetic process | 1 | DGUOK | 3 | 0.2162919 |
| GO:BP | GO:0106383 | dAMP salvage | 1 | DGUOK | 3 | 0.2162919 |
| GO:BP | GO:0009171 | purine deoxyribonucleoside monophosphate biosynthetic process | 1 | DGUOK | 3 | 0.2162919 |
| GO:BP | GO:0008630 | intrinsic apoptotic signaling pathway in response to DNA damage | 4 | RAD9A,TRIAP1,PML,PIAS4 | 94 | 0.2162919 |
| GO:BP | GO:0106381 | purine deoxyribonucleotide salvage | 1 | DGUOK | 3 | 0.2162919 |
| GO:BP | GO:0051030 | snRNA transport | 1 | RAN | 6 | 0.2162919 |
| GO:BP | GO:0035726 | common myeloid progenitor cell proliferation | 1 | GSTP1 | 6 | 0.2162919 |
| GO:BP | GO:0032259 | methylation | 1 | ICMT | 286 | 0.2162919 |
| GO:BP | GO:0046070 | dGTP metabolic process | 1 | DGUOK | 3 | 0.2162919 |
| GO:BP | GO:0120035 | regulation of plasma membrane bounded cell projection organization | 1 | WRAP73 | 528 | 0.2166495 |
| GO:BP | GO:0046907 | intracellular transport | 2 | ICMT,PEX14 | 1439 | 0.2167838 |
| GO:BP | GO:0044778 | meiotic DNA integrity checkpoint signaling | 1 | HUS1 | 1 | 0.2169797 |
| GO:BP | GO:0014048 | regulation of glutamate secretion | 1 | ADORA1 | 9 | 0.2178722 |
| GO:BP | GO:0000012 | single strand break repair | 2 | LIG4,APTX | 10 | 0.2181396 |
| GO:BP | GO:0006901 | vesicle coating | 1 | TRAPPC3 | 36 | 0.2183342 |
| GO:BP | GO:0030091 | protein repair | 1 | MSRB3 | 7 | 0.2190638 |
| GO:BP | GO:0031344 | regulation of cell projection organization | 1 | WRAP73 | 541 | 0.2195881 |
| GO:BP | GO:0000154 | rRNA modification | 3 | NSUN4,TRMT61B,NSUN5 | 33 | 0.2195881 |
| GO:BP | GO:0033344 | cholesterol efflux | 1 | STX12 | 41 | 0.2195881 |
| GO:BP | GO:0010508 | positive regulation of autophagy | 4 | KAT5,PAFAH1B2,TBK1,WDR24 | 134 | 0.2195881 |
| GO:BP | GO:0000959 | mitochondrial RNA metabolic process | 3 | TEFM,TRMT61B,METTL8 | 51 | 0.2195881 |
| GO:BP | GO:1904356 | regulation of telomere maintenance via telomere lengthening | 3 | PML,ERCC4,MAP2K7 | 57 | 0.2195881 |
| GO:BP | GO:0097680 | double-strand break repair via classical nonhomologous end joining | 1 | LIG4 | 6 | 0.2212436 |
| GO:BP | GO:1905857 | positive regulation of pentose-phosphate shunt | 1 | RPTOR | 4 | 0.2212436 |
| GO:BP | GO:0051569 | regulation of histone H3-K4 methylation | 2 | PHF20,NELFA | 17 | 0.2213770 |
| GO:BP | GO:0009416 | response to light stimulus | 9 | SDE2,PPP1CA,CRY1,TRIAP1,PML,ERCC4,MAP2K7,RDH13,MAP4K3 | 240 | 0.2214044 |
| GO:BP | GO:0006851 | mitochondrial calcium ion transmembrane transport | 1 | PSEN2 | 18 | 0.2218637 |
| GO:BP | GO:0030521 | androgen receptor signaling pathway | 1 | HDAC1 | 41 | 0.2220847 |
| GO:BP | GO:0048147 | negative regulation of fibroblast proliferation | 2 | GSTP1,INCA1 | 31 | 0.2220847 |
| GO:BP | GO:0006414 | translational elongation | 4 | TRIP4,EFL1,EIF4A3,ASCC2 | 71 | 0.2220847 |
| GO:BP | GO:0039534 | negative regulation of MDA-5 signaling pathway | 1 | RIOK3 | 3 | 0.2227029 |
| GO:BP | GO:0032058 | positive regulation of translational initiation in response to stress | 1 | IMPACT | 4 | 0.2227029 |
| GO:BP | GO:2000279 | negative regulation of DNA biosynthetic process | 2 | ANKRD1,PML | 34 | 0.2227029 |
| GO:BP | GO:0051930 | regulation of sensory perception of pain | 1 | ADORA1 | 8 | 0.2227029 |
| GO:BP | GO:0042745 | circadian sleep/wake cycle | 1 | ADORA1 | 11 | 0.2227029 |
| GO:BP | GO:0140469 | GCN2-mediated signaling | 1 | IMPACT | 4 | 0.2227029 |
| GO:BP | GO:0051931 | regulation of sensory perception | 1 | ADORA1 | 8 | 0.2227029 |
| GO:BP | GO:2000322 | regulation of glucocorticoid receptor signaling pathway | 1 | CRY1 | 6 | 0.2244009 |
| GO:BP | GO:0031397 | negative regulation of protein ubiquitination | 3 | BUB3,CRY1,NXN | 76 | 0.2244384 |
| GO:BP | GO:0031333 | negative regulation of protein-containing complex assembly | 2 | LMO4,AIDA | 125 | 0.2244384 |
| GO:BP | GO:0051489 | regulation of filopodium assembly | 2 | ARAP1,RAB3IP | 44 | 0.2245812 |
| GO:BP | GO:0046604 | positive regulation of mitotic centrosome separation | 1 | NSFL1C | 3 | 0.2249941 |
| GO:BP | GO:0033673 | negative regulation of kinase activity | 6 | AIDA,GSTP1,GSKIP,INCA1,HEXIM1,CHMP6 | 191 | 0.2251900 |
| GO:BP | GO:0034644 | cellular response to UV | 3 | SDE2,TRIAP1,ERCC4 | 85 | 0.2251900 |
| GO:BP | GO:1902174 | positive regulation of keratinocyte apoptotic process | 1 | PIAS4 | 3 | 0.2251900 |
| GO:BP | GO:0090387 | phagolysosome assembly involved in apoptotic cell clearance | 1 | RAB14 | 2 | 0.2251900 |
| GO:BP | GO:0006612 | protein targeting to membrane | 1 | ICMT | 122 | 0.2251900 |
| GO:BP | GO:0046836 | glycolipid transport | 1 | GLTP | 7 | 0.2251900 |
| GO:BP | GO:0009628 | response to abiotic stimulus | 10 | AGTRAP,LMNA,ADORA1,SDE2,PSEN2,SUV39H2,ANKRD1,KAT5,RAD9A,PPP1CA | 847 | 0.2251900 |
| GO:BP | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1 | PPP1CA | 10 | 0.2251900 |
| GO:BP | GO:0042490 | mechanoreceptor differentiation | 3 | TTC8,PAFAH1B1,MKS1 | 48 | 0.2251900 |
| GO:BP | GO:0090386 | phagosome maturation involved in apoptotic cell clearance | 1 | RAB14 | 2 | 0.2251900 |
| GO:BP | GO:2000479 | regulation of cAMP-dependent protein kinase activity | 2 | SPATC1L,PRKAR1B | 14 | 0.2254189 |
| GO:BP | GO:0033363 | secretory granule organization | 3 | BLOC1S2,PAFAH1B1,AP1M1 | 51 | 0.2256461 |
| GO:BP | GO:0030431 | sleep | 1 | ADORA1 | 10 | 0.2256461 |
| GO:BP | GO:0003085 | negative regulation of systemic arterial blood pressure | 1 | ADORA1 | 14 | 0.2256461 |
| GO:BP | GO:0002793 | positive regulation of peptide secretion | 2 | ADORA1,PPP3CB | 73 | 0.2256461 |
| GO:BP | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore | 1 | KAT5 | 11 | 0.2256461 |
| GO:BP | GO:0007176 | regulation of epidermal growth factor-activated receptor activity | 2 | ADORA1,CHMP6 | 24 | 0.2256461 |
| GO:BP | GO:0001881 | receptor recycling | 3 | ARAP1,PEX12,ARFGEF2 | 43 | 0.2256461 |
| GO:BP | GO:0098801 | regulation of renal system process | 1 | ADORA1 | 16 | 0.2256461 |
| GO:BP | GO:0050961 | detection of temperature stimulus involved in sensory perception | 1 | ADORA1 | 11 | 0.2256461 |
| GO:BP | GO:0001778 | plasma membrane repair | 2 | CHMP1A,CHMP6 | 27 | 0.2256461 |
| GO:BP | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 17 | RNF19B,TRIM3,KAT5,TRIP4,PML,PEX12,SPOP,FZR1,PSMD14,NSFL1C,ASCC2,BBS7,UFL1,FBXL4,PSMB1,RNF216,PHF20L1 | 420 | 0.2256461 |
| GO:BP | GO:0032515 | negative regulation of phosphoprotein phosphatase activity | 1 | TIPRL | 20 | 0.2256461 |
| GO:BP | GO:0090114 | COPII-coated vesicle budding | 1 | TRAPPC3 | 40 | 0.2262648 |
| GO:BP | GO:2000642 | negative regulation of early endosome to late endosome transport | 1 | SNX12 | 2 | 0.2262933 |
| GO:BP | GO:1902339 | positive regulation of apoptotic process involved in morphogenesis | 1 | PML | 5 | 0.2273843 |
| GO:BP | GO:0006432 | phenylalanyl-tRNA aminoacylation | 1 | FARSA | 4 | 0.2273843 |
| GO:BP | GO:0048278 | vesicle docking | 1 | STX12 | 54 | 0.2273843 |
| GO:BP | GO:0071362 | cellular response to ether | 1 | CDK4 | 5 | 0.2273843 |
| GO:BP | GO:0019083 | viral transcription | 1 | HDAC1 | 48 | 0.2273843 |
| GO:BP | GO:1904747 | positive regulation of apoptotic process involved in development | 1 | PML | 5 | 0.2273843 |
| GO:BP | GO:0034599 | cellular response to oxidative stress | 1 | PEX14 | 217 | 0.2273843 |
| GO:BP | GO:0030578 | PML body organization | 1 | PML | 6 | 0.2273843 |
| GO:BP | GO:0009894 | regulation of catabolic process | 19 | PITHD1,RNF19B,ADORA1,POLR2G,KAT5,PPP1CA,AQP11,PAFAH1B2,CDK4,TBK1,PML,WDR24,ERCC4,CASC3,OSBPL7,EIF4A3,RPTOR,CHMP6,FZR1 | 883 | 0.2273843 |
| GO:BP | GO:0090402 | oncogene-induced cell senescence | 1 | PML | 5 | 0.2273843 |
| GO:BP | GO:0008217 | regulation of blood pressure | 1 | AGTRAP | 114 | 0.2273843 |
| GO:BP | GO:2000736 | regulation of stem cell differentiation | 2 | HDAC1,KAT5 | 71 | 0.2273843 |
| GO:BP | GO:0097485 | neuron projection guidance | 2 | LYPLA2,LMO4 | 177 | 0.2276166 |
| GO:BP | GO:0001736 | establishment of planar polarity | 3 | TTC8,PAFAH1B1,MKS1 | 70 | 0.2276166 |
| GO:BP | GO:0099179 | regulation of synaptic membrane adhesion | 1 | LRFN3 | 4 | 0.2276166 |
| GO:BP | GO:0000055 | ribosomal large subunit export from nucleus | 1 | RAN | 7 | 0.2276166 |
| GO:BP | GO:0051252 | regulation of RNA metabolic process | 68 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,ING1,BRF1,BAHD1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,CASC3,HEXIM1,SRSF1,INTS2,EIF4A3,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,ZNF638 | 2826 | 0.2276166 |
| GO:BP | GO:1901387 | positive regulation of voltage-gated calcium channel activity | 1 | PPP3CB | 12 | 0.2276166 |
| GO:BP | GO:0048665 | neuron fate specification | 1 | LMO4 | 13 | 0.2276166 |
| GO:BP | GO:1901568 | fatty acid derivative metabolic process | 1 | LYPLA2 | 49 | 0.2276166 |
| GO:BP | GO:0015791 | polyol transmembrane transport | 1 | AQP11 | 6 | 0.2276166 |
| GO:BP | GO:0001578 | microtubule bundle formation | 1 | CPLANE2 | 79 | 0.2276166 |
| GO:BP | GO:0001946 | lymphangiogenesis | 1 | PPP3CB | 12 | 0.2276166 |
| GO:BP | GO:0030036 | actin cytoskeleton organization | 2 | ARHGEF10L,ASAP3 | 566 | 0.2276166 |
| GO:BP | GO:0007030 | Golgi organization | 1 | PLEKHM2 | 133 | 0.2276166 |
| GO:BP | GO:0010614 | negative regulation of cardiac muscle hypertrophy | 1 | LMNA | 25 | 0.2276166 |
| GO:BP | GO:0034244 | negative regulation of transcription elongation by RNA polymerase II | 2 | HEXIM1,NELFA | 18 | 0.2276166 |
| GO:BP | GO:0034250 | positive regulation of amide metabolic process | 6 | JMJD4,POLR2G,RPS6KB1,EIF4A3,IMPACT,METTL8 | 150 | 0.2276166 |
| GO:BP | GO:1902661 | positive regulation of glucose mediated signaling pathway | 1 | SMARCB1 | 3 | 0.2276166 |
| GO:BP | GO:0045663 | positive regulation of myoblast differentiation | 3 | KAT5,SMARCB1,ACTL6A | 36 | 0.2276166 |
| GO:BP | GO:1902659 | regulation of glucose mediated signaling pathway | 1 | SMARCB1 | 3 | 0.2276166 |
| GO:BP | GO:0035434 | copper ion transmembrane transport | 1 | SLC46A3 | 7 | 0.2276166 |
| GO:BP | GO:0006359 | regulation of transcription by RNA polymerase III | 2 | BRF1,RPTOR | 30 | 0.2276166 |
| GO:BP | GO:0007418 | ventral midline development | 1 | CLUAP1 | 4 | 0.2276166 |
| GO:BP | GO:0042256 | cytosolic ribosome assembly | 1 | EFL1 | 5 | 0.2276166 |
| GO:BP | GO:0007411 | axon guidance | 2 | LYPLA2,LMO4 | 177 | 0.2276166 |
| GO:BP | GO:0072014 | proximal tubule development | 1 | AQP11 | 8 | 0.2276166 |
| GO:BP | GO:0007164 | establishment of tissue polarity | 3 | TTC8,PAFAH1B1,MKS1 | 70 | 0.2276166 |
| GO:BP | GO:0045936 | negative regulation of phosphate metabolic process | 9 | TIPRL,AIDA,GSTP1,GSKIP,TERF2IP,INCA1,HEXIM1,CHMP6,IMPACT | 334 | 0.2276166 |
| GO:BP | GO:0038180 | nerve growth factor signaling pathway | 1 | BDNF | 11 | 0.2276166 |
| GO:BP | GO:0071709 | membrane assembly | 4 | CHMP1A,CHMP6,NSFL1C,REEP4 | 54 | 0.2276166 |
| GO:BP | GO:1903083 | protein localization to condensed chromosome | 1 | BUB3 | 15 | 0.2295941 |
| GO:BP | GO:0034501 | protein localization to kinetochore | 1 | BUB3 | 15 | 0.2295941 |
| GO:BP | GO:0010563 | negative regulation of phosphorus metabolic process | 9 | TIPRL,AIDA,GSTP1,GSKIP,TERF2IP,INCA1,HEXIM1,CHMP6,IMPACT | 335 | 0.2298051 |
| GO:BP | GO:0032891 | negative regulation of organic acid transport | 1 | ADORA1 | 18 | 0.2321933 |
| GO:BP | GO:0003071 | renal system process involved in regulation of systemic arterial blood pressure | 1 | ADORA1 | 13 | 0.2321933 |
| GO:BP | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation | 1 | CLP1 | 13 | 0.2323644 |
| GO:BP | GO:0030071 | regulation of mitotic metaphase/anaphase transition | 5 | BUB3,SMARCB1,ACTL6A,RIOK2,MAD1L1 | 87 | 0.2330791 |
| GO:BP | GO:0061009 | common bile duct development | 1 | MKS1 | 4 | 0.2331604 |
| GO:BP | GO:0072595 | maintenance of protein localization in organelle | 2 | PML,ARL2BP | 38 | 0.2345282 |
| GO:BP | GO:0042176 | regulation of protein catabolic process | 2 | PITHD1,RNF19B | 328 | 0.2348313 |
| GO:BP | GO:0070291 | N-acylethanolamine metabolic process | 1 | GDPD1 | 4 | 0.2352673 |
| GO:BP | GO:0014741 | negative regulation of muscle hypertrophy | 1 | LMNA | 26 | 0.2358539 |
| GO:BP | GO:0003007 | heart morphogenesis | 3 | CPLANE2,SYNPO2L,ANKRD1 | 217 | 0.2358539 |
| GO:BP | GO:0042326 | negative regulation of phosphorylation | 8 | AIDA,GSTP1,GSKIP,TERF2IP,INCA1,HEXIM1,CHMP6,IMPACT | 290 | 0.2359653 |
| GO:BP | GO:0010826 | negative regulation of centrosome duplication | 1 | RBM14 | 12 | 0.2361606 |
| GO:BP | GO:0046606 | negative regulation of centrosome cycle | 1 | RBM14 | 12 | 0.2361606 |
| GO:BP | GO:0042551 | neuron maturation | 3 | RAC3,BCL11A,PICK1 | 35 | 0.2361606 |
| GO:BP | GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 1 | POLR2G | 13 | 0.2367189 |
| GO:BP | GO:0043576 | regulation of respiratory gaseous exchange | 1 | ADORA1 | 15 | 0.2377486 |
| GO:BP | GO:0016048 | detection of temperature stimulus | 1 | ADORA1 | 12 | 0.2377486 |
| GO:BP | GO:0006661 | phosphatidylinositol biosynthetic process | 2 | PIGC,IPMK | 117 | 0.2378370 |
| GO:BP | GO:1901264 | carbohydrate derivative transport | 4 | ADORA1,GLTP,SLC35B1,SLC35C2 | 68 | 0.2378491 |
| GO:BP | GO:1904627 | response to phorbol 13-acetate 12-myristate | 1 | CDK4 | 4 | 0.2379327 |
| GO:BP | GO:1904628 | cellular response to phorbol 13-acetate 12-myristate | 1 | CDK4 | 4 | 0.2379327 |
| GO:BP | GO:0031573 | mitotic intra-S DNA damage checkpoint signaling | 2 | RAD9A,HUS1 | 15 | 0.2381852 |
| GO:BP | GO:0045893 | positive regulation of DNA-templated transcription | 24 | PITHD1,HDAC1,MED8,LMO4,VPS72,ECD,PPP3CB,ANKRD1,BLOC1S2,KAT5,RBM14,MED17,ANKRD49,TBK1,TRIAP1,GTF2F2,ING1,BRF1,TRIP4,PML,ARL2BP,E2F4,ZFP90,ZNF287 | 1295 | 0.2381852 |
| GO:BP | GO:0071456 | cellular response to hypoxia | 2 | LMNA,SUV39H2 | 121 | 0.2381852 |
| GO:BP | GO:0070901 | mitochondrial tRNA methylation | 1 | TRMT61B | 4 | 0.2381852 |
| GO:BP | GO:0006046 | N-acetylglucosamine catabolic process | 1 | GNPDA2 | 3 | 0.2387477 |
| GO:BP | GO:0006041 | glucosamine metabolic process | 1 | GNPDA2 | 3 | 0.2387477 |
| GO:BP | GO:0042733 | embryonic digit morphogenesis | 1 | HDAC1 | 50 | 0.2388525 |
| GO:BP | GO:0140650 | radial glia-guided pyramidal neuron migration | 1 | PAFAH1B1 | 4 | 0.2388525 |
| GO:BP | GO:0021540 | corpus callosum morphogenesis | 1 | PAFAH1B1 | 6 | 0.2388525 |
| GO:BP | GO:0007021 | tubulin complex assembly | 1 | TBCEL | 10 | 0.2388525 |
| GO:BP | GO:0045900 | negative regulation of translational elongation | 1 | EIF4A3 | 5 | 0.2388525 |
| GO:BP | GO:0051661 | maintenance of centrosome location | 1 | PAFAH1B1 | 6 | 0.2388525 |
| GO:BP | GO:1904415 | regulation of xenophagy | 1 | TBK1 | 7 | 0.2394246 |
| GO:BP | GO:1904417 | positive regulation of xenophagy | 1 | TBK1 | 7 | 0.2394246 |
| GO:BP | GO:0000394 | RNA splicing, via endonucleolytic cleavage and ligation | 1 | CLP1 | 14 | 0.2395727 |
| GO:BP | GO:0032462 | regulation of protein homooligomerization | 1 | BCL11A | 4 | 0.2395727 |
| GO:BP | GO:0006266 | DNA ligation | 2 | LIG4,APTX | 16 | 0.2395727 |
| GO:BP | GO:1903860 | negative regulation of dendrite extension | 1 | BCL11A | 3 | 0.2395727 |
| GO:BP | GO:1900242 | regulation of synaptic vesicle endocytosis | 1 | PPP3CB | 16 | 0.2395727 |
| GO:BP | GO:1901386 | negative regulation of voltage-gated calcium channel activity | 1 | PPP3CB | 14 | 0.2395727 |
| GO:BP | GO:0006355 | regulation of DNA-templated transcription | 62 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,ZNF195,ZNF408,SPINDOC,KAT5,BRMS1,RBM14,EMSY,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,ING1,BRF1,BAHD1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,HEXIM1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,MTA3,BCL11A | 2562 | 0.2395727 |
| GO:BP | GO:0097193 | intrinsic apoptotic signaling pathway | 6 | HDAC1,RAD9A,TRIAP1,DIABLO,GSKIP,PML | 272 | 0.2395727 |
| GO:BP | GO:0014047 | glutamate secretion | 1 | ADORA1 | 15 | 0.2400165 |
| GO:BP | GO:0010867 | positive regulation of triglyceride biosynthetic process | 1 | KAT5 | 13 | 0.2400165 |
| GO:BP | GO:0031109 | microtubule polymerization or depolymerization | 3 | CCSAP,BLOC1S2,NAV3 | 119 | 0.2418363 |
| GO:BP | GO:1902680 | positive regulation of RNA biosynthetic process | 24 | PITHD1,HDAC1,MED8,LMO4,VPS72,ECD,PPP3CB,ANKRD1,BLOC1S2,KAT5,RBM14,MED17,ANKRD49,TBK1,TRIAP1,GTF2F2,ING1,BRF1,TRIP4,PML,ARL2BP,E2F4,ZFP90,ZNF287 | 1302 | 0.2419145 |
| GO:BP | GO:0006511 | ubiquitin-dependent protein catabolic process | 24 | RNF19B,HERC4,TRIM3,VPS37C,KAT5,TRIP4,PML,CHMP1A,PEX12,SPOP,CHMP6,FZR1,STAM2,PSMD14,NSFL1C,ASCC2,MKRN2,BBS7,UFL1,FBXL4,PSMB1,RNF216,TMEM168,PHF20L1 | 618 | 0.2431429 |
| GO:BP | GO:0120009 | intermembrane lipid transfer | 2 | GLTP,TRIAP1 | 40 | 0.2431429 |
| GO:BP | GO:0016573 | histone acetylation | 6 | VPS72,KAT5,PHF20,ACTL6A,CTBP1,PHF20L1 | 110 | 0.2433373 |
| GO:BP | GO:0099517 | synaptic vesicle transport along microtubule | 1 | BLOC1S2 | 15 | 0.2444042 |
| GO:BP | GO:0048490 | anterograde synaptic vesicle transport | 1 | BLOC1S2 | 15 | 0.2444042 |
| GO:BP | GO:0099514 | synaptic vesicle cytoskeletal transport | 1 | BLOC1S2 | 15 | 0.2444042 |
| GO:BP | GO:0010832 | negative regulation of myotube differentiation | 1 | BDNF | 10 | 0.2450183 |
| GO:BP | GO:0050995 | negative regulation of lipid catabolic process | 1 | ADORA1 | 14 | 0.2455053 |
| GO:BP | GO:0050996 | positive regulation of lipid catabolic process | 1 | ADORA1 | 15 | 0.2455053 |
| GO:BP | GO:1905784 | regulation of anaphase-promoting complex-dependent catabolic process | 1 | FZR1 | 4 | 0.2455053 |
| GO:BP | GO:0062149 | detection of stimulus involved in sensory perception of pain | 1 | ADORA1 | 14 | 0.2455053 |
| GO:BP | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator | 1 | ANKRD1 | 16 | 0.2455903 |
| GO:BP | GO:0045639 | positive regulation of myeloid cell differentiation | 1 | PITHD1 | 66 | 0.2455903 |
| GO:BP | GO:1902099 | regulation of metaphase/anaphase transition of cell cycle | 5 | BUB3,SMARCB1,ACTL6A,RIOK2,MAD1L1 | 88 | 0.2459410 |
| GO:BP | GO:0034497 | protein localization to phagophore assembly site | 1 | ARFIP2 | 16 | 0.2459410 |
| GO:BP | GO:1901020 | negative regulation of calcium ion transmembrane transporter activity | 3 | PPP3CB,SRI,PPP3CC | 28 | 0.2462417 |
| GO:BP | GO:0050994 | regulation of lipid catabolic process | 2 | ADORA1,CDK4 | 37 | 0.2462417 |
| GO:BP | GO:0033152 | immunoglobulin V(D)J recombination | 1 | LIG4 | 8 | 0.2462417 |
| GO:BP | GO:0001510 | RNA methylation | 5 | NSUN4,TRMT61B,METTL8,MTO1,NSUN5 | 89 | 0.2462417 |
| GO:BP | GO:0044790 | suppression of viral release by host | 2 | PML,TRIM35 | 16 | 0.2462417 |
| GO:BP | GO:0007004 | telomere maintenance via telomerase | 3 | PML,TERF2IP,MAP2K7 | 63 | 0.2462417 |
| GO:BP | GO:0002443 | leukocyte mediated immunity | 2 | PLEKHM2,RNF19B | 196 | 0.2462417 |
| GO:BP | GO:0006420 | arginyl-tRNA aminoacylation | 1 | RARS1 | 3 | 0.2462417 |
| GO:BP | GO:0043086 | negative regulation of catalytic activity | 11 | TIPRL,AIDA,BUB3,GSTP1,TRIAP1,TTC8,GSKIP,PML,INCA1,NLE1,HEXIM1 | 456 | 0.2462417 |
| GO:BP | GO:0006418 | tRNA aminoacylation for protein translation | 3 | FARSA,HARS2,RARS1 | 40 | 0.2468670 |
| GO:BP | GO:0015886 | heme transport | 1 | SLC48A1 | 9 | 0.2471562 |
| GO:BP | GO:0090311 | regulation of protein deacetylation | 3 | BRMS1,PML,CTBP1 | 44 | 0.2477793 |
| GO:BP | GO:0060828 | regulation of canonical Wnt signaling pathway | 6 | HDAC1,PPP1CA,UBAC2,GSKIP,NLE1,MKS1 | 213 | 0.2477793 |
| GO:BP | GO:0010464 | regulation of mesenchymal cell proliferation | 1 | LMNA | 26 | 0.2485753 |
| GO:BP | GO:0050951 | sensory perception of temperature stimulus | 1 | ADORA1 | 12 | 0.2485753 |
| GO:BP | GO:0009127 | purine nucleoside monophosphate biosynthetic process | 2 | DGUOK,PAICS | 20 | 0.2485753 |
| GO:BP | GO:0010046 | response to mycotoxin | 1 | BAK1 | 3 | 0.2485753 |
| GO:BP | GO:0062197 | cellular response to chemical stress | 1 | PEX14 | 268 | 0.2485753 |
| GO:BP | GO:0000076 | DNA replication checkpoint signaling | 2 | RAD9A,HUS1 | 16 | 0.2485753 |
| GO:BP | GO:0003094 | glomerular filtration | 1 | ADORA1 | 20 | 0.2485753 |
| GO:BP | GO:0051953 | negative regulation of amine transport | 1 | ADORA1 | 16 | 0.2485753 |
| GO:BP | GO:0007091 | metaphase/anaphase transition of mitotic cell cycle | 5 | BUB3,SMARCB1,ACTL6A,RIOK2,MAD1L1 | 91 | 0.2489256 |
| GO:BP | GO:0051301 | cell division | 11 | SDE2,CCSAP,DCLRE1A,BUB3,PPP1CA,CDK4,KMT5A,RAN,LIG4,CHMP1A,PAFAH1B1 | 571 | 0.2489256 |
| GO:BP | GO:0097494 | regulation of vesicle size | 1 | BLOC1S2 | 19 | 0.2489256 |
| GO:BP | GO:0010927 | cellular component assembly involved in morphogenesis | 2 | SYNPO2L,ANKRD1 | 106 | 0.2489256 |
| GO:BP | GO:2000277 | positive regulation of oxidative phosphorylation uncoupler activity | 1 | PPARD | 3 | 0.2489256 |
| GO:BP | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2 | TRIAP1,PML | 43 | 0.2489256 |
| GO:BP | GO:0006278 | RNA-templated DNA biosynthetic process | 3 | PML,TERF2IP,MAP2K7 | 64 | 0.2495552 |
| GO:BP | GO:0014015 | positive regulation of gliogenesis | 1 | HDAC1 | 44 | 0.2498287 |
| GO:BP | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening | 1 | POLR2G | 15 | 0.2505307 |
| GO:BP | GO:0060122 | inner ear receptor cell stereocilium organization | 2 | TTC8,MKS1 | 23 | 0.2505307 |
| GO:BP | GO:0042796 | snRNA transcription by RNA polymerase III | 1 | SNAPC1 | 8 | 0.2505307 |
| GO:BP | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade | 1 | PPP3CB | 16 | 0.2505307 |
| GO:BP | GO:0032456 | endocytic recycling | 5 | STX12,EIPR1,RAB7A,RAB14,SNX12 | 79 | 0.2505307 |
| GO:BP | GO:0106058 | positive regulation of calcineurin-mediated signaling | 1 | PPP3CB | 16 | 0.2505307 |
| GO:BP | GO:0034502 | protein localization to chromosome | 4 | BUB3,PML,TERF2IP,PIAS4 | 101 | 0.2518669 |
| GO:BP | GO:1990959 | eosinophil homeostasis | 1 | TRAF3IP2 | 2 | 0.2518797 |
| GO:BP | GO:0002343 | peripheral B cell selection | 1 | TRAF3IP2 | 2 | 0.2518797 |
| GO:BP | GO:0036294 | cellular response to decreased oxygen levels | 2 | LMNA,SUV39H2 | 131 | 0.2518797 |
| GO:BP | GO:0018126 | protein hydroxylation | 1 | JMJD4 | 25 | 0.2518797 |
| GO:BP | GO:0002344 | B cell affinity maturation | 1 | TRAF3IP2 | 2 | 0.2518797 |
| GO:BP | GO:2001141 | regulation of RNA biosynthetic process | 62 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,ZNF195,ZNF408,SPINDOC,KAT5,BRMS1,RBM14,EMSY,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,ING1,BRF1,BAHD1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,HEXIM1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,MTA3,BCL11A | 2579 | 0.2518797 |
| GO:BP | GO:0035308 | negative regulation of protein dephosphorylation | 1 | TIPRL | 27 | 0.2518797 |
| GO:BP | GO:0031023 | microtubule organizing center organization | 4 | RBM14,E2F4,CHMP1A,PAFAH1B1 | 140 | 0.2518797 |
| GO:BP | GO:0042981 | regulation of apoptotic process | 12 | HDAC1,VPS72,LMNA,ADORA1,PSEN2,ANKRD1,BDNF,KAT5,BRMS1,RAD9A,PPP1CA,GSTP1 | 1093 | 0.2518797 |
| GO:BP | GO:0030029 | actin filament-based process | 2 | ARHGEF10L,ASAP3 | 643 | 0.2520646 |
| GO:BP | GO:1902426 | deactivation of mitotic spindle assembly checkpoint | 1 | MAD1L1 | 2 | 0.2533673 |
| GO:BP | GO:0090233 | negative regulation of spindle checkpoint | 1 | MAD1L1 | 2 | 0.2533673 |
| GO:BP | GO:0048633 | positive regulation of skeletal muscle tissue growth | 1 | RPS6KB1 | 6 | 0.2533673 |
| GO:BP | GO:0006895 | Golgi to endosome transport | 2 | MON2,RAB14 | 17 | 0.2533673 |
| GO:BP | GO:0140499 | negative regulation of mitotic spindle assembly checkpoint signaling | 1 | MAD1L1 | 2 | 0.2533673 |
| GO:BP | GO:0014732 | skeletal muscle atrophy | 1 | RPS6KB1 | 5 | 0.2533673 |
| GO:BP | GO:0044091 | membrane biogenesis | 4 | CHMP1A,CHMP6,NSFL1C,REEP4 | 59 | 0.2533673 |
| GO:BP | GO:0038026 | reelin-mediated signaling pathway | 1 | PAFAH1B1 | 7 | 0.2549501 |
| GO:BP | GO:0000492 | box C/D snoRNP assembly | 1 | NOPCHAP1 | 10 | 0.2557438 |
| GO:BP | GO:0097205 | renal filtration | 1 | ADORA1 | 22 | 0.2557438 |
| GO:BP | GO:0032785 | negative regulation of DNA-templated transcription, elongation | 2 | HEXIM1,NELFA | 21 | 0.2557438 |
| GO:BP | GO:0006506 | GPI anchor biosynthetic process | 1 | PIGC | 30 | 0.2557438 |
| GO:BP | GO:0034138 | toll-like receptor 3 signaling pathway | 1 | TRIM3 | 13 | 0.2557438 |
| GO:BP | GO:0036303 | lymph vessel morphogenesis | 1 | PPP3CB | 17 | 0.2557438 |
| GO:BP | GO:0018364 | peptidyl-glutamine methylation | 1 | N6AMT1 | 4 | 0.2561636 |
| GO:BP | GO:0019941 | modification-dependent protein catabolic process | 24 | RNF19B,HERC4,TRIM3,VPS37C,KAT5,TRIP4,PML,CHMP1A,PEX12,SPOP,CHMP6,FZR1,STAM2,PSMD14,NSFL1C,ASCC2,MKRN2,BBS7,UFL1,FBXL4,PSMB1,RNF216,TMEM168,PHF20L1 | 628 | 0.2561982 |
| GO:BP | GO:0072344 | rescue of stalled ribosome | 2 | TRIP4,ASCC2 | 22 | 0.2561982 |
| GO:BP | GO:0030307 | positive regulation of cell growth | 6 | BDNF,PAFAH1B1,RPTOR,BCL11A,N6AMT1,SMARCB1 | 132 | 0.2564362 |
| GO:BP | GO:2000849 | regulation of glucocorticoid secretion | 1 | CRY1 | 5 | 0.2564362 |
| GO:BP | GO:0072521 | purine-containing compound metabolic process | 1 | ICMT | 388 | 0.2564362 |
| GO:BP | GO:0021766 | hippocampus development | 3 | HDAC1,RAN,PAFAH1B1 | 70 | 0.2564362 |
| GO:BP | GO:0140245 | regulation of translation at postsynapse | 1 | EIF4A3 | 5 | 0.2570131 |
| GO:BP | GO:0033143 | regulation of intracellular steroid hormone receptor signaling pathway | 1 | HDAC1 | 60 | 0.2570131 |
| GO:BP | GO:0140243 | regulation of translation at synapse | 1 | EIF4A3 | 5 | 0.2570131 |
| GO:BP | GO:0030488 | tRNA methylation | 3 | TRMT61B,METTL8,MTO1 | 43 | 0.2570131 |
| GO:BP | GO:0010522 | regulation of calcium ion transport into cytosol | 2 | PML,BAK1 | 10 | 0.2570131 |
| GO:BP | GO:0009644 | response to high light intensity | 1 | RDH13 | 2 | 0.2570131 |
| GO:BP | GO:1904153 | negative regulation of retrograde protein transport, ER to cytosol | 1 | UBAC2 | 9 | 0.2570131 |
| GO:BP | GO:0090150 | establishment of protein localization to membrane | 1 | ICMT | 260 | 0.2570131 |
| GO:BP | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle | 2 | CDK4,MTA3 | 28 | 0.2570131 |
| GO:BP | GO:1903321 | negative regulation of protein modification by small protein conjugation or removal | 3 | BUB3,CRY1,NXN | 86 | 0.2570131 |
| GO:BP | GO:0043456 | regulation of pentose-phosphate shunt | 1 | RPTOR | 6 | 0.2577911 |
| GO:BP | GO:0001921 | positive regulation of receptor recycling | 1 | ARAP1 | 13 | 0.2582775 |
| GO:BP | GO:0006505 | GPI anchor metabolic process | 1 | PIGC | 31 | 0.2582775 |
| GO:BP | GO:0048668 | collateral sprouting | 2 | BDNF,BCL11A | 26 | 0.2582775 |
| GO:BP | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | 1 | NLE1 | 5 | 0.2583416 |
| GO:BP | GO:0034248 | regulation of amide metabolic process | 10 | JMJD4,TRIM3,POLR2G,PPP1CA,PML,CASC3,RPS6KB1,EIF4A3,RPTOR,IMPACT | 427 | 0.2583416 |
| GO:BP | GO:0061024 | membrane organization | 3 | CPLANE2,STX12,TRAPPC3 | 663 | 0.2588465 |
| GO:BP | GO:0051443 | positive regulation of ubiquitin-protein transferase activity | 2 | PEX12,FZR1 | 30 | 0.2588465 |
| GO:BP | GO:0016562 | protein import into peroxisome matrix, receptor recycling | 1 | PEX12 | 7 | 0.2588465 |
| GO:BP | GO:1904354 | negative regulation of telomere capping | 1 | ERCC4 | 8 | 0.2588465 |
| GO:BP | GO:0032402 | melanosome transport | 2 | RAB1A,BBS7 | 19 | 0.2588465 |
| GO:BP | GO:0044784 | metaphase/anaphase transition of cell cycle | 5 | BUB3,SMARCB1,ACTL6A,RIOK2,MAD1L1 | 92 | 0.2588465 |
| GO:BP | GO:0032623 | interleukin-2 production | 2 | KAT5,NAV3 | 31 | 0.2588465 |
| GO:BP | GO:0006900 | vesicle budding from membrane | 4 | TRAPPC3,CHMP6,RAB1A,RAB7A | 77 | 0.2588465 |
| GO:BP | GO:1902806 | regulation of cell cycle G1/S phase transition | 7 | SDE2,ECD,TRIAP1,PML,RPTOR,SMARCB1,ACTL6A | 164 | 0.2588465 |
| GO:BP | GO:0001911 | negative regulation of leukocyte mediated cytotoxicity | 1 | PPP3CB | 11 | 0.2588465 |
| GO:BP | GO:0032663 | regulation of interleukin-2 production | 2 | KAT5,NAV3 | 31 | 0.2588465 |
| GO:BP | GO:0098534 | centriole assembly | 2 | RBM14,E2F4 | 41 | 0.2588465 |
| GO:BP | GO:0051444 | negative regulation of ubiquitin-protein transferase activity | 1 | BUB3 | 18 | 0.2588493 |
| GO:BP | GO:0006623 | protein targeting to vacuole | 3 | VPS37C,RAB7A,ZFYVE16 | 43 | 0.2592622 |
| GO:BP | GO:0030261 | chromosome condensation | 2 | KMT5A,CHMP1A | 34 | 0.2597736 |
| GO:BP | GO:0045685 | regulation of glial cell differentiation | 1 | HDAC1 | 47 | 0.2606769 |
| GO:BP | GO:0098781 | ncRNA transcription | 6 | NPM3,SNAPC1,BRF1,GTF3C3,SMARCB1,PPARD | 118 | 0.2628303 |
| GO:BP | GO:0018026 | peptidyl-lysine monomethylation | 1 | KMT5A | 10 | 0.2628303 |
| GO:BP | GO:0048388 | endosomal lumen acidification | 1 | AQP11 | 13 | 0.2630234 |
| GO:BP | GO:1905232 | cellular response to L-glutamate | 1 | BCL11A | 4 | 0.2630234 |
| GO:BP | GO:0070262 | peptidyl-serine dephosphorylation | 1 | PPP1CA | 14 | 0.2630234 |
| GO:BP | GO:0045165 | cell fate commitment | 2 | HDAC1,LMO4 | 157 | 0.2636962 |
| GO:BP | GO:0010923 | negative regulation of phosphatase activity | 1 | TIPRL | 29 | 0.2636962 |
| GO:BP | GO:0044090 | positive regulation of vacuole organization | 1 | PPP3CB | 23 | 0.2636962 |
| GO:BP | GO:0018393 | internal peptidyl-lysine acetylation | 6 | VPS72,KAT5,PHF20,ACTL6A,CTBP1,PHF20L1 | 114 | 0.2636962 |
| GO:BP | GO:0006417 | regulation of translation | 9 | JMJD4,TRIM3,POLR2G,PPP1CA,PML,CASC3,RPS6KB1,EIF4A3,IMPACT | 374 | 0.2636962 |
| GO:BP | GO:0070676 | intralumenal vesicle formation | 1 | RAB7A | 4 | 0.2636962 |
| GO:BP | GO:0032930 | positive regulation of superoxide anion generation | 1 | GSTP1 | 7 | 0.2636962 |
| GO:BP | GO:0016191 | synaptic vesicle uncoating | 1 | SH3GL1 | 6 | 0.2636962 |
| GO:BP | GO:0043039 | tRNA aminoacylation | 3 | FARSA,HARS2,RARS1 | 43 | 0.2636962 |
| GO:BP | GO:0048538 | thymus development | 1 | LMO4 | 35 | 0.2636962 |
| GO:BP | GO:1903542 | negative regulation of exosomal secretion | 1 | RAB7A | 4 | 0.2636962 |
| GO:BP | GO:0120186 | negative regulation of protein localization to chromatin | 1 | PIAS4 | 5 | 0.2636962 |
| GO:BP | GO:0009153 | purine deoxyribonucleotide biosynthetic process | 1 | DGUOK | 4 | 0.2644199 |
| GO:BP | GO:0060292 | long-term synaptic depression | 1 | ADORA1 | 22 | 0.2644199 |
| GO:BP | GO:0045777 | positive regulation of blood pressure | 1 | ADORA1 | 15 | 0.2644199 |
| GO:BP | GO:0035590 | purinergic nucleotide receptor signaling pathway | 1 | ADORA1 | 15 | 0.2644199 |
| GO:BP | GO:0046122 | purine deoxyribonucleoside metabolic process | 1 | DGUOK | 3 | 0.2644199 |
| GO:BP | GO:0016032 | viral process | 13 | HDAC1,VPS37C,RAN,LIG4,CHMP1A,HEXIM1,CHMP6,RAB1A,SMARCB1,SPCS1,TMEM39A,RAB7A,CTBP1 | 347 | 0.2661737 |
| GO:BP | GO:1903650 | negative regulation of cytoplasmic transport | 1 | SNX12 | 3 | 0.2661737 |
| GO:BP | GO:0006693 | prostaglandin metabolic process | 2 | GSTP1,CES2 | 32 | 0.2662427 |
| GO:BP | GO:0090239 | regulation of histone H4 acetylation | 1 | CTBP1 | 4 | 0.2668909 |
| GO:BP | GO:0002091 | negative regulation of receptor internalization | 1 | ANKRD13D | 14 | 0.2668909 |
| GO:BP | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum | 1 | UBAC2 | 10 | 0.2678235 |
| GO:BP | GO:0060056 | mammary gland involution | 1 | PML | 8 | 0.2678235 |
| GO:BP | GO:0046469 | platelet activating factor metabolic process | 1 | PAFAH1B1 | 5 | 0.2678235 |
| GO:BP | GO:0046488 | phosphatidylinositol metabolic process | 2 | PIGC,IPMK | 135 | 0.2678235 |
| GO:BP | GO:0051098 | regulation of binding | 1 | PEX14 | 314 | 0.2678235 |
| GO:BP | GO:0006903 | vesicle targeting | 1 | TRAPPC3 | 62 | 0.2678235 |
| GO:BP | GO:1902036 | regulation of hematopoietic stem cell differentiation | 1 | KAT5 | 15 | 0.2678235 |
| GO:BP | GO:0051904 | pigment granule transport | 2 | RAB1A,BBS7 | 19 | 0.2678235 |
| GO:BP | GO:0086004 | regulation of cardiac muscle cell contraction | 1 | ADORA1 | 34 | 0.2678235 |
| GO:BP | GO:0032535 | regulation of cellular component size | 7 | BLOC1S2,BDNF,PPP1CA,AQP11,E2F4,SLC12A4,PAFAH1B1 | 306 | 0.2678235 |
| GO:BP | GO:0032401 | establishment of melanosome localization | 2 | RAB1A,BBS7 | 20 | 0.2678235 |
| GO:BP | GO:0051254 | positive regulation of RNA metabolic process | 24 | PITHD1,HDAC1,MED8,LMO4,VPS72,ECD,PPP3CB,ANKRD1,BLOC1S2,POLR2G,KAT5,RBM14,MED17,ANKRD49,TBK1,TRIAP1,GTF2F2,ING1,BRF1,TRIP4,PML,ARL2BP,E2F4,ZFP90 | 1422 | 0.2678235 |
| GO:BP | GO:0051649 | establishment of localization in cell | 2 | ICMT,PEX14 | 1841 | 0.2678235 |
| GO:BP | GO:0010332 | response to gamma radiation | 2 | LIG4,PML | 47 | 0.2678235 |
| GO:BP | GO:0010824 | regulation of centrosome duplication | 2 | RBM14,CHMP1A | 44 | 0.2684078 |
| GO:BP | GO:0033674 | positive regulation of kinase activity | 3 | LMO4,DUSP12,ADORA1 | 307 | 0.2684078 |
| GO:BP | GO:0050790 | regulation of catalytic activity | 8 | ASAP3,HDAC1,LMO4,DUSP12,TIPRL,ADORA1,AIDA,PSEN2 | 1348 | 0.2684078 |
| GO:BP | GO:0035878 | nail development | 1 | PRKAB1 | 8 | 0.2684078 |
| GO:BP | GO:0071560 | cellular response to transforming growth factor beta stimulus | 5 | HDAC1,ANKRD1,BRMS1,ING1,PML | 222 | 0.2684078 |
| GO:BP | GO:0051293 | establishment of spindle localization | 3 | KAT5,PAFAH1B1,NSFL1C | 49 | 0.2684078 |
| GO:BP | GO:0043632 | modification-dependent macromolecule catabolic process | 24 | RNF19B,HERC4,TRIM3,VPS37C,KAT5,TRIP4,PML,CHMP1A,PEX12,SPOP,CHMP6,FZR1,STAM2,PSMD14,NSFL1C,ASCC2,MKRN2,BBS7,UFL1,FBXL4,PSMB1,RNF216,TMEM168,PHF20L1 | 638 | 0.2684078 |
| GO:BP | GO:0042439 | ethanolamine-containing compound metabolic process | 1 | GDPD1 | 5 | 0.2684078 |
| GO:BP | GO:0043038 | amino acid activation | 3 | FARSA,HARS2,RARS1 | 44 | 0.2684078 |
| GO:BP | GO:0030111 | regulation of Wnt signaling pathway | 7 | HDAC1,PPP1CA,UBAC2,GSKIP,NXN,NLE1,MKS1 | 273 | 0.2684078 |
| GO:BP | GO:0006692 | prostanoid metabolic process | 2 | GSTP1,CES2 | 33 | 0.2693658 |
| GO:BP | GO:0017157 | regulation of exocytosis | 1 | CPLANE2 | 139 | 0.2699896 |
| GO:BP | GO:0006475 | internal protein amino acid acetylation | 6 | VPS72,KAT5,PHF20,ACTL6A,CTBP1,PHF20L1 | 116 | 0.2702152 |
| GO:BP | GO:0036498 | IRE1-mediated unfolded protein response | 2 | BAK1,UFL1 | 19 | 0.2711026 |
| GO:BP | GO:0043067 | regulation of programmed cell death | 12 | HDAC1,VPS72,LMNA,ADORA1,PSEN2,ANKRD1,BDNF,KAT5,BRMS1,RAD9A,PPP1CA,GSTP1 | 1125 | 0.2711269 |
| GO:BP | GO:0051130 | positive regulation of cellular component organization | 1 | WRAP73 | 906 | 0.2711269 |
| GO:BP | GO:0031056 | regulation of histone modification | 4 | PML,PHF20,CTBP1,NELFA | 76 | 0.2711415 |
| GO:BP | GO:0006369 | termination of RNA polymerase II transcription | 1 | PCF11 | 9 | 0.2711415 |
| GO:BP | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway | 2 | PPP1CA,PML | 41 | 0.2714996 |
| GO:BP | GO:0031929 | TOR signaling | 4 | TIPRL,WDR24,RPS6KB1,RPTOR | 119 | 0.2716446 |
| GO:BP | GO:0048661 | positive regulation of smooth muscle cell proliferation | 1 | HDAC1 | 60 | 0.2719058 |
| GO:BP | GO:0006259 | DNA metabolic process | 15 | DCLRE1B,VPS72,LMNA,SDE2,ANKRD1,DCLRE1A,KAT5,RAD9A,EMSY,KMT5A,RAN,LIG4,PML,ERCC4,TERF2IP | 888 | 0.2719686 |
| GO:BP | GO:0071453 | cellular response to oxygen levels | 2 | LMNA,SUV39H2 | 144 | 0.2719993 |
| GO:BP | GO:1900180 | regulation of protein localization to nucleus | 2 | LMNA,PPP3CB | 124 | 0.2721414 |
| GO:BP | GO:1903421 | regulation of synaptic vesicle recycling | 1 | PPP3CB | 23 | 0.2721414 |
| GO:BP | GO:1901700 | response to oxygen-containing compound | 2 | PEX14,AGTRAP | 1220 | 0.2721414 |
| GO:BP | GO:0031342 | negative regulation of cell killing | 1 | PPP3CB | 11 | 0.2721414 |
| GO:BP | GO:0001826 | inner cell mass cell differentiation | 1 | NLE1 | 5 | 0.2721414 |
| GO:BP | GO:1902570 | protein localization to nucleolus | 2 | RAN,NOL8 | 16 | 0.2722262 |
| GO:BP | GO:0035994 | response to muscle stretch | 1 | ANKRD1 | 25 | 0.2724518 |
| GO:BP | GO:0021510 | spinal cord development | 2 | LMO4,SCYL1 | 61 | 0.2729653 |
| GO:BP | GO:0030522 | intracellular receptor signaling pathway | 6 | HDAC1,TRIM3,TBK1,CRY1,TRIP4,PML | 254 | 0.2729653 |
| GO:BP | GO:0034612 | response to tumor necrosis factor | 7 | ANKRD1,GSTP1,TBK1,RPS6KB1,PIAS4,MAP2K7,MAP4K3 | 176 | 0.2730660 |
| GO:BP | GO:0032228 | regulation of synaptic transmission, GABAergic | 1 | ADORA1 | 23 | 0.2732057 |
| GO:BP | GO:0000491 | small nucleolar ribonucleoprotein complex assembly | 1 | NOPCHAP1 | 12 | 0.2732057 |
| GO:BP | GO:0007492 | endoderm development | 1 | HDAC1 | 65 | 0.2732057 |
| GO:BP | GO:0043392 | negative regulation of DNA binding | 2 | ERCC4,ZFP90 | 44 | 0.2732057 |
| GO:BP | GO:0035092 | sperm DNA condensation | 1 | KAT5 | 7 | 0.2732057 |
| GO:BP | GO:1901678 | iron coordination entity transport | 1 | SLC48A1 | 11 | 0.2732057 |
| GO:BP | GO:0042753 | positive regulation of circadian rhythm | 1 | KAT5 | 9 | 0.2732057 |
| GO:BP | GO:0140861 | DNA repair-dependent chromatin remodeling | 1 | KAT5 | 18 | 0.2732057 |
| GO:BP | GO:0001845 | phagolysosome assembly | 2 | RAB7A,RAB14 | 14 | 0.2732057 |
| GO:BP | GO:0006979 | response to oxidative stress | 1 | PEX14 | 327 | 0.2733391 |
| GO:BP | GO:0061370 | testosterone biosynthetic process | 1 | HSD17B1 | 4 | 0.2737212 |
| GO:BP | GO:1901983 | regulation of protein acetylation | 2 | KAT5,PML | 49 | 0.2739196 |
| GO:BP | GO:0014888 | striated muscle adaptation | 3 | LMNA,RPS6KB1,GTF2IRD1 | 39 | 0.2739196 |
| GO:BP | GO:0035933 | glucocorticoid secretion | 1 | CRY1 | 7 | 0.2741203 |
| GO:BP | GO:0021894 | cerebral cortex GABAergic interneuron development | 1 | RAC3 | 3 | 0.2741203 |
| GO:BP | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore | 2 | KAT5,MAD1L1 | 21 | 0.2746888 |
| GO:BP | GO:0051905 | establishment of pigment granule localization | 2 | RAB1A,BBS7 | 20 | 0.2746977 |
| GO:BP | GO:0030518 | intracellular steroid hormone receptor signaling pathway | 3 | HDAC1,CRY1,TRIP4 | 95 | 0.2746977 |
| GO:BP | GO:1902751 | positive regulation of cell cycle G2/M phase transition | 2 | CDK4,MTA3 | 31 | 0.2746977 |
| GO:BP | GO:0005980 | glycogen catabolic process | 1 | PPP1CA | 15 | 0.2746977 |
| GO:BP | GO:0071375 | cellular response to peptide hormone stimulus | 1 | AGTRAP | 235 | 0.2746977 |
| GO:BP | GO:0039533 | regulation of MDA-5 signaling pathway | 1 | RIOK3 | 5 | 0.2746977 |
| GO:BP | GO:0030336 | negative regulation of cell migration | 5 | HDAC1,ADORA1,BRMS1,NAV3,ING1 | 224 | 0.2751016 |
| GO:BP | GO:1904688 | regulation of cytoplasmic translational initiation | 1 | IMPACT | 7 | 0.2751016 |
| GO:BP | GO:0036066 | protein O-linked fucosylation | 1 | SLC35C2 | 5 | 0.2760008 |
| GO:BP | GO:0055086 | nucleobase-containing small molecule metabolic process | 1 | ICMT | 486 | 0.2760008 |
| GO:BP | GO:1902905 | positive regulation of supramolecular fiber organization | 1 | ARHGEF10L | 149 | 0.2760008 |
| GO:BP | GO:0071559 | response to transforming growth factor beta | 5 | HDAC1,ANKRD1,BRMS1,ING1,PML | 227 | 0.2763180 |
| GO:BP | GO:1901385 | regulation of voltage-gated calcium channel activity | 3 | PPP3CB,SRI,PPP3CC | 29 | 0.2763180 |
| GO:BP | GO:0032958 | inositol phosphate biosynthetic process | 1 | IPMK | 20 | 0.2765200 |
| GO:BP | GO:0006950 | response to stress | 27 | PEX14,AGTRAP,PLEKHM2,ARHGEF10L,RNF19B,DCLRE1B,VPS72,LMNA,TIPRL,ADORA1,AIDA,SDE2,PSEN2,SUV39H2,ANKRD1,DCLRE1A,TRIM3,STK33,SPINDOC,SCYL1,KAT5,RBM14,RAD9A,PPP1CA,GSTP1,EMSY,AQP11 | 2767 | 0.2765200 |
| GO:BP | GO:0051851 | modulation by host of symbiont process | 1 | HDAC1 | 71 | 0.2770106 |
| GO:BP | GO:0048597 | post-embryonic camera-type eye morphogenesis | 1 | BAK1 | 4 | 0.2770307 |
| GO:BP | GO:1900120 | regulation of receptor binding | 1 | BDNF | 17 | 0.2772189 |
| GO:BP | GO:0022607 | cellular component assembly | 5 | WRAP73,PEX14,CPLANE2,ARHGEF10L,ASAP3 | 2472 | 0.2772189 |
| GO:BP | GO:0070346 | positive regulation of fat cell proliferation | 1 | PPARD | 3 | 0.2772189 |
| GO:BP | GO:0046847 | filopodium assembly | 2 | ARAP1,RAB3IP | 56 | 0.2772189 |
| GO:BP | GO:0045995 | regulation of embryonic development | 5 | CCSAP,PAFAH1B1,INO80D,ACTL6A,RAB14 | 80 | 0.2779664 |
| GO:BP | GO:1902172 | regulation of keratinocyte apoptotic process | 1 | PIAS4 | 5 | 0.2785388 |
| GO:BP | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | 1 | KAT5 | 18 | 0.2785388 |
| GO:BP | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore | 1 | KAT5 | 18 | 0.2785388 |
| GO:BP | GO:0050890 | cognition | 7 | ADORA1,PPP3CB,BDNF,TTC8,PAFAH1B1,RPS6KB1,EIF4A3 | 225 | 0.2785388 |
| GO:BP | GO:0097283 | keratinocyte apoptotic process | 1 | PIAS4 | 5 | 0.2785388 |
| GO:BP | GO:0070328 | triglyceride homeostasis | 1 | ADORA1 | 18 | 0.2785388 |
| GO:BP | GO:0055090 | acylglycerol homeostasis | 1 | ADORA1 | 18 | 0.2785388 |
| GO:BP | GO:0006893 | Golgi to plasma membrane transport | 3 | RAB3IP,RABEP1,ARFGEF2 | 58 | 0.2787301 |
| GO:BP | GO:0072318 | clathrin coat disassembly | 1 | SH3GL1 | 7 | 0.2787895 |
| GO:BP | GO:0051865 | protein autoubiquitination | 1 | RNF19B | 76 | 0.2787895 |
| GO:BP | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic | 1 | POLR2G | 18 | 0.2787895 |
| GO:BP | GO:0002710 | negative regulation of T cell mediated immunity | 1 | PPP3CB | 9 | 0.2787895 |
| GO:BP | GO:0042149 | cellular response to glucose starvation | 3 | KAT5,PICK1,CPEB4 | 46 | 0.2792215 |
| GO:BP | GO:0050714 | positive regulation of protein secretion | 2 | PPP3CB,ANKRD1 | 103 | 0.2792215 |
| GO:BP | GO:0051047 | positive regulation of secretion | 3 | ADORA1,PPP3CB,ANKRD1 | 209 | 0.2792215 |
| GO:BP | GO:0051171 | regulation of nitrogen compound metabolic process | 95 | PEX14,PITHD1,HDAC1,RNF19B,MED8,LMO4,VPS72,LMNA,TIPRL,ADORA1,AIDA,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,BUB3,ZNF195,TRIM3,BDNF,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,GSTP1,EMSY,AQP11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,DIABLO,KMT5A,ZNF605,GTF2F2,ING1,GSKIP,BRF1,BAHD1,TRIP4,PML,WDR24,ERCC4,ARL2BP,E2F4,ZFP90,TERF2IP,NXN,INCA1,ZNF287,NLE1,PEX12,CASC3,HEXIM1,OSBPL7,SPOP,SRSF1,RPS6KB1,INTS2,EIF4A3,RPTOR,CHMP6,IMPACT,MIER2,MOB3A,FZR1,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,RAB1A,ZNF638 | 4247 | 0.2799521 |
| GO:BP | GO:0043549 | regulation of kinase activity | 4 | LMO4,DUSP12,ADORA1,AIDA | 548 | 0.2799521 |
| GO:BP | GO:2000172 | regulation of branching morphogenesis of a nerve | 1 | BCL11A | 4 | 0.2804119 |
| GO:BP | GO:0009251 | glucan catabolic process | 1 | PPP1CA | 15 | 0.2804119 |
| GO:BP | GO:0016567 | protein ubiquitination | 6 | RNF19B,MED8,SDE2,HERC4,BUB3,TRIM3 | 683 | 0.2804119 |
| GO:BP | GO:0035970 | peptidyl-threonine dephosphorylation | 1 | PPP1CA | 17 | 0.2804119 |
| GO:BP | GO:0120036 | plasma membrane bounded cell projection organization | 3 | WRAP73,CPLANE2,LYPLA2 | 1202 | 0.2805102 |
| GO:BP | GO:0007018 | microtubule-based movement | 1 | PEX14 | 300 | 0.2806661 |
| GO:BP | GO:0051495 | positive regulation of cytoskeleton organization | 1 | ARHGEF10L | 156 | 0.2813192 |
| GO:BP | GO:0010463 | mesenchymal cell proliferation | 1 | LMNA | 36 | 0.2814394 |
| GO:BP | GO:0045472 | response to ether | 1 | CDK4 | 9 | 0.2815159 |
| GO:BP | GO:0006638 | neutral lipid metabolic process | 1 | LYPLA2 | 92 | 0.2816443 |
| GO:BP | GO:0014891 | striated muscle atrophy | 1 | RPS6KB1 | 6 | 0.2816443 |
| GO:BP | GO:0048631 | regulation of skeletal muscle tissue growth | 1 | RPS6KB1 | 7 | 0.2816443 |
| GO:BP | GO:0001843 | neural tube closure | 3 | LMO4,CLUAP1,MKS1 | 89 | 0.2816443 |
| GO:BP | GO:0006639 | acylglycerol metabolic process | 1 | LYPLA2 | 91 | 0.2816443 |
| GO:BP | GO:0050691 | regulation of defense response to virus by host | 3 | PML,TRAF3IP2,RNF216 | 31 | 0.2816443 |
| GO:BP | GO:1901165 | positive regulation of trophoblast cell migration | 1 | SYDE1 | 6 | 0.2816443 |
| GO:BP | GO:0032928 | regulation of superoxide anion generation | 1 | GSTP1 | 8 | 0.2816443 |
| GO:BP | GO:0008284 | positive regulation of cell population proliferation | 1 | WRAP73 | 885 | 0.2816443 |
| GO:BP | GO:0032400 | melanosome localization | 2 | RAB1A,BBS7 | 22 | 0.2816443 |
| GO:BP | GO:0042921 | glucocorticoid receptor signaling pathway | 1 | CRY1 | 12 | 0.2816443 |
| GO:BP | GO:0071389 | cellular response to mineralocorticoid stimulus | 1 | RAN | 8 | 0.2816443 |
| GO:BP | GO:0030301 | cholesterol transport | 1 | STX12 | 81 | 0.2828291 |
| GO:BP | GO:0032941 | secretion by tissue | 1 | ADORA1 | 23 | 0.2829059 |
| GO:BP | GO:0042772 | DNA damage response, signal transduction resulting in transcription | 1 | KAT5 | 19 | 0.2829059 |
| GO:BP | GO:0046854 | phosphatidylinositol phosphate biosynthetic process | 3 | IPMK,TMEM150A,INPP1 | 57 | 0.2829059 |
| GO:BP | GO:0003016 | respiratory system process | 1 | ADORA1 | 29 | 0.2829059 |
| GO:BP | GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 2 | LMNA,GSTP1 | 78 | 0.2829059 |
| GO:BP | GO:0042475 | odontogenesis of dentin-containing tooth | 1 | HDAC1 | 55 | 0.2829059 |
| GO:BP | GO:0098792 | xenophagy | 1 | TBK1 | 12 | 0.2829059 |
| GO:BP | GO:1903115 | regulation of actin filament-based movement | 1 | ADORA1 | 39 | 0.2829059 |
| GO:BP | GO:0010866 | regulation of triglyceride biosynthetic process | 1 | KAT5 | 19 | 0.2829059 |
| GO:BP | GO:0060606 | tube closure | 3 | LMO4,CLUAP1,MKS1 | 90 | 0.2831292 |
| GO:BP | GO:0032886 | regulation of microtubule-based process | 6 | CCSAP,RBM14,NAV3,CHMP1A,PAFAH1B1,CHMP6 | 216 | 0.2831292 |
| GO:BP | GO:0140239 | postsynaptic endocytosis | 1 | AP2A2 | 19 | 0.2831292 |
| GO:BP | GO:0098884 | postsynaptic neurotransmitter receptor internalization | 1 | AP2A2 | 19 | 0.2831292 |
| GO:BP | GO:0006405 | RNA export from nucleus | 3 | RAN,CASC3,EIF4A3 | 79 | 0.2831292 |
| GO:BP | GO:0043243 | positive regulation of protein-containing complex disassembly | 1 | JMJD4 | 30 | 0.2836384 |
| GO:BP | GO:0046888 | negative regulation of hormone secretion | 2 | ADORA1,CRY1 | 49 | 0.2836384 |
| GO:BP | GO:0045017 | glycerolipid biosynthetic process | 8 | PIGC,IPMK,KAT5,PGS1,TMEM150A,INPP1,TAMM41,SACM1L | 215 | 0.2838769 |
| GO:BP | GO:0031062 | positive regulation of histone methylation | 2 | PHF20,NELFA | 23 | 0.2842737 |
| GO:BP | GO:1901097 | negative regulation of autophagosome maturation | 1 | TMEM39A | 5 | 0.2844729 |
| GO:BP | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus | 1 | EIF4A3 | 8 | 0.2845844 |
| GO:BP | GO:0051090 | regulation of DNA-binding transcription factor activity | 1 | PEX14 | 332 | 0.2845844 |
| GO:BP | GO:0001942 | hair follicle development | 1 | HDAC1 | 68 | 0.2845844 |
| GO:BP | GO:0000729 | DNA double-strand break processing | 2 | SMARCAD1,UBE2V2 | 19 | 0.2845844 |
| GO:BP | GO:0001945 | lymph vessel development | 1 | PPP3CB | 22 | 0.2845844 |
| GO:BP | GO:0006892 | post-Golgi vesicle-mediated transport | 3 | MON2,RAB3IP,RABEP1 | 101 | 0.2845844 |
| GO:BP | GO:0022615 | protein to membrane docking | 1 | RAB7A | 5 | 0.2845844 |
| GO:BP | GO:1902415 | regulation of mRNA binding | 1 | EIF4A3 | 8 | 0.2845844 |
| GO:BP | GO:1904978 | regulation of endosome organization | 1 | RAB7A | 5 | 0.2845844 |
| GO:BP | GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 5 | CDK4,FZR1,MTA3,HUS1,RINT1 | 94 | 0.2851465 |
| GO:BP | GO:0002328 | pro-B cell differentiation | 1 | LIG4 | 10 | 0.2858232 |
| GO:BP | GO:0099518 | vesicle cytoskeletal trafficking | 3 | BLOC1S2,PAFAH1B1,RAB1A | 61 | 0.2859238 |
| GO:BP | GO:0061061 | muscle structure development | 6 | LMNA,PPP3CB,SYNPO2L,ANKRD1,BDNF,KAT5 | 551 | 0.2859238 |
| GO:BP | GO:0051642 | centrosome localization | 2 | PAFAH1B1,RANBP2 | 31 | 0.2860731 |
| GO:BP | GO:0030030 | cell projection organization | 3 | WRAP73,CPLANE2,LYPLA2 | 1235 | 0.2860731 |
| GO:BP | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 2 | CHMP6,RAB7A | 26 | 0.2860731 |
| GO:BP | GO:0061842 | microtubule organizing center localization | 2 | PAFAH1B1,RANBP2 | 31 | 0.2860731 |
| GO:BP | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 1 | RNF19B | 86 | 0.2860731 |
| GO:BP | GO:0032728 | positive regulation of interferon-beta production | 2 | TBK1,RIOK3 | 30 | 0.2861908 |
| GO:BP | GO:0061469 | regulation of type B pancreatic cell proliferation | 1 | CDK4 | 12 | 0.2861908 |
| GO:BP | GO:0090208 | positive regulation of triglyceride metabolic process | 1 | KAT5 | 16 | 0.2861908 |
| GO:BP | GO:0032811 | negative regulation of epinephrine secretion | 1 | ADRA2C | 2 | 0.2861908 |
| GO:BP | GO:0009124 | nucleoside monophosphate biosynthetic process | 3 | DGUOK,PAICS,UPRT | 37 | 0.2861908 |
| GO:BP | GO:0042791 | 5S class rRNA transcription by RNA polymerase III | 1 | GTF3C3 | 6 | 0.2861908 |
| GO:BP | GO:0072665 | protein localization to vacuole | 4 | VPS37C,STAM2,RAB7A,ZFYVE16 | 73 | 0.2861908 |
| GO:BP | GO:0035305 | negative regulation of dephosphorylation | 1 | TIPRL | 38 | 0.2861908 |
| GO:BP | GO:0032056 | positive regulation of translation in response to stress | 1 | IMPACT | 8 | 0.2861908 |
| GO:BP | GO:0032438 | melanosome organization | 2 | BLOC1S2,AP1M1 | 36 | 0.2861908 |
| GO:BP | GO:0035624 | receptor transactivation | 1 | ADRA2C | 3 | 0.2861908 |
| GO:BP | GO:0010700 | negative regulation of norepinephrine secretion | 1 | ADRA2C | 2 | 0.2861908 |
| GO:BP | GO:1904903 | ESCRT III complex disassembly | 1 | CHMP1A | 10 | 0.2861908 |
| GO:BP | GO:0051653 | spindle localization | 3 | KAT5,PAFAH1B1,NSFL1C | 53 | 0.2861908 |
| GO:BP | GO:0022405 | hair cycle process | 1 | HDAC1 | 70 | 0.2861908 |
| GO:BP | GO:0022404 | molting cycle process | 1 | HDAC1 | 70 | 0.2861908 |
| GO:BP | GO:1904896 | ESCRT complex disassembly | 1 | CHMP1A | 10 | 0.2861908 |
| GO:BP | GO:0048512 | circadian behavior | 1 | ADORA1 | 30 | 0.2861908 |
| GO:BP | GO:0048488 | synaptic vesicle endocytosis | 4 | PPP3CB,SH3GL1,CTBP1,PPP3CC | 62 | 0.2861908 |
| GO:BP | GO:0030163 | protein catabolic process | 3 | PITHD1,LYPLA2,RNF19B | 906 | 0.2861908 |
| GO:BP | GO:0015937 | coenzyme A biosynthetic process | 1 | PPCDC | 11 | 0.2861908 |
| GO:BP | GO:0051875 | pigment granule localization | 2 | RAB1A,BBS7 | 22 | 0.2867467 |
| GO:BP | GO:0045445 | myoblast differentiation | 5 | KAT5,TRIP4,SMARCB1,ACTL6A,PPARD | 90 | 0.2867467 |
| GO:BP | GO:0051660 | establishment of centrosome localization | 1 | PAFAH1B1 | 8 | 0.2867467 |
| GO:BP | GO:0007613 | memory | 2 | PPP3CB,BDNF | 93 | 0.2867467 |
| GO:BP | GO:0032446 | protein modification by small protein conjugation | 28 | RNF19B,MED8,SDE2,HERC4,BUB3,TRIM3,MED17,CRY1,PML,NXN,PEX12,SPOP,FZR1,PIAS4,EIPR1,BCL11A,RANBP2,DCAF17,MKRN2,MED7,ZNF451,UFL1,TRAF3IP2,RNF216,DTX2,TRIM35,UBE2V2,KLHL9 | 758 | 0.2867467 |
| GO:BP | GO:1901874 | negative regulation of post-translational protein modification | 3 | BUB3,CRY1,NXN | 98 | 0.2867467 |
| GO:BP | GO:0031958 | corticosteroid receptor signaling pathway | 1 | CRY1 | 13 | 0.2867467 |
| GO:BP | GO:0051081 | nuclear membrane disassembly | 1 | PAFAH1B1 | 10 | 0.2867467 |
| GO:BP | GO:0033504 | floor plate development | 1 | CLUAP1 | 8 | 0.2879751 |
| GO:BP | GO:0009650 | UV protection | 1 | ERCC4 | 11 | 0.2890719 |
| GO:BP | GO:0051955 | regulation of amino acid transport | 1 | ADORA1 | 28 | 0.2890719 |
| GO:BP | GO:0000272 | polysaccharide catabolic process | 1 | PPP1CA | 15 | 0.2890719 |
| GO:BP | GO:0071383 | cellular response to steroid hormone stimulus | 5 | HDAC1,CRY1,RAN,TRIP4,RPS6KB1 | 165 | 0.2890719 |
| GO:BP | GO:0090257 | regulation of muscle system process | 2 | LMNA,ADORA1 | 180 | 0.2890719 |
| GO:BP | GO:0010256 | endomembrane system organization | 15 | PLEKHM2,LMNA,COG2,BLOC1S2,VPS37C,AQP11,COG7,CHMP1A,PAFAH1B1,CHMP6,AP1M1,RAB1A,STAM2,NSFL1C,ARFGEF2 | 497 | 0.2890719 |
| GO:BP | GO:0001738 | morphogenesis of a polarized epithelium | 3 | TTC8,PAFAH1B1,MKS1 | 88 | 0.2896343 |
| GO:BP | GO:0014013 | regulation of gliogenesis | 1 | HDAC1 | 66 | 0.2896343 |
| GO:BP | GO:0010611 | regulation of cardiac muscle hypertrophy | 1 | LMNA | 46 | 0.2896343 |
| GO:BP | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation | 2 | ARFIP2,PICK1 | 25 | 0.2898082 |
| GO:BP | GO:2001258 | negative regulation of cation channel activity | 3 | PPP3CB,SRI,PPP3CC | 31 | 0.2898924 |
| GO:BP | GO:1901653 | cellular response to peptide | 1 | AGTRAP | 278 | 0.2898924 |
| GO:BP | GO:0048753 | pigment granule organization | 2 | BLOC1S2,AP1M1 | 37 | 0.2898924 |
| GO:BP | GO:0140238 | presynaptic endocytosis | 4 | PPP3CB,SH3GL1,CTBP1,PPP3CC | 63 | 0.2898924 |
| GO:BP | GO:0019080 | viral gene expression | 1 | HDAC1 | 97 | 0.2898924 |
| GO:BP | GO:0003266 | regulation of secondary heart field cardioblast proliferation | 1 | MKS1 | 8 | 0.2898924 |
| GO:BP | GO:0046474 | glycerophospholipid biosynthetic process | 7 | PIGC,IPMK,PGS1,TMEM150A,INPP1,TAMM41,SACM1L | 186 | 0.2898924 |
| GO:BP | GO:0035307 | positive regulation of protein dephosphorylation | 1 | ADORA1 | 35 | 0.2898924 |
| GO:BP | GO:0072319 | vesicle uncoating | 1 | SH3GL1 | 8 | 0.2898924 |
| GO:BP | GO:0071605 | monocyte chemotactic protein-1 production | 1 | GSTP1 | 7 | 0.2898924 |
| GO:BP | GO:0051769 | regulation of nitric-oxide synthase biosynthetic process | 1 | GSTP1 | 13 | 0.2898924 |
| GO:BP | GO:0046605 | regulation of centrosome cycle | 2 | RBM14,CHMP1A | 51 | 0.2898924 |
| GO:BP | GO:1900271 | regulation of long-term synaptic potentiation | 1 | ADORA1 | 33 | 0.2898924 |
| GO:BP | GO:0007622 | rhythmic behavior | 1 | ADORA1 | 32 | 0.2898924 |
| GO:BP | GO:0051767 | nitric-oxide synthase biosynthetic process | 1 | GSTP1 | 13 | 0.2898924 |
| GO:BP | GO:1905279 | regulation of retrograde transport, endosome to Golgi | 1 | EIPR1 | 6 | 0.2898924 |
| GO:BP | GO:0071637 | regulation of monocyte chemotactic protein-1 production | 1 | GSTP1 | 7 | 0.2898924 |
| GO:BP | GO:0002260 | lymphocyte homeostasis | 4 | PPP3CB,SLC39A3,BAK1,TRAF3IP2 | 49 | 0.2903365 |
| GO:BP | GO:1904152 | regulation of retrograde protein transport, ER to cytosol | 1 | UBAC2 | 13 | 0.2903365 |
| GO:BP | GO:2001140 | positive regulation of phospholipid transport | 1 | TRIAP1 | 11 | 0.2903365 |
| GO:BP | GO:0032506 | cytokinetic process | 2 | CHMP1A,CHMP6 | 42 | 0.2903365 |
| GO:BP | GO:0043501 | skeletal muscle adaptation | 2 | RPS6KB1,GTF2IRD1 | 19 | 0.2903365 |
| GO:BP | GO:2000146 | negative regulation of cell motility | 5 | HDAC1,ADORA1,BRMS1,NAV3,ING1 | 233 | 0.2907018 |
| GO:BP | GO:0014902 | myotube differentiation | 2 | PPP3CB,BDNF | 88 | 0.2907018 |
| GO:BP | GO:0018022 | peptidyl-lysine methylation | 4 | SUV39H2,KMT5A,PHF20,NELFA | 83 | 0.2910474 |
| GO:BP | GO:0071285 | cellular response to lithium ion | 1 | LIG4 | 8 | 0.2915284 |
| GO:BP | GO:0048709 | oligodendrocyte differentiation | 1 | HDAC1 | 72 | 0.2915284 |
| GO:BP | GO:0015918 | sterol transport | 1 | STX12 | 93 | 0.2925974 |
| GO:BP | GO:0034472 | snRNA 3’-end processing | 2 | INTS2,INTS8 | 21 | 0.2930758 |
| GO:BP | GO:0016556 | mRNA modification | 2 | TRMT61B,METTL8 | 32 | 0.2932382 |
| GO:BP | GO:0032459 | regulation of protein oligomerization | 1 | BCL11A | 7 | 0.2932382 |
| GO:BP | GO:0051494 | negative regulation of cytoskeleton organization | 3 | RBM14,ARAP1,NAV3 | 136 | 0.2932382 |
| GO:BP | GO:0061098 | positive regulation of protein tyrosine kinase activity | 1 | ADORA1 | 33 | 0.2932382 |
| GO:BP | GO:0051974 | negative regulation of telomerase activity | 1 | PML | 11 | 0.2932382 |
| GO:BP | GO:0010288 | response to lead ion | 1 | PPP1CA | 17 | 0.2932382 |
| GO:BP | GO:2000819 | regulation of nucleotide-excision repair | 2 | SMARCB1,ACTL6A | 27 | 0.2932382 |
| GO:BP | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity | 1 | SPATC1L | 5 | 0.2940755 |
| GO:BP | GO:0014020 | primary neural tube formation | 3 | LMO4,CLUAP1,MKS1 | 93 | 0.2944906 |
| GO:BP | GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway | 3 | HDAC1,BRMS1,ING1 | 126 | 0.2949792 |
| GO:BP | GO:0035627 | ceramide transport | 1 | GLTP | 14 | 0.2951927 |
| GO:BP | GO:0042311 | vasodilation | 1 | ADORA1 | 37 | 0.2951927 |
| GO:BP | GO:0035025 | positive regulation of Rho protein signal transduction | 1 | SYNPO2L | 21 | 0.2951927 |
| GO:BP | GO:0045879 | negative regulation of smoothened signaling pathway | 1 | HERC4 | 30 | 0.2951927 |
| GO:BP | GO:0043268 | positive regulation of potassium ion transport | 1 | ADORA1 | 31 | 0.2951927 |
| GO:BP | GO:0050657 | nucleic acid transport | 5 | RAN,CASC3,SRSF1,EIF4A3,RANBP2 | 141 | 0.2951927 |
| GO:BP | GO:0009215 | purine deoxyribonucleoside triphosphate metabolic process | 1 | DGUOK | 7 | 0.2951927 |
| GO:BP | GO:0043651 | linoleic acid metabolic process | 1 | GSTP1 | 12 | 0.2951927 |
| GO:BP | GO:0050658 | RNA transport | 5 | RAN,CASC3,SRSF1,EIF4A3,RANBP2 | 141 | 0.2951927 |
| GO:BP | GO:0046053 | dAMP metabolic process | 1 | DGUOK | 5 | 0.2951927 |
| GO:BP | GO:0014743 | regulation of muscle hypertrophy | 1 | LMNA | 47 | 0.2951927 |
| GO:BP | GO:0031063 | regulation of histone deacetylation | 2 | PML,CTBP1 | 26 | 0.2951927 |
| GO:BP | GO:1902031 | regulation of NADP metabolic process | 1 | RPTOR | 8 | 0.2956884 |
| GO:BP | GO:0006473 | protein acetylation | 6 | VPS72,KAT5,PML,PHF20,ACTL6A,CTBP1 | 154 | 0.2956884 |
| GO:BP | GO:0007338 | single fertilization | 1 | PITHD1 | 69 | 0.2956884 |
| GO:BP | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 1 | HDAC1 | 98 | 0.2956884 |
| GO:BP | GO:1903320 | regulation of protein modification by small protein conjugation or removal | 6 | BUB3,CRY1,NXN,PEX12,FZR1,PIAS4 | 231 | 0.2956884 |
| GO:BP | GO:0046486 | glycerolipid metabolic process | 3 | LYPLA2,PIGC,IPMK | 302 | 0.2958264 |
| GO:BP | GO:1903322 | positive regulation of protein modification by small protein conjugation or removal | 4 | CRY1,PEX12,FZR1,PIAS4 | 125 | 0.2961257 |
| GO:BP | GO:0030397 | membrane disassembly | 1 | PAFAH1B1 | 11 | 0.2973018 |
| GO:BP | GO:0007179 | transforming growth factor beta receptor signaling pathway | 4 | HDAC1,BRMS1,ING1,PML | 177 | 0.2973018 |
| GO:BP | GO:1902262 | apoptotic process involved in blood vessel morphogenesis | 1 | BAK1 | 4 | 0.2973018 |
| GO:BP | GO:1990090 | cellular response to nerve growth factor stimulus | 2 | BDNF,EIF4A3 | 41 | 0.2973018 |
| GO:BP | GO:0043415 | positive regulation of skeletal muscle tissue regeneration | 1 | PPARD | 3 | 0.2973018 |
| GO:BP | GO:2000275 | regulation of oxidative phosphorylation uncoupler activity | 1 | PPARD | 5 | 0.2973018 |
| GO:BP | GO:0006650 | glycerophospholipid metabolic process | 9 | PIGC,IPMK,PAFAH1B1,GDPD1,PGS1,TMEM150A,INPP1,TAMM41,SACM1L | 243 | 0.2973018 |
| GO:BP | GO:0048701 | embryonic cranial skeleton morphogenesis | 2 | EIF4A3,SLC39A3 | 31 | 0.2973760 |
| GO:BP | GO:0046328 | regulation of JNK cascade | 4 | AIDA,GSTP1,PAFAH1B1,MAP2K7 | 113 | 0.2974552 |
| GO:BP | GO:2001138 | regulation of phospholipid transport | 1 | TRIAP1 | 12 | 0.2992554 |
| GO:BP | GO:0046599 | regulation of centriole replication | 1 | RBM14 | 21 | 0.2992645 |
| GO:BP | GO:0044085 | cellular component biogenesis | 5 | WRAP73,PEX14,CPLANE2,ARHGEF10L,ASAP3 | 2735 | 0.2992645 |
| GO:BP | GO:0050688 | regulation of defense response to virus | 5 | PML,RIOK3,TRAF3IP2,RNF216,ZDHHC12 | 73 | 0.2995103 |
| GO:BP | GO:1903844 | regulation of cellular response to transforming growth factor beta stimulus | 3 | HDAC1,BRMS1,ING1 | 127 | 0.3006970 |
| GO:BP | GO:0045591 | positive regulation of regulatory T cell differentiation | 1 | KAT5 | 14 | 0.3006970 |
| GO:BP | GO:0045776 | negative regulation of blood pressure | 1 | ADORA1 | 30 | 0.3006970 |
| GO:BP | GO:0019219 | regulation of nucleobase-containing compound metabolic process | 70 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,ING1,BRF1,BAHD1,TRIP4,PML,ERCC4,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,CASC3,HEXIM1,SRSF1,INTS2,EIF4A3,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,ZNF638 | 3063 | 0.3006970 |
| GO:BP | GO:1903895 | negative regulation of IRE1-mediated unfolded protein response | 1 | UFL1 | 5 | 0.3006970 |
| GO:BP | GO:0006509 | membrane protein ectodomain proteolysis | 1 | PSEN2 | 34 | 0.3006970 |
| GO:BP | GO:1990592 | protein K69-linked ufmylation | 1 | UFL1 | 5 | 0.3006970 |
| GO:BP | GO:1990564 | protein polyufmylation | 1 | UFL1 | 5 | 0.3006970 |
| GO:BP | GO:0034205 | amyloid-beta formation | 1 | PSEN2 | 41 | 0.3006970 |
| GO:BP | GO:0003264 | regulation of cardioblast proliferation | 1 | MKS1 | 9 | 0.3021449 |
| GO:BP | GO:0003263 | cardioblast proliferation | 1 | MKS1 | 9 | 0.3021449 |
| GO:BP | GO:0070528 | protein kinase C signaling | 1 | ANKRD1 | 23 | 0.3024637 |
| GO:BP | GO:0051247 | positive regulation of protein metabolic process | 23 | RNF19B,ADORA1,JMJD4,BDNF,POLR2G,KAT5,BRMS1,TBK1,CRY1,DIABLO,PML,WDR24,ARL2BP,PEX12,OSBPL7,RPS6KB1,EIF4A3,RPTOR,IMPACT,MOB3A,FZR1,PIAS4,MAP2K7 | 1065 | 0.3026804 |
| GO:BP | GO:2000846 | regulation of corticosteroid hormone secretion | 1 | CRY1 | 9 | 0.3027448 |
| GO:BP | GO:0032989 | cellular component morphogenesis | 6 | LYPLA2,LMO4,PPP3CB,SYNPO2L,ANKRD1,BDNF | 626 | 0.3028912 |
| GO:BP | GO:0006508 | proteolysis | 4 | CPLANE2,PITHD1,HDAC1,RNF19B | 1308 | 0.3028912 |
| GO:BP | GO:1902337 | regulation of apoptotic process involved in morphogenesis | 1 | PML | 9 | 0.3028912 |
| GO:BP | GO:0051236 | establishment of RNA localization | 5 | RAN,CASC3,SRSF1,EIF4A3,RANBP2 | 144 | 0.3028912 |
| GO:BP | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region | 1 | PML | 13 | 0.3028912 |
| GO:BP | GO:1901873 | regulation of post-translational protein modification | 12 | BUB3,CRY1,PML,NXN,PEX12,FZR1,PIAS4,PHF20,CTBP1,NELFA,UFL1,UBE2V2 | 301 | 0.3028912 |
| GO:BP | GO:0003281 | ventricular septum development | 1 | LMO4 | 69 | 0.3028912 |
| GO:BP | GO:0034654 | nucleobase-containing compound biosynthetic process | 67 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,NPM3,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,PCF11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,LIG4,ING1,SNAPC1,BRF1,BAHD1,TRIP4,PML,PPCDC,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,TEFM,HEXIM1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324 | 3057 | 0.3028912 |
| GO:BP | GO:0002686 | negative regulation of leukocyte migration | 1 | ADORA1 | 30 | 0.3028912 |
| GO:BP | GO:0048663 | neuron fate commitment | 1 | LMO4 | 28 | 0.3028912 |
| GO:BP | GO:1904748 | regulation of apoptotic process involved in development | 1 | PML | 9 | 0.3028912 |
| GO:BP | GO:0071479 | cellular response to ionizing radiation | 2 | RAD9A,LIG4 | 64 | 0.3028912 |
| GO:BP | GO:0016192 | vesicle-mediated transport | 15 | CPLANE2,STX12,TRAPPC3,ADORA1,COG2,PPP3CB,BLOC1S2,AP2A2,VPS37C,SCYL1,ANKRD13D,C12orf4,NECAP1,MON2,RAB3IP | 1230 | 0.3028912 |
| GO:BP | GO:0007519 | skeletal muscle tissue development | 2 | PPP3CB,ANKRD1 | 128 | 0.3030809 |
| GO:BP | GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 1 | RNF19B | 99 | 0.3031371 |
| GO:BP | GO:0072488 | ammonium transmembrane transport | 1 | SLC12A4 | 6 | 0.3031682 |
| GO:BP | GO:2000629 | negative regulation of miRNA metabolic process | 2 | TENT2,PPARD | 23 | 0.3032203 |
| GO:BP | GO:0001841 | neural tube formation | 4 | LMO4,CLUAP1,MKS1,IFT52 | 98 | 0.3037049 |
| GO:BP | GO:0008298 | intracellular mRNA localization | 1 | CASC3 | 10 | 0.3040588 |
| GO:BP | GO:0071897 | DNA biosynthetic process | 5 | ANKRD1,LIG4,PML,TERF2IP,MAP2K7 | 174 | 0.3044184 |
| GO:BP | GO:0002526 | acute inflammatory response | 2 | ADORA1,GSTP1 | 50 | 0.3051635 |
| GO:BP | GO:0006703 | estrogen biosynthetic process | 1 | HSD17B1 | 6 | 0.3053598 |
| GO:BP | GO:0018130 | heterocycle biosynthetic process | 68 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,NPM3,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,PCF11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,LIG4,ING1,SNAPC1,BRF1,BAHD1,TRIP4,PML,PPCDC,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,TEFM,HEXIM1,RSAD1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324 | 3118 | 0.3067471 |
| GO:BP | GO:0035067 | negative regulation of histone acetylation | 1 | CTBP1 | 6 | 0.3067471 |
| GO:BP | GO:0032682 | negative regulation of chemokine production | 1 | GSTP1 | 12 | 0.3067471 |
| GO:BP | GO:0016049 | cell growth | 13 | PPP3CB,BDNF,EI24,ING1,PML,PAFAH1B1,RPTOR,IMPACT,SERTAD1,BCL11A,OGFR,N6AMT1,SMARCB1 | 415 | 0.3067471 |
| GO:BP | GO:2001137 | positive regulation of endocytic recycling | 1 | EIPR1 | 7 | 0.3067471 |
| GO:BP | GO:0055118 | negative regulation of cardiac muscle contraction | 1 | SRI | 4 | 0.3069307 |
| GO:BP | GO:1990089 | response to nerve growth factor | 2 | BDNF,EIF4A3 | 41 | 0.3071115 |
| GO:BP | GO:0090101 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 3 | HDAC1,BRMS1,ING1 | 122 | 0.3071115 |
| GO:BP | GO:0065009 | regulation of molecular function | 40 | PEX14,ASAP3,HDAC1,LMO4,DUSP12,TIPRL,ADORA1,AIDA,PSEN2,PPP3CB,BUB3,BDNF,SPINDOC,BRMS1,PPP1CA,GSTP1,ARAP1,TRIAP1,DIABLO,RAN,RALGAPA1,TTC8,GSKIP,PML,WDR24,ERCC4,ZFP90,TERF2IP,PAFAH1B1,INCA1,NLE1,PEX12,HEXIM1,EIF4A3,RPTOR,CHMP6,FZR1,PIAS4,MAP2K7,SYDE1 | 1903 | 0.3071115 |
| GO:BP | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 1 | TRIAP1 | 15 | 0.3071681 |
| GO:BP | GO:0000956 | nuclear-transcribed mRNA catabolic process | 4 | POLR2G,CASC3,EIF4A3,SMG9 | 120 | 0.3079003 |
| GO:BP | GO:1904292 | regulation of ERAD pathway | 1 | AQP11 | 22 | 0.3079003 |
| GO:BP | GO:0031123 | RNA 3’-end processing | 2 | CLP1,PCF11 | 92 | 0.3080555 |
| GO:BP | GO:0006189 | ‘de novo’ IMP biosynthetic process | 1 | PAICS | 6 | 0.3082189 |
| GO:BP | GO:0070266 | necroptotic process | 1 | IPMK | 34 | 0.3082189 |
| GO:BP | GO:1903170 | negative regulation of calcium ion transmembrane transport | 3 | PPP3CB,SRI,PPP3CC | 35 | 0.3082189 |
| GO:BP | GO:0043666 | regulation of phosphoprotein phosphatase activity | 1 | TIPRL | 46 | 0.3082189 |
| GO:BP | GO:0001961 | positive regulation of cytokine-mediated signaling pathway | 2 | TBK1,PAFAH1B1 | 44 | 0.3087536 |
| GO:BP | GO:0090394 | negative regulation of excitatory postsynaptic potential | 1 | EIF4A3 | 9 | 0.3087536 |
| GO:BP | GO:0099590 | neurotransmitter receptor internalization | 1 | AP2A2 | 21 | 0.3089658 |
| GO:BP | GO:0072657 | protein localization to membrane | 1 | ICMT | 530 | 0.3089658 |
| GO:BP | GO:0010226 | response to lithium ion | 1 | LIG4 | 10 | 0.3089658 |
| GO:BP | GO:0042633 | hair cycle | 1 | HDAC1 | 78 | 0.3089658 |
| GO:BP | GO:0042303 | molting cycle | 1 | HDAC1 | 78 | 0.3089658 |
| GO:BP | GO:1903169 | regulation of calcium ion transmembrane transport | 2 | PSEN2,PPP3CB | 120 | 0.3089658 |
| GO:BP | GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecules | 1 | CPLANE2 | 165 | 0.3089658 |
| GO:BP | GO:0007517 | muscle organ development | 3 | LMNA,PPP3CB,ANKRD1 | 278 | 0.3089658 |
| GO:BP | GO:0043434 | response to peptide hormone | 1 | AGTRAP | 316 | 0.3092705 |
| GO:BP | GO:1903430 | negative regulation of cell maturation | 1 | BCL11A | 4 | 0.3094562 |
| GO:BP | GO:2000171 | negative regulation of dendrite development | 1 | BCL11A | 6 | 0.3094562 |
| GO:BP | GO:1903441 | protein localization to ciliary membrane | 1 | RABEP1 | 11 | 0.3099242 |
| GO:BP | GO:0051702 | biological process involved in interaction with symbiont | 1 | HDAC1 | 81 | 0.3102067 |
| GO:BP | GO:0060612 | adipose tissue development | 2 | CDK4,HSD17B1 | 45 | 0.3103894 |
| GO:BP | GO:0001783 | B cell apoptotic process | 2 | BAK1,TRAF3IP2 | 21 | 0.3112174 |
| GO:BP | GO:0080134 | regulation of response to stress | 19 | VPS72,LMNA,ADORA1,AIDA,ANKRD1,TRIM3,KAT5,RBM14,RAD9A,GSTP1,AQP11,TBK1,CRY1,TRIAP1,KMT5A,PML,ERCC4,TERF2IP,PAFAH1B1 | 1073 | 0.3115461 |
| GO:BP | GO:0035113 | embryonic appendage morphogenesis | 1 | HDAC1 | 89 | 0.3115461 |
| GO:BP | GO:0030326 | embryonic limb morphogenesis | 1 | HDAC1 | 89 | 0.3115461 |
| GO:BP | GO:0060561 | apoptotic process involved in morphogenesis | 2 | PML,BAK1 | 21 | 0.3115461 |
| GO:BP | GO:1901800 | positive regulation of proteasomal protein catabolic process | 1 | RNF19B | 107 | 0.3115461 |
| GO:BP | GO:0050772 | positive regulation of axonogenesis | 3 | BDNF,PAFAH1B1,BCL11A | 71 | 0.3119810 |
| GO:BP | GO:0019438 | aromatic compound biosynthetic process | 68 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,NPM3,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,PCF11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,LIG4,ING1,SNAPC1,BRF1,BAHD1,TRIP4,PML,PPCDC,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,TEFM,HEXIM1,RSAD1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324 | 3119 | 0.3119810 |
| GO:BP | GO:0035556 | intracellular signal transduction | 18 | ARHGEF10L,HDAC1,TIPRL,ADORA1,AIDA,SDE2,PSEN2,PPP3CB,SYNPO2L,ANKRD1,BUB3,ARFIP2,STK33,KAT5,RBM14,RAD9A,GSTP1,ARAP1 | 2035 | 0.3119810 |
| GO:BP | GO:0009157 | deoxyribonucleoside monophosphate biosynthetic process | 1 | DGUOK | 8 | 0.3121875 |
| GO:BP | GO:0021761 | limbic system development | 1 | HDAC1 | 89 | 0.3123269 |
| GO:BP | GO:2000625 | regulation of miRNA catabolic process | 1 | TENT2 | 5 | 0.3123269 |
| GO:BP | GO:0007254 | JNK cascade | 5 | AIDA,GSTP1,PAFAH1B1,MAP2K7,MAP4K3 | 137 | 0.3123269 |
| GO:BP | GO:2000209 | regulation of anoikis | 1 | BRMS1 | 23 | 0.3123269 |
| GO:BP | GO:2000197 | regulation of ribonucleoprotein complex localization | 1 | RIOK2 | 6 | 0.3134905 |
| GO:BP | GO:0034198 | cellular response to amino acid starvation | 2 | WDR24,IMPACT | 47 | 0.3134905 |
| GO:BP | GO:1903530 | regulation of secretion by cell | 4 | CPLANE2,ADORA1,PPP3CB,ANKRD1 | 381 | 0.3134905 |
| GO:BP | GO:0007409 | axonogenesis | 4 | LYPLA2,LMO4,PPP3CB,BDNF | 350 | 0.3157821 |
| GO:BP | GO:0032870 | cellular response to hormone stimulus | 2 | AGTRAP,HDAC1 | 449 | 0.3161479 |
| GO:BP | GO:1901463 | regulation of tetrapyrrole biosynthetic process | 1 | SRRD | 7 | 0.3162898 |
| GO:BP | GO:0070453 | regulation of heme biosynthetic process | 1 | SRRD | 7 | 0.3162898 |
| GO:BP | GO:0071702 | organic substance transport | 3 | ICMT,PEX14,CPLANE2 | 2134 | 0.3166521 |
| GO:BP | GO:1905634 | regulation of protein localization to chromatin | 1 | PIAS4 | 9 | 0.3175312 |
| GO:BP | GO:0048630 | skeletal muscle tissue growth | 1 | RPS6KB1 | 8 | 0.3175312 |
| GO:BP | GO:0014889 | muscle atrophy | 1 | RPS6KB1 | 9 | 0.3175312 |
| GO:BP | GO:0044818 | mitotic G2/M transition checkpoint | 3 | FZR1,HUS1,RINT1 | 50 | 0.3184478 |
| GO:BP | GO:0048741 | skeletal muscle fiber development | 1 | PPP3CB | 29 | 0.3184478 |
| GO:BP | GO:0050850 | positive regulation of calcium-mediated signaling | 1 | PPP3CB | 22 | 0.3184478 |
| GO:BP | GO:0045721 | negative regulation of gluconeogenesis | 1 | CRY1 | 13 | 0.3184478 |
| GO:BP | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation | 1 | PICK1 | 5 | 0.3184478 |
| GO:BP | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly | 1 | ZDHHC12 | 3 | 0.3184478 |
| GO:BP | GO:1903051 | negative regulation of proteolysis involved in protein catabolic process | 2 | AQP11,PML | 62 | 0.3184478 |
| GO:BP | GO:0070884 | regulation of calcineurin-NFAT signaling cascade | 1 | PPP3CB | 32 | 0.3184478 |
| GO:BP | GO:0022038 | corpus callosum development | 2 | PAFAH1B1,NSUN5 | 21 | 0.3186985 |
| GO:BP | GO:0000722 | telomere maintenance via recombination | 1 | ERCC4 | 14 | 0.3190575 |
| GO:BP | GO:0051347 | positive regulation of transferase activity | 3 | LMO4,DUSP12,ADORA1 | 389 | 0.3204222 |
| GO:BP | GO:0051657 | maintenance of organelle location | 1 | PAFAH1B1 | 13 | 0.3204222 |
| GO:BP | GO:0001919 | regulation of receptor recycling | 1 | ARAP1 | 22 | 0.3204222 |
| GO:BP | GO:1901362 | organic cyclic compound biosynthetic process | 70 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,NPM3,ZNF195,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,EMSY,PCF11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,LIG4,ING1,SNAPC1,BRF1,BAHD1,TRIP4,PML,PPCDC,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,TEFM,HSD17B1,HEXIM1,OSBPL7,RSAD1,INTS2,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324 | 3224 | 0.3204222 |
| GO:BP | GO:0016055 | Wnt signaling pathway | 9 | HDAC1,PPP1CA,UBAC2,GSKIP,NXN,NLE1,MKS1,RAC3,PIAS4 | 378 | 0.3204222 |
| GO:BP | GO:0060538 | skeletal muscle organ development | 2 | PPP3CB,ANKRD1 | 137 | 0.3204222 |
| GO:BP | GO:0034499 | late endosome to Golgi transport | 1 | SNX12 | 5 | 0.3204222 |
| GO:BP | GO:0031060 | regulation of histone methylation | 2 | PHF20,NELFA | 27 | 0.3204222 |
| GO:BP | GO:0006412 | translation | 14 | MRPL9,JMJD4,TRIM3,POLR2G,PPP1CA,BRF1,TRIP4,PML,EFL1,CASC3,RPS6KB1,EIF4A3,IMPACT,FARSA | 657 | 0.3204507 |
| GO:BP | GO:0042797 | tRNA transcription by RNA polymerase III | 1 | GTF3C3 | 8 | 0.3205162 |
| GO:BP | GO:0051220 | cytoplasmic sequestering of protein | 2 | MAD1L1,SRI | 25 | 0.3205162 |
| GO:BP | GO:0007286 | spermatid development | 1 | PITHD1 | 108 | 0.3205162 |
| GO:BP | GO:0032507 | maintenance of protein location in cell | 2 | PML,ARL2BP | 57 | 0.3205162 |
| GO:BP | GO:0098773 | skin epidermis development | 1 | HDAC1 | 90 | 0.3206943 |
| GO:BP | GO:0030865 | cortical cytoskeleton organization | 2 | PAFAH1B1,RAC3 | 45 | 0.3211527 |
| GO:BP | GO:0106056 | regulation of calcineurin-mediated signaling | 1 | PPP3CB | 32 | 0.3211527 |
| GO:BP | GO:0032469 | endoplasmic reticulum calcium ion homeostasis | 2 | PML,BAK1 | 26 | 0.3211527 |
| GO:BP | GO:0050805 | negative regulation of synaptic transmission | 1 | ADORA1 | 35 | 0.3211527 |
| GO:BP | GO:1901185 | negative regulation of ERBB signaling pathway | 2 | CHMP6,RAB7A | 30 | 0.3211527 |
| GO:BP | GO:0007289 | spermatid nucleus differentiation | 1 | KAT5 | 16 | 0.3211527 |
| GO:BP | GO:0043401 | steroid hormone mediated signaling pathway | 3 | HDAC1,CRY1,TRIP4 | 114 | 0.3216407 |
| GO:BP | GO:1905214 | regulation of RNA binding | 1 | EIF4A3 | 11 | 0.3216407 |
| GO:BP | GO:0198738 | cell-cell signaling by wnt | 9 | HDAC1,PPP1CA,UBAC2,GSKIP,NXN,NLE1,MKS1,RAC3,PIAS4 | 379 | 0.3220416 |
| GO:BP | GO:0006825 | copper ion transport | 1 | SLC46A3 | 14 | 0.3223157 |
| GO:BP | GO:0060633 | negative regulation of transcription initiation by RNA polymerase II | 1 | ZNF451 | 6 | 0.3223157 |
| GO:BP | GO:0035646 | endosome to melanosome transport | 1 | AP1M1 | 9 | 0.3223157 |
| GO:BP | GO:0050435 | amyloid-beta metabolic process | 1 | PSEN2 | 48 | 0.3223157 |
| GO:BP | GO:1902165 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 1 | TRIAP1 | 17 | 0.3223157 |
| GO:BP | GO:0048757 | pigment granule maturation | 1 | AP1M1 | 9 | 0.3223157 |
| GO:BP | GO:0046785 | microtubule polymerization | 2 | BLOC1S2,NAV3 | 84 | 0.3223157 |
| GO:BP | GO:1904814 | regulation of protein localization to chromosome, telomeric region | 1 | PML | 15 | 0.3223157 |
| GO:BP | GO:0043485 | endosome to pigment granule transport | 1 | AP1M1 | 9 | 0.3223157 |
| GO:BP | GO:0042476 | odontogenesis | 1 | HDAC1 | 82 | 0.3223157 |
| GO:BP | GO:0090322 | regulation of superoxide metabolic process | 1 | GSTP1 | 16 | 0.3223157 |
| GO:BP | GO:0043029 | T cell homeostasis | 2 | PPP3CB,SLC39A3 | 29 | 0.3223157 |
| GO:BP | GO:0061724 | lipophagy | 1 | RAB7A | 7 | 0.3227628 |
| GO:BP | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway | 1 | TBK1 | 17 | 0.3227628 |
| GO:BP | GO:0045637 | regulation of myeloid cell differentiation | 1 | PITHD1 | 138 | 0.3227628 |
| GO:BP | GO:0060485 | mesenchyme development | 1 | CPLANE2 | 250 | 0.3227628 |
| GO:BP | GO:0051668 | localization within membrane | 1 | ICMT | 610 | 0.3227628 |
| GO:BP | GO:0043647 | inositol phosphate metabolic process | 1 | IPMK | 36 | 0.3227628 |
| GO:BP | GO:0090383 | phagosome acidification | 1 | RAB7A | 5 | 0.3227628 |
| GO:BP | GO:0021892 | cerebral cortex GABAergic interneuron differentiation | 1 | RAC3 | 3 | 0.3227628 |
| GO:BP | GO:0042795 | snRNA transcription by RNA polymerase II | 1 | SNAPC1 | 15 | 0.3229488 |
| GO:BP | GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 26 | PITHD1,HDAC1,MED8,LMO4,VPS72,ECD,PPP3CB,ANKRD1,BLOC1S2,POLR2G,KAT5,RBM14,MED17,ANKRD49,TBK1,TRIAP1,GTF2F2,ING1,BRF1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287 | 1588 | 0.3230481 |
| GO:BP | GO:0090090 | negative regulation of canonical Wnt signaling pathway | 1 | HDAC1 | 114 | 0.3230481 |
| GO:BP | GO:0071569 | protein ufmylation | 1 | UFL1 | 6 | 0.3232272 |
| GO:BP | GO:0035930 | corticosteroid hormone secretion | 1 | CRY1 | 12 | 0.3232272 |
| GO:BP | GO:0039530 | MDA-5 signaling pathway | 1 | RIOK3 | 8 | 0.3232272 |
| GO:BP | GO:0045722 | positive regulation of gluconeogenesis | 1 | CRY1 | 18 | 0.3232272 |
| GO:BP | GO:0048515 | spermatid differentiation | 1 | PITHD1 | 114 | 0.3232272 |
| GO:BP | GO:0000041 | transition metal ion transport | 3 | SLC48A1,SLC46A3,SLC39A3 | 74 | 0.3233024 |
| GO:BP | GO:0097345 | mitochondrial outer membrane permeabilization | 1 | BLOC1S2 | 35 | 0.3236382 |
| GO:BP | GO:0012501 | programmed cell death | 14 | HDAC1,VPS72,LMNA,ADORA1,PSEN2,IPMK,ANKRD1,BLOC1S2,BDNF,KAT5,BRMS1,RAD9A,PPP1CA,GSTP1 | 1499 | 0.3236382 |
| GO:BP | GO:0007020 | microtubule nucleation | 1 | BLOC1S2 | 39 | 0.3236382 |
| GO:BP | GO:0031953 | negative regulation of protein autophosphorylation | 1 | IMPACT | 8 | 0.3236382 |
| GO:BP | GO:0080090 | regulation of primary metabolic process | 100 | PEX14,PITHD1,HDAC1,RNF19B,MED8,LMO4,VPS72,LMNA,DUSP12,TIPRL,ADORA1,AIDA,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,BUB3,ZNF195,TRIM3,BDNF,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,GSTP1,EMSY,AQP11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,DIABLO,KMT5A,ZNF605,GTF2F2,ING1,GSKIP,BRF1,BAHD1,TRIP4,PML,WDR24,ERCC4,ARL2BP,E2F4,ZFP90,TERF2IP,NXN,INCA1,ZNF287,NLE1,PEX12,CASC3,HEXIM1,OSBPL7,SPOP,SRSF1,RPS6KB1,INTS2,EIF4A3,RPTOR,CHMP6,IMPACT,MIER2,MOB3A,FZR1,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,RAB1A,ZNF638,RANBP2,PSMD14,NOSTRIN,METTL8 | 4375 | 0.3236757 |
| GO:BP | GO:0051932 | synaptic transmission, GABAergic | 1 | ADORA1 | 36 | 0.3236757 |
| GO:BP | GO:0009566 | fertilization | 1 | PITHD1 | 93 | 0.3238737 |
| GO:BP | GO:0038173 | interleukin-17A-mediated signaling pathway | 1 | TRAF3IP2 | 5 | 0.3238737 |
| GO:BP | GO:0048660 | regulation of smooth muscle cell proliferation | 1 | HDAC1 | 100 | 0.3243273 |
| GO:BP | GO:0033151 | V(D)J recombination | 1 | LIG4 | 15 | 0.3243639 |
| GO:BP | GO:0009896 | positive regulation of catabolic process | 10 | RNF19B,ADORA1,POLR2G,KAT5,PAFAH1B2,TBK1,WDR24,OSBPL7,RPTOR,FZR1 | 465 | 0.3254154 |
| GO:BP | GO:0001959 | regulation of cytokine-mediated signaling pathway | 4 | GSTP1,TBK1,PAFAH1B1,PIAS4 | 118 | 0.3254629 |
| GO:BP | GO:0032008 | positive regulation of TOR signaling | 2 | WDR24,RPTOR | 47 | 0.3254984 |
| GO:BP | GO:0035306 | positive regulation of dephosphorylation | 1 | ADORA1 | 46 | 0.3256407 |
| GO:BP | GO:0048489 | synaptic vesicle transport | 1 | BLOC1S2 | 36 | 0.3256407 |
| GO:BP | GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors | 2 | BLOC1S2,DIABLO | 73 | 0.3256407 |
| GO:BP | GO:0008219 | cell death | 14 | HDAC1,VPS72,LMNA,ADORA1,PSEN2,IPMK,ANKRD1,BLOC1S2,BDNF,KAT5,BRMS1,RAD9A,PPP1CA,GSTP1 | 1505 | 0.3256407 |
| GO:BP | GO:1990928 | response to amino acid starvation | 2 | WDR24,IMPACT | 50 | 0.3256407 |
| GO:BP | GO:0009200 | deoxyribonucleoside triphosphate metabolic process | 1 | DGUOK | 9 | 0.3256407 |
| GO:BP | GO:0042759 | long-chain fatty acid biosynthetic process | 1 | GSTP1 | 13 | 0.3256407 |
| GO:BP | GO:0051972 | regulation of telomerase activity | 2 | PML,MAP2K7 | 45 | 0.3256407 |
| GO:BP | GO:0044706 | multi-multicellular organism process | 1 | PITHD1 | 136 | 0.3256407 |
| GO:BP | GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 4 | TRIAP1,DIABLO,PML,NLE1 | 143 | 0.3256407 |
| GO:BP | GO:0019752 | carboxylic acid metabolic process | 1 | ICMT | 685 | 0.3256407 |
| GO:BP | GO:0048242 | epinephrine secretion | 1 | ADRA2C | 2 | 0.3256407 |
| GO:BP | GO:0014060 | regulation of epinephrine secretion | 1 | ADRA2C | 2 | 0.3256407 |
| GO:BP | GO:0097294 | ‘de novo’ XMP biosynthetic process | 1 | PAICS | 7 | 0.3256407 |
| GO:BP | GO:0097293 | XMP biosynthetic process | 1 | PAICS | 7 | 0.3256407 |
| GO:BP | GO:0019262 | N-acetylneuraminate catabolic process | 1 | GNPDA2 | 7 | 0.3256407 |
| GO:BP | GO:0060070 | canonical Wnt signaling pathway | 6 | HDAC1,PPP1CA,UBAC2,GSKIP,NLE1,MKS1 | 253 | 0.3256407 |
| GO:BP | GO:0097292 | XMP metabolic process | 1 | PAICS | 7 | 0.3256407 |
| GO:BP | GO:1902749 | regulation of cell cycle G2/M phase transition | 5 | CDK4,FZR1,MTA3,HUS1,RINT1 | 105 | 0.3262936 |
| GO:BP | GO:0010506 | regulation of autophagy | 7 | KAT5,PAFAH1B2,TBK1,WDR24,ERCC4,OSBPL7,RPTOR | 315 | 0.3269668 |
| GO:BP | GO:0048659 | smooth muscle cell proliferation | 1 | HDAC1 | 104 | 0.3279020 |
| GO:BP | GO:0031623 | receptor internalization | 2 | AP2A2,ANKRD13D | 97 | 0.3279587 |
| GO:BP | GO:0030575 | nuclear body organization | 1 | PML | 13 | 0.3288662 |
| GO:BP | GO:0006880 | intracellular sequestering of iron ion | 1 | SRI | 4 | 0.3292581 |
| GO:BP | GO:0065004 | protein-DNA complex assembly | 8 | MED8,MED17,BRF1,MED15,SMARCB1,NAP1L5,BDP1,MED7 | 174 | 0.3298344 |
| GO:BP | GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 7 | RNF19B,PML,FZR1,BBS7,UFL1,TMEM168,PHF20L1 | 157 | 0.3298344 |
| GO:BP | GO:0051054 | positive regulation of DNA metabolic process | 9 | VPS72,KAT5,PML,TERF2IP,PIAS4,MAP2K7,INO80D,SMARCB1,ACTL6A | 267 | 0.3298433 |
| GO:BP | GO:0015866 | ADP transport | 1 | SLC35B1 | 10 | 0.3299077 |
| GO:BP | GO:0033173 | calcineurin-NFAT signaling cascade | 1 | PPP3CB | 37 | 0.3299077 |
| GO:BP | GO:0006082 | organic acid metabolic process | 1 | ICMT | 704 | 0.3299077 |
| GO:BP | GO:0010255 | glucose mediated signaling pathway | 1 | SMARCB1 | 5 | 0.3299077 |
| GO:BP | GO:0001514 | selenocysteine incorporation | 1 | EIF4A3 | 10 | 0.3299077 |
| GO:BP | GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 1 | RNF19B | 122 | 0.3299077 |
| GO:BP | GO:0090066 | regulation of anatomical structure size | 8 | ADORA1,BLOC1S2,BDNF,PPP1CA,AQP11,E2F4,SLC12A4,PAFAH1B1 | 395 | 0.3299077 |
| GO:BP | GO:1901021 | positive regulation of calcium ion transmembrane transporter activity | 1 | PPP3CB | 38 | 0.3299077 |
| GO:BP | GO:1901652 | response to peptide | 1 | AGTRAP | 368 | 0.3299077 |
| GO:BP | GO:0007034 | vacuolar transport | 6 | VPS37C,CHMP1A,CHMP6,STAM2,RAB7A,ZFYVE16 | 148 | 0.3299077 |
| GO:BP | GO:0010182 | sugar mediated signaling pathway | 1 | SMARCB1 | 5 | 0.3299077 |
| GO:BP | GO:0006451 | translational readthrough | 1 | EIF4A3 | 10 | 0.3299077 |
| GO:BP | GO:0051480 | regulation of cytosolic calcium ion concentration | 1 | ADORA1 | 39 | 0.3299077 |
| GO:BP | GO:0031396 | regulation of protein ubiquitination | 5 | BUB3,CRY1,NXN,PEX12,FZR1 | 193 | 0.3299077 |
| GO:BP | GO:0046471 | phosphatidylglycerol metabolic process | 2 | PGS1,TAMM41 | 23 | 0.3299077 |
| GO:BP | GO:0045198 | establishment of epithelial cell apical/basal polarity | 1 | TTC8 | 14 | 0.3299077 |
| GO:BP | GO:0043436 | oxoacid metabolic process | 1 | ICMT | 700 | 0.3299077 |
| GO:BP | GO:0014904 | myotube cell development | 1 | PPP3CB | 33 | 0.3299077 |
| GO:BP | GO:1901401 | regulation of tetrapyrrole metabolic process | 1 | SRRD | 8 | 0.3299077 |
| GO:BP | GO:0009757 | hexose mediated signaling | 1 | SMARCB1 | 5 | 0.3299077 |
| GO:BP | GO:0042987 | amyloid precursor protein catabolic process | 1 | PSEN2 | 53 | 0.3299077 |
| GO:BP | GO:0071233 | cellular response to leucine | 1 | RPTOR | 11 | 0.3306522 |
| GO:BP | GO:0010959 | regulation of metal ion transport | 3 | ADORA1,PSEN2,PPP3CB | 271 | 0.3306620 |
| GO:BP | GO:0006779 | porphyrin-containing compound biosynthetic process | 2 | RSAD1,SRRD | 32 | 0.3308100 |
| GO:BP | GO:0071166 | ribonucleoprotein complex localization | 1 | RIOK2 | 7 | 0.3308100 |
| GO:BP | GO:0015800 | acidic amino acid transport | 1 | ADORA1 | 39 | 0.3308100 |
| GO:BP | GO:1900244 | positive regulation of synaptic vesicle endocytosis | 1 | PPP3CC | 4 | 0.3308100 |
| GO:BP | GO:0008015 | blood circulation | 1 | AGTRAP | 372 | 0.3308100 |
| GO:BP | GO:0033014 | tetrapyrrole biosynthetic process | 2 | RSAD1,SRRD | 32 | 0.3308100 |
| GO:BP | GO:0051497 | negative regulation of stress fiber assembly | 1 | ARAP1 | 23 | 0.3308100 |
| GO:BP | GO:0001558 | regulation of cell growth | 11 | BDNF,EI24,ING1,PML,PAFAH1B1,RPTOR,SERTAD1,BCL11A,OGFR,N6AMT1,SMARCB1 | 351 | 0.3308256 |
| GO:BP | GO:0097300 | programmed necrotic cell death | 1 | IPMK | 43 | 0.3309223 |
| GO:BP | GO:0098930 | axonal transport | 2 | BLOC1S2,PAFAH1B1 | 60 | 0.3311386 |
| GO:BP | GO:0060760 | positive regulation of response to cytokine stimulus | 2 | TBK1,PAFAH1B1 | 48 | 0.3311386 |
| GO:BP | GO:1902110 | positive regulation of mitochondrial membrane permeability involved in apoptotic process | 1 | BLOC1S2 | 38 | 0.3311386 |
| GO:BP | GO:0010962 | regulation of glucan biosynthetic process | 1 | PPP1CA | 26 | 0.3311386 |
| GO:BP | GO:0005979 | regulation of glycogen biosynthetic process | 1 | PPP1CA | 26 | 0.3311386 |
| GO:BP | GO:0035722 | interleukin-12-mediated signaling pathway | 1 | STAT4 | 5 | 0.3311386 |
| GO:BP | GO:0043112 | receptor metabolic process | 3 | ARAP1,PEX12,ARFGEF2 | 67 | 0.3313048 |
| GO:BP | GO:0072594 | establishment of protein localization to organelle | 1 | PEX14 | 420 | 0.3313048 |
| GO:BP | GO:0016073 | snRNA metabolic process | 2 | SNAPC1,INTS2 | 54 | 0.3316360 |
| GO:BP | GO:0031647 | regulation of protein stability | 2 | STX12,LMNA | 293 | 0.3316360 |
| GO:BP | GO:0048261 | negative regulation of receptor-mediated endocytosis | 1 | ANKRD13D | 25 | 0.3317450 |
| GO:BP | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 3 | BDNF,TBK1,RPTOR | 68 | 0.3321698 |
| GO:BP | GO:0070050 | neuron cellular homeostasis | 1 | ADORA1 | 45 | 0.3325405 |
| GO:BP | GO:0071459 | protein localization to chromosome, centromeric region | 1 | BUB3 | 29 | 0.3325405 |
| GO:BP | GO:0033120 | positive regulation of RNA splicing | 2 | SRSF1,HNRNPLL | 34 | 0.3332500 |
| GO:BP | GO:0071333 | cellular response to glucose stimulus | 2 | PPP3CB,KAT5 | 95 | 0.3332500 |
| GO:BP | GO:0036465 | synaptic vesicle recycling | 4 | PPP3CB,SH3GL1,CTBP1,PPP3CC | 72 | 0.3332500 |
| GO:BP | GO:0033619 | membrane protein proteolysis | 1 | PSEN2 | 45 | 0.3332500 |
| GO:BP | GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 1 | RNF19B | 130 | 0.3332500 |
| GO:BP | GO:0051028 | mRNA transport | 4 | CASC3,SRSF1,EIF4A3,RANBP2 | 115 | 0.3334019 |
| GO:BP | GO:0006887 | exocytosis | 1 | CPLANE2 | 251 | 0.3334019 |
| GO:BP | GO:0021819 | layer formation in cerebral cortex | 1 | PAFAH1B1 | 12 | 0.3335772 |
| GO:BP | GO:0040013 | negative regulation of locomotion | 5 | HDAC1,ADORA1,BRMS1,NAV3,ING1 | 262 | 0.3335772 |
| GO:BP | GO:0051056 | regulation of small GTPase mediated signal transduction | 1 | ARHGEF10L | 249 | 0.3335772 |
| GO:BP | GO:0002791 | regulation of peptide secretion | 2 | ADORA1,PPP3CB | 136 | 0.3335772 |
| GO:BP | GO:0035108 | limb morphogenesis | 1 | HDAC1 | 113 | 0.3335772 |
| GO:BP | GO:0035107 | appendage morphogenesis | 1 | HDAC1 | 113 | 0.3335772 |
| GO:BP | GO:1904936 | interneuron migration | 1 | PAFAH1B1 | 6 | 0.3335772 |
| GO:BP | GO:0050885 | neuromuscular process controlling balance | 2 | PAFAH1B1,RAC3 | 35 | 0.3335772 |
| GO:BP | GO:0006622 | protein targeting to lysosome | 2 | RAB7A,ZFYVE16 | 29 | 0.3335772 |
| GO:BP | GO:0051304 | chromosome separation | 4 | BUB3,SMARCAD1,MAD1L1,SMC2 | 75 | 0.3338001 |
| GO:BP | GO:0001914 | regulation of T cell mediated cytotoxicity | 1 | PPP3CB | 23 | 0.3340303 |
| GO:BP | GO:0046602 | regulation of mitotic centrosome separation | 1 | NSFL1C | 8 | 0.3341813 |
| GO:BP | GO:0043200 | response to amino acid | 5 | RPS6KB1,RPTOR,BCL11A,CPEB4,UFL1 | 94 | 0.3341981 |
| GO:BP | GO:0051154 | negative regulation of striated muscle cell differentiation | 1 | BDNF | 30 | 0.3345667 |
| GO:BP | GO:0043065 | positive regulation of apoptotic process | 8 | ANKRD1,BRMS1,RAD9A,PPP1CA,PHLDA1,DIABLO,PML,INCA1 | 394 | 0.3345667 |
| GO:BP | GO:0043502 | regulation of muscle adaptation | 1 | LMNA | 68 | 0.3350468 |
| GO:BP | GO:0016180 | snRNA processing | 2 | INTS2,INTS8 | 26 | 0.3350677 |
| GO:BP | GO:0010032 | meiotic chromosome condensation | 1 | SMC2 | 6 | 0.3351326 |
| GO:BP | GO:0071331 | cellular response to hexose stimulus | 2 | PPP3CB,KAT5 | 96 | 0.3357116 |
| GO:BP | GO:0090087 | regulation of peptide transport | 2 | ADORA1,PPP3CB | 138 | 0.3357116 |
| GO:BP | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 1 | POLR2G | 33 | 0.3359912 |
| GO:BP | GO:0140894 | endolysosomal toll-like receptor signaling pathway | 1 | TRIM3 | 25 | 0.3361904 |
| GO:BP | GO:0006109 | regulation of carbohydrate metabolic process | 3 | DUSP12,PPP1CA,CRY1 | 147 | 0.3365252 |
| GO:BP | GO:0097720 | calcineurin-mediated signaling | 1 | PPP3CB | 38 | 0.3365252 |
| GO:BP | GO:0002252 | immune effector process | 2 | PLEKHM2,RNF19B | 324 | 0.3365252 |
| GO:BP | GO:0098703 | calcium ion import across plasma membrane | 1 | PPP3CB | 26 | 0.3365252 |
| GO:BP | GO:0051052 | regulation of DNA metabolic process | 10 | VPS72,LMNA,ANKRD1,KAT5,KMT5A,PML,ERCC4,TERF2IP,PIAS4,MAP2K7 | 458 | 0.3365252 |
| GO:BP | GO:0043085 | positive regulation of catalytic activity | 5 | ASAP3,LMO4,DUSP12,ADORA1,PSEN2 | 814 | 0.3365252 |
| GO:BP | GO:1902686 | mitochondrial outer membrane permeabilization involved in programmed cell death | 1 | BLOC1S2 | 40 | 0.3365252 |
| GO:BP | GO:0006353 | DNA-templated transcription termination | 1 | PCF11 | 22 | 0.3365252 |
| GO:BP | GO:0040016 | embryonic cleavage | 1 | TPRA1 | 7 | 0.3365252 |
| GO:BP | GO:0051648 | vesicle localization | 7 | TRAPPC3,BLOC1S2,PAFAH1B1,RAB1A,RAB7A,CTBP1,BBS7 | 195 | 0.3373213 |
| GO:BP | GO:0051291 | protein heterooligomerization | 2 | FARSA,ZNF777 | 22 | 0.3373213 |
| GO:BP | GO:0055013 | cardiac muscle cell development | 1 | LMNA | 74 | 0.3385820 |
| GO:BP | GO:0048534 | hematopoietic or lymphoid organ development | 1 | LMO4 | 71 | 0.3385820 |
| GO:BP | GO:0043547 | positive regulation of GTPase activity | 1 | ASAP3 | 211 | 0.3385820 |
| GO:BP | GO:1901135 | carbohydrate derivative metabolic process | 1 | ICMT | 843 | 0.3385820 |
| GO:BP | GO:0000423 | mitophagy | 1 | ARFIP2 | 37 | 0.3385820 |
| GO:BP | GO:0071326 | cellular response to monosaccharide stimulus | 2 | PPP3CB,KAT5 | 97 | 0.3385820 |
| GO:BP | GO:0006448 | regulation of translational elongation | 1 | EIF4A3 | 12 | 0.3385820 |
| GO:BP | GO:2000143 | negative regulation of DNA-templated transcription initiation | 1 | ZNF451 | 6 | 0.3385820 |
| GO:BP | GO:0051125 | regulation of actin nucleation | 1 | ARFIP2 | 31 | 0.3385820 |
| GO:BP | GO:0050821 | protein stabilization | 4 | STX12,RPAP3,PML,COG7 | 196 | 0.3385820 |
| GO:BP | GO:0000712 | resolution of meiotic recombination intermediates | 1 | ERCC4 | 13 | 0.3390227 |
| GO:BP | GO:1990542 | mitochondrial transmembrane transport | 1 | PSEN2 | 57 | 0.3390227 |
| GO:BP | GO:0060402 | calcium ion transport into cytosol | 2 | PML,BAK1 | 18 | 0.3391469 |
| GO:BP | GO:0008053 | mitochondrial fusion | 2 | PARL,BAK1 | 29 | 0.3391469 |
| GO:BP | GO:2000831 | regulation of steroid hormone secretion | 1 | CRY1 | 13 | 0.3391469 |
| GO:BP | GO:0006833 | water transport | 1 | AQP11 | 12 | 0.3393243 |
| GO:BP | GO:0003300 | cardiac muscle hypertrophy | 1 | LMNA | 72 | 0.3396767 |
| GO:BP | GO:0001947 | heart looping | 3 | CLUAP1,IFT52,BBS7 | 50 | 0.3396767 |
| GO:BP | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 2 | TRIAP1,NLE1 | 51 | 0.3396767 |
| GO:BP | GO:0042255 | ribosome assembly | 2 | EFL1,NLE1 | 62 | 0.3396767 |
| GO:BP | GO:1901992 | positive regulation of mitotic cell cycle phase transition | 4 | CDK4,RPTOR,MTA3,MAD1L1 | 84 | 0.3402994 |
| GO:BP | GO:0071407 | cellular response to organic cyclic compound | 10 | HDAC1,KAT5,CDK4,CRY1,RAN,SLC46A3,TRIP4,OSBPL7,RPS6KB1,RIOK3 | 407 | 0.3402994 |
| GO:BP | GO:0015936 | coenzyme A metabolic process | 1 | PPCDC | 18 | 0.3423954 |
| GO:BP | GO:0044242 | cellular lipid catabolic process | 1 | LYPLA2 | 168 | 0.3423954 |
| GO:BP | GO:1903367 | positive regulation of fear response | 1 | PRKAR1B | 4 | 0.3423954 |
| GO:BP | GO:0071396 | cellular response to lipid | 11 | HDAC1,ANKRD1,KAT5,GSTP1,CDK4,CRY1,RAN,TRIP4,OSBPL7,RPS6KB1,MAP2K7 | 400 | 0.3423954 |
| GO:BP | GO:2000765 | regulation of cytoplasmic translation | 2 | IMPACT,CPEB4 | 30 | 0.3423954 |
| GO:BP | GO:0044208 | ‘de novo’ AMP biosynthetic process | 1 | PAICS | 8 | 0.3423954 |
| GO:BP | GO:0043482 | cellular pigment accumulation | 1 | AP1M1 | 11 | 0.3423954 |
| GO:BP | GO:0048167 | regulation of synaptic plasticity | 2 | ADORA1,PPP3CB | 146 | 0.3423954 |
| GO:BP | GO:0042249 | establishment of planar polarity of embryonic epithelium | 1 | PAFAH1B1 | 15 | 0.3423954 |
| GO:BP | GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process | 1 | BLOC1S2 | 42 | 0.3423954 |
| GO:BP | GO:0009301 | snRNA transcription | 1 | SNAPC1 | 18 | 0.3423954 |
| GO:BP | GO:0032092 | positive regulation of protein binding | 2 | BDNF,RAN | 78 | 0.3423954 |
| GO:BP | GO:0032232 | negative regulation of actin filament bundle assembly | 1 | ARAP1 | 26 | 0.3423954 |
| GO:BP | GO:0043476 | pigment accumulation | 1 | AP1M1 | 11 | 0.3423954 |
| GO:BP | GO:0015074 | DNA integration | 1 | SMARCB1 | 9 | 0.3423954 |
| GO:BP | GO:0001188 | RNA polymerase I preinitiation complex assembly | 1 | SMARCB1 | 8 | 0.3423954 |
| GO:BP | GO:1990253 | cellular response to leucine starvation | 1 | IMPACT | 13 | 0.3423954 |
| GO:BP | GO:0051046 | regulation of secretion | 4 | CPLANE2,ADORA1,PPP3CB,ANKRD1 | 412 | 0.3423954 |
| GO:BP | GO:0051491 | positive regulation of filopodium assembly | 1 | ARAP1 | 25 | 0.3423954 |
| GO:BP | GO:0035794 | positive regulation of mitochondrial membrane permeability | 1 | BLOC1S2 | 42 | 0.3423954 |
| GO:BP | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport | 1 | TRAPPC3 | 118 | 0.3424347 |
| GO:BP | GO:0031669 | cellular response to nutrient levels | 8 | KAT5,PRKAB1,WDR24,RPTOR,IMPACT,PICK1,CPEB4,PPARD | 198 | 0.3426151 |
| GO:BP | GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 3 | HDAC1,RAD9A,TRIAP1 | 157 | 0.3432411 |
| GO:BP | GO:0051650 | establishment of vesicle localization | 2 | TRAPPC3,BLOC1S2 | 178 | 0.3432411 |
| GO:BP | GO:0007163 | establishment or maintenance of cell polarity | 5 | LMNA,KAT5,TTC8,PAFAH1B1,RAC3 | 198 | 0.3438369 |
| GO:BP | GO:0051168 | nuclear export | 6 | RAN,CASC3,EIF4A3,RANBP2,RIOK2,SRSF3 | 149 | 0.3443557 |
| GO:BP | GO:0006307 | DNA dealkylation involved in DNA repair | 1 | ASCC2 | 9 | 0.3445346 |
| GO:BP | GO:0043043 | peptide biosynthetic process | 14 | MRPL9,JMJD4,TRIM3,POLR2G,PPP1CA,BRF1,TRIP4,PML,EFL1,CASC3,RPS6KB1,EIF4A3,IMPACT,FARSA | 677 | 0.3445346 |
| GO:BP | GO:0009247 | glycolipid biosynthetic process | 1 | PIGC | 62 | 0.3449083 |
| GO:BP | GO:0014897 | striated muscle hypertrophy | 1 | LMNA | 73 | 0.3450410 |
| GO:BP | GO:1900101 | regulation of endoplasmic reticulum unfolded protein response | 2 | BAK1,UFL1 | 29 | 0.3453014 |
| GO:BP | GO:0038179 | neurotrophin signaling pathway | 1 | BDNF | 36 | 0.3453014 |
| GO:BP | GO:0032210 | regulation of telomere maintenance via telomerase | 2 | PML,MAP2K7 | 49 | 0.3453364 |
| GO:BP | GO:0034389 | lipid droplet organization | 1 | KAT5 | 30 | 0.3458681 |
| GO:BP | GO:0045589 | regulation of regulatory T cell differentiation | 1 | KAT5 | 21 | 0.3458681 |
| GO:BP | GO:0070316 | regulation of G0 to G1 transition | 2 | SMARCB1,ACTL6A | 33 | 0.3460977 |
| GO:BP | GO:0097577 | sequestering of iron ion | 1 | SRI | 5 | 0.3469452 |
| GO:BP | GO:0008333 | endosome to lysosome transport | 3 | CHMP1A,CHMP6,RAB7A | 63 | 0.3469452 |
| GO:BP | GO:0033235 | positive regulation of protein sumoylation | 1 | PIAS4 | 12 | 0.3469452 |
| GO:BP | GO:0032608 | interferon-beta production | 3 | TBK1,RIOK3,RNF216 | 45 | 0.3469452 |
| GO:BP | GO:0032648 | regulation of interferon-beta production | 3 | TBK1,RIOK3,RNF216 | 45 | 0.3469452 |
| GO:BP | GO:0009855 | determination of bilateral symmetry | 5 | AIDA,CLUAP1,MKS1,IFT52,BBS7 | 101 | 0.3469452 |
| GO:BP | GO:0009799 | specification of symmetry | 5 | AIDA,CLUAP1,MKS1,IFT52,BBS7 | 101 | 0.3469452 |
| GO:BP | GO:0007094 | mitotic spindle assembly checkpoint signaling | 1 | BUB3 | 43 | 0.3473314 |
| GO:BP | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus | 3 | PPP3CB,PPARD,SRI | 44 | 0.3473314 |
| GO:BP | GO:0071173 | spindle assembly checkpoint signaling | 1 | BUB3 | 43 | 0.3473314 |
| GO:BP | GO:0071174 | mitotic spindle checkpoint signaling | 1 | BUB3 | 43 | 0.3473314 |
| GO:BP | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 2 | DIABLO,PML | 63 | 0.3473314 |
| GO:BP | GO:0060759 | regulation of response to cytokine stimulus | 4 | GSTP1,TBK1,PAFAH1B1,PIAS4 | 126 | 0.3476961 |
| GO:BP | GO:0055006 | cardiac cell development | 1 | LMNA | 80 | 0.3481372 |
| GO:BP | GO:0043543 | protein acylation | 8 | VPS72,KAT5,PML,PHF20,ACTL6A,CTBP1,PHF20L1,ZDHHC12 | 192 | 0.3481372 |
| GO:BP | GO:0014896 | muscle hypertrophy | 1 | LMNA | 74 | 0.3481372 |
| GO:BP | GO:1904779 | regulation of protein localization to centrosome | 1 | NSFL1C | 10 | 0.3481372 |
| GO:BP | GO:0003279 | cardiac septum development | 1 | LMO4 | 101 | 0.3484034 |
| GO:BP | GO:0042127 | regulation of cell population proliferation | 1 | WRAP73 | 1567 | 0.3493100 |
| GO:BP | GO:0009170 | purine deoxyribonucleoside monophosphate metabolic process | 1 | DGUOK | 8 | 0.3495625 |
| GO:BP | GO:0033209 | tumor necrosis factor-mediated signaling pathway | 3 | GSTP1,TBK1,PIAS4 | 80 | 0.3495625 |
| GO:BP | GO:0044271 | cellular nitrogen compound biosynthetic process | 78 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,MRPL9,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,NPM3,ZNF195,TRIM3,ZNF408,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,EMSY,PCF11,MED17,ANKRD49,MLF2,CDK4,TBK1,CRY1,TRIAP1,KMT5A,ZNF605,GTF2F2,LIG4,ING1,SNAPC1,BRF1,BAHD1,TRIP4,PML,PPCDC,EFL1,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,TEFM,CASC3,HEXIM1,RSAD1,RPS6KB1,INTS2,EIF4A3,RPTOR,IMPACT,MIER2,PIAS4,MAP2K7,CERS4,ZNF561,ZNF440,FARSA,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324 | 3747 | 0.3495625 |
| GO:BP | GO:0030178 | negative regulation of Wnt signaling pathway | 1 | HDAC1 | 140 | 0.3495625 |
| GO:BP | GO:0036035 | osteoclast development | 1 | PAFAH1B1 | 10 | 0.3495625 |
| GO:BP | GO:0060218 | hematopoietic stem cell differentiation | 1 | KAT5 | 30 | 0.3495625 |
| GO:BP | GO:0098751 | bone cell development | 1 | PAFAH1B1 | 10 | 0.3495625 |
| GO:BP | GO:0009120 | deoxyribonucleoside metabolic process | 1 | DGUOK | 9 | 0.3495625 |
| GO:BP | GO:0071384 | cellular response to corticosteroid stimulus | 2 | RAN,RPS6KB1 | 44 | 0.3495625 |
| GO:BP | GO:0043255 | regulation of carbohydrate biosynthetic process | 2 | PPP1CA,CRY1 | 79 | 0.3495625 |
| GO:BP | GO:0032261 | purine nucleotide salvage | 1 | DGUOK | 10 | 0.3495625 |
| GO:BP | GO:0086003 | cardiac muscle cell contraction | 1 | ADORA1 | 67 | 0.3495625 |
| GO:BP | GO:0061003 | positive regulation of dendritic spine morphogenesis | 1 | PAFAH1B1 | 16 | 0.3495625 |
| GO:BP | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity | 1 | CHMP6 | 13 | 0.3495625 |
| GO:BP | GO:0031577 | spindle checkpoint signaling | 1 | BUB3 | 44 | 0.3499907 |
| GO:BP | GO:1902254 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator | 1 | TRIAP1 | 22 | 0.3501241 |
| GO:BP | GO:0003013 | circulatory system process | 1 | AGTRAP | 445 | 0.3504780 |
| GO:BP | GO:1905710 | positive regulation of membrane permeability | 1 | BLOC1S2 | 43 | 0.3506003 |
| GO:BP | GO:0032897 | negative regulation of viral transcription | 1 | HEXIM1 | 15 | 0.3510490 |
| GO:BP | GO:0043276 | anoikis | 1 | BRMS1 | 32 | 0.3517310 |
| GO:BP | GO:0009267 | cellular response to starvation | 6 | KAT5,WDR24,RPTOR,IMPACT,PICK1,CPEB4 | 148 | 0.3519624 |
| GO:BP | GO:2000008 | regulation of protein localization to cell surface | 1 | BDNF | 37 | 0.3522324 |
| GO:BP | GO:0071397 | cellular response to cholesterol | 1 | OSBPL7 | 12 | 0.3524055 |
| GO:BP | GO:0044088 | regulation of vacuole organization | 1 | PPP3CB | 51 | 0.3532880 |
| GO:BP | GO:0014874 | response to stimulus involved in regulation of muscle adaptation | 1 | RPS6KB1 | 13 | 0.3537509 |
| GO:BP | GO:0045841 | negative regulation of mitotic metaphase/anaphase transition | 1 | BUB3 | 45 | 0.3537509 |
| GO:BP | GO:2000816 | negative regulation of mitotic sister chromatid separation | 1 | BUB3 | 45 | 0.3537509 |
| GO:BP | GO:0033046 | negative regulation of sister chromatid segregation | 1 | BUB3 | 45 | 0.3537509 |
| GO:BP | GO:0060537 | muscle tissue development | 3 | LMNA,PPP3CB,ANKRD1 | 346 | 0.3537509 |
| GO:BP | GO:0033048 | negative regulation of mitotic sister chromatid segregation | 1 | BUB3 | 45 | 0.3537509 |
| GO:BP | GO:0072583 | clathrin-dependent endocytosis | 1 | AP2A2 | 43 | 0.3537509 |
| GO:BP | GO:0032727 | positive regulation of interferon-alpha production | 1 | TBK1 | 17 | 0.3537779 |
| GO:BP | GO:0016310 | phosphorylation | 27 | LMO4,DUSP12,ADORA1,AIDA,IPMK,PPP3CB,STK33,BDNF,CLP1,SCYL1,GSTP1,CDK4,TBK1,PRKAB1,GSKIP,WDR24,ARL2BP,TERF2IP,INCA1,HEXIM1,RPS6KB1,RPTOR,CHMP6,RIOK3,IMPACT,MOB3A,MAP2K7 | 1339 | 0.3537779 |
| GO:BP | GO:0051604 | protein maturation | 3 | CPLANE2,SDE2,PSEN2 | 442 | 0.3539107 |
| GO:BP | GO:0051298 | centrosome duplication | 2 | RBM14,CHMP1A | 68 | 0.3539107 |
| GO:BP | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response | 1 | BAK1 | 7 | 0.3545638 |
| GO:BP | GO:0050795 | regulation of behavior | 1 | ADORA1 | 41 | 0.3545638 |
| GO:BP | GO:0055117 | regulation of cardiac muscle contraction | 1 | ADORA1 | 69 | 0.3545638 |
| GO:BP | GO:0048050 | post-embryonic eye morphogenesis | 1 | BAK1 | 7 | 0.3545638 |
| GO:BP | GO:0051172 | negative regulation of nitrogen compound metabolic process | 36 | PEX14,HDAC1,LMO4,VPS72,TIPRL,AIDA,SUV39H2,ANKRD1,BUB3,TRIM3,POLR2G,SPINDOC,KAT5,BRMS1,GSTP1,AQP11,CRY1,TRIAP1,KMT5A,ING1,GSKIP,BAHD1,PML,ERCC4,ZFP90,TERF2IP,NXN,INCA1,NLE1,HEXIM1,EIF4A3,CHMP6,IMPACT,MIER2,PIAS4,ZNF440 | 1832 | 0.3545638 |
| GO:BP | GO:0045834 | positive regulation of lipid metabolic process | 2 | ADORA1,KAT5 | 108 | 0.3545638 |
| GO:BP | GO:0043416 | regulation of skeletal muscle tissue regeneration | 1 | PPARD | 4 | 0.3545638 |
| GO:BP | GO:0002707 | negative regulation of lymphocyte mediated immunity | 1 | PPP3CB | 24 | 0.3545638 |
| GO:BP | GO:0034968 | histone lysine methylation | 3 | SUV39H2,PHF20,NELFA | 65 | 0.3545638 |
| GO:BP | GO:0031077 | post-embryonic camera-type eye development | 1 | BAK1 | 7 | 0.3545638 |
| GO:BP | GO:0010906 | regulation of glucose metabolic process | 2 | DUSP12,CRY1 | 85 | 0.3545638 |
| GO:BP | GO:0001913 | T cell mediated cytotoxicity | 1 | PPP3CB | 29 | 0.3545638 |
| GO:BP | GO:0007585 | respiratory gaseous exchange by respiratory system | 1 | ADORA1 | 48 | 0.3545638 |
| GO:BP | GO:0043470 | regulation of carbohydrate catabolic process | 2 | PPP1CA,RPTOR | 51 | 0.3546205 |
| GO:BP | GO:0045947 | negative regulation of translational initiation | 1 | PML | 18 | 0.3552182 |
| GO:BP | GO:2001267 | regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | 1 | NLE1 | 13 | 0.3552182 |
| GO:BP | GO:0071322 | cellular response to carbohydrate stimulus | 2 | PPP3CB,KAT5 | 106 | 0.3552182 |
| GO:BP | GO:0070873 | regulation of glycogen metabolic process | 1 | PPP1CA | 29 | 0.3552182 |
| GO:BP | GO:0010921 | regulation of phosphatase activity | 1 | TIPRL | 64 | 0.3553960 |
| GO:BP | GO:0043068 | positive regulation of programmed cell death | 8 | ANKRD1,BRMS1,RAD9A,PPP1CA,PHLDA1,DIABLO,PML,INCA1 | 403 | 0.3560146 |
| GO:BP | GO:0008089 | anterograde axonal transport | 1 | BLOC1S2 | 46 | 0.3560226 |
| GO:BP | GO:0061564 | axon development | 4 | LYPLA2,LMO4,PPP3CB,BDNF | 388 | 0.3564233 |
| GO:BP | GO:1901072 | glucosamine-containing compound catabolic process | 1 | GNPDA2 | 5 | 0.3564233 |
| GO:BP | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process | 1 | GNPDA2 | 9 | 0.3564233 |
| GO:BP | GO:0071392 | cellular response to estradiol stimulus | 1 | KAT5 | 25 | 0.3564233 |
| GO:BP | GO:0071349 | cellular response to interleukin-12 | 1 | STAT4 | 7 | 0.3564233 |
| GO:BP | GO:1901838 | positive regulation of transcription of nucleolar large rRNA by RNA polymerase I | 1 | SMARCB1 | 10 | 0.3566363 |
| GO:BP | GO:0009756 | carbohydrate mediated signaling | 1 | SMARCB1 | 6 | 0.3566363 |
| GO:BP | GO:0061097 | regulation of protein tyrosine kinase activity | 1 | ADORA1 | 61 | 0.3579421 |
| GO:BP | GO:0072359 | circulatory system development | 6 | CPLANE2,LMO4,LMNA,PPP3CB,SYNPO2L,ANKRD1 | 888 | 0.3579421 |
| GO:BP | GO:0045023 | G0 to G1 transition | 2 | SMARCB1,ACTL6A | 34 | 0.3579421 |
| GO:BP | GO:0010830 | regulation of myotube differentiation | 1 | BDNF | 31 | 0.3579421 |
| GO:BP | GO:0051985 | negative regulation of chromosome segregation | 1 | BUB3 | 46 | 0.3579421 |
| GO:BP | GO:0045892 | negative regulation of DNA-templated transcription | 9 | PEX14,HDAC1,LMO4,VPS72,SUV39H2,ANKRD1,SPINDOC,KAT5,BRMS1 | 1004 | 0.3579421 |
| GO:BP | GO:0048671 | negative regulation of collateral sprouting | 1 | BCL11A | 10 | 0.3579421 |
| GO:BP | GO:0031401 | positive regulation of protein modification process | 15 | ADORA1,BDNF,KAT5,BRMS1,TBK1,CRY1,PML,WDR24,ARL2BP,PEX12,RPTOR,MOB3A,FZR1,PIAS4,MAP2K7 | 662 | 0.3579421 |
| GO:BP | GO:0017183 | protein histidyl modification to diphthamide | 1 | DPH7 | 7 | 0.3579421 |
| GO:BP | GO:0032890 | regulation of organic acid transport | 1 | ADORA1 | 48 | 0.3579421 |
| GO:BP | GO:1902100 | negative regulation of metaphase/anaphase transition of cell cycle | 1 | BUB3 | 46 | 0.3579421 |
| GO:BP | GO:2000095 | regulation of Wnt signaling pathway, planar cell polarity pathway | 1 | MKS1 | 15 | 0.3579421 |
| GO:BP | GO:0048755 | branching morphogenesis of a nerve | 1 | BCL11A | 9 | 0.3579421 |
| GO:BP | GO:1905819 | negative regulation of chromosome separation | 1 | BUB3 | 46 | 0.3579421 |
| GO:BP | GO:0030308 | negative regulation of cell growth | 5 | EI24,ING1,PML,SERTAD1,BCL11A | 161 | 0.3579421 |
| GO:BP | GO:1900182 | positive regulation of protein localization to nucleus | 2 | PPP3CB,RAN | 81 | 0.3579421 |
| GO:BP | GO:0038202 | TORC1 signaling | 2 | WDR24,RPTOR | 60 | 0.3579421 |
| GO:BP | GO:0002447 | eosinophil mediated immunity | 1 | TRAF3IP2 | 5 | 0.3579421 |
| GO:BP | GO:0045927 | positive regulation of growth | 7 | BDNF,PAFAH1B1,RPS6KB1,RPTOR,BCL11A,N6AMT1,SMARCB1 | 196 | 0.3579421 |
| GO:BP | GO:0071222 | cellular response to lipopolysaccharide | 3 | ANKRD1,GSTP1,CDK4 | 114 | 0.3579421 |
| GO:BP | GO:0032885 | regulation of polysaccharide biosynthetic process | 1 | PPP1CA | 32 | 0.3579421 |
| GO:BP | GO:0042274 | ribosomal small subunit biogenesis | 4 | UTP6,RIOK3,RIOK2,SRFBP1 | 102 | 0.3582534 |
| GO:BP | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity | 1 | PRKAR1B | 8 | 0.3582534 |
| GO:BP | GO:0043652 | engulfment of apoptotic cell | 1 | RAC3 | 8 | 0.3582534 |
| GO:BP | GO:0045066 | regulatory T cell differentiation | 1 | KAT5 | 22 | 0.3582534 |
| GO:BP | GO:0019432 | triglyceride biosynthetic process | 1 | KAT5 | 32 | 0.3582534 |
| GO:BP | GO:0002823 | negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 1 | PPP3CB | 26 | 0.3582534 |
| GO:BP | GO:0051173 | positive regulation of nitrogen compound metabolic process | 45 | PITHD1,HDAC1,RNF19B,MED8,LMO4,VPS72,ADORA1,JMJD4,ECD,PPP3CB,ANKRD1,BLOC1S2,BDNF,POLR2G,KAT5,BRMS1,RBM14,MED17,ANKRD49,TBK1,CRY1,TRIAP1,DIABLO,GTF2F2,ING1,BRF1,TRIP4,PML,WDR24,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,PEX12,OSBPL7,SRSF1,RPS6KB1,EIF4A3,RPTOR,IMPACT,MOB3A,FZR1,PIAS4,MAP2K7 | 2366 | 0.3582534 |
| GO:BP | GO:0070887 | cellular response to chemical stimulus | 2 | PEX14,AGTRAP | 1856 | 0.3582534 |
| GO:BP | GO:0051126 | negative regulation of actin nucleation | 1 | PICK1 | 6 | 0.3582534 |
| GO:BP | GO:0043045 | post-fertilization epigenetic regulation of gene expression | 1 | PICK1 | 7 | 0.3582534 |
| GO:BP | GO:0055064 | chloride ion homeostasis | 1 | SLC12A4 | 12 | 0.3582534 |
| GO:BP | GO:0044342 | type B pancreatic cell proliferation | 1 | CDK4 | 24 | 0.3582944 |
| GO:BP | GO:0046173 | polyol biosynthetic process | 1 | IPMK | 47 | 0.3586047 |
| GO:BP | GO:0043270 | positive regulation of monoatomic ion transport | 2 | ADORA1,PPP3CB | 151 | 0.3586047 |
| GO:BP | GO:0003002 | regionalization | 1 | CPLANE2 | 271 | 0.3596171 |
| GO:BP | GO:2000001 | regulation of DNA damage checkpoint | 1 | CRY1 | 24 | 0.3598439 |
| GO:BP | GO:0071417 | cellular response to organonitrogen compound | 1 | AGTRAP | 472 | 0.3598439 |
| GO:BP | GO:0032211 | negative regulation of telomere maintenance via telomerase | 1 | PML | 19 | 0.3598439 |
| GO:BP | GO:0051966 | regulation of synaptic transmission, glutamatergic | 1 | ADORA1 | 46 | 0.3598439 |
| GO:BP | GO:0043304 | regulation of mast cell degranulation | 1 | C12orf4 | 19 | 0.3598439 |
| GO:BP | GO:0051179 | localization | 4 | ICMT,PEX14,PLEKHM2,CPLANE2 | 3982 | 0.3598439 |
| GO:BP | GO:0030334 | regulation of cell migration | 4 | HDAC1,LMO4,LMNA,ADORA1 | 706 | 0.3598439 |
| GO:BP | GO:0033365 | protein localization to organelle | 16 | PEX14,IPO13,LMNA,PPP3CB,BUB3,VPS37C,RAB3IP,RAN,UBAC2,ING1,PML,COG7,ARL2BP,TERF2IP,RABEP1,PEX12 | 862 | 0.3598439 |
| GO:BP | GO:0001782 | B cell homeostasis | 2 | BAK1,TRAF3IP2 | 24 | 0.3598439 |
| GO:BP | GO:0019058 | viral life cycle | 9 | VPS37C,CHMP1A,CHMP6,RAB1A,SMARCB1,SPCS1,TMEM39A,RAB7A,CTBP1 | 245 | 0.3598439 |
| GO:BP | GO:0009057 | macromolecule catabolic process | 22 | PITHD1,LYPLA2,RNF19B,HERC4,TRIM3,VPS37C,POLR2G,KAT5,PPP1CA,AQP11,UBAC2,ABHD13,TRIP4,PML,CHMP1A,PEX12,CASC3,OSBPL7,SPOP,EIF4A3,CHMP6,FZR1 | 1213 | 0.3598439 |
| GO:BP | GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 1 | ADORA1 | 37 | 0.3598439 |
| GO:BP | GO:0006915 | apoptotic process | 13 | HDAC1,VPS72,LMNA,ADORA1,PSEN2,ANKRD1,BLOC1S2,BDNF,KAT5,BRMS1,RAD9A,PPP1CA,GSTP1 | 1453 | 0.3600541 |
| GO:BP | GO:1903649 | regulation of cytoplasmic transport | 2 | EIPR1,SNX12 | 27 | 0.3601401 |
| GO:BP | GO:0033313 | meiotic cell cycle checkpoint signaling | 1 | HUS1 | 6 | 0.3601401 |
| GO:BP | GO:0035089 | establishment of apical/basal cell polarity | 1 | TTC8 | 18 | 0.3601401 |
| GO:BP | GO:0001678 | intracellular glucose homeostasis | 2 | PPP3CB,KAT5 | 112 | 0.3604845 |
| GO:BP | GO:0044458 | motile cilium assembly | 2 | E2F4,MKS1 | 46 | 0.3604845 |
| GO:BP | GO:0016241 | regulation of macroautophagy | 3 | PAFAH1B2,TBK1,WDR24 | 149 | 0.3604845 |
| GO:BP | GO:0031331 | positive regulation of cellular catabolic process | 5 | POLR2G,KAT5,PAFAH1B2,TBK1,WDR24 | 282 | 0.3613926 |
| GO:BP | GO:1901532 | regulation of hematopoietic progenitor cell differentiation | 1 | KAT5 | 34 | 0.3613926 |
| GO:BP | GO:0019233 | sensory perception of pain | 1 | ADORA1 | 39 | 0.3613926 |
| GO:BP | GO:0007026 | negative regulation of microtubule depolymerization | 1 | NAV3 | 25 | 0.3617152 |
| GO:BP | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator | 2 | TRIAP1,PML | 78 | 0.3617152 |
| GO:BP | GO:1905820 | positive regulation of chromosome separation | 2 | MAD1L1,SMC2 | 28 | 0.3617152 |
| GO:BP | GO:0045988 | negative regulation of striated muscle contraction | 1 | SRI | 7 | 0.3622664 |
| GO:BP | GO:0042982 | amyloid precursor protein metabolic process | 1 | PSEN2 | 70 | 0.3633667 |
| GO:BP | GO:0090382 | phagosome maturation | 2 | RAB7A,RAB14 | 24 | 0.3641662 |
| GO:BP | GO:0015914 | phospholipid transport | 2 | GLTP,TRIAP1 | 72 | 0.3641878 |
| GO:BP | GO:1902679 | negative regulation of RNA biosynthetic process | 9 | PEX14,HDAC1,LMO4,VPS72,SUV39H2,ANKRD1,SPINDOC,KAT5,BRMS1 | 1013 | 0.3641878 |
| GO:BP | GO:0008654 | phospholipid biosynthetic process | 2 | PIGC,IPMK | 231 | 0.3641878 |
| GO:BP | GO:0034314 | Arp2/3 complex-mediated actin nucleation | 1 | ARFIP2 | 40 | 0.3652892 |
| GO:BP | GO:0045089 | positive regulation of innate immune response | 4 | TRIM3,KAT5,RBM14,TBK1 | 206 | 0.3653664 |
| GO:BP | GO:0061371 | determination of heart left/right asymmetry | 3 | CLUAP1,IFT52,BBS7 | 52 | 0.3653727 |
| GO:BP | GO:0097479 | synaptic vesicle localization | 1 | BLOC1S2 | 50 | 0.3653727 |
| GO:BP | GO:0003143 | embryonic heart tube morphogenesis | 3 | CLUAP1,IFT52,BBS7 | 56 | 0.3653727 |
| GO:BP | GO:1905150 | regulation of voltage-gated sodium channel activity | 1 | TMEM168 | 6 | 0.3657866 |
| GO:BP | GO:0035929 | steroid hormone secretion | 1 | CRY1 | 18 | 0.3657866 |
| GO:BP | GO:0048738 | cardiac muscle tissue development | 2 | LMNA,ANKRD1 | 202 | 0.3657866 |
| GO:BP | GO:0090207 | regulation of triglyceride metabolic process | 1 | KAT5 | 28 | 0.3658480 |
| GO:BP | GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway | 2 | RAD9A,PIAS4 | 52 | 0.3658480 |
| GO:BP | GO:2000671 | regulation of motor neuron apoptotic process | 1 | MAP2K7 | 12 | 0.3658496 |
| GO:BP | GO:1990403 | embryonic brain development | 1 | MKS1 | 13 | 0.3658496 |
| GO:BP | GO:0002320 | lymphoid progenitor cell differentiation | 1 | LIG4 | 17 | 0.3661014 |
| GO:BP | GO:0001838 | embryonic epithelial tube formation | 3 | LMO4,CLUAP1,MKS1 | 113 | 0.3661014 |
| GO:BP | GO:2000766 | negative regulation of cytoplasmic translation | 1 | CPEB4 | 9 | 0.3662933 |
| GO:BP | GO:0006664 | glycolipid metabolic process | 2 | PIGC,GLTP | 89 | 0.3662933 |
| GO:BP | GO:1903423 | positive regulation of synaptic vesicle recycling | 1 | PPP3CC | 6 | 0.3668418 |
| GO:BP | GO:0021543 | pallium development | 1 | HDAC1 | 146 | 0.3668418 |
| GO:BP | GO:0060444 | branching involved in mammary gland duct morphogenesis | 1 | PML | 20 | 0.3671931 |
| GO:BP | GO:0070671 | response to interleukin-12 | 1 | STAT4 | 8 | 0.3676209 |
| GO:BP | GO:0002230 | positive regulation of defense response to virus by host | 2 | PML,TRAF3IP2 | 23 | 0.3679075 |
| GO:BP | GO:0006390 | mitochondrial transcription | 1 | TEFM | 19 | 0.3679075 |
| GO:BP | GO:1901565 | organonitrogen compound catabolic process | 3 | PITHD1,LYPLA2,RNF19B | 1151 | 0.3679075 |
| GO:BP | GO:2000757 | negative regulation of peptidyl-lysine acetylation | 1 | CTBP1 | 10 | 0.3682280 |
| GO:BP | GO:0044093 | positive regulation of molecular function | 6 | ASAP3,HDAC1,LMO4,DUSP12,ADORA1,PSEN2 | 1130 | 0.3682280 |
| GO:BP | GO:0009755 | hormone-mediated signaling pathway | 1 | HDAC1 | 141 | 0.3682280 |
| GO:BP | GO:1902523 | positive regulation of protein K63-linked ubiquitination | 1 | UBE2V2 | 6 | 0.3682280 |
| GO:BP | GO:0044539 | long-chain fatty acid import into cell | 1 | RPS6KB1 | 14 | 0.3682280 |
| GO:BP | GO:1901699 | cellular response to nitrogen compound | 1 | AGTRAP | 502 | 0.3682280 |
| GO:BP | GO:0008088 | axo-dendritic transport | 2 | BLOC1S2,PAFAH1B1 | 72 | 0.3682280 |
| GO:BP | GO:0048585 | negative regulation of response to stimulus | 21 | HDAC1,LMNA,ADORA1,AIDA,HERC4,PPP3CB,BDNF,KAT5,BRMS1,GSTP1,AQP11,CRY1,TRIAP1,KMT5A,UBAC2,ING1,WDR24,ERCC4,NXN,PAFAH1B1,NLE1 | 1266 | 0.3682280 |
| GO:BP | GO:0046579 | positive regulation of Ras protein signal transduction | 1 | SYNPO2L | 42 | 0.3682280 |
| GO:BP | GO:1903509 | liposaccharide metabolic process | 2 | PIGC,GLTP | 89 | 0.3682865 |
| GO:BP | GO:0006361 | transcription initiation at RNA polymerase I promoter | 1 | SMARCB1 | 10 | 0.3683391 |
| GO:BP | GO:0051290 | protein heterotetramerization | 1 | FARSA | 12 | 0.3686131 |
| GO:BP | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration | 1 | BAK1 | 9 | 0.3690874 |
| GO:BP | GO:0015867 | ATP transport | 1 | SLC35B1 | 12 | 0.3693516 |
| GO:BP | GO:0046626 | regulation of insulin receptor signaling pathway | 2 | CDK4,RPS6KB1 | 53 | 0.3695818 |
| GO:BP | GO:0033006 | regulation of mast cell activation involved in immune response | 1 | C12orf4 | 20 | 0.3695818 |
| GO:BP | GO:1901163 | regulation of trophoblast cell migration | 1 | SYDE1 | 12 | 0.3695818 |
| GO:BP | GO:0002820 | negative regulation of adaptive immune response | 1 | PPP3CB | 27 | 0.3699652 |
| GO:BP | GO:0046902 | regulation of mitochondrial membrane permeability | 1 | BLOC1S2 | 53 | 0.3701195 |
| GO:BP | GO:0009113 | purine nucleobase biosynthetic process | 1 | PAICS | 10 | 0.3703671 |
| GO:BP | GO:0003231 | cardiac ventricle development | 1 | LMO4 | 115 | 0.3703671 |
| GO:BP | GO:0070861 | regulation of protein exit from endoplasmic reticulum | 1 | UBAC2 | 22 | 0.3707486 |
| GO:BP | GO:0042554 | superoxide anion generation | 1 | GSTP1 | 18 | 0.3712003 |
| GO:BP | GO:0071219 | cellular response to molecule of bacterial origin | 3 | ANKRD1,GSTP1,CDK4 | 118 | 0.3719328 |
| GO:BP | GO:0042325 | regulation of phosphorylation | 18 | LMO4,DUSP12,ADORA1,AIDA,BDNF,GSTP1,TBK1,GSKIP,WDR24,ARL2BP,TERF2IP,INCA1,HEXIM1,RPTOR,CHMP6,IMPACT,MOB3A,MAP2K7 | 841 | 0.3719973 |
| GO:BP | GO:0055008 | cardiac muscle tissue morphogenesis | 1 | ANKRD1 | 55 | 0.3720034 |
| GO:BP | GO:0006111 | regulation of gluconeogenesis | 2 | CRY1,RANBP2 | 42 | 0.3721042 |
| GO:BP | GO:0043500 | muscle adaptation | 1 | LMNA | 89 | 0.3728329 |
| GO:BP | GO:0051261 | protein depolymerization | 3 | CCSAP,NAV3,SH3GL1 | 100 | 0.3735109 |
| GO:BP | GO:0055081 | monoatomic anion homeostasis | 1 | SLC12A4 | 13 | 0.3736032 |
| GO:BP | GO:1905821 | positive regulation of chromosome condensation | 1 | SMC2 | 8 | 0.3736189 |
| GO:BP | GO:0019220 | regulation of phosphate metabolic process | 5 | LMO4,DUSP12,TIPRL,ADORA1,AIDA | 949 | 0.3740198 |
| GO:BP | GO:1904427 | positive regulation of calcium ion transmembrane transport | 4 | PPP3CB,BAK1,SRI,PPP3CC | 59 | 0.3744248 |
| GO:BP | GO:0045839 | negative regulation of mitotic nuclear division | 1 | BUB3 | 53 | 0.3744248 |
| GO:BP | GO:0051174 | regulation of phosphorus metabolic process | 5 | LMO4,DUSP12,TIPRL,ADORA1,AIDA | 950 | 0.3744248 |
| GO:BP | GO:0007099 | centriole replication | 1 | RBM14 | 38 | 0.3744248 |
| GO:BP | GO:0061162 | establishment of monopolar cell polarity | 1 | TTC8 | 20 | 0.3744248 |
| GO:BP | GO:1902116 | negative regulation of organelle assembly | 1 | RBM14 | 38 | 0.3744248 |
| GO:BP | GO:0007389 | pattern specification process | 1 | CPLANE2 | 304 | 0.3747013 |
| GO:BP | GO:0000209 | protein polyubiquitination | 9 | RNF19B,TRIM3,PEX12,SPOP,FZR1,MKRN2,TRAF3IP2,RNF216,UBE2V2 | 238 | 0.3747013 |
| GO:BP | GO:0033002 | muscle cell proliferation | 1 | HDAC1 | 153 | 0.3747139 |
| GO:BP | GO:2000136 | regulation of cell proliferation involved in heart morphogenesis | 1 | MKS1 | 17 | 0.3747326 |
| GO:BP | GO:0021953 | central nervous system neuron differentiation | 4 | LMO4,SCYL1,PAFAH1B1,RAC3 | 112 | 0.3748678 |
| GO:BP | GO:0043066 | negative regulation of apoptotic process | 4 | HDAC1,LMNA,ADORA1,PSEN2 | 662 | 0.3753137 |
| GO:BP | GO:0006406 | mRNA export from nucleus | 3 | CASC3,EIF4A3,SRSF3 | 60 | 0.3761417 |
| GO:BP | GO:0042044 | fluid transport | 1 | AQP11 | 19 | 0.3762561 |
| GO:BP | GO:1903651 | positive regulation of cytoplasmic transport | 1 | EIPR1 | 13 | 0.3766860 |
| GO:BP | GO:0045185 | maintenance of protein location | 4 | PML,ARL2BP,MAD1L1,SRI | 84 | 0.3766860 |
| GO:BP | GO:0032369 | negative regulation of lipid transport | 1 | CRY1 | 20 | 0.3772633 |
| GO:BP | GO:0007589 | body fluid secretion | 1 | ADORA1 | 58 | 0.3774406 |
| GO:BP | GO:0016042 | lipid catabolic process | 4 | LYPLA2,ADORA1,PAFAH1B2,CDK4 | 224 | 0.3777019 |
| GO:BP | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | 3 | FZR1,HUS1,RINT1 | 60 | 0.3778314 |
| GO:BP | GO:0098974 | postsynaptic actin cytoskeleton organization | 1 | RAC3 | 14 | 0.3778314 |
| GO:BP | GO:0043087 | regulation of GTPase activity | 1 | ASAP3 | 288 | 0.3778314 |
| GO:BP | GO:1901977 | negative regulation of cell cycle checkpoint | 1 | MAD1L1 | 7 | 0.3781409 |
| GO:BP | GO:2000234 | positive regulation of rRNA processing | 1 | RIOK2 | 10 | 0.3781409 |
| GO:BP | GO:0017156 | calcium-ion regulated exocytosis | 1 | PPP3CB | 46 | 0.3782075 |
| GO:BP | GO:0051926 | negative regulation of calcium ion transport | 1 | PPP3CB | 45 | 0.3782075 |
| GO:BP | GO:0006662 | glycerol ether metabolic process | 1 | PAFAH1B1 | 17 | 0.3798156 |
| GO:BP | GO:0046485 | ether lipid metabolic process | 1 | PAFAH1B1 | 17 | 0.3798156 |
| GO:BP | GO:0071496 | cellular response to external stimulus | 10 | ANKRD1,KAT5,PRKAB1,WDR24,RPTOR,IMPACT,PICK1,CPEB4,BAK1,PPARD | 271 | 0.3798156 |
| GO:BP | GO:2000756 | regulation of peptidyl-lysine acetylation | 2 | PML,CTBP1 | 39 | 0.3798156 |
| GO:BP | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 3 | INCA1,HEXIM1,SERTAD1 | 83 | 0.3804194 |
| GO:BP | GO:0006403 | RNA localization | 5 | RAN,CASC3,SRSF1,EIF4A3,RANBP2 | 177 | 0.3804194 |
| GO:BP | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | 1 | E2F4 | 20 | 0.3804194 |
| GO:BP | GO:0001754 | eye photoreceptor cell differentiation | 2 | TTC8,RDH13 | 30 | 0.3804978 |
| GO:BP | GO:0061450 | trophoblast cell migration | 1 | SYDE1 | 13 | 0.3811185 |
| GO:BP | GO:0001101 | response to acid chemical | 5 | RPS6KB1,RPTOR,BCL11A,CPEB4,UFL1 | 103 | 0.3811185 |
| GO:BP | GO:0002704 | negative regulation of leukocyte mediated immunity | 1 | PPP3CB | 27 | 0.3811185 |
| GO:BP | GO:0043473 | pigmentation | 4 | BLOC1S2,AP1M1,RAB1A,BBS7 | 92 | 0.3811185 |
| GO:BP | GO:0002244 | hematopoietic progenitor cell differentiation | 5 | KAT5,LIG4,ARMC6,TENT2,UFL1 | 108 | 0.3811185 |
| GO:BP | GO:0030859 | polarized epithelial cell differentiation | 1 | TTC8 | 20 | 0.3814747 |
| GO:BP | GO:2000758 | positive regulation of peptidyl-lysine acetylation | 1 | PML | 22 | 0.3814747 |
| GO:BP | GO:0061339 | establishment or maintenance of monopolar cell polarity | 1 | TTC8 | 20 | 0.3814747 |
| GO:BP | GO:0032881 | regulation of polysaccharide metabolic process | 1 | PPP1CA | 35 | 0.3815426 |
| GO:BP | GO:0002790 | peptide secretion | 2 | ADORA1,PPP3CB | 172 | 0.3826631 |
| GO:BP | GO:2000116 | regulation of cysteine-type endopeptidase activity | 4 | TRIAP1,DIABLO,PML,NLE1 | 159 | 0.3828553 |
| GO:BP | GO:0032387 | negative regulation of intracellular transport | 3 | UBAC2,RAB23,SNX12 | 48 | 0.3833126 |
| GO:BP | GO:0006497 | protein lipidation | 1 | PIGC | 89 | 0.3833126 |
| GO:BP | GO:0046782 | regulation of viral transcription | 1 | HEXIM1 | 19 | 0.3833126 |
| GO:BP | GO:0042073 | intraciliary transport | 2 | CLUAP1,IFT52 | 46 | 0.3833126 |
| GO:BP | GO:0032647 | regulation of interferon-alpha production | 1 | TBK1 | 19 | 0.3833126 |
| GO:BP | GO:0032607 | interferon-alpha production | 1 | TBK1 | 19 | 0.3833126 |
| GO:BP | GO:0010965 | regulation of mitotic sister chromatid separation | 1 | BUB3 | 56 | 0.3836547 |
| GO:BP | GO:2000117 | negative regulation of cysteine-type endopeptidase activity | 2 | TRIAP1,NLE1 | 56 | 0.3837625 |
| GO:BP | GO:0017148 | negative regulation of translation | 4 | TRIM3,POLR2G,PML,EIF4A3 | 175 | 0.3844464 |
| GO:BP | GO:0061323 | cell proliferation involved in heart morphogenesis | 1 | MKS1 | 18 | 0.3844808 |
| GO:BP | GO:0009263 | deoxyribonucleotide biosynthetic process | 1 | DGUOK | 13 | 0.3848849 |
| GO:BP | GO:0046385 | deoxyribose phosphate biosynthetic process | 1 | DGUOK | 13 | 0.3848849 |
| GO:BP | GO:0009265 | 2’-deoxyribonucleotide biosynthetic process | 1 | DGUOK | 13 | 0.3848849 |
| GO:BP | GO:0031114 | regulation of microtubule depolymerization | 1 | NAV3 | 29 | 0.3850357 |
| GO:BP | GO:0014706 | striated muscle tissue development | 2 | LMNA,ANKRD1 | 214 | 0.3861477 |
| GO:BP | GO:0048241 | epinephrine transport | 1 | ADRA2C | 4 | 0.3863796 |
| GO:BP | GO:0035773 | insulin secretion involved in cellular response to glucose stimulus | 1 | PPP3CB | 53 | 0.3865552 |
| GO:BP | GO:2001259 | positive regulation of cation channel activity | 1 | PPP3CB | 50 | 0.3865552 |
| GO:BP | GO:0046349 | amino sugar biosynthetic process | 1 | GNPDA2 | 11 | 0.3870612 |
| GO:BP | GO:1904355 | positive regulation of telomere capping | 1 | MAP2K7 | 14 | 0.3871237 |
| GO:BP | GO:0006835 | dicarboxylic acid transport | 1 | ADORA1 | 61 | 0.3871237 |
| GO:BP | GO:0071356 | cellular response to tumor necrosis factor | 3 | ANKRD1,GSTP1,TBK1 | 159 | 0.3871237 |
| GO:BP | GO:0051924 | regulation of calcium ion transport | 2 | PSEN2,PPP3CB | 167 | 0.3871975 |
| GO:BP | GO:0006188 | IMP biosynthetic process | 1 | PAICS | 10 | 0.3873518 |
| GO:BP | GO:0060068 | vagina development | 1 | BAK1 | 8 | 0.3877224 |
| GO:BP | GO:0008090 | retrograde axonal transport | 1 | PAFAH1B1 | 20 | 0.3878667 |
| GO:BP | GO:0070344 | regulation of fat cell proliferation | 1 | PPARD | 8 | 0.3879704 |
| GO:BP | GO:2000145 | regulation of cell motility | 4 | HDAC1,LMO4,LMNA,ADORA1 | 741 | 0.3879704 |
| GO:BP | GO:0045161 | neuronal ion channel clustering | 1 | PICK1 | 8 | 0.3879704 |
| GO:BP | GO:0032966 | negative regulation of collagen biosynthetic process | 1 | PPARD | 6 | 0.3879704 |
| GO:BP | GO:0046460 | neutral lipid biosynthetic process | 1 | KAT5 | 37 | 0.3880664 |
| GO:BP | GO:0006942 | regulation of striated muscle contraction | 1 | ADORA1 | 84 | 0.3880664 |
| GO:BP | GO:0006468 | protein phosphorylation | 23 | ADORA1,AIDA,PPP3CB,STK33,BDNF,SCYL1,GSTP1,CDK4,TBK1,PRKAB1,GSKIP,WDR24,ARL2BP,TERF2IP,INCA1,HEXIM1,RPS6KB1,RPTOR,CHMP6,RIOK3,IMPACT,MOB3A,MAP2K7 | 1131 | 0.3880664 |
| GO:BP | GO:0046463 | acylglycerol biosynthetic process | 1 | KAT5 | 37 | 0.3880664 |
| GO:BP | GO:0007281 | germ cell development | 1 | PITHD1 | 194 | 0.3880664 |
| GO:BP | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome | 1 | PHF20 | 13 | 0.3880664 |
| GO:BP | GO:0072175 | epithelial tube formation | 1 | LMO4 | 124 | 0.3882194 |
| GO:BP | GO:0046883 | regulation of hormone secretion | 2 | ADORA1,PPP3CB | 170 | 0.3888545 |
| GO:BP | GO:0031529 | ruffle organization | 1 | ARFIP2 | 44 | 0.3894515 |
| GO:BP | GO:0030970 | retrograde protein transport, ER to cytosol | 1 | UBAC2 | 28 | 0.3894515 |
| GO:BP | GO:1902750 | negative regulation of cell cycle G2/M phase transition | 3 | FZR1,HUS1,RINT1 | 62 | 0.3894515 |
| GO:BP | GO:0043069 | negative regulation of programmed cell death | 4 | HDAC1,LMNA,ADORA1,PSEN2 | 685 | 0.3894515 |
| GO:BP | GO:1903513 | endoplasmic reticulum to cytosol transport | 1 | UBAC2 | 28 | 0.3894515 |
| GO:BP | GO:0060284 | regulation of cell development | 2 | PITHD1,HDAC1 | 590 | 0.3894515 |
| GO:BP | GO:0032651 | regulation of interleukin-1 beta production | 2 | GSTP1,PML | 48 | 0.3894515 |
| GO:BP | GO:0071398 | cellular response to fatty acid | 1 | CDK4 | 24 | 0.3894515 |
| GO:BP | GO:0051057 | positive regulation of small GTPase mediated signal transduction | 1 | SYNPO2L | 48 | 0.3894515 |
| GO:BP | GO:0031116 | positive regulation of microtubule polymerization | 1 | NAV3 | 31 | 0.3894515 |
| GO:BP | GO:0032611 | interleukin-1 beta production | 2 | GSTP1,PML | 48 | 0.3894515 |
| GO:BP | GO:0007095 | mitotic G2 DNA damage checkpoint signaling | 2 | FZR1,RINT1 | 35 | 0.3902699 |
| GO:BP | GO:0031398 | positive regulation of protein ubiquitination | 3 | CRY1,PEX12,FZR1 | 108 | 0.3904258 |
| GO:BP | GO:0045732 | positive regulation of protein catabolic process | 1 | RNF19B | 189 | 0.3914220 |
| GO:BP | GO:0042158 | lipoprotein biosynthetic process | 1 | PIGC | 92 | 0.3914220 |
| GO:BP | GO:0045664 | regulation of neuron differentiation | 6 | BDNF,RAC3,IMPACT,BCL11A,NEPRO,ADRA2C | 137 | 0.3915031 |
| GO:BP | GO:0051306 | mitotic sister chromatid separation | 1 | BUB3 | 59 | 0.3918888 |
| GO:BP | GO:0050728 | negative regulation of inflammatory response | 2 | ADORA1,GSTP1 | 95 | 0.3919339 |
| GO:BP | GO:1904262 | negative regulation of TORC1 signaling | 1 | WDR24 | 24 | 0.3919339 |
| GO:BP | GO:0060627 | regulation of vesicle-mediated transport | 1 | CPLANE2 | 396 | 0.3919339 |
| GO:BP | GO:0036315 | cellular response to sterol | 1 | OSBPL7 | 15 | 0.3919339 |
| GO:BP | GO:0005978 | glycogen biosynthetic process | 1 | PPP1CA | 40 | 0.3927151 |
| GO:BP | GO:0097400 | interleukin-17-mediated signaling pathway | 1 | TRAF3IP2 | 8 | 0.3927151 |
| GO:BP | GO:0009250 | glucan biosynthetic process | 1 | PPP1CA | 40 | 0.3927151 |
| GO:BP | GO:0016322 | neuron remodeling | 1 | BCL11A | 12 | 0.3927151 |
| GO:BP | GO:0071044 | histone mRNA catabolic process | 1 | TENT2 | 11 | 0.3927151 |
| GO:BP | GO:1904029 | regulation of cyclin-dependent protein kinase activity | 3 | INCA1,HEXIM1,SERTAD1 | 87 | 0.3929684 |
| GO:BP | GO:0003073 | regulation of systemic arterial blood pressure | 1 | ADORA1 | 62 | 0.3929684 |
| GO:BP | GO:0051952 | regulation of amine transport | 1 | ADORA1 | 56 | 0.3929684 |
| GO:BP | GO:0003407 | neural retina development | 3 | TTC8,RDH13,ACTL6A | 47 | 0.3930780 |
| GO:BP | GO:0099003 | vesicle-mediated transport in synapse | 2 | PPP3CB,AP2A2 | 180 | 0.3934006 |
| GO:BP | GO:0070647 | protein modification by small protein conjugation or removal | 6 | RNF19B,MED8,SDE2,HERC4,BUB3,TRIM3 | 869 | 0.3934006 |
| GO:BP | GO:0055007 | cardiac muscle cell differentiation | 1 | LMNA | 108 | 0.3936145 |
| GO:BP | GO:0010764 | negative regulation of fibroblast migration | 1 | MACIR | 10 | 0.3936145 |
| GO:BP | GO:0051784 | negative regulation of nuclear division | 1 | BUB3 | 56 | 0.3936145 |
| GO:BP | GO:0006098 | pentose-phosphate shunt | 1 | RPTOR | 19 | 0.3936145 |
| GO:BP | GO:0040019 | positive regulation of embryonic development | 1 | PAFAH1B1 | 17 | 0.3936145 |
| GO:BP | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | 1 | TRIAP1 | 29 | 0.3936145 |
| GO:BP | GO:0030010 | establishment of cell polarity | 3 | KAT5,TTC8,PAFAH1B1 | 135 | 0.3936145 |
| GO:BP | GO:0006312 | mitotic recombination | 1 | ERCC4 | 22 | 0.3936726 |
| GO:BP | GO:0045597 | positive regulation of cell differentiation | 2 | PITHD1,HDAC1 | 616 | 0.3936726 |
| GO:BP | GO:0021695 | cerebellar cortex development | 1 | CLP1 | 43 | 0.3937525 |
| GO:BP | GO:0010739 | positive regulation of protein kinase A signaling | 1 | SPATC1L | 7 | 0.3944309 |
| GO:BP | GO:0140354 | lipid import into cell | 1 | RPS6KB1 | 16 | 0.3949799 |
| GO:BP | GO:0019538 | protein metabolic process | 17 | ICMT,CPLANE2,PITHD1,LYPLA2,HDAC1,RNF19B,MED8,VPS72,MRPL9,DUSP12,TIPRL,PIGC,ADORA1,AIDA,SDE2,PSEN2,JMJD4 | 4203 | 0.3950215 |
| GO:BP | GO:0002833 | positive regulation of response to biotic stimulus | 4 | TRIM3,KAT5,RBM14,TBK1 | 217 | 0.3950215 |
| GO:BP | GO:0043101 | purine-containing compound salvage | 1 | DGUOK | 14 | 0.3950215 |
| GO:BP | GO:0043009 | chordate embryonic development | 15 | CPLANE2,LMO4,KAT5,LIG4,CLUAP1,NXN,NLE1,MKS1,EIF4A3,SLC39A3,SMG9,DHX35,IFT52,SMARCB1,MYO18B | 525 | 0.3953861 |
| GO:BP | GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1 | PPP1CA | 35 | 0.3958187 |
| GO:BP | GO:0120033 | negative regulation of plasma membrane bounded cell projection assembly | 1 | RAB3IP | 27 | 0.3958187 |
| GO:BP | GO:2000278 | regulation of DNA biosynthetic process | 3 | ANKRD1,PML,MAP2K7 | 110 | 0.3960764 |
| GO:BP | GO:0009725 | response to hormone | 2 | AGTRAP,HDAC1 | 624 | 0.3963124 |
| GO:BP | GO:0033314 | mitotic DNA replication checkpoint signaling | 1 | HUS1 | 9 | 0.3963124 |
| GO:BP | GO:0070475 | rRNA base methylation | 1 | NSUN5 | 8 | 0.3971740 |
| GO:BP | GO:0007100 | mitotic centrosome separation | 1 | NSFL1C | 13 | 0.3973962 |
| GO:BP | GO:0031952 | regulation of protein autophosphorylation | 2 | IMPACT,MOB1B | 38 | 0.3973962 |
| GO:BP | GO:0043266 | regulation of potassium ion transport | 1 | ADORA1 | 69 | 0.3983246 |
| GO:BP | GO:0071900 | regulation of protein serine/threonine kinase activity | 7 | AIDA,GSTP1,INCA1,HEXIM1,RPTOR,MAP2K7,SERTAD1 | 274 | 0.3990738 |
| GO:BP | GO:0043984 | histone H4-K16 acetylation | 1 | PHF20 | 14 | 0.4007655 |
| GO:BP | GO:0023057 | negative regulation of signaling | 21 | HDAC1,LMNA,ADORA1,AIDA,HERC4,PPP3CB,BDNF,BRMS1,GSTP1,CRY1,TRIAP1,UBAC2,ING1,WDR24,NXN,PAFAH1B1,NLE1,RPS6KB1,CHMP6,RIOK3,PIAS4 | 1089 | 0.4007655 |
| GO:BP | GO:0002218 | activation of innate immune response | 5 | TRIM3,RBM14,TBK1,HEXIM1,RIOK3 | 166 | 0.4007655 |
| GO:BP | GO:0070252 | actin-mediated cell contraction | 1 | ADORA1 | 90 | 0.4007655 |
| GO:BP | GO:0060415 | muscle tissue morphogenesis | 1 | ANKRD1 | 61 | 0.4007655 |
| GO:BP | GO:0036503 | ERAD pathway | 2 | AQP11,UBAC2 | 104 | 0.4007655 |
| GO:BP | GO:0015833 | peptide transport | 2 | ADORA1,PPP3CB | 181 | 0.4007655 |
| GO:BP | GO:0006518 | peptide metabolic process | 15 | MRPL9,PSEN2,JMJD4,TRIM3,POLR2G,PPP1CA,BRF1,TRIP4,PML,EFL1,CASC3,RPS6KB1,EIF4A3,IMPACT,FARSA | 781 | 0.4007655 |
| GO:BP | GO:1903573 | negative regulation of response to endoplasmic reticulum stress | 1 | AQP11 | 41 | 0.4007655 |
| GO:BP | GO:0043122 | regulation of canonical NF-kappaB signal transduction | 5 | HDAC1,GSTP1,TBK1,TERF2IP,RIOK3 | 206 | 0.4007655 |
| GO:BP | GO:0006054 | N-acetylneuraminate metabolic process | 1 | GNPDA2 | 12 | 0.4007655 |
| GO:BP | GO:0035148 | tube formation | 1 | LMO4 | 133 | 0.4010324 |
| GO:BP | GO:0016024 | CDP-diacylglycerol biosynthetic process | 1 | TAMM41 | 12 | 0.4018671 |
| GO:BP | GO:0043244 | regulation of protein-containing complex disassembly | 2 | JMJD4,NAV3 | 109 | 0.4018671 |
| GO:BP | GO:0050769 | positive regulation of neurogenesis | 1 | HDAC1 | 189 | 0.4018671 |
| GO:BP | GO:0060079 | excitatory postsynaptic potential | 1 | ADORA1 | 69 | 0.4018671 |
| GO:BP | GO:0035914 | skeletal muscle cell differentiation | 1 | ANKRD1 | 52 | 0.4018671 |
| GO:BP | GO:0090559 | regulation of membrane permeability | 1 | BLOC1S2 | 62 | 0.4018671 |
| GO:BP | GO:0032413 | negative regulation of ion transmembrane transporter activity | 1 | PPP3CB | 52 | 0.4018671 |
| GO:BP | GO:0045747 | positive regulation of Notch signaling pathway | 2 | SLC35C2,NEPRO | 37 | 0.4018671 |
| GO:BP | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport | 1 | RINT1 | 9 | 0.4018671 |
| GO:BP | GO:0009056 | catabolic process | 36 | PITHD1,LYPLA2,STX12,RNF19B,LIX1L,ADORA1,HERC4,TRIM3,ARFIP2,VPS37C,POLR2G,KAT5,PPP1CA,AQP11,PAFAH1B2,EI24,CDK4,TBK1,CRY1,UBAC2,ABHD13,TRIP4,PML,WDR24,ERCC4,CES2,CHMP1A,PAFAH1B1,PEX12,CASC3,OSBPL7,SPOP,GDPD1,EIF4A3,RPTOR,CHMP6 | 2106 | 0.4018671 |
| GO:BP | GO:0046341 | CDP-diacylglycerol metabolic process | 1 | TAMM41 | 12 | 0.4018671 |
| GO:BP | GO:0045859 | regulation of protein kinase activity | 11 | ADORA1,AIDA,GSTP1,GSKIP,WDR24,INCA1,HEXIM1,RPTOR,CHMP6,MAP2K7,SERTAD1 | 473 | 0.4018671 |
| GO:BP | GO:0043409 | negative regulation of MAPK cascade | 2 | AIDA,GSTP1 | 145 | 0.4018671 |
| GO:BP | GO:0071260 | cellular response to mechanical stimulus | 1 | ANKRD1 | 56 | 0.4018671 |
| GO:BP | GO:0010713 | negative regulation of collagen metabolic process | 1 | PPARD | 7 | 0.4019494 |
| GO:BP | GO:0048706 | embryonic skeletal system development | 3 | MKS1,EIF4A3,SLC39A3 | 77 | 0.4019494 |
| GO:BP | GO:0007084 | mitotic nuclear membrane reassembly | 1 | REEP4 | 10 | 0.4019494 |
| GO:BP | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient | 1 | BAK1 | 7 | 0.4019494 |
| GO:BP | GO:0009126 | purine nucleoside monophosphate metabolic process | 2 | DGUOK,PAICS | 38 | 0.4019494 |
| GO:BP | GO:0101024 | mitotic nuclear membrane organization | 1 | REEP4 | 10 | 0.4019494 |
| GO:BP | GO:0032481 | positive regulation of type I interferon production | 2 | TBK1,RIOK3 | 50 | 0.4019494 |
| GO:BP | GO:0052548 | regulation of endopeptidase activity | 5 | HDAC1,TRIAP1,DIABLO,PML,NLE1 | 220 | 0.4019494 |
| GO:BP | GO:0010165 | response to X-ray | 1 | LIG4 | 28 | 0.4019494 |
| GO:BP | GO:0048643 | positive regulation of skeletal muscle tissue development | 1 | RPS6KB1 | 14 | 0.4026529 |
| GO:BP | GO:0045010 | actin nucleation | 1 | ARFIP2 | 49 | 0.4030829 |
| GO:BP | GO:0030252 | growth hormone secretion | 1 | RAB1A | 12 | 0.4032943 |
| GO:BP | GO:0090110 | COPII-coated vesicle cargo loading | 1 | RAB1A | 15 | 0.4032943 |
| GO:BP | GO:0097154 | GABAergic neuron differentiation | 1 | RAC3 | 7 | 0.4033895 |
| GO:BP | GO:0099188 | postsynaptic cytoskeleton organization | 1 | RAC3 | 17 | 0.4033895 |
| GO:BP | GO:0042574 | retinal metabolic process | 1 | RDH13 | 10 | 0.4033895 |
| GO:BP | GO:0015850 | organic hydroxy compound transport | 1 | STX12 | 181 | 0.4033895 |
| GO:BP | GO:0016331 | morphogenesis of embryonic epithelium | 1 | LMO4 | 130 | 0.4041870 |
| GO:BP | GO:0048863 | stem cell differentiation | 1 | HDAC1 | 196 | 0.4046350 |
| GO:BP | GO:0009913 | epidermal cell differentiation | 1 | HDAC1 | 116 | 0.4046350 |
| GO:BP | GO:0040012 | regulation of locomotion | 4 | HDAC1,LMO4,LMNA,ADORA1 | 762 | 0.4048947 |
| GO:BP | GO:0034260 | negative regulation of GTPase activity | 1 | TTC8 | 25 | 0.4050095 |
| GO:BP | GO:0000122 | negative regulation of transcription by RNA polymerase II | 18 | HDAC1,LMO4,VPS72,SUV39H2,KAT5,BRMS1,CRY1,KMT5A,ING1,ZFP90,HEXIM1,IMPACT,MIER2,PIAS4,ZNF440,ZNF587B,MTA3,BCL11A | 744 | 0.4052248 |
| GO:BP | GO:0060291 | long-term synaptic potentiation | 1 | ADORA1 | 66 | 0.4057551 |
| GO:BP | GO:0051568 | histone H3-K4 methylation | 2 | PHF20,NELFA | 41 | 0.4057551 |
| GO:BP | GO:0009151 | purine deoxyribonucleotide metabolic process | 1 | DGUOK | 12 | 0.4058391 |
| GO:BP | GO:0009404 | toxin metabolic process | 1 | N6AMT1 | 5 | 0.4062283 |
| GO:BP | GO:1902902 | negative regulation of autophagosome assembly | 1 | TMEM39A | 12 | 0.4062692 |
| GO:BP | GO:0090092 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 1 | HDAC1 | 211 | 0.4073063 |
| GO:BP | GO:0048667 | cell morphogenesis involved in neuron differentiation | 4 | LYPLA2,LMO4,PPP3CB,BDNF | 450 | 0.4079011 |
| GO:BP | GO:0045833 | negative regulation of lipid metabolic process | 1 | ADORA1 | 74 | 0.4080166 |
| GO:BP | GO:0007264 | small GTPase mediated signal transduction | 1 | ARHGEF10L | 414 | 0.4082021 |
| GO:BP | GO:0050708 | regulation of protein secretion | 2 | PPP3CB,ANKRD1 | 185 | 0.4082021 |
| GO:BP | GO:0061484 | hematopoietic stem cell homeostasis | 1 | NLE1 | 20 | 0.4082642 |
| GO:BP | GO:0001825 | blastocyst formation | 2 | NLE1,ACTL6A | 37 | 0.4082642 |
| GO:BP | GO:0010001 | glial cell differentiation | 1 | HDAC1 | 181 | 0.4088759 |
| GO:BP | GO:0051299 | centrosome separation | 1 | NSFL1C | 14 | 0.4095167 |
| GO:BP | GO:0031112 | positive regulation of microtubule polymerization or depolymerization | 1 | NAV3 | 35 | 0.4096816 |
| GO:BP | GO:1903365 | regulation of fear response | 1 | PRKAR1B | 8 | 0.4099447 |
| GO:BP | GO:1901797 | negative regulation of signal transduction by p53 class mediator | 1 | TRIAP1 | 31 | 0.4099447 |
| GO:BP | GO:0051148 | negative regulation of muscle cell differentiation | 1 | BDNF | 51 | 0.4099447 |
| GO:BP | GO:1902253 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator | 1 | TRIAP1 | 32 | 0.4099447 |
| GO:BP | GO:0032543 | mitochondrial translation | 1 | MRPL9 | 130 | 0.4099500 |
| GO:BP | GO:1903232 | melanosome assembly | 1 | AP1M1 | 19 | 0.4099922 |
| GO:BP | GO:0001932 | regulation of protein phosphorylation | 16 | ADORA1,AIDA,BDNF,GSTP1,TBK1,GSKIP,WDR24,ARL2BP,TERF2IP,INCA1,HEXIM1,RPTOR,CHMP6,IMPACT,MOB3A,MAP2K7 | 758 | 0.4099922 |
| GO:BP | GO:0006360 | transcription by RNA polymerase I | 3 | SMARCB1,POLR1C,POLR1F | 70 | 0.4099922 |
| GO:BP | GO:0098976 | excitatory chemical synaptic transmission | 1 | PDLIM4 | 8 | 0.4099922 |
| GO:BP | GO:1902742 | apoptotic process involved in development | 2 | PML,BAK1 | 30 | 0.4099922 |
| GO:BP | GO:0016571 | histone methylation | 1 | SUV39H2 | 80 | 0.4105727 |
| GO:BP | GO:0048639 | positive regulation of developmental growth | 4 | BDNF,PAFAH1B1,RPS6KB1,BCL11A | 124 | 0.4105727 |
| GO:BP | GO:0051385 | response to mineralocorticoid | 1 | RAN | 20 | 0.4107500 |
| GO:BP | GO:0015837 | amine transport | 1 | ADORA1 | 59 | 0.4107500 |
| GO:BP | GO:0042359 | vitamin D metabolic process | 1 | PIAS4 | 9 | 0.4108903 |
| GO:BP | GO:0032879 | regulation of localization | 2 | PLEKHM2,CPLANE2 | 1568 | 0.4110883 |
| GO:BP | GO:0062208 | positive regulation of pattern recognition receptor signaling pathway | 1 | TRIM3 | 43 | 0.4110883 |
| GO:BP | GO:0032872 | regulation of stress-activated MAPK cascade | 4 | AIDA,GSTP1,PAFAH1B1,MAP2K7 | 153 | 0.4112116 |
| GO:BP | GO:0061326 | renal tubule development | 2 | AQP11,TTC8 | 78 | 0.4112811 |
| GO:BP | GO:0071216 | cellular response to biotic stimulus | 3 | ANKRD1,GSTP1,CDK4 | 141 | 0.4112811 |
| GO:BP | GO:0015748 | organophosphate ester transport | 3 | GLTP,TRIAP1,SLC35B1 | 105 | 0.4116161 |
| GO:BP | GO:0035249 | synaptic transmission, glutamatergic | 1 | ADORA1 | 65 | 0.4125631 |
| GO:BP | GO:0014061 | regulation of norepinephrine secretion | 1 | ADRA2C | 5 | 0.4129937 |
| GO:BP | GO:0048243 | norepinephrine secretion | 1 | ADRA2C | 5 | 0.4129937 |
| GO:BP | GO:0033604 | negative regulation of catecholamine secretion | 1 | ADRA2C | 6 | 0.4129937 |
| GO:BP | GO:0009156 | ribonucleoside monophosphate biosynthetic process | 2 | PAICS,UPRT | 31 | 0.4139510 |
| GO:BP | GO:0031668 | cellular response to extracellular stimulus | 8 | KAT5,PRKAB1,WDR24,RPTOR,IMPACT,PICK1,CPEB4,PPARD | 223 | 0.4139510 |
| GO:BP | GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 5 | HDAC1,BRMS1,RBM14,ING1,PML | 297 | 0.4141062 |
| GO:BP | GO:0008283 | cell population proliferation | 1 | WRAP73 | 2339 | 0.4141062 |
| GO:BP | GO:0018904 | ether metabolic process | 1 | PAFAH1B1 | 21 | 0.4141062 |
| GO:BP | GO:0009642 | response to light intensity | 1 | RDH13 | 10 | 0.4141062 |
| GO:BP | GO:0050848 | regulation of calcium-mediated signaling | 1 | PPP3CB | 51 | 0.4141062 |
| GO:BP | GO:0099565 | chemical synaptic transmission, postsynaptic | 1 | ADORA1 | 74 | 0.4141062 |
| GO:BP | GO:0010459 | negative regulation of heart rate | 1 | SRI | 7 | 0.4141062 |
| GO:BP | GO:0018202 | peptidyl-histidine modification | 1 | DPH7 | 10 | 0.4141062 |
| GO:BP | GO:0001675 | acrosome assembly | 1 | PAFAH1B1 | 16 | 0.4141062 |
| GO:BP | GO:0060117 | auditory receptor cell development | 1 | PAFAH1B1 | 14 | 0.4141062 |
| GO:BP | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity | 1 | SRI | 10 | 0.4141062 |
| GO:BP | GO:0006167 | AMP biosynthetic process | 1 | PAICS | 13 | 0.4141062 |
| GO:BP | GO:0000086 | G2/M transition of mitotic cell cycle | 5 | CDK4,FZR1,MTA3,HUS1,RINT1 | 130 | 0.4150820 |
| GO:BP | GO:0043604 | amide biosynthetic process | 15 | MRPL9,JMJD4,TRIM3,POLR2G,PPP1CA,BRF1,TRIP4,PML,EFL1,CASC3,RPS6KB1,EIF4A3,IMPACT,CERS4,FARSA | 786 | 0.4150820 |
| GO:BP | GO:0048644 | muscle organ morphogenesis | 1 | ANKRD1 | 64 | 0.4154123 |
| GO:BP | GO:0007611 | learning or memory | 5 | PPP3CB,BDNF,PAFAH1B1,RPS6KB1,EIF4A3 | 200 | 0.4171960 |
| GO:BP | GO:1904263 | positive regulation of TORC1 signaling | 1 | WDR24 | 29 | 0.4171960 |
| GO:BP | GO:0060219 | camera-type eye photoreceptor cell differentiation | 1 | TTC8 | 18 | 0.4174422 |
| GO:BP | GO:0048563 | post-embryonic animal organ morphogenesis | 1 | BAK1 | 8 | 0.4177697 |
| GO:BP | GO:0003205 | cardiac chamber development | 1 | LMO4 | 150 | 0.4182745 |
| GO:BP | GO:0014842 | regulation of skeletal muscle satellite cell proliferation | 1 | PPARD | 8 | 0.4183999 |
| GO:BP | GO:2000288 | positive regulation of myoblast proliferation | 1 | PPARD | 9 | 0.4183999 |
| GO:BP | GO:0051965 | positive regulation of synapse assembly | 1 | BDNF | 43 | 0.4188810 |
| GO:BP | GO:0033135 | regulation of peptidyl-serine phosphorylation | 3 | BDNF,TBK1,RPTOR | 97 | 0.4189249 |
| GO:BP | GO:0006740 | NADPH regeneration | 1 | RPTOR | 22 | 0.4189249 |
| GO:BP | GO:0045821 | positive regulation of glycolytic process | 1 | RPTOR | 16 | 0.4189249 |
| GO:BP | GO:1903706 | regulation of hemopoiesis | 1 | PITHD1 | 265 | 0.4189249 |
| GO:BP | GO:0035023 | regulation of Rho protein signal transduction | 1 | SYNPO2L | 65 | 0.4189249 |
| GO:BP | GO:0098869 | cellular oxidant detoxification | 2 | GSTP1,NXN | 64 | 0.4191677 |
| GO:BP | GO:0061387 | regulation of extent of cell growth | 3 | BDNF,PAFAH1B1,BCL11A | 96 | 0.4191949 |
| GO:BP | GO:0032410 | negative regulation of transporter activity | 1 | PPP3CB | 59 | 0.4191949 |
| GO:BP | GO:0033003 | regulation of mast cell activation | 1 | C12orf4 | 24 | 0.4196173 |
| GO:BP | GO:0070534 | protein K63-linked ubiquitination | 3 | TRIM3,TRAF3IP2,UBE2V2 | 62 | 0.4204138 |
| GO:BP | GO:0070365 | hepatocyte differentiation | 1 | SMARCB1 | 12 | 0.4211635 |
| GO:BP | GO:0033630 | positive regulation of cell adhesion mediated by integrin | 1 | RAC3 | 14 | 0.4211635 |
| GO:BP | GO:0001960 | negative regulation of cytokine-mediated signaling pathway | 2 | GSTP1,PIAS4 | 52 | 0.4211635 |
| GO:BP | GO:0045913 | positive regulation of carbohydrate metabolic process | 2 | CRY1,RPTOR | 61 | 0.4211635 |
| GO:BP | GO:0090385 | phagosome-lysosome fusion | 1 | RAB7A | 12 | 0.4211635 |
| GO:BP | GO:1901836 | regulation of transcription of nucleolar large rRNA by RNA polymerase I | 1 | SMARCB1 | 15 | 0.4211635 |
| GO:BP | GO:0009749 | response to glucose | 2 | PPP3CB,KAT5 | 138 | 0.4211635 |
| GO:BP | GO:0070302 | regulation of stress-activated protein kinase signaling cascade | 4 | AIDA,GSTP1,PAFAH1B1,MAP2K7 | 157 | 0.4213624 |
| GO:BP | GO:0070723 | response to cholesterol | 1 | OSBPL7 | 17 | 0.4216257 |
| GO:BP | GO:0097049 | motor neuron apoptotic process | 1 | MAP2K7 | 18 | 0.4222503 |
| GO:BP | GO:0060042 | retina morphogenesis in camera-type eye | 2 | TTC8,RDH13 | 40 | 0.4225140 |
| GO:BP | GO:1905818 | regulation of chromosome separation | 1 | BUB3 | 69 | 0.4225140 |
| GO:BP | GO:0000027 | ribosomal large subunit assembly | 1 | NLE1 | 25 | 0.4228473 |
| GO:BP | GO:0070131 | positive regulation of mitochondrial translation | 1 | METTL8 | 17 | 0.4229556 |
| GO:BP | GO:0043982 | histone H4-K8 acetylation | 1 | PHF20 | 16 | 0.4229556 |
| GO:BP | GO:0043981 | histone H4-K5 acetylation | 1 | PHF20 | 16 | 0.4229556 |
| GO:BP | GO:0043405 | regulation of MAP kinase activity | 2 | AIDA,GSTP1 | 141 | 0.4232114 |
| GO:BP | GO:0006749 | glutathione metabolic process | 1 | GSTP1 | 41 | 0.4232114 |
| GO:BP | GO:0031111 | negative regulation of microtubule polymerization or depolymerization | 1 | NAV3 | 36 | 0.4235878 |
| GO:BP | GO:0061311 | cell surface receptor signaling pathway involved in heart development | 1 | MKS1 | 18 | 0.4235878 |
| GO:BP | GO:0009451 | RNA modification | 1 | NSUN4 | 167 | 0.4242402 |
| GO:BP | GO:0010604 | positive regulation of macromolecule metabolic process | 49 | PITHD1,HDAC1,RNF19B,MED8,LMO4,VPS72,LMNA,ADORA1,JMJD4,ECD,PPP3CB,ANKRD1,BLOC1S2,BDNF,POLR2G,KAT5,BRMS1,RBM14,ARAP1,MED17,ANKRD49,TBK1,CRY1,PRKAB1,TRIAP1,DIABLO,GTF2F2,ING1,BRF1,TRIP4,PML,WDR24,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,PEX12,OSBPL7,SRSF1,RPS6KB1,EIF4A3,RPTOR,RIOK3,IMPACT,MOB3A,FZR1,PIAS4,MAP2K7 | 2607 | 0.4243577 |
| GO:BP | GO:0002753 | cytosolic pattern recognition receptor signaling pathway | 2 | TRIM3,TBK1 | 98 | 0.4247088 |
| GO:BP | GO:1901989 | positive regulation of cell cycle phase transition | 3 | CDK4,RPTOR,MTA3 | 101 | 0.4247088 |
| GO:BP | GO:0039532 | negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway | 2 | RIOK3,ZDHHC12 | 27 | 0.4247958 |
| GO:BP | GO:0051336 | regulation of hydrolase activity | 2 | ASAP3,HDAC1 | 680 | 0.4253506 |
| GO:BP | GO:0060338 | regulation of type I interferon-mediated signaling pathway | 1 | TBK1 | 35 | 0.4253506 |
| GO:BP | GO:0051253 | negative regulation of RNA metabolic process | 9 | PEX14,HDAC1,LMO4,VPS72,SUV39H2,ANKRD1,SPINDOC,KAT5,BRMS1 | 1111 | 0.4260777 |
| GO:BP | GO:0048729 | tissue morphogenesis | 1 | CPLANE2 | 501 | 0.4261752 |
| GO:BP | GO:0032024 | positive regulation of insulin secretion | 1 | PPP3CB | 59 | 0.4261752 |
| GO:BP | GO:1901799 | negative regulation of proteasomal protein catabolic process | 1 | AQP11 | 47 | 0.4263743 |
| GO:BP | GO:0042327 | positive regulation of phosphorylation | 3 | LMO4,DUSP12,ADORA1 | 511 | 0.4263743 |
| GO:BP | GO:0030099 | myeloid cell differentiation | 1 | PITHD1 | 304 | 0.4263743 |
| GO:BP | GO:0120255 | olefinic compound biosynthetic process | 1 | HSD17B1 | 18 | 0.4263743 |
| GO:BP | GO:1900544 | positive regulation of purine nucleotide metabolic process | 1 | RPTOR | 16 | 0.4270753 |
| GO:BP | GO:0045981 | positive regulation of nucleotide metabolic process | 1 | RPTOR | 16 | 0.4270753 |
| GO:BP | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint | 1 | MAD1L1 | 12 | 0.4270753 |
| GO:BP | GO:0090232 | positive regulation of spindle checkpoint | 1 | MAD1L1 | 12 | 0.4270753 |
| GO:BP | GO:0044060 | regulation of endocrine process | 1 | CRY1 | 24 | 0.4271228 |
| GO:BP | GO:0043173 | nucleotide salvage | 1 | DGUOK | 15 | 0.4271228 |
| GO:BP | GO:0006047 | UDP-N-acetylglucosamine metabolic process | 1 | GNPDA2 | 13 | 0.4271228 |
| GO:BP | GO:0034067 | protein localization to Golgi apparatus | 1 | COG7 | 27 | 0.4271228 |
| GO:BP | GO:0009792 | embryo development ending in birth or egg hatching | 15 | CPLANE2,LMO4,KAT5,LIG4,CLUAP1,NXN,NLE1,MKS1,EIF4A3,SLC39A3,SMG9,DHX35,IFT52,SMARCB1,MYO18B | 542 | 0.4277380 |
| GO:BP | GO:0006177 | GMP biosynthetic process | 1 | PAICS | 13 | 0.4277380 |
| GO:BP | GO:2001135 | regulation of endocytic recycling | 1 | EIPR1 | 17 | 0.4281698 |
| GO:BP | GO:0009746 | response to hexose | 2 | PPP3CB,KAT5 | 139 | 0.4281698 |
| GO:BP | GO:0022030 | telencephalon glial cell migration | 1 | PAFAH1B1 | 22 | 0.4281698 |
| GO:BP | GO:0021801 | cerebral cortex radial glia-guided migration | 1 | PAFAH1B1 | 22 | 0.4281698 |
| GO:BP | GO:0001776 | leukocyte homeostasis | 4 | PPP3CB,SLC39A3,BAK1,TRAF3IP2 | 73 | 0.4288994 |
| GO:BP | GO:0044281 | small molecule metabolic process | 1 | ICMT | 1387 | 0.4288994 |
| GO:BP | GO:0021537 | telencephalon development | 1 | HDAC1 | 208 | 0.4290882 |
| GO:BP | GO:0014733 | regulation of skeletal muscle adaptation | 1 | GTF2IRD1 | 11 | 0.4298810 |
| GO:BP | GO:0060603 | mammary gland duct morphogenesis | 1 | PML | 28 | 0.4313907 |
| GO:BP | GO:0030032 | lamellipodium assembly | 1 | ARFIP2 | 59 | 0.4314140 |
| GO:BP | GO:0051238 | sequestering of metal ion | 1 | SRI | 7 | 0.4314140 |
| GO:BP | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction | 1 | SRI | 12 | 0.4314140 |
| GO:BP | GO:0035050 | embryonic heart tube development | 3 | CLUAP1,IFT52,BBS7 | 69 | 0.4316614 |
| GO:BP | GO:0034249 | negative regulation of amide metabolic process | 2 | TRIM3,POLR2G | 196 | 0.4326453 |
| GO:BP | GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 1 | BAK1 | 12 | 0.4326453 |
| GO:BP | GO:0006631 | fatty acid metabolic process | 1 | LYPLA2 | 277 | 0.4326453 |
| GO:BP | GO:0001818 | negative regulation of cytokine production | 4 | KAT5,GSTP1,NAV3,PML | 171 | 0.4326453 |
| GO:BP | GO:1904063 | negative regulation of cation transmembrane transport | 1 | PPP3CB | 64 | 0.4326453 |
| GO:BP | GO:0010225 | response to UV-C | 1 | BAK1 | 13 | 0.4326453 |
| GO:BP | GO:0034394 | protein localization to cell surface | 1 | BDNF | 60 | 0.4330131 |
| GO:BP | GO:0048598 | embryonic morphogenesis | 2 | HDAC1,LMO4 | 438 | 0.4334312 |
| GO:BP | GO:0009968 | negative regulation of signal transduction | 19 | HDAC1,LMNA,AIDA,HERC4,BDNF,BRMS1,GSTP1,CRY1,TRIAP1,UBAC2,ING1,WDR24,NXN,PAFAH1B1,NLE1,RPS6KB1,CHMP6,RIOK3,PIAS4 | 1016 | 0.4335233 |
| GO:BP | GO:0006222 | UMP biosynthetic process | 1 | UPRT | 9 | 0.4339887 |
| GO:BP | GO:0090596 | sensory organ morphogenesis | 1 | HDAC1 | 179 | 0.4349546 |
| GO:BP | GO:1903543 | positive regulation of exosomal secretion | 1 | RAB7A | 13 | 0.4349546 |
| GO:BP | GO:0010587 | miRNA catabolic process | 1 | TENT2 | 12 | 0.4358166 |
| GO:BP | GO:1901863 | positive regulation of muscle tissue development | 1 | RPS6KB1 | 18 | 0.4358166 |
| GO:BP | GO:0051962 | positive regulation of nervous system development | 1 | HDAC1 | 221 | 0.4358166 |
| GO:BP | GO:0006778 | porphyrin-containing compound metabolic process | 2 | RSAD1,SRRD | 43 | 0.4358490 |
| GO:BP | GO:0003014 | renal system process | 1 | ADORA1 | 76 | 0.4358490 |
| GO:BP | GO:1903532 | positive regulation of secretion by cell | 2 | PPP3CB,ANKRD1 | 198 | 0.4364699 |
| GO:BP | GO:0009790 | embryo development | 3 | CPLANE2,HDAC1,LMO4 | 859 | 0.4370599 |
| GO:BP | GO:0009410 | response to xenobiotic stimulus | 7 | ANKRD1,GSTP1,CDK4,CES2,RPS6KB1,SRP68,RPTOR | 275 | 0.4370599 |
| GO:BP | GO:0001910 | regulation of leukocyte mediated cytotoxicity | 1 | PPP3CB | 36 | 0.4378918 |
| GO:BP | GO:0090317 | negative regulation of intracellular protein transport | 2 | UBAC2,RAB23 | 37 | 0.4378918 |
| GO:BP | GO:0010907 | positive regulation of glucose metabolic process | 1 | CRY1 | 37 | 0.4378918 |
| GO:BP | GO:0048384 | retinoic acid receptor signaling pathway | 1 | PML | 27 | 0.4378918 |
| GO:BP | GO:0048588 | developmental cell growth | 2 | PPP3CB,BDNF | 194 | 0.4378918 |
| GO:BP | GO:0001763 | morphogenesis of a branching structure | 5 | PPP1CA,PML,MKS1,BCL11A,GZF1 | 155 | 0.4380333 |
| GO:BP | GO:0009966 | regulation of signal transduction | 42 | CPLANE2,ARHGEF10L,HDAC1,LMNA,ADORA1,AIDA,HERC4,PPP3CB,SYNPO2L,ANKRD1,TRIM3,BDNF,BRMS1,RAD9A,PPP1CA,GSTP1,ARAP1,CDK4,TBK1,CRY1,TRIAP1,KMT5A,UBAC2,ING1,RALGAPA1,GSKIP,PML,WDR24,TERF2IP,NXN,PAFAH1B1,INCA1,NLE1,HEXIM1,MKS1,RPS6KB1,EIF4A3,RPTOR,CHMP6,RIOK3,PIAS4,MAP2K7 | 2270 | 0.4382701 |
| GO:BP | GO:0060761 | negative regulation of response to cytokine stimulus | 2 | GSTP1,PIAS4 | 56 | 0.4382701 |
| GO:BP | GO:0007249 | canonical NF-kappaB signal transduction | 1 | HDAC1 | 232 | 0.4397041 |
| GO:BP | GO:0071359 | cellular response to dsRNA | 1 | RIOK3 | 18 | 0.4397041 |
| GO:BP | GO:0032652 | regulation of interleukin-1 production | 2 | GSTP1,PML | 56 | 0.4397041 |
| GO:BP | GO:0032612 | interleukin-1 production | 2 | GSTP1,PML | 56 | 0.4397041 |
| GO:BP | GO:1901984 | negative regulation of protein acetylation | 1 | CTBP1 | 13 | 0.4397041 |
| GO:BP | GO:0022412 | cellular process involved in reproduction in multicellular organism | 1 | PITHD1 | 255 | 0.4397041 |
| GO:BP | GO:2000050 | regulation of non-canonical Wnt signaling pathway | 1 | MKS1 | 23 | 0.4397041 |
| GO:BP | GO:0036065 | fucosylation | 1 | SLC35C2 | 10 | 0.4398951 |
| GO:BP | GO:0002327 | immature B cell differentiation | 1 | TRAF3IP2 | 11 | 0.4398951 |
| GO:BP | GO:0035051 | cardiocyte differentiation | 1 | LMNA | 134 | 0.4398951 |
| GO:BP | GO:0071466 | cellular response to xenobiotic stimulus | 2 | ANKRD1,GSTP1 | 108 | 0.4408352 |
| GO:BP | GO:0031329 | regulation of cellular catabolic process | 10 | POLR2G,KAT5,PAFAH1B2,TBK1,WDR24,ERCC4,CASC3,OSBPL7,EIF4A3,RPTOR | 562 | 0.4408352 |
| GO:BP | GO:0006607 | NLS-bearing protein import into nucleus | 1 | RANBP2 | 18 | 0.4408352 |
| GO:BP | GO:0046348 | amino sugar catabolic process | 1 | GNPDA2 | 10 | 0.4408352 |
| GO:BP | GO:0090162 | establishment of epithelial cell polarity | 1 | TTC8 | 30 | 0.4408352 |
| GO:BP | GO:0048754 | branching morphogenesis of an epithelial tube | 3 | PPP1CA,PML,MKS1 | 121 | 0.4408352 |
| GO:BP | GO:0051452 | intracellular pH reduction | 1 | AQP11 | 46 | 0.4408352 |
| GO:BP | GO:0034284 | response to monosaccharide | 2 | PPP3CB,KAT5 | 143 | 0.4408352 |
| GO:BP | GO:0043300 | regulation of leukocyte degranulation | 1 | C12orf4 | 26 | 0.4408352 |
| GO:BP | GO:0042594 | response to starvation | 4 | KAT5,WDR24,RPTOR,IMPACT | 176 | 0.4408352 |
| GO:BP | GO:0042593 | glucose homeostasis | 3 | PPP3CB,KAT5,CRY1 | 172 | 0.4408352 |
| GO:BP | GO:0140053 | mitochondrial gene expression | 4 | MRPL9,TEFM,TRMT61B,METTL8 | 162 | 0.4408352 |
| GO:BP | GO:0071230 | cellular response to amino acid stimulus | 3 | RPTOR,BCL11A,CPEB4 | 66 | 0.4423828 |
| GO:BP | GO:0051051 | negative regulation of transport | 5 | ADORA1,PPP3CB,ANKRD13D,CRY1,UBAC2 | 317 | 0.4423828 |
| GO:BP | GO:0071549 | cellular response to dexamethasone stimulus | 1 | RPS6KB1 | 23 | 0.4423828 |
| GO:BP | GO:0021952 | central nervous system projection neuron axonogenesis | 1 | PAFAH1B1 | 24 | 0.4423828 |
| GO:BP | GO:0016477 | cell migration | 5 | ASAP3,HDAC1,LMO4,LMNA,ADORA1 | 1064 | 0.4423828 |
| GO:BP | GO:0048641 | regulation of skeletal muscle tissue development | 1 | RPS6KB1 | 19 | 0.4423828 |
| GO:BP | GO:0003012 | muscle system process | 2 | LMNA,ADORA1 | 334 | 0.4423828 |
| GO:BP | GO:0033500 | carbohydrate homeostasis | 3 | PPP3CB,KAT5,CRY1 | 173 | 0.4423828 |
| GO:BP | GO:0043254 | regulation of protein-containing complex assembly | 2 | LMO4,AIDA | 340 | 0.4424144 |
| GO:BP | GO:0032368 | regulation of lipid transport | 2 | CRY1,TRIAP1 | 91 | 0.4424144 |
| GO:BP | GO:0030048 | actin filament-based movement | 1 | ADORA1 | 111 | 0.4425202 |
| GO:BP | GO:0010821 | regulation of mitochondrion organization | 1 | LMNA | 133 | 0.4429324 |
| GO:BP | GO:0006810 | transport | 2 | ICMT,PEX14 | 3295 | 0.4431982 |
| GO:BP | GO:0060623 | regulation of chromosome condensation | 1 | SMC2 | 12 | 0.4444774 |
| GO:BP | GO:2000773 | negative regulation of cellular senescence | 1 | FZR1 | 19 | 0.4444774 |
| GO:BP | GO:0010243 | response to organonitrogen compound | 1 | AGTRAP | 765 | 0.4444774 |
| GO:BP | GO:0048812 | neuron projection morphogenesis | 2 | LYPLA2,LMO4 | 499 | 0.4444774 |
| GO:BP | GO:0006970 | response to osmotic stress | 2 | RPTOR,MAP2K7 | 64 | 0.4450705 |
| GO:BP | GO:1901019 | regulation of calcium ion transmembrane transporter activity | 1 | PPP3CB | 70 | 0.4450705 |
| GO:BP | GO:0002709 | regulation of T cell mediated immunity | 1 | PPP3CB | 45 | 0.4450705 |
| GO:BP | GO:0021772 | olfactory bulb development | 1 | TTC8 | 20 | 0.4458843 |
| GO:BP | GO:1900103 | positive regulation of endoplasmic reticulum unfolded protein response | 1 | BAK1 | 13 | 0.4469963 |
| GO:BP | GO:0010524 | positive regulation of calcium ion transport into cytosol | 1 | BAK1 | 7 | 0.4469963 |
| GO:BP | GO:1901841 | regulation of high voltage-gated calcium channel activity | 1 | SRI | 12 | 0.4469963 |
| GO:BP | GO:0051280 | negative regulation of release of sequestered calcium ion into cytosol | 1 | SRI | 11 | 0.4469963 |
| GO:BP | GO:0099638 | endosome to plasma membrane protein transport | 1 | RAB7A | 15 | 0.4469963 |
| GO:BP | GO:0016043 | cellular component organization | 6 | WRAP73,PEX14,PLEKHM2,CPLANE2,ARHGEF10L,ASAP3 | 5116 | 0.4469963 |
| GO:BP | GO:0032720 | negative regulation of tumor necrosis factor production | 1 | GSTP1 | 32 | 0.4473237 |
| GO:BP | GO:0046879 | hormone secretion | 2 | ADORA1,PPP3CB | 211 | 0.4473237 |
| GO:BP | GO:0070341 | fat cell proliferation | 1 | PPARD | 11 | 0.4476804 |
| GO:BP | GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 1 | POLR2G | 64 | 0.4490342 |
| GO:BP | GO:0002090 | regulation of receptor internalization | 1 | ANKRD13D | 50 | 0.4490342 |
| GO:BP | GO:0045087 | innate immune response | 2 | PLEKHM2,RNF19B | 516 | 0.4497815 |
| GO:BP | GO:0044419 | biological process involved in interspecies interaction between organisms | 3 | PLEKHM2,HDAC1,RNF19B | 988 | 0.4500500 |
| GO:BP | GO:0034766 | negative regulation of monoatomic ion transmembrane transport | 1 | PPP3CB | 70 | 0.4501779 |
| GO:BP | GO:0009174 | pyrimidine ribonucleoside monophosphate biosynthetic process | 1 | UPRT | 10 | 0.4520366 |
| GO:BP | GO:0046530 | photoreceptor cell differentiation | 2 | TTC8,RDH13 | 40 | 0.4520366 |
| GO:BP | GO:0060048 | cardiac muscle contraction | 1 | ADORA1 | 121 | 0.4520366 |
| GO:BP | GO:0090287 | regulation of cellular response to growth factor stimulus | 1 | HDAC1 | 261 | 0.4522134 |
| GO:BP | GO:0002520 | immune system development | 1 | LMO4 | 144 | 0.4533885 |
| GO:BP | GO:0042307 | positive regulation of protein import into nucleus | 1 | RAN | 33 | 0.4546338 |
| GO:BP | GO:0120039 | plasma membrane bounded cell projection morphogenesis | 2 | LYPLA2,LMO4 | 514 | 0.4553611 |
| GO:BP | GO:0007368 | determination of left/right symmetry | 4 | CLUAP1,MKS1,IFT52,BBS7 | 96 | 0.4555867 |
| GO:BP | GO:0033233 | regulation of protein sumoylation | 1 | PIAS4 | 21 | 0.4567194 |
| GO:BP | GO:1903556 | negative regulation of tumor necrosis factor superfamily cytokine production | 1 | GSTP1 | 33 | 0.4567845 |
| GO:BP | GO:0051403 | stress-activated MAPK cascade | 5 | AIDA,GSTP1,PAFAH1B1,MAP2K7,MAP4K3 | 188 | 0.4574982 |
| GO:BP | GO:0043588 | skin development | 1 | HDAC1 | 179 | 0.4581143 |
| GO:BP | GO:0017145 | stem cell division | 1 | PAFAH1B1 | 25 | 0.4581175 |
| GO:BP | GO:0031644 | regulation of nervous system process | 1 | ADORA1 | 87 | 0.4585746 |
| GO:BP | GO:0048858 | cell projection morphogenesis | 2 | LYPLA2,LMO4 | 518 | 0.4587326 |
| GO:BP | GO:1905953 | negative regulation of lipid localization | 1 | CRY1 | 31 | 0.4588891 |
| GO:BP | GO:0043923 | positive regulation by host of viral transcription | 1 | SMARCB1 | 18 | 0.4592765 |
| GO:BP | GO:0006366 | transcription by RNA polymerase II | 24 | HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,ZNF195,ZNF408,POLR2G,KAT5,BRMS1,RBM14,PCF11,MED17,CDK4,TBK1,CRY1,TRIAP1,KMT5A,GTF2F2,ING1,SNAPC1 | 1851 | 0.4592765 |
| GO:BP | GO:0021988 | olfactory lobe development | 1 | TTC8 | 22 | 0.4592765 |
| GO:BP | GO:0038095 | Fc-epsilon receptor signaling pathway | 1 | MAP2K7 | 17 | 0.4592765 |
| GO:BP | GO:0046339 | diacylglycerol metabolic process | 1 | PGS1 | 24 | 0.4592765 |
| GO:BP | GO:0032880 | regulation of protein localization | 1 | PLEKHM2 | 718 | 0.4592765 |
| GO:BP | GO:0019751 | polyol metabolic process | 1 | IPMK | 82 | 0.4592765 |
| GO:BP | GO:0043248 | proteasome assembly | 1 | PSMG3 | 14 | 0.4592765 |
| GO:BP | GO:0044403 | biological process involved in symbiotic interaction | 1 | HDAC1 | 225 | 0.4592765 |
| GO:BP | GO:0051345 | positive regulation of hydrolase activity | 1 | ASAP3 | 412 | 0.4596026 |
| GO:BP | GO:1901096 | regulation of autophagosome maturation | 1 | TMEM39A | 16 | 0.4596026 |
| GO:BP | GO:0006644 | phospholipid metabolic process | 9 | PIGC,IPMK,PAFAH1B1,GDPD1,PGS1,TMEM150A,INPP1,TAMM41,SACM1L | 307 | 0.4596026 |
| GO:BP | GO:0060560 | developmental growth involved in morphogenesis | 2 | PPP3CB,BDNF | 207 | 0.4596026 |
| GO:BP | GO:0099170 | postsynaptic modulation of chemical synaptic transmission | 1 | EIF4A3 | 22 | 0.4596026 |
| GO:BP | GO:0036314 | response to sterol | 1 | OSBPL7 | 20 | 0.4596026 |
| GO:BP | GO:0000271 | polysaccharide biosynthetic process | 1 | PPP1CA | 54 | 0.4596026 |
| GO:BP | GO:0018216 | peptidyl-arginine methylation | 1 | PRMT9 | 14 | 0.4601494 |
| GO:BP | GO:0006515 | protein quality control for misfolded or incompletely synthesized proteins | 1 | PEX12 | 31 | 0.4607470 |
| GO:BP | GO:0009914 | hormone transport | 2 | ADORA1,PPP3CB | 216 | 0.4612911 |
| GO:BP | GO:1903541 | regulation of exosomal secretion | 1 | RAB7A | 15 | 0.4616490 |
| GO:BP | GO:1901698 | response to nitrogen compound | 1 | AGTRAP | 810 | 0.4616490 |
| GO:BP | GO:0051234 | establishment of localization | 2 | ICMT,PEX14 | 3454 | 0.4619455 |
| GO:BP | GO:0042596 | fear response | 2 | RPS6KB1,PRKAR1B | 33 | 0.4624596 |
| GO:BP | GO:0055075 | potassium ion homeostasis | 1 | SLC12A4 | 22 | 0.4624596 |
| GO:BP | GO:0061099 | negative regulation of protein tyrosine kinase activity | 1 | CHMP6 | 23 | 0.4624680 |
| GO:BP | GO:0045088 | regulation of innate immune response | 4 | TRIM3,KAT5,RBM14,TBK1 | 261 | 0.4626478 |
| GO:BP | GO:0046889 | positive regulation of lipid biosynthetic process | 2 | KAT5,RPTOR | 64 | 0.4626478 |
| GO:BP | GO:0031145 | anaphase-promoting complex-dependent catabolic process | 1 | FZR1 | 23 | 0.4626478 |
| GO:BP | GO:0140374 | antiviral innate immune response | 1 | TBK1 | 35 | 0.4626478 |
| GO:BP | GO:0048545 | response to steroid hormone | 1 | HDAC1 | 237 | 0.4626478 |
| GO:BP | GO:0009887 | animal organ morphogenesis | 2 | CPLANE2,HDAC1 | 725 | 0.4626616 |
| GO:BP | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 1 | BAK1 | 13 | 0.4628527 |
| GO:BP | GO:0045806 | negative regulation of endocytosis | 1 | ANKRD13D | 56 | 0.4628594 |
| GO:BP | GO:0009581 | detection of external stimulus | 1 | ADORA1 | 66 | 0.4629291 |
| GO:BP | GO:0051222 | positive regulation of protein transport | 2 | PPP3CB,ANKRD1 | 245 | 0.4636468 |
| GO:BP | GO:0033559 | unsaturated fatty acid metabolic process | 2 | GSTP1,CES2 | 67 | 0.4636468 |
| GO:BP | GO:1905897 | regulation of response to endoplasmic reticulum stress | 3 | AQP11,BAK1,UFL1 | 76 | 0.4636468 |
| GO:BP | GO:1901077 | regulation of relaxation of muscle | 1 | SRI | 8 | 0.4636468 |
| GO:BP | GO:0046467 | membrane lipid biosynthetic process | 1 | PIGC | 124 | 0.4646030 |
| GO:BP | GO:1903531 | negative regulation of secretion by cell | 2 | ADORA1,CRY1 | 101 | 0.4647265 |
| GO:BP | GO:2000232 | regulation of rRNA processing | 1 | RIOK2 | 16 | 0.4651331 |
| GO:BP | GO:0097091 | synaptic vesicle clustering | 1 | CTBP1 | 16 | 0.4662453 |
| GO:BP | GO:0043269 | regulation of monoatomic ion transport | 3 | ADORA1,PSEN2,PPP3CB | 369 | 0.4665037 |
| GO:BP | GO:0035296 | regulation of tube diameter | 1 | ADORA1 | 98 | 0.4665037 |
| GO:BP | GO:0097746 | blood vessel diameter maintenance | 1 | ADORA1 | 98 | 0.4665037 |
| GO:BP | GO:0043303 | mast cell degranulation | 1 | C12orf4 | 29 | 0.4665037 |
| GO:BP | GO:0010557 | positive regulation of macromolecule biosynthetic process | 11 | PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,JMJD4,ECD,PPP3CB,ANKRD1,BLOC1S2 | 1895 | 0.4665037 |
| GO:BP | GO:1901976 | regulation of cell cycle checkpoint | 1 | CRY1 | 43 | 0.4665037 |
| GO:BP | GO:0042308 | negative regulation of protein import into nucleus | 1 | RAB23 | 13 | 0.4665037 |
| GO:BP | GO:0009582 | detection of abiotic stimulus | 1 | ADORA1 | 67 | 0.4674849 |
| GO:BP | GO:0042063 | gliogenesis | 1 | HDAC1 | 244 | 0.4674849 |
| GO:BP | GO:0032990 | cell part morphogenesis | 2 | LYPLA2,LMO4 | 538 | 0.4674849 |
| GO:BP | GO:0060078 | regulation of postsynaptic membrane potential | 1 | ADORA1 | 85 | 0.4674849 |
| GO:BP | GO:0035150 | regulation of tube size | 1 | ADORA1 | 98 | 0.4674849 |
| GO:BP | GO:0007041 | lysosomal transport | 4 | CHMP1A,CHMP6,RAB7A,ZFYVE16 | 114 | 0.4675004 |
| GO:BP | GO:0051156 | glucose 6-phosphate metabolic process | 1 | RPTOR | 25 | 0.4681940 |
| GO:BP | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation | 1 | RPTOR | 23 | 0.4681940 |
| GO:BP | GO:0007283 | spermatogenesis | 5 | PITHD1,HERC4,KAT5,ANKRD49,PAFAH1B2 | 333 | 0.4682453 |
| GO:BP | GO:2000379 | positive regulation of reactive oxygen species metabolic process | 1 | GSTP1 | 45 | 0.4682453 |
| GO:BP | GO:0097421 | liver regeneration | 1 | SRSF1 | 23 | 0.4682453 |
| GO:BP | GO:0006801 | superoxide metabolic process | 1 | GSTP1 | 41 | 0.4682453 |
| GO:BP | GO:0045937 | positive regulation of phosphate metabolic process | 3 | LMO4,DUSP12,ADORA1 | 559 | 0.4684691 |
| GO:BP | GO:0010562 | positive regulation of phosphorus metabolic process | 3 | LMO4,DUSP12,ADORA1 | 559 | 0.4684691 |
| GO:BP | GO:2000272 | negative regulation of signaling receptor activity | 1 | CHMP6 | 22 | 0.4685371 |
| GO:BP | GO:0050775 | positive regulation of dendrite morphogenesis | 1 | PAFAH1B1 | 32 | 0.4685371 |
| GO:BP | GO:0031341 | regulation of cell killing | 1 | PPP3CB | 40 | 0.4685371 |
| GO:BP | GO:0043280 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 2 | DIABLO,PML | 92 | 0.4685371 |
| GO:BP | GO:0010648 | negative regulation of cell communication | 20 | HDAC1,LMNA,ADORA1,AIDA,HERC4,BDNF,BRMS1,GSTP1,CRY1,TRIAP1,UBAC2,ING1,WDR24,NXN,PAFAH1B1,NLE1,RPS6KB1,CHMP6,RIOK3,PIAS4 | 1087 | 0.4685371 |
| GO:BP | GO:0006337 | nucleosome disassembly | 1 | SMARCB1 | 15 | 0.4685371 |
| GO:BP | GO:1904062 | regulation of monoatomic cation transmembrane transport | 2 | PSEN2,PPP3CB | 232 | 0.4687869 |
| GO:BP | GO:0015868 | purine ribonucleotide transport | 1 | SLC35B1 | 23 | 0.4687869 |
| GO:BP | GO:0001768 | establishment of T cell polarity | 1 | TRAF3IP2 | 10 | 0.4691072 |
| GO:BP | GO:0140353 | lipid export from cell | 1 | CRY1 | 28 | 0.4698229 |
| GO:BP | GO:1990138 | neuron projection extension | 4 | PPP3CB,PAFAH1B1,IMPACT,BCL11A | 149 | 0.4698229 |
| GO:BP | GO:0048675 | axon extension | 3 | PPP3CB,PAFAH1B1,BCL11A | 108 | 0.4704552 |
| GO:BP | GO:0006865 | amino acid transport | 1 | ADORA1 | 103 | 0.4712148 |
| GO:BP | GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 1 | PPP1CA | 53 | 0.4712148 |
| GO:BP | GO:0038034 | signal transduction in absence of ligand | 1 | PPP1CA | 53 | 0.4712148 |
| GO:BP | GO:0000281 | mitotic cytokinesis | 2 | CHMP1A,CHMP6 | 83 | 0.4713140 |
| GO:BP | GO:0051153 | regulation of striated muscle cell differentiation | 1 | BDNF | 66 | 0.4716722 |
| GO:BP | GO:0032940 | secretion by cell | 4 | CPLANE2,ADORA1,PPP3CB,ANKRD1 | 572 | 0.4720194 |
| GO:BP | GO:1902531 | regulation of intracellular signal transduction | 25 | ARHGEF10L,HDAC1,ADORA1,AIDA,PPP3CB,SYNPO2L,ANKRD1,RAD9A,GSTP1,ARAP1,TBK1,CRY1,TRIAP1,KMT5A,RALGAPA1,PML,WDR24,TERF2IP,PAFAH1B1,HEXIM1,RPTOR,RIOK3,PIAS4,MAP2K7,SYDE1 | 1317 | 0.4720194 |
| GO:BP | GO:0032365 | intracellular lipid transport | 1 | GLTP | 43 | 0.4720194 |
| GO:BP | GO:0045842 | positive regulation of mitotic metaphase/anaphase transition | 1 | MAD1L1 | 14 | 0.4730291 |
| GO:BP | GO:0002279 | mast cell activation involved in immune response | 1 | C12orf4 | 30 | 0.4731253 |
| GO:BP | GO:0045022 | early endosome to late endosome transport | 2 | RAB7A,SNX12 | 42 | 0.4731253 |
| GO:BP | GO:0071840 | cellular component organization or biogenesis | 6 | WRAP73,PEX14,PLEKHM2,CPLANE2,ARHGEF10L,ASAP3 | 5317 | 0.4731253 |
| GO:BP | GO:0014074 | response to purine-containing compound | 1 | ADORA1 | 108 | 0.4744307 |
| GO:BP | GO:0097306 | cellular response to alcohol | 2 | CDK4,OSBPL7 | 72 | 0.4744906 |
| GO:BP | GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 1 | PEX14 | 1203 | 0.4762819 |
| GO:BP | GO:0031098 | stress-activated protein kinase signaling cascade | 5 | AIDA,GSTP1,PAFAH1B1,MAP2K7,MAP4K3 | 194 | 0.4765355 |
| GO:BP | GO:0090263 | positive regulation of canonical Wnt signaling pathway | 2 | GSKIP,NLE1 | 90 | 0.4772417 |
| GO:BP | GO:0071577 | zinc ion transmembrane transport | 1 | SLC39A3 | 22 | 0.4773484 |
| GO:BP | GO:2000291 | regulation of myoblast proliferation | 1 | PPARD | 11 | 0.4773700 |
| GO:BP | GO:0014857 | regulation of skeletal muscle cell proliferation | 1 | PPARD | 10 | 0.4773700 |
| GO:BP | GO:0043010 | camera-type eye development | 1 | HDAC1 | 237 | 0.4779426 |
| GO:BP | GO:0050872 | white fat cell differentiation | 1 | CTBP1 | 15 | 0.4780143 |
| GO:BP | GO:0002448 | mast cell mediated immunity | 1 | C12orf4 | 32 | 0.4780143 |
| GO:BP | GO:0051284 | positive regulation of sequestering of calcium ion | 1 | SRI | 13 | 0.4783635 |
| GO:BP | GO:0021954 | central nervous system neuron development | 2 | PAFAH1B1,RAC3 | 64 | 0.4783635 |
| GO:BP | GO:0060972 | left/right pattern formation | 4 | CLUAP1,MKS1,IFT52,BBS7 | 101 | 0.4783635 |
| GO:BP | GO:0071347 | cellular response to interleukin-1 | 1 | ANKRD1 | 64 | 0.4789895 |
| GO:BP | GO:0010761 | fibroblast migration | 2 | PML,MACIR | 52 | 0.4789895 |
| GO:BP | GO:0099072 | regulation of postsynaptic membrane neurotransmitter receptor levels | 1 | AP2A2 | 72 | 0.4789895 |
| GO:BP | GO:0055085 | transmembrane transport | 1 | PEX14 | 1016 | 0.4794424 |
| GO:BP | GO:0009743 | response to carbohydrate | 2 | PPP3CB,KAT5 | 161 | 0.4794424 |
| GO:BP | GO:0090277 | positive regulation of peptide hormone secretion | 1 | PPP3CB | 72 | 0.4794424 |
| GO:BP | GO:0039531 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway | 1 | TRIM3 | 67 | 0.4797750 |
| GO:BP | GO:0006044 | N-acetylglucosamine metabolic process | 1 | GNPDA2 | 16 | 0.4801175 |
| GO:BP | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly | 1 | ZDHHC12 | 9 | 0.4801175 |
| GO:BP | GO:1904951 | positive regulation of establishment of protein localization | 2 | PPP3CB,ANKRD1 | 261 | 0.4801175 |
| GO:BP | GO:0044839 | cell cycle G2/M phase transition | 5 | CDK4,FZR1,MTA3,HUS1,RINT1 | 145 | 0.4801175 |
| GO:BP | GO:0009893 | positive regulation of metabolic process | 52 | PITHD1,HDAC1,RNF19B,MED8,LMO4,VPS72,LMNA,DUSP12,ADORA1,JMJD4,ECD,PPP3CB,ANKRD1,BLOC1S2,BDNF,POLR2G,KAT5,BRMS1,RBM14,GSTP1,ARAP1,MED17,ANKRD49,PAFAH1B2,TBK1,CRY1,PRKAB1,TRIAP1,DIABLO,GTF2F2,ING1,BRF1,TRIP4,PML,WDR24,ARL2BP,E2F4,ZFP90,TERF2IP,ZNF287,PEX12,OSBPL7,SRSF1,RPS6KB1,EIF4A3,RPTOR,RIOK3,IMPACT,MOB3A,FZR1,PIAS4,MAP2K7 | 2846 | 0.4801175 |
| GO:BP | GO:0060429 | epithelium development | 3 | CPLANE2,HDAC1,LMO4 | 847 | 0.4801175 |
| GO:BP | GO:0046112 | nucleobase biosynthetic process | 1 | PAICS | 18 | 0.4801175 |
| GO:BP | GO:0039692 | single stranded viral RNA replication via double stranded DNA intermediate | 1 | SMARCB1 | 16 | 0.4801175 |
| GO:BP | GO:0046040 | IMP metabolic process | 1 | PAICS | 15 | 0.4801175 |
| GO:BP | GO:0002098 | tRNA wobble uridine modification | 1 | MTO1 | 16 | 0.4801175 |
| GO:BP | GO:0070373 | negative regulation of ERK1 and ERK2 cascade | 1 | GSTP1 | 58 | 0.4802211 |
| GO:BP | GO:0097581 | lamellipodium organization | 1 | ARFIP2 | 77 | 0.4802211 |
| GO:BP | GO:0010770 | positive regulation of cell morphogenesis | 1 | PAFAH1B1 | 33 | 0.4804555 |
| GO:BP | GO:1900102 | negative regulation of endoplasmic reticulum unfolded protein response | 1 | UFL1 | 16 | 0.4812054 |
| GO:BP | GO:0060341 | regulation of cellular localization | 1 | PLEKHM2 | 804 | 0.4823726 |
| GO:BP | GO:0001767 | establishment of lymphocyte polarity | 1 | TRAF3IP2 | 11 | 0.4836923 |
| GO:BP | GO:0045744 | negative regulation of G protein-coupled receptor signaling pathway | 1 | CRY1 | 36 | 0.4836923 |
| GO:BP | GO:0097398 | cellular response to interleukin-17 | 1 | TRAF3IP2 | 12 | 0.4836923 |
| GO:BP | GO:0040008 | regulation of growth | 13 | BDNF,EI24,CDK4,ING1,PML,PAFAH1B1,RPS6KB1,RPTOR,SERTAD1,BCL11A,OGFR,N6AMT1,SMARCB1 | 493 | 0.4836923 |
| GO:BP | GO:0098815 | modulation of excitatory postsynaptic potential | 2 | EIF4A3,PRKAR1B | 44 | 0.4836923 |
| GO:BP | GO:0023035 | CD40 signaling pathway | 1 | TRAF3IP2 | 11 | 0.4836923 |
| GO:BP | GO:0006829 | zinc ion transport | 1 | SLC39A3 | 23 | 0.4841700 |
| GO:BP | GO:0071229 | cellular response to acid chemical | 3 | RPTOR,BCL11A,CPEB4 | 72 | 0.4843451 |
| GO:BP | GO:1990748 | cellular detoxification | 2 | GSTP1,NXN | 79 | 0.4848154 |
| GO:BP | GO:0032414 | positive regulation of ion transmembrane transporter activity | 1 | PPP3CB | 83 | 0.4848154 |
| GO:BP | GO:0002886 | regulation of myeloid leukocyte mediated immunity | 1 | C12orf4 | 32 | 0.4848154 |
| GO:BP | GO:0045944 | positive regulation of transcription by RNA polymerase II | 3 | HDAC1,MED8,LMO4 | 915 | 0.4852011 |
| GO:BP | GO:0070542 | response to fatty acid | 1 | CDK4 | 38 | 0.4857622 |
| GO:BP | GO:0006878 | intracellular copper ion homeostasis | 1 | COX19 | 15 | 0.4857622 |
| GO:BP | GO:0048232 | male gamete generation | 5 | PITHD1,HERC4,KAT5,ANKRD49,PAFAH1B2 | 346 | 0.4857622 |
| GO:BP | GO:0045773 | positive regulation of axon extension | 1 | PAFAH1B1 | 32 | 0.4877132 |
| GO:BP | GO:1902101 | positive regulation of metaphase/anaphase transition of cell cycle | 1 | MAD1L1 | 14 | 0.4877132 |
| GO:BP | GO:0021799 | cerebral cortex radially oriented cell migration | 1 | PAFAH1B1 | 28 | 0.4877132 |
| GO:BP | GO:0007186 | G protein-coupled receptor signaling pathway | 1 | AGTRAP | 387 | 0.4883930 |
| GO:BP | GO:0009162 | deoxyribonucleoside monophosphate metabolic process | 1 | DGUOK | 18 | 0.4883930 |
| GO:BP | GO:0000422 | autophagy of mitochondrion | 1 | ARFIP2 | 90 | 0.4885481 |
| GO:BP | GO:0061726 | mitochondrion disassembly | 1 | ARFIP2 | 90 | 0.4885481 |
| GO:BP | GO:0050905 | neuromuscular process | 3 | PAFAH1B1,RPS6KB1,RAC3 | 110 | 0.4885630 |
| GO:BP | GO:0035640 | exploration behavior | 1 | EIF4A3 | 21 | 0.4888796 |
| GO:BP | GO:0033013 | tetrapyrrole metabolic process | 2 | RSAD1,SRRD | 51 | 0.4890063 |
| GO:BP | GO:1902904 | negative regulation of supramolecular fiber organization | 2 | ARAP1,NAV3 | 136 | 0.4890063 |
| GO:BP | GO:0010738 | regulation of protein kinase A signaling | 1 | SPATC1L | 13 | 0.4892507 |
| GO:BP | GO:0010669 | epithelial structure maintenance | 1 | MKS1 | 15 | 0.4892507 |
| GO:BP | GO:0010842 | retina layer formation | 1 | RDH13 | 16 | 0.4892507 |
| GO:BP | GO:0046321 | positive regulation of fatty acid oxidation | 1 | PPARD | 15 | 0.4892507 |
| GO:BP | GO:0051503 | adenine nucleotide transport | 1 | SLC35B1 | 25 | 0.4892507 |
| GO:BP | GO:0014841 | skeletal muscle satellite cell proliferation | 1 | PPARD | 13 | 0.4892507 |
| GO:BP | GO:0060914 | heart formation | 1 | MKS1 | 28 | 0.4892507 |
| GO:BP | GO:0061640 | cytoskeleton-dependent cytokinesis | 3 | CHMP1A,CHMP6,SEPTIN2 | 106 | 0.4892507 |
| GO:BP | GO:0005977 | glycogen metabolic process | 1 | PPP1CA | 64 | 0.4892507 |
| GO:BP | GO:0061462 | protein localization to lysosome | 2 | RAB7A,ZFYVE16 | 47 | 0.4892507 |
| GO:BP | GO:0045063 | T-helper 1 cell differentiation | 1 | STAT4 | 15 | 0.4892507 |
| GO:BP | GO:0006690 | icosanoid metabolic process | 2 | GSTP1,CES2 | 60 | 0.4895604 |
| GO:BP | GO:0006869 | lipid transport | 1 | STX12 | 269 | 0.4895604 |
| GO:BP | GO:0032527 | protein exit from endoplasmic reticulum | 1 | UBAC2 | 43 | 0.4895604 |
| GO:BP | GO:0032986 | protein-DNA complex disassembly | 1 | SMARCB1 | 17 | 0.4896535 |
| GO:BP | GO:0042790 | nucleolar large rRNA transcription by RNA polymerase I | 1 | SMARCB1 | 21 | 0.4896535 |
| GO:BP | GO:0006826 | iron ion transport | 1 | SLC48A1 | 42 | 0.4898376 |
| GO:BP | GO:0031113 | regulation of microtubule polymerization | 1 | NAV3 | 51 | 0.4905610 |
| GO:BP | GO:0009226 | nucleotide-sugar biosynthetic process | 1 | GNPDA2 | 19 | 0.4905610 |
| GO:BP | GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 2 | BRMS1,PIAS4 | 66 | 0.4908343 |
| GO:BP | GO:0042994 | cytoplasmic sequestering of transcription factor | 1 | SRI | 15 | 0.4908343 |
| GO:BP | GO:0070588 | calcium ion transmembrane transport | 2 | PSEN2,PPP3CB | 221 | 0.4908495 |
| GO:BP | GO:0009168 | purine ribonucleoside monophosphate biosynthetic process | 1 | PAICS | 18 | 0.4911232 |
| GO:BP | GO:0006937 | regulation of muscle contraction | 1 | ADORA1 | 130 | 0.4912122 |
| GO:BP | GO:0070979 | protein K11-linked ubiquitination | 1 | FZR1 | 29 | 0.4912122 |
| GO:BP | GO:0046475 | glycerophospholipid catabolic process | 1 | GDPD1 | 21 | 0.4912122 |
| GO:BP | GO:0055088 | lipid homeostasis | 1 | ADORA1 | 116 | 0.4912122 |
| GO:BP | GO:0048854 | brain morphogenesis | 1 | PAFAH1B1 | 27 | 0.4913180 |
| GO:BP | GO:0042886 | amide transport | 2 | ADORA1,PPP3CB | 236 | 0.4913293 |
| GO:BP | GO:0045862 | positive regulation of proteolysis | 1 | RNF19B | 289 | 0.4914059 |
| GO:BP | GO:0046890 | regulation of lipid biosynthetic process | 2 | KAT5,CDK4 | 136 | 0.4914059 |
| GO:BP | GO:0042221 | response to chemical | 2 | PEX14,AGTRAP | 2455 | 0.4914059 |
| GO:BP | GO:0042058 | regulation of epidermal growth factor receptor signaling pathway | 2 | CHMP6,RAB7A | 53 | 0.4914059 |
| GO:BP | GO:1903020 | positive regulation of glycoprotein metabolic process | 1 | RAB1A | 17 | 0.4914059 |
| GO:BP | GO:0045926 | negative regulation of growth | 5 | EI24,ING1,PML,SERTAD1,BCL11A | 204 | 0.4921146 |
| GO:BP | GO:0009266 | response to temperature stimulus | 1 | ADORA1 | 122 | 0.4921146 |
| GO:BP | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1 | UTP6 | 37 | 0.4930329 |
| GO:BP | GO:0006633 | fatty acid biosynthetic process | 2 | GSTP1,PRKAB1 | 106 | 0.4934804 |
| GO:BP | GO:0032012 | regulation of ARF protein signal transduction | 1 | ARFGEF2 | 18 | 0.4935099 |
| GO:BP | GO:0032011 | ARF protein signal transduction | 1 | ARFGEF2 | 18 | 0.4935099 |
| GO:BP | GO:0051101 | regulation of DNA binding | 2 | ERCC4,ZFP90 | 102 | 0.4935099 |
| GO:BP | GO:1990182 | exosomal secretion | 1 | RAB7A | 18 | 0.4935099 |
| GO:BP | GO:0044042 | glucan metabolic process | 1 | PPP1CA | 65 | 0.4936925 |
| GO:BP | GO:0097062 | dendritic spine maintenance | 1 | PICK1 | 16 | 0.4938851 |
| GO:BP | GO:0050767 | regulation of neurogenesis | 1 | HDAC1 | 300 | 0.4940053 |
| GO:BP | GO:0045332 | phospholipid translocation | 1 | TRIAP1 | 32 | 0.4940053 |
| GO:BP | GO:0018195 | peptidyl-arginine modification | 1 | PRMT9 | 17 | 0.4940053 |
| GO:BP | GO:0097396 | response to interleukin-17 | 1 | TRAF3IP2 | 13 | 0.4949210 |
| GO:BP | GO:0040011 | locomotion | 4 | HDAC1,LMO4,LMNA,ADORA1 | 854 | 0.4957162 |
| GO:BP | GO:0002698 | negative regulation of immune effector process | 1 | PPP3CB | 59 | 0.4960745 |
| GO:BP | GO:0098927 | vesicle-mediated transport between endosomal compartments | 2 | RAB7A,SNX12 | 44 | 0.4960745 |
| GO:BP | GO:0031345 | negative regulation of cell projection organization | 4 | RAB3IP,PAFAH1B1,BCL11A,DGUOK | 154 | 0.4960745 |
| GO:BP | GO:0006006 | glucose metabolic process | 1 | DUSP12 | 153 | 0.4969547 |
| GO:BP | GO:0140352 | export from cell | 1 | CPLANE2 | 616 | 0.4970269 |
| GO:BP | GO:0031328 | positive regulation of cellular biosynthetic process | 11 | PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,JMJD4,ECD,PPP3CB,ANKRD1,BLOC1S2 | 1957 | 0.4974335 |
| GO:BP | GO:0009130 | pyrimidine nucleoside monophosphate biosynthetic process | 1 | UPRT | 13 | 0.4974335 |
| GO:BP | GO:0008544 | epidermis development | 1 | HDAC1 | 213 | 0.4974335 |
| GO:BP | GO:0046049 | UMP metabolic process | 1 | UPRT | 11 | 0.4974335 |
| GO:BP | GO:0048704 | embryonic skeletal system morphogenesis | 2 | EIF4A3,SLC39A3 | 54 | 0.4974335 |
| GO:BP | GO:0006805 | xenobiotic metabolic process | 2 | GSTP1,CES2 | 56 | 0.4974335 |
| GO:BP | GO:0099560 | synaptic membrane adhesion | 1 | LRFN3 | 21 | 0.4975703 |
| GO:BP | GO:0051048 | negative regulation of secretion | 1 | ADORA1 | 111 | 0.4993120 |
| GO:BP | GO:0009123 | nucleoside monophosphate metabolic process | 3 | DGUOK,PAICS,UPRT | 64 | 0.4993120 |
| GO:BP | GO:1903859 | regulation of dendrite extension | 1 | BCL11A | 18 | 0.4995749 |
| GO:BP | GO:0009886 | post-embryonic animal morphogenesis | 1 | BAK1 | 11 | 0.5003485 |
| GO:BP | GO:0015865 | purine nucleotide transport | 1 | SLC35B1 | 25 | 0.5008431 |
| GO:BP | GO:0033189 | response to vitamin A | 1 | PPARD | 13 | 0.5013050 |
| GO:BP | GO:0099587 | inorganic ion import across plasma membrane | 1 | PPP3CB | 71 | 0.5023993 |
| GO:BP | GO:0002456 | T cell mediated immunity | 1 | PPP3CB | 61 | 0.5023993 |
| GO:BP | GO:0098659 | inorganic cation import across plasma membrane | 1 | PPP3CB | 71 | 0.5023993 |
| GO:BP | GO:0010839 | negative regulation of keratinocyte proliferation | 1 | IFT52 | 19 | 0.5024371 |
| GO:BP | GO:0006144 | purine nucleobase metabolic process | 1 | PAICS | 15 | 0.5024371 |
| GO:BP | GO:0006699 | bile acid biosynthetic process | 1 | OSBPL7 | 26 | 0.5026046 |
| GO:BP | GO:0060986 | endocrine hormone secretion | 1 | CRY1 | 35 | 0.5026572 |
| GO:BP | GO:0021955 | central nervous system neuron axonogenesis | 1 | PAFAH1B1 | 33 | 0.5026572 |
| GO:BP | GO:0060999 | positive regulation of dendritic spine development | 1 | PAFAH1B1 | 37 | 0.5026572 |
| GO:BP | GO:0045912 | negative regulation of carbohydrate metabolic process | 1 | CRY1 | 41 | 0.5026572 |
| GO:BP | GO:0052547 | regulation of peptidase activity | 1 | HDAC1 | 265 | 0.5027930 |
| GO:BP | GO:0046165 | alcohol biosynthetic process | 1 | IPMK | 111 | 0.5034777 |
| GO:BP | GO:0010649 | regulation of cell communication by electrical coupling | 1 | SRI | 17 | 0.5040069 |
| GO:BP | GO:0060562 | epithelial tube morphogenesis | 5 | LMO4,PPP1CA,PML,CLUAP1,MKS1 | 276 | 0.5048971 |
| GO:BP | GO:0050806 | positive regulation of synaptic transmission | 1 | ADORA1 | 110 | 0.5051332 |
| GO:BP | GO:0097734 | extracellular exosome biogenesis | 1 | RAB7A | 18 | 0.5051332 |
| GO:BP | GO:0009891 | positive regulation of biosynthetic process | 11 | PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,JMJD4,ECD,PPP3CB,ANKRD1,BLOC1S2 | 1971 | 0.5059076 |
| GO:BP | GO:0008610 | lipid biosynthetic process | 11 | PIGC,IPMK,KAT5,GSTP1,CDK4,PRKAB1,HSD17B1,OSBPL7,PGS1,RPTOR,CERS4 | 563 | 0.5062848 |
| GO:BP | GO:0034219 | carbohydrate transmembrane transport | 4 | AQP11,RPS6KB1,PPARD,MFSD4B | 95 | 0.5063256 |
| GO:BP | GO:0007006 | mitochondrial membrane organization | 1 | BLOC1S2 | 112 | 0.5064017 |
| GO:BP | GO:0061709 | reticulophagy | 1 | UFL1 | 18 | 0.5064017 |
| GO:BP | GO:1905952 | regulation of lipid localization | 2 | CRY1,TRIAP1 | 110 | 0.5064017 |
| GO:BP | GO:0001654 | eye development | 1 | HDAC1 | 273 | 0.5066868 |
| GO:BP | GO:0060443 | mammary gland morphogenesis | 1 | PML | 39 | 0.5073193 |
| GO:BP | GO:0032411 | positive regulation of transporter activity | 1 | PPP3CB | 93 | 0.5075022 |
| GO:BP | GO:0021675 | nerve development | 1 | BDNF | 63 | 0.5075022 |
| GO:BP | GO:0007417 | central nervous system development | 15 | HDAC1,LMO4,CLP1,SCYL1,GSTP1,PAFAH1B2,RAN,LIG4,TTC8,CLUAP1,PAFAH1B1,SRSF1,RAC3,PIAS4,SH3GL1 | 749 | 0.5075022 |
| GO:BP | GO:0034763 | negative regulation of transmembrane transport | 1 | PPP3CB | 96 | 0.5075022 |
| GO:BP | GO:0043271 | negative regulation of monoatomic ion transport | 1 | PPP3CB | 88 | 0.5075022 |
| GO:BP | GO:0055082 | intracellular chemical homeostasis | 5 | ADORA1,PPP3CB,KAT5,GSTP1,AQP11 | 498 | 0.5075549 |
| GO:BP | GO:0141086 | negative regulation of inflammasome-mediated signaling pathway | 1 | ZDHHC12 | 10 | 0.5081706 |
| GO:BP | GO:0032230 | positive regulation of synaptic transmission, GABAergic | 1 | ZDHHC12 | 10 | 0.5081706 |
| GO:BP | GO:0150063 | visual system development | 1 | HDAC1 | 274 | 0.5088515 |
| GO:BP | GO:0051928 | positive regulation of calcium ion transport | 1 | PPP3CB | 80 | 0.5093679 |
| GO:BP | GO:0010720 | positive regulation of cell development | 3 | HDAC1,BDNF,KAT5 | 317 | 0.5093679 |
| GO:BP | GO:0006796 | phosphate-containing compound metabolic process | 37 | LMO4,DUSP12,TIPRL,PIGC,ADORA1,AIDA,IPMK,PPP3CB,FRA10AC1,STK33,BDNF,CLP1,SCYL1,PPP1CA,GSTP1,CDK4,TBK1,PRKAB1,RAN,GSKIP,PPCDC,EFL1,WDR24,ARL2BP,TERF2IP,PAFAH1B1,INCA1,HEXIM1,GDPD1,RPS6KB1,PGS1,RPTOR,CHMP6,RIOK3,IMPACT,MOB3A,MAP2K7 | 2096 | 0.5103480 |
| GO:BP | GO:0098609 | cell-cell adhesion | 1 | CPLANE2 | 599 | 0.5113950 |
| GO:BP | GO:0097237 | cellular response to toxic substance | 2 | GSTP1,NXN | 85 | 0.5116384 |
| GO:BP | GO:0030520 | intracellular estrogen receptor signaling pathway | 2 | TRIP4,UFL1 | 41 | 0.5117837 |
| GO:BP | GO:0070129 | regulation of mitochondrial translation | 1 | METTL8 | 26 | 0.5120881 |
| GO:BP | GO:1900044 | regulation of protein K63-linked ubiquitination | 1 | UBE2V2 | 15 | 0.5121243 |
| GO:BP | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 1 | ADORA1 | 103 | 0.5121243 |
| GO:BP | GO:0035795 | negative regulation of mitochondrial membrane permeability | 1 | BAK1 | 17 | 0.5121243 |
| GO:BP | GO:0046627 | negative regulation of insulin receptor signaling pathway | 1 | RPS6KB1 | 31 | 0.5121243 |
| GO:BP | GO:0030540 | female genitalia development | 1 | BAK1 | 14 | 0.5121243 |
| GO:BP | GO:0043277 | apoptotic cell clearance | 2 | RAC3,RAB14 | 32 | 0.5121243 |
| GO:BP | GO:0040020 | regulation of meiotic nuclear division | 1 | FZR1 | 19 | 0.5121243 |
| GO:BP | GO:0097202 | activation of cysteine-type endopeptidase activity | 1 | BAK1 | 16 | 0.5121243 |
| GO:BP | GO:0010876 | lipid localization | 1 | STX12 | 307 | 0.5121243 |
| GO:BP | GO:1901978 | positive regulation of cell cycle checkpoint | 1 | MAD1L1 | 18 | 0.5121243 |
| GO:BP | GO:1902916 | positive regulation of protein polyubiquitination | 1 | UBE2V2 | 13 | 0.5121243 |
| GO:BP | GO:0048880 | sensory system development | 1 | HDAC1 | 276 | 0.5121243 |
| GO:BP | GO:0048873 | homeostasis of number of cells within a tissue | 1 | RAC3 | 25 | 0.5121243 |
| GO:BP | GO:0060395 | SMAD protein signal transduction | 1 | RBM14 | 64 | 0.5121243 |
| GO:BP | GO:0030900 | forebrain development | 1 | HDAC1 | 290 | 0.5126938 |
| GO:BP | GO:0031347 | regulation of defense response | 5 | ADORA1,TRIM3,KAT5,RBM14,GSTP1 | 476 | 0.5137264 |
| GO:BP | GO:0061001 | regulation of dendritic spine morphogenesis | 1 | PAFAH1B1 | 37 | 0.5137264 |
| GO:BP | GO:0031053 | primary miRNA processing | 1 | SRSF3 | 18 | 0.5137264 |
| GO:BP | GO:0046903 | secretion | 1 | CPLANE2 | 646 | 0.5138645 |
| GO:BP | GO:0009306 | protein secretion | 2 | PPP3CB,ANKRD1 | 261 | 0.5155965 |
| GO:BP | GO:0034204 | lipid translocation | 1 | TRIAP1 | 37 | 0.5158350 |
| GO:BP | GO:0007566 | embryo implantation | 2 | SYDE1,PPARD | 40 | 0.5164322 |
| GO:BP | GO:0097094 | craniofacial suture morphogenesis | 1 | RAB23 | 15 | 0.5166327 |
| GO:BP | GO:0035592 | establishment of protein localization to extracellular region | 2 | PPP3CB,ANKRD1 | 261 | 0.5166374 |
| GO:BP | GO:0006941 | striated muscle contraction | 1 | ADORA1 | 153 | 0.5166615 |
| GO:BP | GO:2001056 | positive regulation of cysteine-type endopeptidase activity | 2 | DIABLO,PML | 103 | 0.5169210 |
| GO:BP | GO:0008210 | estrogen metabolic process | 1 | HSD17B1 | 16 | 0.5171100 |
| GO:BP | GO:0002097 | tRNA wobble base modification | 1 | MTO1 | 19 | 0.5171100 |
| GO:BP | GO:0099504 | synaptic vesicle cycle | 6 | PPP3CB,SH3GL1,DNAJC5,CTBP1,PRKAR1B,PPP3CC | 162 | 0.5179145 |
| GO:BP | GO:0007266 | Rho protein signal transduction | 1 | SYNPO2L | 107 | 0.5179145 |
| GO:BP | GO:1900077 | negative regulation of cellular response to insulin stimulus | 1 | RPS6KB1 | 32 | 0.5188358 |
| GO:BP | GO:0045576 | mast cell activation | 1 | C12orf4 | 34 | 0.5188358 |
| GO:BP | GO:1901655 | cellular response to ketone | 2 | CDK4,RPS6KB1 | 82 | 0.5193347 |
| GO:BP | GO:0001659 | temperature homeostasis | 1 | ADORA1 | 134 | 0.5218109 |
| GO:BP | GO:0048535 | lymph node development | 1 | TRAF3IP2 | 11 | 0.5221141 |
| GO:BP | GO:0061008 | hepaticobiliary system development | 4 | SRSF1,MKS1,SMARCB1,PTCD2 | 113 | 0.5221141 |
| GO:BP | GO:0048524 | positive regulation of viral process | 2 | TMEM39A,RAB7A | 55 | 0.5221256 |
| GO:BP | GO:0040014 | regulation of multicellular organism growth | 1 | CDK4 | 53 | 0.5222301 |
| GO:BP | GO:0045787 | positive regulation of cell cycle | 7 | KAT5,CDK4,PAFAH1B1,RPS6KB1,RPTOR,MTA3,NSFL1C | 272 | 0.5222301 |
| GO:BP | GO:0048646 | anatomical structure formation involved in morphogenesis | 5 | HDAC1,LMO4,PPP3CB,SYNPO2L,ANKRD1 | 868 | 0.5227296 |
| GO:BP | GO:0007088 | regulation of mitotic nuclear division | 1 | BUB3 | 99 | 0.5228240 |
| GO:BP | GO:0045190 | isotype switching | 1 | LIG4 | 40 | 0.5234035 |
| GO:BP | GO:0002208 | somatic diversification of immunoglobulins involved in immune response | 1 | LIG4 | 40 | 0.5234035 |
| GO:BP | GO:0002204 | somatic recombination of immunoglobulin genes involved in immune response | 1 | LIG4 | 40 | 0.5234035 |
| GO:BP | GO:0061138 | morphogenesis of a branching epithelium | 3 | PPP1CA,PML,MKS1 | 143 | 0.5234035 |
| GO:BP | GO:0098754 | detoxification | 2 | GSTP1,NXN | 87 | 0.5234317 |
| GO:BP | GO:0043616 | keratinocyte proliferation | 2 | IFT52,PPARD | 39 | 0.5234317 |
| GO:BP | GO:0055070 | copper ion homeostasis | 1 | COX19 | 18 | 0.5237127 |
| GO:BP | GO:0071495 | cellular response to endogenous stimulus | 1 | AGTRAP | 1097 | 0.5237127 |
| GO:BP | GO:0071692 | protein localization to extracellular region | 2 | PPP3CB,ANKRD1 | 265 | 0.5238080 |
| GO:BP | GO:0032212 | positive regulation of telomere maintenance via telomerase | 1 | MAP2K7 | 31 | 0.5238080 |
| GO:BP | GO:0051973 | positive regulation of telomerase activity | 1 | MAP2K7 | 31 | 0.5238080 |
| GO:BP | GO:0048870 | cell motility | 5 | ASAP3,HDAC1,LMO4,LMNA,ADORA1 | 1169 | 0.5243036 |
| GO:BP | GO:0048569 | post-embryonic animal organ development | 1 | BAK1 | 15 | 0.5249783 |
| GO:BP | GO:1901970 | positive regulation of mitotic sister chromatid separation | 1 | MAD1L1 | 18 | 0.5249783 |
| GO:BP | GO:0006898 | receptor-mediated endocytosis | 2 | AP2A2,ANKRD13D | 194 | 0.5250075 |
| GO:BP | GO:0007616 | long-term memory | 1 | RPS6KB1 | 33 | 0.5250485 |
| GO:BP | GO:0051546 | keratinocyte migration | 1 | PPARD | 15 | 0.5254791 |
| GO:BP | GO:0006112 | energy reserve metabolic process | 1 | PPP1CA | 72 | 0.5254791 |
| GO:BP | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 1 | TTC8 | 46 | 0.5261730 |
| GO:BP | GO:0140112 | extracellular vesicle biogenesis | 1 | RAB7A | 20 | 0.5261730 |
| GO:BP | GO:0006400 | tRNA modification | 3 | TRMT61B,METTL8,MTO1 | 93 | 0.5262278 |
| GO:BP | GO:0031349 | positive regulation of defense response | 4 | TRIM3,KAT5,RBM14,TBK1 | 272 | 0.5262278 |
| GO:BP | GO:0070555 | response to interleukin-1 | 1 | ANKRD1 | 82 | 0.5266032 |
| GO:BP | GO:1990573 | potassium ion import across plasma membrane | 1 | SLC12A4 | 28 | 0.5266438 |
| GO:BP | GO:0098542 | defense response to other organism | 1 | PLEKHM2 | 638 | 0.5266438 |
| GO:BP | GO:0009173 | pyrimidine ribonucleoside monophosphate metabolic process | 1 | UPRT | 13 | 0.5268133 |
| GO:BP | GO:0061157 | mRNA destabilization | 1 | POLR2G | 92 | 0.5277814 |
| GO:BP | GO:1905606 | regulation of presynapse assembly | 1 | LRFN3 | 23 | 0.5282889 |
| GO:BP | GO:0099174 | regulation of presynapse organization | 1 | LRFN3 | 23 | 0.5282889 |
| GO:BP | GO:1901890 | positive regulation of cell junction assembly | 1 | BDNF | 81 | 0.5283757 |
| GO:BP | GO:0006687 | glycosphingolipid metabolic process | 1 | GLTP | 49 | 0.5286844 |
| GO:BP | GO:0006793 | phosphorus metabolic process | 37 | LMO4,DUSP12,TIPRL,PIGC,ADORA1,AIDA,IPMK,PPP3CB,FRA10AC1,STK33,BDNF,CLP1,SCYL1,PPP1CA,GSTP1,CDK4,TBK1,PRKAB1,RAN,GSKIP,PPCDC,EFL1,WDR24,ARL2BP,TERF2IP,PAFAH1B1,INCA1,HEXIM1,GDPD1,RPS6KB1,PGS1,RPTOR,CHMP6,RIOK3,IMPACT,MOB3A,MAP2K7 | 2118 | 0.5289958 |
| GO:BP | GO:0060135 | maternal process involved in female pregnancy | 2 | APOL2,PPARD | 40 | 0.5296234 |
| GO:BP | GO:2000678 | negative regulation of transcription regulatory region DNA binding | 1 | SRI | 17 | 0.5301497 |
| GO:BP | GO:0043524 | negative regulation of neuron apoptotic process | 2 | BDNF,LIG4 | 123 | 0.5303656 |
| GO:BP | GO:1902532 | negative regulation of intracellular signal transduction | 2 | HDAC1,AIDA | 444 | 0.5303656 |
| GO:BP | GO:0010977 | negative regulation of neuron projection development | 3 | PAFAH1B1,BCL11A,DGUOK | 117 | 0.5311660 |
| GO:BP | GO:0060252 | positive regulation of glial cell proliferation | 1 | UFL1 | 14 | 0.5311660 |
| GO:BP | GO:0014911 | positive regulation of smooth muscle cell migration | 1 | RPS6KB1 | 32 | 0.5314152 |
| GO:BP | GO:0032787 | monocarboxylic acid metabolic process | 1 | LYPLA2 | 435 | 0.5333052 |
| GO:BP | GO:1901184 | regulation of ERBB signaling pathway | 2 | CHMP6,RAB7A | 59 | 0.5333709 |
| GO:BP | GO:0008033 | tRNA processing | 4 | CLP1,TRMT61B,METTL8,MTO1 | 132 | 0.5333709 |
| GO:BP | GO:0000413 | protein peptidyl-prolyl isomerization | 1 | RANBP2 | 24 | 0.5335275 |
| GO:BP | GO:0015874 | norepinephrine transport | 1 | ADRA2C | 10 | 0.5339050 |
| GO:BP | GO:0051402 | neuron apoptotic process | 3 | BDNF,DIABLO,LIG4 | 210 | 0.5342731 |
| GO:BP | GO:0008285 | negative regulation of cell population proliferation | 10 | LMNA,ADORA1,GSTP1,THAP12,AQP11,RAB3IP,ING1,PML,PAFAH1B1,INCA1 | 643 | 0.5343335 |
| GO:BP | GO:2001257 | regulation of cation channel activity | 1 | PPP3CB | 100 | 0.5343919 |
| GO:BP | GO:0001701 | in utero embryonic development | 9 | LIG4,NXN,NLE1,SLC39A3,SMG9,DHX35,SMARCB1,MYO18B,ACTL6A | 338 | 0.5369739 |
| GO:BP | GO:0046887 | positive regulation of hormone secretion | 1 | PPP3CB | 93 | 0.5369739 |
| GO:BP | GO:0097035 | regulation of membrane lipid distribution | 1 | TRIAP1 | 42 | 0.5372952 |
| GO:BP | GO:0050796 | regulation of insulin secretion | 5 | PPP3CB,EIPR1,PICK1,PPARD,SRI | 118 | 0.5377058 |
| GO:BP | GO:0090266 | regulation of mitotic cell cycle spindle assembly checkpoint | 1 | MAD1L1 | 18 | 0.5377901 |
| GO:BP | GO:0021549 | cerebellum development | 1 | CLP1 | 77 | 0.5377901 |
| GO:BP | GO:0001662 | behavioral fear response | 1 | RPS6KB1 | 30 | 0.5377901 |
| GO:BP | GO:1903504 | regulation of mitotic spindle checkpoint | 1 | MAD1L1 | 18 | 0.5377901 |
| GO:BP | GO:0090231 | regulation of spindle checkpoint | 1 | MAD1L1 | 18 | 0.5377901 |
| GO:BP | GO:0048015 | phosphatidylinositol-mediated signaling | 1 | RPS6KB1 | 30 | 0.5377901 |
| GO:BP | GO:0050779 | RNA destabilization | 1 | POLR2G | 95 | 0.5377901 |
| GO:BP | GO:1905709 | negative regulation of membrane permeability | 1 | BAK1 | 19 | 0.5377901 |
| GO:BP | GO:1903432 | regulation of TORC1 signaling | 1 | WDR24 | 50 | 0.5377901 |
| GO:BP | GO:0061014 | positive regulation of mRNA catabolic process | 1 | POLR2G | 96 | 0.5377901 |
| GO:BP | GO:0006643 | membrane lipid metabolic process | 1 | PIGC | 171 | 0.5378642 |
| GO:BP | GO:0007005 | mitochondrion organization | 3 | LMNA,BLOC1S2,ARFIP2 | 500 | 0.5378642 |
| GO:BP | GO:0071684 | organism emergence from protective structure | 1 | SMARCB1 | 22 | 0.5386399 |
| GO:BP | GO:0018107 | peptidyl-threonine phosphorylation | 2 | TBK1,RPTOR | 96 | 0.5386399 |
| GO:BP | GO:0001835 | blastocyst hatching | 1 | SMARCB1 | 22 | 0.5386399 |
| GO:BP | GO:0044057 | regulation of system process | 2 | LMNA,ADORA1 | 398 | 0.5386399 |
| GO:BP | GO:0051960 | regulation of nervous system development | 1 | HDAC1 | 355 | 0.5386399 |
| GO:BP | GO:0035188 | hatching | 1 | SMARCB1 | 22 | 0.5386399 |
| GO:BP | GO:0046824 | positive regulation of nucleocytoplasmic transport | 2 | RAN,RIOK2 | 53 | 0.5395027 |
| GO:BP | GO:2000641 | regulation of early endosome to late endosome transport | 1 | SNX12 | 18 | 0.5406292 |
| GO:BP | GO:0007219 | Notch signaling pathway | 1 | PSEN2 | 145 | 0.5406292 |
| GO:BP | GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process | 1 | PML | 48 | 0.5409555 |
| GO:BP | GO:0006611 | protein export from nucleus | 1 | RAN | 56 | 0.5411055 |
| GO:BP | GO:0006357 | regulation of transcription by RNA polymerase II | 13 | HDAC1,MED8,LMO4,VPS72,SUV39H2,ECD,PPP3CB,ANKRD1,ZNF195,ZNF408,KAT5,BRMS1,RBM14 | 1763 | 0.5411055 |
| GO:BP | GO:0042491 | inner ear auditory receptor cell differentiation | 1 | PAFAH1B1 | 28 | 0.5411055 |
| GO:BP | GO:0042306 | regulation of protein import into nucleus | 1 | RAN | 51 | 0.5411055 |
| GO:BP | GO:0045822 | negative regulation of heart contraction | 1 | SRI | 15 | 0.5431066 |
| GO:BP | GO:0002009 | morphogenesis of an epithelium | 7 | LMO4,PPP1CA,TTC8,PML,CLUAP1,PAFAH1B1,MKS1 | 415 | 0.5432363 |
| GO:BP | GO:0008016 | regulation of heart contraction | 1 | ADORA1 | 171 | 0.5432363 |
| GO:BP | GO:0010628 | positive regulation of gene expression | 4 | HDAC1,VPS72,LMNA,JMJD4 | 796 | 0.5432363 |
| GO:BP | GO:0002381 | immunoglobulin production involved in immunoglobulin-mediated immune response | 1 | LIG4 | 42 | 0.5432363 |
| GO:BP | GO:0071548 | response to dexamethasone | 1 | RPS6KB1 | 34 | 0.5432363 |
| GO:BP | GO:0035264 | multicellular organism growth | 2 | CDK4,TTC8 | 125 | 0.5432363 |
| GO:BP | GO:0008334 | histone mRNA metabolic process | 1 | TENT2 | 20 | 0.5432363 |
| GO:BP | GO:0030182 | neuron differentiation | 3 | LYPLA2,HDAC1,LMO4 | 1057 | 0.5432363 |
| GO:BP | GO:0002209 | behavioral defense response | 1 | RPS6KB1 | 31 | 0.5432363 |
| GO:BP | GO:0006641 | triglyceride metabolic process | 1 | KAT5 | 67 | 0.5432363 |
| GO:BP | GO:0051094 | positive regulation of developmental process | 2 | PITHD1,HDAC1 | 956 | 0.5432363 |
| GO:BP | GO:0032496 | response to lipopolysaccharide | 3 | ANKRD1,GSTP1,CDK4 | 184 | 0.5432363 |
| GO:BP | GO:0051963 | regulation of synapse assembly | 1 | BDNF | 81 | 0.5432363 |
| GO:BP | GO:0006862 | nucleotide transport | 1 | SLC35B1 | 31 | 0.5432363 |
| GO:BP | GO:1904358 | positive regulation of telomere maintenance via telomere lengthening | 1 | MAP2K7 | 33 | 0.5432363 |
| GO:BP | GO:0045730 | respiratory burst | 1 | RAC3 | 22 | 0.5433063 |
| GO:BP | GO:0044248 | cellular catabolic process | 2 | LYPLA2,STX12 | 1241 | 0.5433063 |
| GO:BP | GO:0050687 | negative regulation of defense response to virus | 2 | RIOK3,ZDHHC12 | 40 | 0.5435130 |
| GO:BP | GO:0070085 | glycosylation | 2 | COG2,AQP11 | 198 | 0.5439732 |
| GO:BP | GO:0120178 | steroid hormone biosynthetic process | 1 | HSD17B1 | 29 | 0.5445547 |
| GO:BP | GO:0050931 | pigment cell differentiation | 1 | AP1M1 | 26 | 0.5445547 |
| GO:BP | GO:0043094 | cellular metabolic compound salvage | 1 | DGUOK | 25 | 0.5445948 |
| GO:BP | GO:0019318 | hexose metabolic process | 1 | DUSP12 | 187 | 0.5447855 |
| GO:BP | GO:0035295 | tube development | 1 | CPLANE2 | 822 | 0.5450650 |
| GO:BP | GO:0070306 | lens fiber cell differentiation | 1 | FZR1 | 30 | 0.5454101 |
| GO:BP | GO:1900273 | positive regulation of long-term synaptic potentiation | 1 | PRKAR1B | 17 | 0.5454176 |
| GO:BP | GO:0002183 | cytoplasmic translational initiation | 1 | IMPACT | 37 | 0.5462925 |
| GO:BP | GO:0051453 | regulation of intracellular pH | 1 | AQP11 | 66 | 0.5464475 |
| GO:BP | GO:0070664 | negative regulation of leukocyte proliferation | 1 | GSTP1 | 51 | 0.5465158 |
| GO:BP | GO:0070242 | thymocyte apoptotic process | 1 | BAK1 | 18 | 0.5465285 |
| GO:BP | GO:0031325 | positive regulation of cellular metabolic process | 35 | PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,DUSP12,ADORA1,JMJD4,ECD,PPP3CB,ANKRD1,BLOC1S2,BDNF,POLR2G,KAT5,RBM14,GSTP1,MED17,ANKRD49,PAFAH1B2,TBK1,CRY1,PRKAB1,TRIAP1,GTF2F2,ING1,BRF1,TRIP4,PML,WDR24,ARL2BP,E2F4,ZFP90,TERF2IP | 2519 | 0.5466989 |
| GO:BP | GO:0061245 | establishment or maintenance of bipolar cell polarity | 1 | TTC8 | 49 | 0.5466989 |
| GO:BP | GO:0035088 | establishment or maintenance of apical/basal cell polarity | 1 | TTC8 | 49 | 0.5466989 |
| GO:BP | GO:0071786 | endoplasmic reticulum tubular network organization | 1 | REEP4 | 20 | 0.5466989 |
| GO:BP | GO:0001975 | response to amphetamine | 1 | RANBP2 | 21 | 0.5479263 |
| GO:BP | GO:0071218 | cellular response to misfolded protein | 1 | DNAJC18 | 23 | 0.5485209 |
| GO:BP | GO:0045582 | positive regulation of T cell differentiation | 3 | KAT5,SMARCB1,ACTL6A | 74 | 0.5490502 |
| GO:BP | GO:0032642 | regulation of chemokine production | 1 | GSTP1 | 47 | 0.5490502 |
| GO:BP | GO:0032602 | chemokine production | 1 | GSTP1 | 47 | 0.5490502 |
| GO:BP | GO:1904064 | positive regulation of cation transmembrane transport | 1 | PPP3CB | 97 | 0.5493097 |
| GO:BP | GO:0021795 | cerebral cortex cell migration | 1 | PAFAH1B1 | 37 | 0.5498360 |
| GO:BP | GO:0042181 | ketone biosynthetic process | 1 | HSD17B1 | 38 | 0.5498360 |
| GO:BP | GO:0090102 | cochlea development | 1 | PAFAH1B1 | 34 | 0.5498360 |
| GO:BP | GO:0120254 | olefinic compound metabolic process | 3 | GSTP1,HSD17B1,RDH13 | 84 | 0.5510880 |
| GO:BP | GO:0007612 | learning | 1 | PPP3CB | 114 | 0.5511274 |
| GO:BP | GO:0062125 | regulation of mitochondrial gene expression | 1 | METTL8 | 31 | 0.5529105 |
| GO:BP | GO:0007205 | protein kinase C-activating G protein-coupled receptor signaling pathway | 1 | PICK1 | 19 | 0.5529105 |
| GO:BP | GO:0019216 | regulation of lipid metabolic process | 3 | ADORA1,KAT5,CDK4 | 251 | 0.5529105 |
| GO:BP | GO:0002092 | positive regulation of receptor internalization | 1 | PICK1 | 21 | 0.5529105 |
| GO:BP | GO:0002831 | regulation of response to biotic stimulus | 7 | TRIM3,KAT5,RBM14,TBK1,PML,HEXIM1,RIOK3 | 321 | 0.5529105 |
| GO:BP | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle | 1 | RPTOR | 39 | 0.5529105 |
| GO:BP | GO:1901880 | negative regulation of protein depolymerization | 1 | NAV3 | 60 | 0.5532104 |
| GO:BP | GO:1901071 | glucosamine-containing compound metabolic process | 1 | GNPDA2 | 19 | 0.5532104 |
| GO:BP | GO:0045932 | negative regulation of muscle contraction | 1 | SRI | 17 | 0.5532104 |
| GO:BP | GO:1903523 | negative regulation of blood circulation | 1 | SRI | 16 | 0.5532104 |
| GO:BP | GO:0061013 | regulation of mRNA catabolic process | 3 | POLR2G,CASC3,EIF4A3 | 163 | 0.5539908 |
| GO:BP | GO:0007098 | centrosome cycle | 2 | RBM14,CHMP1A | 128 | 0.5540675 |
| GO:BP | GO:0046033 | AMP metabolic process | 1 | PAICS | 21 | 0.5541692 |
| GO:BP | GO:0006094 | gluconeogenesis | 2 | CRY1,RANBP2 | 70 | 0.5541751 |
| GO:BP | GO:0016447 | somatic recombination of immunoglobulin gene segments | 1 | LIG4 | 48 | 0.5552344 |
| GO:BP | GO:0005976 | polysaccharide metabolic process | 1 | PPP1CA | 81 | 0.5563617 |
| GO:BP | GO:0046856 | phosphatidylinositol dephosphorylation | 1 | SACM1L | 26 | 0.5574157 |
| GO:BP | GO:0030641 | regulation of cellular pH | 1 | AQP11 | 70 | 0.5581198 |
| GO:BP | GO:0048839 | inner ear development | 3 | TTC8,PAFAH1B1,MKS1 | 129 | 0.5581198 |
| GO:BP | GO:0022037 | metencephalon development | 1 | CLP1 | 83 | 0.5583284 |
| GO:BP | GO:0001824 | blastocyst development | 3 | NLE1,SMARCB1,ACTL6A | 94 | 0.5583284 |
| GO:BP | GO:0051099 | positive regulation of binding | 2 | BDNF,RAN | 149 | 0.5584822 |
| GO:BP | GO:0032006 | regulation of TOR signaling | 2 | WDR24,RPTOR | 101 | 0.5597377 |
| GO:BP | GO:0032007 | negative regulation of TOR signaling | 1 | WDR24 | 50 | 0.5597998 |
| GO:BP | GO:0045861 | negative regulation of proteolysis | 4 | AQP11,TRIAP1,PML,NLE1 | 204 | 0.5597998 |
| GO:BP | GO:0043299 | leukocyte degranulation | 1 | C12orf4 | 40 | 0.5605197 |
| GO:BP | GO:0003009 | skeletal muscle contraction | 1 | RPS6KB1 | 31 | 0.5605197 |
| GO:BP | GO:0033574 | response to testosterone | 1 | RPS6KB1 | 30 | 0.5605197 |
| GO:BP | GO:0031175 | neuron projection development | 5 | LYPLA2,LMO4,PPP3CB,BLOC1S2,BDNF | 773 | 0.5616103 |
| GO:BP | GO:0009719 | response to endogenous stimulus | 1 | AGTRAP | 1260 | 0.5630175 |
| GO:BP | GO:0046823 | negative regulation of nucleocytoplasmic transport | 1 | RAB23 | 21 | 0.5632097 |
| GO:BP | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 1 | RAC3 | 37 | 0.5632097 |
| GO:BP | GO:0008286 | insulin receptor signaling pathway | 2 | CDK4,RPS6KB1 | 102 | 0.5636932 |
| GO:BP | GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway | 1 | ADRA2C | 19 | 0.5636932 |
| GO:BP | GO:0051346 | negative regulation of hydrolase activity | 4 | TIPRL,TRIAP1,TTC8,NLE1 | 206 | 0.5643289 |
| GO:BP | GO:0035235 | ionotropic glutamate receptor signaling pathway | 1 | CPEB4 | 14 | 0.5650742 |
| GO:BP | GO:0033866 | nucleoside bisphosphate biosynthetic process | 1 | PPCDC | 50 | 0.5652668 |
| GO:BP | GO:0034030 | ribonucleoside bisphosphate biosynthetic process | 1 | PPCDC | 50 | 0.5652668 |
| GO:BP | GO:0034033 | purine nucleoside bisphosphate biosynthetic process | 1 | PPCDC | 50 | 0.5652668 |
| GO:BP | GO:0035459 | vesicle cargo loading | 1 | RAB1A | 27 | 0.5655812 |
| GO:BP | GO:0010799 | regulation of peptidyl-threonine phosphorylation | 1 | RPTOR | 35 | 0.5657214 |
| GO:BP | GO:0048522 | positive regulation of cellular process | 1 | WRAP73 | 4199 | 0.5657214 |
| GO:BP | GO:0140467 | integrated stress response signaling | 1 | IMPACT | 36 | 0.5657214 |
| GO:BP | GO:0071363 | cellular response to growth factor stimulus | 4 | HDAC1,ANKRD1,BDNF,BRMS1 | 549 | 0.5657214 |
| GO:BP | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus | 1 | MKRN2 | 17 | 0.5657937 |
| GO:BP | GO:0007276 | gamete generation | 1 | PITHD1 | 465 | 0.5660774 |
| GO:BP | GO:0072330 | monocarboxylic acid biosynthetic process | 3 | GSTP1,PRKAB1,OSBPL7 | 147 | 0.5660774 |
| GO:BP | GO:1904037 | positive regulation of epithelial cell apoptotic process | 1 | PIAS4 | 26 | 0.5668636 |
| GO:BP | GO:0060337 | type I interferon-mediated signaling pathway | 1 | TBK1 | 54 | 0.5679315 |
| GO:BP | GO:0023019 | signal transduction involved in regulation of gene expression | 1 | TRAF3IP2 | 14 | 0.5679315 |
| GO:BP | GO:0030100 | regulation of endocytosis | 2 | PPP3CB,ANKRD13D | 208 | 0.5684824 |
| GO:BP | GO:1902533 | positive regulation of intracellular signal transduction | 4 | ADORA1,PPP3CB,SYNPO2L,ANKRD1 | 707 | 0.5686242 |
| GO:BP | GO:0034976 | response to endoplasmic reticulum stress | 3 | AQP11,UBAC2,PML | 235 | 0.5687250 |
| GO:BP | GO:0016601 | Rac protein signal transduction | 1 | RAC3 | 41 | 0.5688234 |
| GO:BP | GO:0019319 | hexose biosynthetic process | 2 | CRY1,RANBP2 | 73 | 0.5689189 |
| GO:BP | GO:0010976 | positive regulation of neuron projection development | 3 | BDNF,PAFAH1B1,BCL11A | 133 | 0.5689864 |
| GO:BP | GO:0002237 | response to molecule of bacterial origin | 3 | ANKRD1,GSTP1,CDK4 | 193 | 0.5693159 |
| GO:BP | GO:2000026 | regulation of multicellular organismal development | 2 | PITHD1,HDAC1 | 993 | 0.5693159 |
| GO:BP | GO:0045055 | regulated exocytosis | 2 | PPP3CB,C12orf4 | 152 | 0.5693159 |
| GO:BP | GO:0014823 | response to activity | 1 | CRY1 | 50 | 0.5693159 |
| GO:BP | GO:0090068 | positive regulation of cell cycle process | 5 | KAT5,CDK4,RPTOR,MTA3,NSFL1C | 206 | 0.5693159 |
| GO:BP | GO:0010155 | regulation of proton transport | 1 | PPARD | 20 | 0.5693159 |
| GO:BP | GO:0070661 | leukocyte proliferation | 3 | PPP3CB,GSTP1,TBK1 | 188 | 0.5693159 |
| GO:BP | GO:0014912 | negative regulation of smooth muscle cell migration | 1 | PPARD | 22 | 0.5693159 |
| GO:BP | GO:0061077 | chaperone-mediated protein folding | 2 | DNAJC5,DNAJC18 | 63 | 0.5693159 |
| GO:BP | GO:0051788 | response to misfolded protein | 1 | DNAJC18 | 25 | 0.5693536 |
| GO:BP | GO:0071357 | cellular response to type I interferon | 1 | TBK1 | 55 | 0.5695952 |
| GO:BP | GO:0051131 | chaperone-mediated protein complex assembly | 1 | PSMG3 | 21 | 0.5695952 |
| GO:BP | GO:0031348 | negative regulation of defense response | 2 | ADORA1,GSTP1 | 182 | 0.5695952 |
| GO:BP | GO:0043603 | amide metabolic process | 17 | MRPL9,PSEN2,JMJD4,TRIM3,POLR2G,PPP1CA,BRF1,TRIP4,PML,EFL1,CASC3,RPS6KB1,EIF4A3,RPTOR,IMPACT,CERS4,FARSA | 1004 | 0.5700434 |
| GO:BP | GO:0006739 | NADP metabolic process | 1 | RPTOR | 40 | 0.5700434 |
| GO:BP | GO:0051383 | kinetochore organization | 1 | SMC2 | 21 | 0.5700434 |
| GO:BP | GO:0051602 | response to electrical stimulus | 1 | RPS6KB1 | 29 | 0.5706374 |
| GO:BP | GO:0048699 | generation of neurons | 3 | LYPLA2,HDAC1,LMO4 | 1119 | 0.5706374 |
| GO:BP | GO:0030262 | apoptotic nuclear changes | 1 | BLCAP | 22 | 0.5706374 |
| GO:BP | GO:1901575 | organic substance catabolic process | 3 | PITHD1,LYPLA2,RNF19B | 1729 | 0.5711547 |
| GO:BP | GO:0048872 | homeostasis of number of cells | 8 | PPP3CB,NLE1,RAC3,SLC39A3,ANKRD54,BAK1,UFL1,TRAF3IP2 | 236 | 0.5711547 |
| GO:BP | GO:0051651 | maintenance of location in cell | 3 | PML,ARL2BP,PAFAH1B1 | 177 | 0.5712343 |
| GO:BP | GO:0018210 | peptidyl-threonine modification | 2 | TBK1,RPTOR | 103 | 0.5718726 |
| GO:BP | GO:0071539 | protein localization to centrosome | 1 | NSFL1C | 31 | 0.5721542 |
| GO:BP | GO:0002685 | regulation of leukocyte migration | 1 | ADORA1 | 130 | 0.5721542 |
| GO:BP | GO:0048259 | regulation of receptor-mediated endocytosis | 1 | ANKRD13D | 86 | 0.5724081 |
| GO:BP | GO:0032355 | response to estradiol | 1 | KAT5 | 79 | 0.5724110 |
| GO:BP | GO:0062207 | regulation of pattern recognition receptor signaling pathway | 1 | TRIM3 | 94 | 0.5729189 |
| GO:BP | GO:0046037 | GMP metabolic process | 1 | PAICS | 23 | 0.5729189 |
| GO:BP | GO:0051783 | regulation of nuclear division | 1 | BUB3 | 115 | 0.5729918 |
| GO:BP | GO:0008206 | bile acid metabolic process | 1 | OSBPL7 | 35 | 0.5734266 |
| GO:BP | GO:0016445 | somatic diversification of immunoglobulins | 1 | LIG4 | 53 | 0.5739014 |
| GO:BP | GO:0005996 | monosaccharide metabolic process | 1 | DUSP12 | 212 | 0.5739014 |
| GO:BP | GO:1900016 | negative regulation of cytokine production involved in inflammatory response | 1 | MACIR | 14 | 0.5753596 |
| GO:BP | GO:0010605 | negative regulation of macromolecule metabolic process | 37 | PEX14,HDAC1,LMO4,VPS72,LMNA,TIPRL,AIDA,SUV39H2,ANKRD1,BUB3,TRIM3,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,GSTP1,AQP11,TBK1,NAV3,CRY1,TRIAP1,KMT5A,RAN,ING1,GSKIP,BAHD1,PML,ERCC4,ZFP90,TERF2IP,CHMP1A,NXN,INCA1,NLE1,CASC3,HEXIM1 | 2131 | 0.5753596 |
| GO:BP | GO:0140527 | reciprocal homologous recombination | 1 | ERCC4 | 35 | 0.5755042 |
| GO:BP | GO:0007131 | reciprocal meiotic recombination | 1 | ERCC4 | 35 | 0.5755042 |
| GO:BP | GO:0030516 | regulation of axon extension | 2 | PAFAH1B1,BCL11A | 82 | 0.5755997 |
| GO:BP | GO:1901861 | regulation of muscle tissue development | 1 | RPS6KB1 | 34 | 0.5755997 |
| GO:BP | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | 1 | CLDN12 | 10 | 0.5762808 |
| GO:BP | GO:0097484 | dendrite extension | 1 | BCL11A | 28 | 0.5766476 |
| GO:BP | GO:0031100 | animal organ regeneration | 2 | SRSF1,BAK1 | 47 | 0.5766476 |
| GO:BP | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2 | PML,BAK1 | 56 | 0.5766476 |
| GO:BP | GO:0006816 | calcium ion transport | 2 | PSEN2,PPP3CB | 275 | 0.5766476 |
| GO:BP | GO:0010950 | positive regulation of endopeptidase activity | 2 | DIABLO,PML | 122 | 0.5766476 |
| GO:BP | GO:0097061 | dendritic spine organization | 2 | PAFAH1B1,PICK1 | 65 | 0.5771145 |
| GO:BP | GO:0032479 | regulation of type I interferon production | 2 | TBK1,RIOK3 | 86 | 0.5771663 |
| GO:BP | GO:0044346 | fibroblast apoptotic process | 1 | BAK1 | 23 | 0.5771663 |
| GO:BP | GO:0030217 | T cell differentiation | 2 | PPP3CB,KAT5 | 189 | 0.5771663 |
| GO:BP | GO:1902894 | negative regulation of miRNA transcription | 1 | PPARD | 22 | 0.5771663 |
| GO:BP | GO:0051450 | myoblast proliferation | 1 | PPARD | 17 | 0.5771663 |
| GO:BP | GO:0032606 | type I interferon production | 2 | TBK1,RIOK3 | 86 | 0.5771663 |
| GO:BP | GO:0010951 | negative regulation of endopeptidase activity | 2 | TRIAP1,NLE1 | 93 | 0.5771663 |
| GO:BP | GO:0014910 | regulation of smooth muscle cell migration | 2 | RPS6KB1,PPARD | 57 | 0.5771663 |
| GO:BP | GO:0045648 | positive regulation of erythrocyte differentiation | 1 | ANKRD54 | 26 | 0.5771663 |
| GO:BP | GO:0046697 | decidualization | 1 | PPARD | 19 | 0.5771663 |
| GO:BP | GO:0014856 | skeletal muscle cell proliferation | 1 | PPARD | 17 | 0.5771663 |
| GO:BP | GO:0090200 | positive regulation of release of cytochrome c from mitochondria | 1 | BAK1 | 21 | 0.5771663 |
| GO:BP | GO:1905508 | protein localization to microtubule organizing center | 1 | NSFL1C | 32 | 0.5785158 |
| GO:BP | GO:0072080 | nephron tubule development | 1 | AQP11 | 74 | 0.5785158 |
| GO:BP | GO:0043507 | positive regulation of JUN kinase activity | 1 | MAP2K7 | 35 | 0.5785158 |
| GO:BP | GO:0050770 | regulation of axonogenesis | 3 | BDNF,PAFAH1B1,BCL11A | 139 | 0.5786345 |
| GO:BP | GO:0060047 | heart contraction | 1 | ADORA1 | 202 | 0.5790548 |
| GO:BP | GO:0001676 | long-chain fatty acid metabolic process | 1 | GSTP1 | 63 | 0.5790548 |
| GO:BP | GO:0009205 | purine ribonucleoside triphosphate metabolic process | 2 | RAN,EFL1 | 135 | 0.5790548 |
| GO:BP | GO:0039694 | viral RNA genome replication | 1 | SMARCB1 | 27 | 0.5790548 |
| GO:BP | GO:0045292 | mRNA cis splicing, via spliceosome | 1 | SDE2 | 26 | 0.5795201 |
| GO:BP | GO:0050678 | regulation of epithelial cell proliferation | 3 | SAAL1,AQP11,CDK4 | 268 | 0.5800112 |
| GO:BP | GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 1 | ADORA1 | 113 | 0.5801094 |
| GO:BP | GO:0006909 | phagocytosis | 1 | ADORA1 | 144 | 0.5801094 |
| GO:BP | GO:0006885 | regulation of pH | 1 | AQP11 | 74 | 0.5807278 |
| GO:BP | GO:0035315 | hair cell differentiation | 1 | PAFAH1B1 | 33 | 0.5811568 |
| GO:BP | GO:0009048 | dosage compensation by inactivation of X chromosome | 1 | PHF20 | 28 | 0.5811568 |
| GO:BP | GO:0060997 | dendritic spine morphogenesis | 1 | PAFAH1B1 | 47 | 0.5811568 |
| GO:BP | GO:1990830 | cellular response to leukemia inhibitory factor | 3 | PML,SRSF3,POLR1F | 86 | 0.5814313 |
| GO:BP | GO:0097107 | postsynaptic density assembly | 1 | ZDHHC12 | 15 | 0.5828590 |
| GO:BP | GO:0034767 | positive regulation of monoatomic ion transmembrane transport | 1 | PPP3CB | 112 | 0.5828590 |
| GO:BP | GO:0006813 | potassium ion transport | 1 | ADORA1 | 146 | 0.5840330 |
| GO:BP | GO:0048666 | neuron development | 6 | LYPLA2,LMO4,PPP3CB,BLOC1S2,BDNF,SCYL1 | 872 | 0.5849013 |
| GO:BP | GO:0043242 | negative regulation of protein-containing complex disassembly | 1 | NAV3 | 68 | 0.5849798 |
| GO:BP | GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 1 | BLCAP | 24 | 0.5852605 |
| GO:BP | GO:0030177 | positive regulation of Wnt signaling pathway | 2 | GSKIP,NLE1 | 119 | 0.5863303 |
| GO:BP | GO:0070536 | protein K63-linked deubiquitination | 1 | PSMD14 | 33 | 0.5865803 |
| GO:BP | GO:0014070 | response to organic cyclic compound | 12 | HDAC1,ADORA1,KAT5,CDK4,CRY1,RAN,SLC46A3,TRIP4,OSBPL7,RPS6KB1,EIF4A3,RIOK3 | 632 | 0.5868558 |
| GO:BP | GO:0034340 | response to type I interferon | 1 | TBK1 | 60 | 0.5868558 |
| GO:BP | GO:0002221 | pattern recognition receptor signaling pathway | 2 | TRIM3,TBK1 | 142 | 0.5871059 |
| GO:BP | GO:1990823 | response to leukemia inhibitory factor | 3 | PML,SRSF3,POLR1F | 87 | 0.5872580 |
| GO:BP | GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 1 | LIG4 | 55 | 0.5877846 |
| GO:BP | GO:0045662 | negative regulation of myoblast differentiation | 1 | PPARD | 20 | 0.5877846 |
| GO:BP | GO:0016444 | somatic cell DNA recombination | 1 | LIG4 | 55 | 0.5877846 |
| GO:BP | GO:0051707 | response to other organism | 1 | PLEKHM2 | 846 | 0.5878378 |
| GO:BP | GO:0043207 | response to external biotic stimulus | 1 | PLEKHM2 | 846 | 0.5881288 |
| GO:BP | GO:0009129 | pyrimidine nucleoside monophosphate metabolic process | 1 | UPRT | 18 | 0.5881288 |
| GO:BP | GO:0070848 | response to growth factor | 4 | HDAC1,ANKRD1,BDNF,BRMS1 | 571 | 0.5881288 |
| GO:BP | GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 1 | ADORA1 | 160 | 0.5881288 |
| GO:BP | GO:1901223 | negative regulation of non-canonical NF-kappaB signal transduction | 1 | MKRN2 | 22 | 0.5884563 |
| GO:BP | GO:0016051 | carbohydrate biosynthetic process | 2 | PPP1CA,CRY1 | 160 | 0.5888140 |
| GO:BP | GO:0090630 | activation of GTPase activity | 2 | RALGAPA1,SYDE1 | 93 | 0.5888140 |
| GO:BP | GO:0051147 | regulation of muscle cell differentiation | 1 | BDNF | 118 | 0.5892985 |
| GO:BP | GO:0006783 | heme biosynthetic process | 1 | SRRD | 29 | 0.5894508 |
| GO:BP | GO:1900542 | regulation of purine nucleotide metabolic process | 1 | RPTOR | 38 | 0.5905933 |
| GO:BP | GO:0050773 | regulation of dendrite development | 2 | PAFAH1B1,BCL11A | 82 | 0.5905933 |
| GO:BP | GO:0060998 | regulation of dendritic spine development | 1 | PAFAH1B1 | 51 | 0.5905933 |
| GO:BP | GO:0009967 | positive regulation of signal transduction | 17 | ADORA1,PPP3CB,SYNPO2L,ANKRD1,TRIM3,BDNF,RAD9A,PPP1CA,TBK1,GSKIP,PML,WDR24,TERF2IP,PAFAH1B1,INCA1,NLE1,HEXIM1 | 1115 | 0.5910345 |
| GO:BP | GO:2000772 | regulation of cellular senescence | 1 | FZR1 | 37 | 0.5916812 |
| GO:BP | GO:0034765 | regulation of monoatomic ion transmembrane transport | 2 | PSEN2,PPP3CB | 296 | 0.5924757 |
| GO:BP | GO:0003015 | heart process | 1 | ADORA1 | 213 | 0.5926545 |
| GO:BP | GO:0006629 | lipid metabolic process | 19 | LYPLA2,PIGC,ADORA1,IPMK,KAT5,GSTP1,PAFAH1B2,CDK4,GLTP,PRKAB1,CES2,PAFAH1B1,HSD17B1,OSBPL7,GDPD1,PGS1,RPTOR,PIAS4,CERS4 | 989 | 0.5926755 |
| GO:BP | GO:0006775 | fat-soluble vitamin metabolic process | 1 | PIAS4 | 21 | 0.5932991 |
| GO:BP | GO:0002706 | regulation of lymphocyte mediated immunity | 1 | PPP3CB | 90 | 0.5932991 |
| GO:BP | GO:0048518 | positive regulation of biological process | 1 | WRAP73 | 4568 | 0.5934630 |
| GO:BP | GO:0019082 | viral protein processing | 1 | SPCS1 | 31 | 0.5936443 |
| GO:BP | GO:0002703 | regulation of leukocyte mediated immunity | 2 | PPP3CB,C12orf4 | 123 | 0.5936508 |
| GO:BP | GO:0009607 | response to biotic stimulus | 1 | PLEKHM2 | 874 | 0.5945637 |
| GO:BP | GO:0035967 | cellular response to topologically incorrect protein | 3 | DNAJC18,BAK1,UFL1 | 103 | 0.5946328 |
| GO:BP | GO:0042462 | eye photoreceptor cell development | 1 | RDH13 | 19 | 0.5950329 |
| GO:BP | GO:0071385 | cellular response to glucocorticoid stimulus | 1 | RPS6KB1 | 37 | 0.5952850 |
| GO:BP | GO:0000902 | cell morphogenesis | 2 | LYPLA2,LMO4 | 739 | 0.5952850 |
| GO:BP | GO:1903522 | regulation of blood circulation | 1 | ADORA1 | 197 | 0.5953551 |
| GO:BP | GO:0045070 | positive regulation of viral genome replication | 1 | TMEM39A | 27 | 0.5953551 |
| GO:BP | GO:0006140 | regulation of nucleotide metabolic process | 1 | RPTOR | 38 | 0.5955585 |
| GO:BP | GO:0071470 | cellular response to osmotic stress | 1 | RPTOR | 41 | 0.5955585 |
| GO:BP | GO:0034308 | primary alcohol metabolic process | 2 | GDPD1,RDH13 | 60 | 0.5959043 |
| GO:BP | GO:0032148 | activation of protein kinase B activity | 1 | ADRA2C | 24 | 0.5959043 |
| GO:BP | GO:0009199 | ribonucleoside triphosphate metabolic process | 2 | RAN,EFL1 | 142 | 0.5959043 |
| GO:BP | GO:0009144 | purine nucleoside triphosphate metabolic process | 2 | RAN,EFL1 | 142 | 0.5959043 |
| GO:BP | GO:0034446 | substrate adhesion-dependent cell spreading | 2 | RAC3,RAB1A | 90 | 0.5959043 |
| GO:BP | GO:0007549 | dosage compensation | 1 | PHF20 | 30 | 0.5959334 |
| GO:BP | GO:0051235 | maintenance of location | 4 | CRY1,PML,ARL2BP,PAFAH1B1 | 263 | 0.5965333 |
| GO:BP | GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation | 1 | CHMP6 | 42 | 0.5965333 |
| GO:BP | GO:0019725 | cellular homeostasis | 5 | ADORA1,PPP3CB,KAT5,GSTP1,AQP11 | 583 | 0.5965333 |
| GO:BP | GO:0048609 | multicellular organismal reproductive process | 1 | PITHD1 | 538 | 0.5969624 |
| GO:BP | GO:0033617 | mitochondrial cytochrome c oxidase assembly | 1 | COX19 | 25 | 0.5974052 |
| GO:BP | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein | 1 | ARL2BP | 23 | 0.5979013 |
| GO:BP | GO:0046822 | regulation of nucleocytoplasmic transport | 3 | RAN,RIOK2,RAB23 | 98 | 0.5979013 |
| GO:BP | GO:0033628 | regulation of cell adhesion mediated by integrin | 1 | RAC3 | 36 | 0.5979013 |
| GO:BP | GO:0008347 | glial cell migration | 1 | PAFAH1B1 | 48 | 0.5982773 |
| GO:BP | GO:0031122 | cytoplasmic microtubule organization | 1 | PAFAH1B1 | 58 | 0.5982773 |
| GO:BP | GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 1 | PPP3CB | 104 | 0.5993568 |
| GO:BP | GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 1 | MKS1 | 51 | 0.5994635 |
| GO:BP | GO:0019722 | calcium-mediated signaling | 1 | PPP3CB | 118 | 0.6013004 |
| GO:BP | GO:0008643 | carbohydrate transport | 4 | AQP11,RPS6KB1,PPARD,MFSD4B | 115 | 0.6018144 |
| GO:BP | GO:0035825 | homologous recombination | 1 | ERCC4 | 42 | 0.6021250 |
| GO:BP | GO:0042147 | retrograde transport, endosome to Golgi | 3 | EIPR1,RAB7A,SNX12 | 90 | 0.6021250 |
| GO:BP | GO:0002275 | myeloid cell activation involved in immune response | 1 | C12orf4 | 47 | 0.6021250 |
| GO:BP | GO:0046578 | regulation of Ras protein signal transduction | 1 | SYNPO2L | 156 | 0.6021250 |
| GO:BP | GO:0006402 | mRNA catabolic process | 7 | POLR2G,CASC3,EIF4A3,SMG9,TENT2,TRAF3IP2,GSPT2 | 218 | 0.6021250 |
| GO:BP | GO:0042177 | negative regulation of protein catabolic process | 1 | AQP11 | 100 | 0.6021250 |
| GO:BP | GO:0031110 | regulation of microtubule polymerization or depolymerization | 1 | NAV3 | 81 | 0.6021250 |
| GO:BP | GO:1901879 | regulation of protein depolymerization | 1 | NAV3 | 74 | 0.6021250 |
| GO:BP | GO:0035065 | regulation of histone acetylation | 1 | CTBP1 | 29 | 0.6021667 |
| GO:BP | GO:0046364 | monosaccharide biosynthetic process | 2 | CRY1,RANBP2 | 82 | 0.6025776 |
| GO:BP | GO:0016242 | negative regulation of macroautophagy | 1 | TMEM39A | 31 | 0.6025776 |
| GO:BP | GO:0006911 | phagocytosis, engulfment | 1 | RAC3 | 30 | 0.6031108 |
| GO:BP | GO:0071310 | cellular response to organic substance | 1 | AGTRAP | 1389 | 0.6037091 |
| GO:BP | GO:0086064 | cell communication by electrical coupling involved in cardiac conduction | 1 | SRI | 26 | 0.6045998 |
| GO:BP | GO:0033137 | negative regulation of peptidyl-serine phosphorylation | 1 | BAK1 | 25 | 0.6045998 |
| GO:BP | GO:0018230 | peptidyl-L-cysteine S-palmitoylation | 1 | ZDHHC12 | 21 | 0.6045998 |
| GO:BP | GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 1 | BAK1 | 25 | 0.6045998 |
| GO:BP | GO:0018231 | peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine | 1 | ZDHHC12 | 21 | 0.6045998 |
| GO:BP | GO:0007423 | sensory organ development | 1 | HDAC1 | 395 | 0.6046531 |
| GO:BP | GO:0019079 | viral genome replication | 3 | SMARCB1,TMEM39A,CTBP1 | 104 | 0.6047933 |
| GO:BP | GO:0045621 | positive regulation of lymphocyte differentiation | 1 | KAT5 | 86 | 0.6057990 |
| GO:BP | GO:0023061 | signal release | 2 | ADORA1,PPP3CB | 328 | 0.6066409 |
| GO:BP | GO:0061180 | mammary gland epithelium development | 1 | PML | 56 | 0.6070658 |
| GO:BP | GO:1903313 | positive regulation of mRNA metabolic process | 1 | POLR2G | 121 | 0.6074534 |
| GO:BP | GO:0002200 | somatic diversification of immune receptors | 1 | LIG4 | 61 | 0.6074534 |
| GO:BP | GO:0050777 | negative regulation of immune response | 1 | PPP3CB | 118 | 0.6074534 |
| GO:BP | GO:0002683 | negative regulation of immune system process | 2 | ADORA1,PPP3CB | 304 | 0.6084436 |
| GO:BP | GO:0010952 | positive regulation of peptidase activity | 2 | DIABLO,PML | 135 | 0.6104553 |
| GO:BP | GO:0009220 | pyrimidine ribonucleotide biosynthetic process | 1 | UPRT | 19 | 0.6104553 |
| GO:BP | GO:0045943 | positive regulation of transcription by RNA polymerase I | 1 | SMARCB1 | 34 | 0.6104553 |
| GO:BP | GO:0003018 | vascular process in circulatory system | 1 | ADORA1 | 198 | 0.6104553 |
| GO:BP | GO:0019915 | lipid storage | 1 | CRY1 | 68 | 0.6108085 |
| GO:BP | GO:1904659 | glucose transmembrane transport | 3 | RPS6KB1,PPARD,MFSD4B | 84 | 0.6108085 |
| GO:BP | GO:0030097 | hemopoiesis | 1 | PITHD1 | 650 | 0.6108085 |
| GO:BP | GO:0006110 | regulation of glycolytic process | 1 | RPTOR | 43 | 0.6108085 |
| GO:BP | GO:0022029 | telencephalon cell migration | 1 | PAFAH1B1 | 44 | 0.6113814 |
| GO:BP | GO:0007399 | nervous system development | 3 | CPLANE2,LYPLA2,HDAC1 | 1882 | 0.6113814 |
| GO:BP | GO:0032504 | multicellular organism reproduction | 1 | PITHD1 | 558 | 0.6116303 |
| GO:BP | GO:0032370 | positive regulation of lipid transport | 1 | TRIAP1 | 57 | 0.6117484 |
| GO:BP | GO:0009395 | phospholipid catabolic process | 1 | GDPD1 | 37 | 0.6127147 |
| GO:BP | GO:0071875 | adrenergic receptor signaling pathway | 1 | ADRA2C | 24 | 0.6128242 |
| GO:BP | GO:0009394 | 2’-deoxyribonucleotide metabolic process | 1 | DGUOK | 34 | 0.6130047 |
| GO:BP | GO:0045595 | regulation of cell differentiation | 2 | PITHD1,HDAC1 | 1118 | 0.6132005 |
| GO:BP | GO:0032273 | positive regulation of protein polymerization | 1 | NAV3 | 75 | 0.6145552 |
| GO:BP | GO:0050804 | modulation of chemical synaptic transmission | 2 | ADORA1,PPP3CB | 343 | 0.6145552 |
| GO:BP | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity | 1 | SRI | 23 | 0.6150980 |
| GO:BP | GO:0099177 | regulation of trans-synaptic signaling | 2 | ADORA1,PPP3CB | 344 | 0.6155326 |
| GO:BP | GO:0035176 | social behavior | 1 | RPTOR | 34 | 0.6160080 |
| GO:BP | GO:0048814 | regulation of dendrite morphogenesis | 1 | PAFAH1B1 | 53 | 0.6160080 |
| GO:BP | GO:0098739 | import across plasma membrane | 1 | PPP3CB | 130 | 0.6160535 |
| GO:BP | GO:1901617 | organic hydroxy compound biosynthetic process | 3 | IPMK,HSD17B1,OSBPL7 | 174 | 0.6162023 |
| GO:BP | GO:0014909 | smooth muscle cell migration | 2 | RPS6KB1,PPARD | 64 | 0.6171973 |
| GO:BP | GO:0097553 | calcium ion transmembrane import into cytosol | 1 | PPP3CB | 125 | 0.6176615 |
| GO:BP | GO:0002758 | innate immune response-activating signaling pathway | 2 | TRIM3,TBK1 | 149 | 0.6180237 |
| GO:BP | GO:1903829 | positive regulation of protein localization | 2 | PPP3CB,ANKRD1 | 392 | 0.6193668 |
| GO:BP | GO:0099054 | presynapse assembly | 1 | LRFN3 | 37 | 0.6193668 |
| GO:BP | GO:0010558 | negative regulation of macromolecule biosynthetic process | 1 | PEX14 | 1668 | 0.6193668 |
| GO:BP | GO:0006897 | endocytosis | 4 | ADORA1,PPP3CB,AP2A2,ANKRD13D | 525 | 0.6193668 |
| GO:BP | GO:0019692 | deoxyribose phosphate metabolic process | 1 | DGUOK | 35 | 0.6193668 |
| GO:BP | GO:0090175 | regulation of establishment of planar polarity | 1 | MKS1 | 54 | 0.6193668 |
| GO:BP | GO:0009161 | ribonucleoside monophosphate metabolic process | 2 | PAICS,UPRT | 51 | 0.6193668 |
| GO:BP | GO:0046324 | regulation of glucose import | 1 | RPS6KB1 | 42 | 0.6193668 |
| GO:BP | GO:0009262 | deoxyribonucleotide metabolic process | 1 | DGUOK | 35 | 0.6193668 |
| GO:BP | GO:0002819 | regulation of adaptive immune response | 1 | PPP3CB | 113 | 0.6196196 |
| GO:BP | GO:0090276 | regulation of peptide hormone secretion | 1 | PPP3CB | 134 | 0.6196196 |
| GO:BP | GO:0048066 | developmental pigmentation | 1 | AP1M1 | 36 | 0.6203854 |
| GO:BP | GO:0043583 | ear development | 3 | TTC8,PAFAH1B1,MKS1 | 150 | 0.6205069 |
| GO:BP | GO:0006839 | mitochondrial transport | 1 | BLOC1S2 | 172 | 0.6223527 |
| GO:BP | GO:0043933 | protein-containing complex organization | 12 | PEX14,HDAC1,TRAPPC3,MED8,LMO4,LIX1L,VPS72,LMNA,AIDA,JMJD4,CCSAP,SUV39H2 | 1974 | 0.6224080 |
| GO:BP | GO:0030073 | insulin secretion | 1 | PPP3CB | 143 | 0.6224080 |
| GO:BP | GO:0051085 | chaperone cofactor-dependent protein refolding | 1 | DNAJC18 | 30 | 0.6224080 |
| GO:BP | GO:0050886 | endocrine process | 1 | CRY1 | 56 | 0.6224080 |
| GO:BP | GO:0003006 | developmental process involved in reproduction | 1 | PITHD1 | 603 | 0.6224080 |
| GO:BP | GO:0051241 | negative regulation of multicellular organismal process | 3 | HDAC1,LMNA,ADORA1 | 743 | 0.6233008 |
| GO:BP | GO:0106027 | neuron projection organization | 2 | PAFAH1B1,PICK1 | 74 | 0.6233530 |
| GO:BP | GO:0016482 | cytosolic transport | 5 | MON2,EIPR1,RAB7A,RAB14,SNX12 | 167 | 0.6235161 |
| GO:BP | GO:0050881 | musculoskeletal movement | 1 | RPS6KB1 | 41 | 0.6235161 |
| GO:BP | GO:0021885 | forebrain cell migration | 1 | PAFAH1B1 | 46 | 0.6235161 |
| GO:BP | GO:0043408 | regulation of MAPK cascade | 2 | ADORA1,AIDA | 473 | 0.6237285 |
| GO:BP | GO:0008645 | hexose transmembrane transport | 3 | RPS6KB1,PPARD,MFSD4B | 87 | 0.6238782 |
| GO:BP | GO:0072009 | nephron epithelium development | 1 | AQP11 | 87 | 0.6242978 |
| GO:BP | GO:0031327 | negative regulation of cellular biosynthetic process | 1 | PEX14 | 1707 | 0.6243296 |
| GO:BP | GO:0051703 | biological process involved in intraspecies interaction between organisms | 1 | RPTOR | 34 | 0.6253904 |
| GO:BP | GO:0009636 | response to toxic substance | 3 | GSTP1,NXN,RPS6KB1 | 158 | 0.6254926 |
| GO:BP | GO:1901224 | positive regulation of non-canonical NF-kappaB signal transduction | 1 | TERF2IP | 42 | 0.6256741 |
| GO:BP | GO:0009890 | negative regulation of biosynthetic process | 1 | PEX14 | 1720 | 0.6259743 |
| GO:BP | GO:0006952 | defense response | 1 | PLEKHM2 | 970 | 0.6284731 |
| GO:BP | GO:0050879 | multicellular organismal movement | 1 | RPS6KB1 | 41 | 0.6290653 |
| GO:BP | GO:0043467 | regulation of generation of precursor metabolites and energy | 2 | PPP1CA,RPTOR | 119 | 0.6306927 |
| GO:BP | GO:0010507 | negative regulation of autophagy | 2 | RPTOR,TMEM39A | 75 | 0.6306927 |
| GO:BP | GO:0062012 | regulation of small molecule metabolic process | 1 | DUSP12 | 248 | 0.6306927 |
| GO:BP | GO:1902808 | positive regulation of cell cycle G1/S phase transition | 1 | RPTOR | 49 | 0.6315015 |
| GO:BP | GO:0007155 | cell adhesion | 1 | CPLANE2 | 996 | 0.6315015 |
| GO:BP | GO:0007626 | locomotory behavior | 1 | PPP3CB | 139 | 0.6330299 |
| GO:BP | GO:0019226 | transmission of nerve impulse | 1 | PAFAH1B1 | 35 | 0.6332229 |
| GO:BP | GO:0140888 | interferon-mediated signaling pathway | 1 | TBK1 | 69 | 0.6359747 |
| GO:BP | GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 1 | SRI | 27 | 0.6361775 |
| GO:BP | GO:0042098 | T cell proliferation | 1 | PPP3CB | 120 | 0.6364082 |
| GO:BP | GO:0050896 | response to stimulus | 5 | PEX14,AGTRAP,PLEKHM2,CPLANE2,ARHGEF10L | 5725 | 0.6383857 |
| GO:BP | GO:0048638 | regulation of developmental growth | 4 | BDNF,CDK4,PAFAH1B1,RPS6KB1 | 255 | 0.6383857 |
| GO:BP | GO:0031960 | response to corticosteroid | 2 | RAN,RPS6KB1 | 93 | 0.6383857 |
| GO:BP | GO:0018108 | peptidyl-tyrosine phosphorylation | 1 | ADORA1 | 195 | 0.6390000 |
| GO:BP | GO:0045920 | negative regulation of exocytosis | 1 | RAB7A | 24 | 0.6390074 |
| GO:BP | GO:0010737 | protein kinase A signaling | 1 | SPATC1L | 23 | 0.6395854 |
| GO:BP | GO:0009141 | nucleoside triphosphate metabolic process | 2 | RAN,EFL1 | 158 | 0.6395854 |
| GO:BP | GO:0015749 | monosaccharide transmembrane transport | 3 | RPS6KB1,PPARD,MFSD4B | 88 | 0.6403215 |
| GO:BP | GO:0018212 | peptidyl-tyrosine modification | 1 | ADORA1 | 197 | 0.6408100 |
| GO:BP | GO:0002444 | myeloid leukocyte mediated immunity | 1 | C12orf4 | 58 | 0.6408100 |
| GO:BP | GO:0009112 | nucleobase metabolic process | 1 | PAICS | 28 | 0.6416555 |
| GO:BP | GO:0003008 | system process | 1 | AGTRAP | 1193 | 0.6433882 |
| GO:BP | GO:0030902 | hindbrain development | 1 | CLP1 | 114 | 0.6439147 |
| GO:BP | GO:0022604 | regulation of cell morphogenesis | 4 | ARAP1,PAFAH1B1,RAC3,BCL11A | 207 | 0.6441165 |
| GO:BP | GO:0099172 | presynapse organization | 1 | LRFN3 | 40 | 0.6441165 |
| GO:BP | GO:0048732 | gland development | 1 | LMO4 | 319 | 0.6448069 |
| GO:BP | GO:0018208 | peptidyl-proline modification | 1 | RANBP2 | 39 | 0.6448664 |
| GO:BP | GO:0006260 | DNA replication | 1 | SDE2 | 256 | 0.6448664 |
| GO:BP | GO:0045684 | positive regulation of epidermis development | 1 | PPARD | 20 | 0.6448664 |
| GO:BP | GO:0018105 | peptidyl-serine phosphorylation | 4 | BDNF,TBK1,RPS6KB1,RPTOR | 242 | 0.6451620 |
| GO:BP | GO:0045471 | response to ethanol | 3 | RPS6KB1,PSMD14,BAK1 | 72 | 0.6452280 |
| GO:BP | GO:0035510 | DNA dealkylation | 1 | ASCC2 | 28 | 0.6452280 |
| GO:BP | GO:0019953 | sexual reproduction | 1 | PITHD1 | 633 | 0.6456363 |
| GO:BP | GO:0030968 | endoplasmic reticulum unfolded protein response | 2 | BAK1,UFL1 | 70 | 0.6456363 |
| GO:BP | GO:0033077 | T cell differentiation in thymus | 1 | LIG4 | 57 | 0.6461140 |
| GO:BP | GO:1990806 | ligand-gated ion channel signaling pathway | 1 | CPEB4 | 20 | 0.6461140 |
| GO:BP | GO:0022008 | neurogenesis | 3 | LYPLA2,HDAC1,LMO4 | 1295 | 0.6461140 |
| GO:BP | GO:0008360 | regulation of cell shape | 2 | ARAP1,RAC3 | 115 | 0.6461140 |
| GO:BP | GO:0042509 | regulation of tyrosine phosphorylation of STAT protein | 1 | ARL2BP | 34 | 0.6463932 |
| GO:BP | GO:0008535 | respiratory chain complex IV assembly | 1 | COX19 | 29 | 0.6468806 |
| GO:BP | GO:0042446 | hormone biosynthetic process | 1 | HSD17B1 | 39 | 0.6469028 |
| GO:BP | GO:0030517 | negative regulation of axon extension | 1 | BCL11A | 41 | 0.6469028 |
| GO:BP | GO:0043331 | response to dsRNA | 1 | RIOK3 | 33 | 0.6469028 |
| GO:BP | GO:0015844 | monoamine transport | 2 | PICK1,ADRA2C | 48 | 0.6472559 |
| GO:BP | GO:1903018 | regulation of glycoprotein metabolic process | 1 | RAB1A | 35 | 0.6484291 |
| GO:BP | GO:0002312 | B cell activation involved in immune response | 1 | LIG4 | 58 | 0.6493289 |
| GO:BP | GO:0001756 | somitogenesis | 1 | NLE1 | 48 | 0.6500764 |
| GO:BP | GO:0061512 | protein localization to cilium | 1 | RABEP1 | 62 | 0.6501876 |
| GO:BP | GO:0099024 | plasma membrane invagination | 1 | RAC3 | 39 | 0.6505574 |
| GO:BP | GO:0051223 | regulation of protein transport | 2 | PPP3CB,ANKRD1 | 403 | 0.6507910 |
| GO:BP | GO:0009653 | anatomical structure morphogenesis | 3 | CPLANE2,LYPLA2,HDAC1 | 1952 | 0.6513855 |
| GO:BP | GO:0060255 | regulation of macromolecule metabolic process | 103 | PEX14,PITHD1,HDAC1,RNF19B,MED8,LMO4,VPS72,LMNA,TIPRL,ADORA1,AIDA,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,BUB3,ZNF195,TRIM3,BDNF,ZNF408,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,GSTP1,ARAP1,EMSY,AQP11,MED17,ANKRD49,MLF2,CDK4,TBK1,NAV3,CRY1,PRKAB1,TRIAP1,DIABLO,KMT5A,RAN,ZNF605,GTF2F2,ING1,GSKIP,BRF1,BAHD1,TRIP4,PML,WDR24,ERCC4,ARL2BP,E2F4,ZFP90,TERF2IP,CHMP1A,NXN,INCA1,ZNF287,NLE1,PEX12,CASC3,HEXIM1,OSBPL7,SPOP,SRSF1,RPS6KB1,INTS2,EIF4A3,RPTOR,CHMP6,RIOK3,IMPACT,MIER2,MOB3A,FZR1,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,SMG9,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,RAB1A,ZNF638 | 4597 | 0.6513855 |
| GO:BP | GO:0048523 | negative regulation of cellular process | 30 | PEX14,HDAC1,LMO4,VPS72,LMNA,TIPRL,ADORA1,AIDA,SDE2,PSEN2,SUV39H2,HERC4,PPP3CB,ANKRD1,BUB3,TRIM3,STK33,BDNF,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,ANKRD13D,RAD9A,GSTP1,ARAP1,THAP12,AQP11 | 3772 | 0.6521163 |
| GO:BP | GO:0043523 | regulation of neuron apoptotic process | 5 | BDNF,LIG4,MAP2K7,DNAJC5,CPEB4 | 171 | 0.6523429 |
| GO:BP | GO:0070613 | regulation of protein processing | 2 | IFT52,SNX12 | 48 | 0.6523811 |
| GO:BP | GO:0009612 | response to mechanical stimulus | 1 | ANKRD1 | 155 | 0.6523811 |
| GO:BP | GO:0062013 | positive regulation of small molecule metabolic process | 2 | CRY1,RPTOR | 107 | 0.6530812 |
| GO:BP | GO:0007610 | behavior | 3 | ADORA1,PPP3CB,BDNF | 438 | 0.6535841 |
| GO:BP | GO:0030072 | peptide hormone secretion | 6 | PPP3CB,EIPR1,RAB1A,PICK1,PPARD,SRI | 168 | 0.6538608 |
| GO:BP | GO:2000377 | regulation of reactive oxygen species metabolic process | 1 | GSTP1 | 107 | 0.6538970 |
| GO:BP | GO:2000463 | positive regulation of excitatory postsynaptic potential | 1 | PRKAR1B | 29 | 0.6551853 |
| GO:BP | GO:0006874 | intracellular calcium ion homeostasis | 1 | ADORA1 | 208 | 0.6558027 |
| GO:BP | GO:0009225 | nucleotide-sugar metabolic process | 1 | GNPDA2 | 36 | 0.6559509 |
| GO:BP | GO:0071241 | cellular response to inorganic substance | 3 | LIG4,HSD17B1,EIF4A3 | 165 | 0.6566020 |
| GO:BP | GO:0044255 | cellular lipid metabolic process | 1 | LYPLA2 | 736 | 0.6566020 |
| GO:BP | GO:0050680 | negative regulation of epithelial cell proliferation | 1 | AQP11 | 107 | 0.6566020 |
| GO:BP | GO:0014075 | response to amine | 1 | RANBP2 | 34 | 0.6566020 |
| GO:BP | GO:0009895 | negative regulation of catabolic process | 9 | ADORA1,AQP11,PML,RPTOR,TMEM39A,TENT2,TRAF3IP2,PHF20L1,SNX12 | 287 | 0.6566020 |
| GO:BP | GO:0071168 | protein localization to chromatin | 1 | PIAS4 | 42 | 0.6566020 |
| GO:BP | GO:0030855 | epithelial cell differentiation | 1 | HDAC1 | 437 | 0.6566020 |
| GO:BP | GO:0007260 | tyrosine phosphorylation of STAT protein | 1 | ARL2BP | 36 | 0.6569179 |
| GO:BP | GO:0042273 | ribosomal large subunit biogenesis | 1 | NLE1 | 70 | 0.6575399 |
| GO:BP | GO:1901564 | organonitrogen compound metabolic process | 17 | ICMT,CPLANE2,PITHD1,LYPLA2,HDAC1,RNF19B,MED8,VPS72,MRPL9,DUSP12,TIPRL,PIGC,ADORA1,AIDA,SDE2,PSEN2,JMJD4 | 4921 | 0.6575399 |
| GO:BP | GO:0010817 | regulation of hormone levels | 2 | ADORA1,PPP3CB | 336 | 0.6576120 |
| GO:BP | GO:0098698 | postsynaptic specialization assembly | 1 | ZDHHC12 | 22 | 0.6576616 |
| GO:BP | GO:0120162 | positive regulation of cold-induced thermogenesis | 1 | PRKAB1 | 72 | 0.6576616 |
| GO:BP | GO:0009892 | negative regulation of metabolic process | 38 | PEX14,HDAC1,LMO4,VPS72,LMNA,TIPRL,ADORA1,AIDA,SUV39H2,ANKRD1,BUB3,TRIM3,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,GSTP1,AQP11,TBK1,NAV3,CRY1,TRIAP1,KMT5A,RAN,ING1,GSKIP,BAHD1,PML,ERCC4,ZFP90,TERF2IP,CHMP1A,NXN,INCA1,NLE1,CASC3,HEXIM1 | 2297 | 0.6576616 |
| GO:BP | GO:0043484 | regulation of RNA splicing | 3 | SRSF1,HNRNPLL,ZNF638 | 163 | 0.6576616 |
| GO:BP | GO:0006955 | immune response | 1 | PLEKHM2 | 915 | 0.6584029 |
| GO:BP | GO:0046839 | phospholipid dephosphorylation | 1 | SACM1L | 36 | 0.6586461 |
| GO:BP | GO:1900024 | regulation of substrate adhesion-dependent cell spreading | 1 | RAC3 | 54 | 0.6586697 |
| GO:BP | GO:0038093 | Fc receptor signaling pathway | 1 | MAP2K7 | 36 | 0.6589377 |
| GO:BP | GO:0034764 | positive regulation of transmembrane transport | 1 | PPP3CB | 155 | 0.6612739 |
| GO:BP | GO:0090407 | organophosphate biosynthetic process | 2 | PIGC,IPMK | 506 | 0.6626571 |
| GO:BP | GO:0006513 | protein monoubiquitination | 1 | PEX12 | 71 | 0.6640820 |
| GO:BP | GO:0062014 | negative regulation of small molecule metabolic process | 1 | CRY1 | 75 | 0.6643344 |
| GO:BP | GO:0007420 | brain development | 1 | HDAC1 | 545 | 0.6649265 |
| GO:BP | GO:0023051 | regulation of signaling | 2 | CPLANE2,ARHGEF10L | 2559 | 0.6649265 |
| GO:BP | GO:0050776 | regulation of immune response | 6 | PPP3CB,TRIM3,KAT5,RBM14,C12orf4,TBK1 | 513 | 0.6649265 |
| GO:BP | GO:1903146 | regulation of autophagy of mitochondrion | 1 | PARL | 37 | 0.6655036 |
| GO:BP | GO:1902914 | regulation of protein polyubiquitination | 1 | UBE2V2 | 25 | 0.6658365 |
| GO:BP | GO:0051084 | ‘de novo’ post-translational protein folding | 1 | DNAJC18 | 35 | 0.6658365 |
| GO:BP | GO:0042572 | retinol metabolic process | 1 | RDH13 | 23 | 0.6658365 |
| GO:BP | GO:0010646 | regulation of cell communication | 2 | CPLANE2,ARHGEF10L | 2566 | 0.6658803 |
| GO:BP | GO:1900076 | regulation of cellular response to insulin stimulus | 1 | RPS6KB1 | 55 | 0.6666209 |
| GO:BP | GO:0008593 | regulation of Notch signaling pathway | 2 | SLC35C2,NEPRO | 78 | 0.6681850 |
| GO:BP | GO:2000628 | regulation of miRNA metabolic process | 2 | TENT2,PPARD | 69 | 0.6682563 |
| GO:BP | GO:0048468 | cell development | 3 | PITHD1,LYPLA2,HDAC1 | 1947 | 0.6685503 |
| GO:BP | GO:0032965 | regulation of collagen biosynthetic process | 1 | PPARD | 27 | 0.6695841 |
| GO:BP | GO:0001893 | maternal placenta development | 1 | PPARD | 28 | 0.6695841 |
| GO:BP | GO:0048645 | animal organ formation | 1 | MKS1 | 50 | 0.6702908 |
| GO:BP | GO:0043488 | regulation of mRNA stability | 1 | POLR2G | 149 | 0.6711915 |
| GO:BP | GO:0033993 | response to lipid | 8 | HDAC1,ANKRD1,KAT5,GSTP1,CDK4,CRY1,RAN,TRIP4 | 593 | 0.6713135 |
| GO:BP | GO:0070201 | regulation of establishment of protein localization | 2 | PPP3CB,ANKRD1 | 427 | 0.6718782 |
| GO:BP | GO:0090075 | relaxation of muscle | 1 | SRI | 27 | 0.6733827 |
| GO:BP | GO:0010837 | regulation of keratinocyte proliferation | 1 | IFT52 | 33 | 0.6733827 |
| GO:BP | GO:1903318 | negative regulation of protein maturation | 1 | SNX12 | 20 | 0.6733829 |
| GO:BP | GO:0010955 | negative regulation of protein processing | 1 | SNX12 | 20 | 0.6733829 |
| GO:BP | GO:0031324 | negative regulation of cellular metabolic process | 1 | PEX14 | 2069 | 0.6733829 |
| GO:BP | GO:0009798 | axis specification | 1 | TTC8 | 61 | 0.6736766 |
| GO:BP | GO:0023056 | positive regulation of signaling | 9 | ADORA1,PPP3CB,SYNPO2L,ANKRD1,TRIM3,BDNF,RAD9A,PPP1CA,ARAP1 | 1251 | 0.6744739 |
| GO:BP | GO:0002250 | adaptive immune response | 1 | RNF19B | 226 | 0.6744739 |
| GO:BP | GO:0002376 | immune system process | 2 | PLEKHM2,PITHD1 | 1483 | 0.6751574 |
| GO:BP | GO:0050794 | regulation of cellular process | 8 | WRAP73,PEX14,AGTRAP,PLEKHM2,CPLANE2,ARHGEF10L,ASAP3,PITHD1 | 7639 | 0.6751581 |
| GO:BP | GO:0044272 | sulfur compound biosynthetic process | 1 | GSTP1 | 123 | 0.6754532 |
| GO:BP | GO:0015909 | long-chain fatty acid transport | 1 | RPS6KB1 | 37 | 0.6754532 |
| GO:BP | GO:0065003 | protein-containing complex assembly | 1 | PEX14 | 1331 | 0.6756717 |
| GO:BP | GO:0033157 | regulation of intracellular protein transport | 2 | RAN,UBAC2 | 198 | 0.6756717 |
| GO:BP | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway | 1 | UFL1 | 28 | 0.6756717 |
| GO:BP | GO:0055074 | calcium ion homeostasis | 1 | ADORA1 | 221 | 0.6756920 |
| GO:BP | GO:0042461 | photoreceptor cell development | 1 | RDH13 | 30 | 0.6763730 |
| GO:BP | GO:0032103 | positive regulation of response to external stimulus | 3 | TRIM3,KAT5,RBM14 | 359 | 0.6767468 |
| GO:BP | GO:1903317 | regulation of protein maturation | 2 | IFT52,SNX12 | 51 | 0.6768110 |
| GO:BP | GO:0010762 | regulation of fibroblast migration | 1 | MACIR | 37 | 0.6768110 |
| GO:BP | GO:0046320 | regulation of fatty acid oxidation | 1 | PPARD | 30 | 0.6768110 |
| GO:BP | GO:0031667 | response to nutrient levels | 6 | KAT5,PRKAB1,WDR24,RPS6KB1,RPTOR,IMPACT | 355 | 0.6768715 |
| GO:BP | GO:0060411 | cardiac septum morphogenesis | 1 | MKS1 | 67 | 0.6772553 |
| GO:BP | GO:1905954 | positive regulation of lipid localization | 1 | TRIAP1 | 74 | 0.6772553 |
| GO:BP | GO:1903305 | regulation of regulated secretory pathway | 1 | C12orf4 | 86 | 0.6772553 |
| GO:BP | GO:0006304 | DNA modification | 2 | N6AMT1,ASCC2 | 86 | 0.6772957 |
| GO:BP | GO:0042088 | T-helper 1 type immune response | 1 | STAT4 | 27 | 0.6772957 |
| GO:BP | GO:0002861 | regulation of inflammatory response to antigenic stimulus | 1 | MKRN2 | 25 | 0.6780456 |
| GO:BP | GO:0048583 | regulation of response to stimulus | 21 | CPLANE2,ARHGEF10L,HDAC1,VPS72,LMNA,ADORA1,AIDA,HERC4,PPP3CB,SYNPO2L,ANKRD1,TRIM3,BDNF,KAT5,BRMS1,RBM14,RAD9A,PPP1CA,GSTP1,ARAP1,AQP11 | 2876 | 0.6788277 |
| GO:BP | GO:0051049 | regulation of transport | 1 | CPLANE2 | 1266 | 0.6788998 |
| GO:BP | GO:0050673 | epithelial cell proliferation | 3 | SAAL1,AQP11,CDK4 | 318 | 0.6788998 |
| GO:BP | GO:0018209 | peptidyl-serine modification | 4 | BDNF,TBK1,RPS6KB1,RPTOR | 254 | 0.6790133 |
| GO:BP | GO:0014808 | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 1 | SRI | 29 | 0.6790361 |
| GO:BP | GO:0045666 | positive regulation of neuron differentiation | 2 | IMPACT,ADRA2C | 63 | 0.6790361 |
| GO:BP | GO:0045646 | regulation of erythrocyte differentiation | 1 | ANKRD54 | 38 | 0.6790361 |
| GO:BP | GO:0010644 | cell communication by electrical coupling | 1 | SRI | 31 | 0.6790361 |
| GO:BP | GO:0002262 | myeloid cell homeostasis | 4 | ANKRD54,BAK1,UFL1,TRAF3IP2 | 142 | 0.6790361 |
| GO:BP | GO:0060688 | regulation of morphogenesis of a branching structure | 1 | BCL11A | 37 | 0.6790361 |
| GO:BP | GO:0006936 | muscle contraction | 1 | ADORA1 | 266 | 0.6790361 |
| GO:BP | GO:0050830 | defense response to Gram-positive bacterium | 1 | TBK1 | 37 | 0.6797409 |
| GO:BP | GO:0010324 | membrane invagination | 1 | RAC3 | 46 | 0.6799653 |
| GO:BP | GO:0051716 | cellular response to stimulus | 4 | PEX14,AGTRAP,CPLANE2,ARHGEF10L | 4930 | 0.6799653 |
| GO:BP | GO:0048593 | camera-type eye morphogenesis | 3 | TTC8,RDH13,BAK1 | 92 | 0.6799653 |
| GO:BP | GO:0051259 | protein complex oligomerization | 4 | AQP11,FARSA,TRMT61B,BCL11A | 190 | 0.6804755 |
| GO:BP | GO:0051445 | regulation of meiotic cell cycle | 1 | FZR1 | 45 | 0.6808097 |
| GO:BP | GO:0007405 | neuroblast proliferation | 1 | PAFAH1B1 | 56 | 0.6808097 |
| GO:BP | GO:0060322 | head development | 1 | HDAC1 | 587 | 0.6808097 |
| GO:BP | GO:0097305 | response to alcohol | 3 | CDK4,OSBPL7,RPS6KB1 | 160 | 0.6812429 |
| GO:BP | GO:1905898 | positive regulation of response to endoplasmic reticulum stress | 1 | BAK1 | 34 | 0.6814050 |
| GO:BP | GO:0000380 | alternative mRNA splicing, via spliceosome | 1 | SRSF1 | 63 | 0.6814050 |
| GO:BP | GO:1901222 | regulation of non-canonical NF-kappaB signal transduction | 2 | TERF2IP,MKRN2 | 67 | 0.6814050 |
| GO:BP | GO:0030001 | metal ion transport | 3 | ADORA1,PSEN2,PPP3CB | 569 | 0.6815545 |
| GO:BP | GO:0000165 | MAPK cascade | 2 | ADORA1,AIDA | 553 | 0.6828178 |
| GO:BP | GO:0009101 | glycoprotein biosynthetic process | 3 | AQP11,PHLDA1,COG7 | 252 | 0.6828178 |
| GO:BP | GO:0006694 | steroid biosynthetic process | 2 | HSD17B1,OSBPL7 | 124 | 0.6829807 |
| GO:BP | GO:0048705 | skeletal system morphogenesis | 3 | NLE1,EIF4A3,SLC39A3 | 155 | 0.6832299 |
| GO:BP | GO:0046942 | carboxylic acid transport | 1 | ADORA1 | 213 | 0.6841326 |
| GO:BP | GO:0015849 | organic acid transport | 1 | ADORA1 | 214 | 0.6852098 |
| GO:BP | GO:0014812 | muscle cell migration | 2 | RPS6KB1,PPARD | 75 | 0.6861114 |
| GO:BP | GO:0072073 | kidney epithelium development | 1 | AQP11 | 113 | 0.6862376 |
| GO:BP | GO:0016052 | carbohydrate catabolic process | 1 | PPP1CA | 125 | 0.6867084 |
| GO:BP | GO:1903514 | release of sequestered calcium ion into cytosol by endoplasmic reticulum | 1 | SRI | 29 | 0.6867084 |
| GO:BP | GO:0032868 | response to insulin | 2 | CDK4,CRY1 | 211 | 0.6874027 |
| GO:BP | GO:0035567 | non-canonical Wnt signaling pathway | 1 | MKS1 | 67 | 0.6875450 |
| GO:BP | GO:0001889 | liver development | 3 | SRSF1,SMARCB1,PTCD2 | 111 | 0.6879603 |
| GO:BP | GO:0060251 | regulation of glial cell proliferation | 1 | UFL1 | 26 | 0.6886742 |
| GO:BP | GO:0006040 | amino sugar metabolic process | 1 | GNPDA2 | 34 | 0.6886742 |
| GO:BP | GO:0043487 | regulation of RNA stability | 1 | POLR2G | 161 | 0.6886742 |
| GO:BP | GO:0032640 | tumor necrosis factor production | 1 | GSTP1 | 90 | 0.6886742 |
| GO:BP | GO:0032680 | regulation of tumor necrosis factor production | 1 | GSTP1 | 90 | 0.6886742 |
| GO:BP | GO:0006301 | postreplication repair | 1 | UBE2V2 | 33 | 0.6890802 |
| GO:BP | GO:0070227 | lymphocyte apoptotic process | 2 | BAK1,TRAF3IP2 | 58 | 0.6890802 |
| GO:BP | GO:0009167 | purine ribonucleoside monophosphate metabolic process | 1 | PAICS | 36 | 0.6896390 |
| GO:BP | GO:0043123 | positive regulation of canonical NF-kappaB signal transduction | 2 | TBK1,TERF2IP | 154 | 0.6900333 |
| GO:BP | GO:0034762 | regulation of transmembrane transport | 2 | PSEN2,PPP3CB | 392 | 0.6902875 |
| GO:BP | GO:0048584 | positive regulation of response to stimulus | 11 | VPS72,ADORA1,PPP3CB,SYNPO2L,ANKRD1,TRIM3,BDNF,KAT5,RBM14,RAD9A,PPP1CA | 1556 | 0.6904201 |
| GO:BP | GO:0061515 | myeloid cell development | 1 | PAFAH1B1 | 58 | 0.6904201 |
| GO:BP | GO:0018345 | protein palmitoylation | 1 | ZDHHC12 | 30 | 0.6923819 |
| GO:BP | GO:0046323 | glucose import | 1 | RPS6KB1 | 55 | 0.6926325 |
| GO:BP | GO:0006458 | ‘de novo’ protein folding | 1 | DNAJC18 | 39 | 0.6930381 |
| GO:BP | GO:0006305 | DNA alkylation | 1 | N6AMT1 | 41 | 0.6931038 |
| GO:BP | GO:0007416 | synapse assembly | 1 | BDNF | 152 | 0.6931038 |
| GO:BP | GO:0042168 | heme metabolic process | 1 | SRRD | 39 | 0.6931038 |
| GO:BP | GO:1902275 | regulation of chromatin organization | 1 | PHF20 | 45 | 0.6931038 |
| GO:BP | GO:1900181 | negative regulation of protein localization to nucleus | 1 | RAB23 | 30 | 0.6931038 |
| GO:BP | GO:0045580 | regulation of T cell differentiation | 1 | KAT5 | 110 | 0.6931038 |
| GO:BP | GO:0006306 | DNA methylation | 1 | N6AMT1 | 41 | 0.6931038 |
| GO:BP | GO:0006308 | DNA catabolic process | 1 | REXO4 | 25 | 0.6939877 |
| GO:BP | GO:0072006 | nephron development | 1 | AQP11 | 118 | 0.6943920 |
| GO:BP | GO:0051260 | protein homooligomerization | 3 | AQP11,TRMT61B,BCL11A | 138 | 0.6946174 |
| GO:BP | GO:0050679 | positive regulation of epithelial cell proliferation | 1 | SAAL1 | 152 | 0.6946174 |
| GO:BP | GO:0018193 | peptidyl-amino acid modification | 5 | VPS72,ADORA1,SUV39H2,BDNF,KAT5 | 866 | 0.6946174 |
| GO:BP | GO:0032412 | regulation of monoatomic ion transmembrane transporter activity | 1 | PPP3CB | 189 | 0.6946174 |
| GO:BP | GO:0002377 | immunoglobulin production | 1 | LIG4 | 70 | 0.6947946 |
| GO:BP | GO:0010827 | regulation of glucose transmembrane transport | 1 | RPS6KB1 | 56 | 0.6949302 |
| GO:BP | GO:0045923 | positive regulation of fatty acid metabolic process | 1 | PPARD | 27 | 0.6949302 |
| GO:BP | GO:0045860 | positive regulation of protein kinase activity | 1 | ADORA1 | 258 | 0.6949302 |
| GO:BP | GO:0050727 | regulation of inflammatory response | 2 | ADORA1,GSTP1 | 215 | 0.6949302 |
| GO:BP | GO:0071706 | tumor necrosis factor superfamily cytokine production | 1 | GSTP1 | 93 | 0.6949302 |
| GO:BP | GO:2000785 | regulation of autophagosome assembly | 1 | TMEM39A | 43 | 0.6949302 |
| GO:BP | GO:0006356 | regulation of transcription by RNA polymerase I | 1 | SMARCB1 | 47 | 0.6949302 |
| GO:BP | GO:1903214 | regulation of protein targeting to mitochondrion | 1 | PARL | 40 | 0.6949302 |
| GO:BP | GO:1903555 | regulation of tumor necrosis factor superfamily cytokine production | 1 | GSTP1 | 93 | 0.6949302 |
| GO:BP | GO:0006221 | pyrimidine nucleotide biosynthetic process | 1 | UPRT | 28 | 0.6950792 |
| GO:BP | GO:0009888 | tissue development | 4 | CPLANE2,HDAC1,LMO4,LMNA | 1423 | 0.6950792 |
| GO:BP | GO:0009218 | pyrimidine ribonucleotide metabolic process | 1 | UPRT | 26 | 0.6950792 |
| GO:BP | GO:1903708 | positive regulation of hemopoiesis | 1 | KAT5 | 118 | 0.6959312 |
| GO:BP | GO:1902107 | positive regulation of leukocyte differentiation | 1 | KAT5 | 118 | 0.6959312 |
| GO:BP | GO:0048536 | spleen development | 1 | TRAF3IP2 | 29 | 0.6962326 |
| GO:BP | GO:0050878 | regulation of body fluid levels | 1 | ADORA1 | 237 | 0.6964534 |
| GO:BP | GO:1902369 | negative regulation of RNA catabolic process | 2 | TENT2,TRAF3IP2 | 71 | 0.6964534 |
| GO:BP | GO:0008344 | adult locomotory behavior | 1 | PAFAH1B1 | 60 | 0.6982021 |
| GO:BP | GO:1904861 | excitatory synapse assembly | 1 | ZDHHC12 | 26 | 0.6982021 |
| GO:BP | GO:0045444 | fat cell differentiation | 5 | TTC8,METTL8,CTBP1,BBS7,PPARD | 186 | 0.7004425 |
| GO:BP | GO:0010033 | response to organic substance | 1 | AGTRAP | 1941 | 0.7007485 |
| GO:BP | GO:0051258 | protein polymerization | 2 | BLOC1S2,NAV3 | 237 | 0.7015393 |
| GO:BP | GO:0046513 | ceramide biosynthetic process | 1 | CERS4 | 53 | 0.7020855 |
| GO:BP | GO:0035329 | hippo signaling | 1 | MOB1B | 40 | 0.7020855 |
| GO:BP | GO:0043403 | skeletal muscle tissue regeneration | 1 | PPARD | 30 | 0.7021800 |
| GO:BP | GO:0010712 | regulation of collagen metabolic process | 1 | PPARD | 31 | 0.7021800 |
| GO:BP | GO:0040007 | growth | 16 | PPP3CB,BDNF,EI24,CDK4,ING1,TTC8,PML,PAFAH1B1,RPS6KB1,RPTOR,IMPACT,SERTAD1,BCL11A,OGFR,N6AMT1,SMARCB1 | 737 | 0.7033590 |
| GO:BP | GO:0006270 | DNA replication initiation | 1 | ORC5 | 35 | 0.7035746 |
| GO:BP | GO:1901888 | regulation of cell junction assembly | 1 | BDNF | 165 | 0.7042063 |
| GO:BP | GO:0072698 | protein localization to microtubule cytoskeleton | 1 | NSFL1C | 51 | 0.7046992 |
| GO:BP | GO:0022898 | regulation of transmembrane transporter activity | 1 | PPP3CB | 200 | 0.7069685 |
| GO:BP | GO:0006275 | regulation of DNA replication | 3 | INO80D,ACTL6A,ORC5 | 116 | 0.7069685 |
| GO:BP | GO:0007173 | epidermal growth factor receptor signaling pathway | 2 | CHMP6,RAB7A | 89 | 0.7069685 |
| GO:BP | GO:0016525 | negative regulation of angiogenesis | 1 | PML | 71 | 0.7071448 |
| GO:BP | GO:1900225 | regulation of NLRP3 inflammasome complex assembly | 1 | ZDHHC12 | 26 | 0.7073112 |
| GO:BP | GO:0010629 | negative regulation of gene expression | 8 | HDAC1,LMNA,SUV39H2,TRIM3,CLP1,POLR2G,KAT5,GSTP1 | 823 | 0.7086255 |
| GO:BP | GO:0035633 | maintenance of blood-brain barrier | 1 | CLDN12 | 29 | 0.7093136 |
| GO:BP | GO:0051050 | positive regulation of transport | 3 | ADORA1,PPP3CB,ANKRD1 | 665 | 0.7098805 |
| GO:BP | GO:2000181 | negative regulation of blood vessel morphogenesis | 1 | PML | 72 | 0.7103904 |
| GO:BP | GO:0061053 | somite development | 1 | NLE1 | 62 | 0.7121463 |
| GO:BP | GO:0006953 | acute-phase response | 1 | APOL2 | 19 | 0.7127631 |
| GO:BP | GO:0044283 | small molecule biosynthetic process | 6 | IPMK,GSTP1,CRY1,PRKAB1,HSD17B1,OSBPL7 | 433 | 0.7127631 |
| GO:BP | GO:0140747 | regulation of ncRNA transcription | 2 | SMARCB1,PPARD | 79 | 0.7135883 |
| GO:BP | GO:1901343 | negative regulation of vasculature development | 1 | PML | 72 | 0.7135883 |
| GO:BP | GO:0034620 | cellular response to unfolded protein | 2 | BAK1,UFL1 | 83 | 0.7137517 |
| GO:BP | GO:0006139 | nucleobase-containing compound metabolic process | 2 | ICMT,PEX14 | 4487 | 0.7139602 |
| GO:BP | GO:0046777 | protein autophosphorylation | 1 | STK33 | 183 | 0.7175633 |
| GO:BP | GO:0065008 | regulation of biological quality | 1 | AGTRAP | 2083 | 0.7194153 |
| GO:BP | GO:0000910 | cytokinesis | 3 | CHMP1A,CHMP6,SEPTIN2 | 164 | 0.7194153 |
| GO:BP | GO:0030098 | lymphocyte differentiation | 2 | PPP3CB,KAT5 | 262 | 0.7195500 |
| GO:BP | GO:0009991 | response to extracellular stimulus | 6 | KAT5,PRKAB1,WDR24,RPS6KB1,RPTOR,IMPACT | 379 | 0.7197770 |
| GO:BP | GO:0006401 | RNA catabolic process | 4 | POLR2G,CASC3,EIF4A3,SMG9 | 261 | 0.7199686 |
| GO:BP | GO:0019932 | second-messenger-mediated signaling | 1 | PPP3CB | 182 | 0.7210202 |
| GO:BP | GO:0042092 | type 2 immune response | 1 | TRAF3IP2 | 19 | 0.7210202 |
| GO:BP | GO:0050900 | leukocyte migration | 1 | ADORA1 | 207 | 0.7210202 |
| GO:BP | GO:0010468 | regulation of gene expression | 82 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,ZNF195,TRIM3,ZNF408,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,GSTP1,EMSY,MED17,ANKRD49,MLF2,CDK4,TBK1,NAV3,CRY1,PRKAB1,TRIAP1,KMT5A,RAN,ZNF605,GTF2F2,ING1,BRF1,BAHD1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,CHMP1A,ZNF287,CASC3,HEXIM1,SRSF1,RPS6KB1,INTS2,EIF4A3,RPTOR,RIOK3,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,SMG9,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,RAB1A,ZNF638 | 3590 | 0.7210611 |
| GO:BP | GO:2000573 | positive regulation of DNA biosynthetic process | 1 | MAP2K7 | 66 | 0.7235654 |
| GO:BP | GO:0017004 | cytochrome complex assembly | 1 | COX19 | 38 | 0.7243831 |
| GO:BP | GO:0030324 | lung development | 1 | PPP1CA | 144 | 0.7253746 |
| GO:BP | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | 1 | PHF20L1 | 35 | 0.7261386 |
| GO:BP | GO:0051093 | negative regulation of developmental process | 1 | HDAC1 | 652 | 0.7261386 |
| GO:BP | GO:0044546 | NLRP3 inflammasome complex assembly | 1 | ZDHHC12 | 26 | 0.7261386 |
| GO:BP | GO:0032409 | regulation of transporter activity | 1 | PPP3CB | 212 | 0.7265792 |
| GO:BP | GO:0032480 | negative regulation of type I interferon production | 1 | RNF216 | 30 | 0.7267441 |
| GO:BP | GO:0060041 | retina development in camera-type eye | 3 | TTC8,RDH13,ACTL6A | 109 | 0.7267441 |
| GO:BP | GO:0007009 | plasma membrane organization | 2 | CHMP1A,CHMP6 | 114 | 0.7267441 |
| GO:BP | GO:0019362 | pyridine nucleotide metabolic process | 1 | RPTOR | 64 | 0.7280169 |
| GO:BP | GO:0046496 | nicotinamide nucleotide metabolic process | 1 | RPTOR | 64 | 0.7280169 |
| GO:BP | GO:0044380 | protein localization to cytoskeleton | 1 | NSFL1C | 54 | 0.7280480 |
| GO:BP | GO:0042119 | neutrophil activation | 1 | TRAF3IP2 | 16 | 0.7281148 |
| GO:BP | GO:0098586 | cellular response to virus | 1 | RIOK3 | 40 | 0.7290848 |
| GO:BP | GO:0046483 | heterocycle metabolic process | 2 | ICMT,PEX14 | 4601 | 0.7290848 |
| GO:BP | GO:0051607 | defense response to virus | 8 | TBK1,PML,RIOK3,DHX16,TRAF3IP2,RNF216,TRIM35,ZDHHC12 | 223 | 0.7290848 |
| GO:BP | GO:0072089 | stem cell proliferation | 1 | LIG4 | 84 | 0.7295655 |
| GO:BP | GO:0050792 | regulation of viral process | 3 | HEXIM1,TMEM39A,RAB7A | 124 | 0.7300939 |
| GO:BP | GO:0006665 | sphingolipid metabolic process | 2 | GLTP,CERS4 | 129 | 0.7300939 |
| GO:BP | GO:0030323 | respiratory tube development | 1 | PPP1CA | 148 | 0.7305273 |
| GO:BP | GO:0008277 | regulation of G protein-coupled receptor signaling pathway | 1 | CRY1 | 93 | 0.7305273 |
| GO:BP | GO:0070296 | sarcoplasmic reticulum calcium ion transport | 1 | SRI | 32 | 0.7306392 |
| GO:BP | GO:0001934 | positive regulation of protein phosphorylation | 8 | ADORA1,BDNF,TBK1,WDR24,ARL2BP,RPTOR,MOB3A,MAP2K7 | 465 | 0.7306392 |
| GO:BP | GO:0032964 | collagen biosynthetic process | 1 | PPARD | 36 | 0.7306392 |
| GO:BP | GO:0055010 | ventricular cardiac muscle tissue morphogenesis | 1 | PTCD2 | 44 | 0.7306392 |
| GO:BP | GO:0032943 | mononuclear cell proliferation | 2 | PPP3CB,TBK1 | 168 | 0.7306392 |
| GO:BP | GO:0033555 | multicellular organismal response to stress | 2 | RPS6KB1,PRKAR1B | 58 | 0.7306392 |
| GO:BP | GO:0051224 | negative regulation of protein transport | 3 | UBAC2,RAB23,SNX12 | 94 | 0.7306392 |
| GO:BP | GO:0140546 | defense response to symbiont | 8 | TBK1,PML,RIOK3,DHX16,TRAF3IP2,RNF216,TRIM35,ZDHHC12 | 223 | 0.7306392 |
| GO:BP | GO:0001974 | blood vessel remodeling | 1 | BAK1 | 32 | 0.7306392 |
| GO:BP | GO:0060996 | dendritic spine development | 1 | PAFAH1B1 | 82 | 0.7308448 |
| GO:BP | GO:0141085 | regulation of inflammasome-mediated signaling pathway | 1 | ZDHHC12 | 28 | 0.7310912 |
| GO:BP | GO:0043113 | receptor clustering | 1 | PICK1 | 40 | 0.7310912 |
| GO:BP | GO:0035196 | miRNA processing | 1 | SRSF3 | 41 | 0.7310912 |
| GO:BP | GO:0006725 | cellular aromatic compound metabolic process | 2 | ICMT,PEX14 | 4625 | 0.7312774 |
| GO:BP | GO:0032757 | positive regulation of interleukin-8 production | 1 | RAB1A | 30 | 0.7315598 |
| GO:BP | GO:0007165 | signal transduction | 3 | AGTRAP,CPLANE2,ARHGEF10L | 3803 | 0.7315598 |
| GO:BP | GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 1 | PPP3CB | 172 | 0.7315598 |
| GO:BP | GO:1903747 | regulation of establishment of protein localization to mitochondrion | 1 | PARL | 45 | 0.7315598 |
| GO:BP | GO:0043413 | macromolecule glycosylation | 2 | AQP11,COG7 | 186 | 0.7323553 |
| GO:BP | GO:0006486 | protein glycosylation | 2 | AQP11,COG7 | 186 | 0.7323553 |
| GO:BP | GO:1902476 | chloride transmembrane transport | 1 | SLC12A4 | 50 | 0.7344390 |
| GO:BP | GO:0007167 | enzyme-linked receptor protein signaling pathway | 1 | HDAC1 | 741 | 0.7354506 |
| GO:BP | GO:0046651 | lymphocyte proliferation | 1 | PPP3CB | 162 | 0.7357743 |
| GO:BP | GO:0048260 | positive regulation of receptor-mediated endocytosis | 1 | PICK1 | 42 | 0.7366026 |
| GO:BP | GO:0071248 | cellular response to metal ion | 2 | LIG4,HSD17B1 | 142 | 0.7377558 |
| GO:BP | GO:0048525 | negative regulation of viral process | 1 | HEXIM1 | 65 | 0.7388113 |
| GO:BP | GO:0045619 | regulation of lymphocyte differentiation | 1 | KAT5 | 131 | 0.7388113 |
| GO:BP | GO:0140632 | canonical inflammasome complex assembly | 1 | ZDHHC12 | 26 | 0.7389148 |
| GO:BP | GO:0002682 | regulation of immune system process | 1 | PITHD1 | 908 | 0.7391537 |
| GO:BP | GO:0032386 | regulation of intracellular transport | 8 | RAN,UBAC2,EIPR1,PARL,RIOK2,RAB23,RINT1,SNX12 | 293 | 0.7393768 |
| GO:BP | GO:0050807 | regulation of synapse organization | 3 | BDNF,PAFAH1B1,LRFN3 | 184 | 0.7399552 |
| GO:BP | GO:0033627 | cell adhesion mediated by integrin | 1 | RAC3 | 61 | 0.7400813 |
| GO:BP | GO:1903828 | negative regulation of protein localization | 5 | UBAC2,PIAS4,NSFL1C,RAB23,SNX12 | 171 | 0.7406481 |
| GO:BP | GO:0006081 | cellular aldehyde metabolic process | 1 | RDH13 | 52 | 0.7413884 |
| GO:BP | GO:0019748 | secondary metabolic process | 1 | N6AMT1 | 33 | 0.7417340 |
| GO:BP | GO:0009150 | purine ribonucleotide metabolic process | 3 | RAN,PPCDC,EFL1 | 292 | 0.7417340 |
| GO:BP | GO:0048546 | digestive tract morphogenesis | 1 | BBS7 | 31 | 0.7425879 |
| GO:BP | GO:0034661 | ncRNA catabolic process | 1 | TENT2 | 45 | 0.7428103 |
| GO:BP | GO:0050865 | regulation of cell activation | 1 | LMO4 | 378 | 0.7437372 |
| GO:BP | GO:0016125 | sterol metabolic process | 3 | APOL2,FAXDC2,PPARD | 108 | 0.7437372 |
| GO:BP | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol | 1 | SRI | 27 | 0.7437552 |
| GO:BP | GO:0010586 | miRNA metabolic process | 2 | TENT2,PPARD | 85 | 0.7437881 |
| GO:BP | GO:0050771 | negative regulation of axonogenesis | 1 | BCL11A | 59 | 0.7437881 |
| GO:BP | GO:0072528 | pyrimidine-containing compound biosynthetic process | 1 | UPRT | 34 | 0.7438635 |
| GO:BP | GO:0032101 | regulation of response to external stimulus | 5 | ADORA1,TRIM3,KAT5,RBM14,GSTP1 | 689 | 0.7444997 |
| GO:BP | GO:0032102 | negative regulation of response to external stimulus | 1 | ADORA1 | 291 | 0.7444997 |
| GO:BP | GO:0097106 | postsynaptic density organization | 1 | ZDHHC12 | 30 | 0.7452070 |
| GO:BP | GO:0048878 | chemical homeostasis | 5 | ADORA1,PPP3CB,KAT5,GSTP1,AQP11 | 690 | 0.7452070 |
| GO:BP | GO:1904950 | negative regulation of establishment of protein localization | 1 | UBAC2 | 98 | 0.7452070 |
| GO:BP | GO:0099068 | postsynapse assembly | 1 | ZDHHC12 | 31 | 0.7452070 |
| GO:BP | GO:0022414 | reproductive process | 1 | PITHD1 | 924 | 0.7452070 |
| GO:BP | GO:0072524 | pyridine-containing compound metabolic process | 1 | RPTOR | 70 | 0.7457872 |
| GO:BP | GO:0001501 | skeletal system development | 6 | PAFAH1B1,NLE1,HSD17B1,MKS1,EIF4A3,SLC39A3 | 361 | 0.7457872 |
| GO:BP | GO:0042391 | regulation of membrane potential | 1 | ADORA1 | 295 | 0.7457872 |
| GO:BP | GO:0000003 | reproduction | 1 | PITHD1 | 933 | 0.7472959 |
| GO:BP | GO:0008306 | associative learning | 1 | EIF4A3 | 65 | 0.7476280 |
| GO:BP | GO:0015711 | organic anion transport | 1 | ADORA1 | 270 | 0.7479603 |
| GO:BP | GO:0045840 | positive regulation of mitotic nuclear division | 1 | MAD1L1 | 29 | 0.7496623 |
| GO:BP | GO:1901360 | organic cyclic compound metabolic process | 2 | ICMT,PEX14 | 4777 | 0.7496623 |
| GO:BP | GO:0099175 | regulation of postsynapse organization | 1 | PAFAH1B1 | 83 | 0.7496623 |
| GO:BP | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1 | FBXL4 | 44 | 0.7496623 |
| GO:BP | GO:0051321 | meiotic cell cycle | 1 | BUB3 | 183 | 0.7503509 |
| GO:BP | GO:0010608 | post-transcriptional regulation of gene expression | 5 | JMJD4,TRIM3,CLP1,POLR2G,PPP1CA | 478 | 0.7503509 |
| GO:BP | GO:0010466 | negative regulation of peptidase activity | 2 | TRIAP1,NLE1 | 123 | 0.7503509 |
| GO:BP | GO:0046148 | pigment biosynthetic process | 1 | SRRD | 47 | 0.7514243 |
| GO:BP | GO:0001658 | branching involved in ureteric bud morphogenesis | 1 | GZF1 | 43 | 0.7514842 |
| GO:BP | GO:0030316 | osteoclast differentiation | 1 | PAFAH1B1 | 65 | 0.7524217 |
| GO:BP | GO:0048806 | genitalia development | 1 | BAK1 | 28 | 0.7528610 |
| GO:BP | GO:0031641 | regulation of myelination | 1 | NSUN5 | 35 | 0.7528610 |
| GO:BP | GO:0050803 | regulation of synapse structure or activity | 1 | BDNF | 188 | 0.7528610 |
| GO:BP | GO:0031018 | endocrine pancreas development | 1 | BAK1 | 30 | 0.7528610 |
| GO:BP | GO:0009605 | response to external stimulus | 1 | PLEKHM2 | 1637 | 0.7532387 |
| GO:BP | GO:0010647 | positive regulation of cell communication | 8 | ADORA1,PPP3CB,SYNPO2L,ANKRD1,TRIM3,BDNF,RAD9A,PPP1CA | 1248 | 0.7532387 |
| GO:BP | GO:0016064 | immunoglobulin mediated immune response | 1 | LIG4 | 76 | 0.7538210 |
| GO:BP | GO:0035282 | segmentation | 1 | NLE1 | 70 | 0.7562002 |
| GO:BP | GO:0071902 | positive regulation of protein serine/threonine kinase activity | 3 | RPTOR,MAP2K7,SPATC1L | 132 | 0.7572392 |
| GO:BP | GO:0072538 | T-helper 17 type immune response | 1 | TRAF3IP2 | 27 | 0.7577287 |
| GO:BP | GO:0006119 | oxidative phosphorylation | 2 | TEFM,DGUOK | 125 | 0.7583521 |
| GO:BP | GO:0060541 | respiratory system development | 1 | PPP1CA | 161 | 0.7583521 |
| GO:BP | GO:0006457 | protein folding | 4 | TBCEL,RANBP2,DNAJC5,DNAJC18 | 189 | 0.7585226 |
| GO:BP | GO:0141084 | inflammasome-mediated signaling pathway | 1 | ZDHHC12 | 28 | 0.7588630 |
| GO:BP | GO:0007215 | glutamate receptor signaling pathway | 1 | CPEB4 | 29 | 0.7592595 |
| GO:BP | GO:0034032 | purine nucleoside bisphosphate metabolic process | 1 | PPCDC | 92 | 0.7605108 |
| GO:BP | GO:0033875 | ribonucleoside bisphosphate metabolic process | 1 | PPCDC | 92 | 0.7605108 |
| GO:BP | GO:0033865 | nucleoside bisphosphate metabolic process | 1 | PPCDC | 92 | 0.7605108 |
| GO:BP | GO:0019724 | B cell mediated immunity | 1 | LIG4 | 77 | 0.7607772 |
| GO:BP | GO:0002253 | activation of immune response | 3 | TRIM3,RBM14,TBK1 | 296 | 0.7608498 |
| GO:BP | GO:0050778 | positive regulation of immune response | 3 | TRIM3,KAT5,RBM14 | 400 | 0.7608498 |
| GO:BP | GO:0072001 | renal system development | 3 | AQP11,TTC8,NLE1 | 252 | 0.7608498 |
| GO:BP | GO:0006096 | glycolytic process | 1 | RPTOR | 74 | 0.7619572 |
| GO:BP | GO:0006066 | alcohol metabolic process | 1 | IPMK | 263 | 0.7627094 |
| GO:BP | GO:0034641 | cellular nitrogen compound metabolic process | 2 | ICMT,PEX14 | 4979 | 0.7627094 |
| GO:BP | GO:1903131 | mononuclear cell differentiation | 2 | PPP3CB,KAT5 | 295 | 0.7627094 |
| GO:BP | GO:1903311 | regulation of mRNA metabolic process | 6 | POLR2G,CASC3,EIF4A3,PTCD2,SRSF3,TRAF3IP2 | 255 | 0.7627094 |
| GO:BP | GO:0007595 | lactation | 1 | UPRT | 32 | 0.7640588 |
| GO:BP | GO:0014003 | oligodendrocyte development | 1 | NSUN5 | 30 | 0.7654362 |
| GO:BP | GO:0048662 | negative regulation of smooth muscle cell proliferation | 1 | PPARD | 39 | 0.7657360 |
| GO:BP | GO:0120161 | regulation of cold-induced thermogenesis | 1 | PRKAB1 | 114 | 0.7666613 |
| GO:BP | GO:0031330 | negative regulation of cellular catabolic process | 4 | RPTOR,TMEM39A,TENT2,TRAF3IP2 | 170 | 0.7668970 |
| GO:BP | GO:0050433 | regulation of catecholamine secretion | 1 | ADRA2C | 29 | 0.7675721 |
| GO:BP | GO:0044000 | movement in host | 2 | CHMP1A,CHMP6 | 140 | 0.7681063 |
| GO:BP | GO:0106106 | cold-induced thermogenesis | 1 | PRKAB1 | 115 | 0.7685662 |
| GO:BP | GO:0007265 | Ras protein signal transduction | 1 | SYNPO2L | 287 | 0.7689191 |
| GO:BP | GO:0002269 | leukocyte activation involved in inflammatory response | 1 | TRAF3IP2 | 21 | 0.7690494 |
| GO:BP | GO:0036230 | granulocyte activation | 1 | TRAF3IP2 | 19 | 0.7690494 |
| GO:BP | GO:0022612 | gland morphogenesis | 1 | PML | 99 | 0.7692925 |
| GO:BP | GO:0009259 | ribonucleotide metabolic process | 3 | RAN,PPCDC,EFL1 | 309 | 0.7692925 |
| GO:BP | GO:0038127 | ERBB signaling pathway | 2 | CHMP6,RAB7A | 103 | 0.7693117 |
| GO:BP | GO:0060348 | bone development | 2 | PAFAH1B1,HSD17B1 | 157 | 0.7698255 |
| GO:BP | GO:0046394 | carboxylic acid biosynthetic process | 3 | GSTP1,PRKAB1,OSBPL7 | 224 | 0.7698407 |
| GO:BP | GO:0006812 | monoatomic cation transport | 3 | ADORA1,PSEN2,PPP3CB | 678 | 0.7704829 |
| GO:BP | GO:2000243 | positive regulation of reproductive process | 1 | SYDE1 | 51 | 0.7711635 |
| GO:BP | GO:0006940 | regulation of smooth muscle contraction | 1 | ADRA2C | 39 | 0.7719525 |
| GO:BP | GO:0006576 | biogenic amine metabolic process | 1 | GDPD1 | 57 | 0.7719525 |
| GO:BP | GO:0032869 | cellular response to insulin stimulus | 2 | CDK4,RPS6KB1 | 168 | 0.7729455 |
| GO:BP | GO:1901566 | organonitrogen compound biosynthetic process | 22 | MRPL9,PIGC,JMJD4,TRIM3,POLR2G,PPP1CA,GSTP1,AQP11,PHLDA1,BRF1,TRIP4,PML,PPCDC,EFL1,COG7,CASC3,RSAD1,RPS6KB1,EIF4A3,IMPACT,CERS4,FARSA | 1497 | 0.7745474 |
| GO:BP | GO:0002088 | lens development in camera-type eye | 1 | FZR1 | 57 | 0.7749383 |
| GO:BP | GO:0006821 | chloride transport | 1 | SLC12A4 | 57 | 0.7749383 |
| GO:BP | GO:0016053 | organic acid biosynthetic process | 3 | GSTP1,PRKAB1,OSBPL7 | 225 | 0.7749383 |
| GO:BP | GO:0043410 | positive regulation of MAPK cascade | 1 | ADORA1 | 316 | 0.7760684 |
| GO:BP | GO:0098657 | import into cell | 4 | ADORA1,PPP3CB,AP2A2,ANKRD13D | 662 | 0.7776193 |
| GO:BP | GO:0048469 | cell maturation | 3 | RAC3,BCL11A,PICK1 | 110 | 0.7788167 |
| GO:BP | GO:0003229 | ventricular cardiac muscle tissue development | 1 | PTCD2 | 53 | 0.7788567 |
| GO:BP | GO:0050870 | positive regulation of T cell activation | 1 | KAT5 | 144 | 0.7789609 |
| GO:BP | GO:0050789 | regulation of biological process | 8 | WRAP73,PEX14,AGTRAP,PLEKHM2,CPLANE2,ARHGEF10L,ASAP3,PITHD1 | 8024 | 0.7793075 |
| GO:BP | GO:0002697 | regulation of immune effector process | 2 | PPP3CB,C12orf4 | 195 | 0.7793075 |
| GO:BP | GO:0007275 | multicellular organism development | 3 | CPLANE2,PITHD1,LYPLA2 | 3348 | 0.7793075 |
| GO:BP | GO:0006968 | cellular defense response | 1 | RAB23 | 15 | 0.7800174 |
| GO:BP | GO:0140013 | meiotic nuclear division | 2 | ERCC4,FZR1 | 117 | 0.7800174 |
| GO:BP | GO:0001938 | positive regulation of endothelial cell proliferation | 1 | RPTOR | 74 | 0.7800174 |
| GO:BP | GO:0033108 | mitochondrial respiratory chain complex assembly | 2 | LYRM2,COX19 | 96 | 0.7800174 |
| GO:BP | GO:0035966 | response to topologically incorrect protein | 3 | DNAJC18,BAK1,UFL1 | 148 | 0.7800174 |
| GO:BP | GO:0019693 | ribose phosphate metabolic process | 3 | RAN,PPCDC,EFL1 | 317 | 0.7806816 |
| GO:BP | GO:0060675 | ureteric bud morphogenesis | 1 | GZF1 | 49 | 0.7812234 |
| GO:BP | GO:0072593 | reactive oxygen species metabolic process | 1 | GSTP1 | 157 | 0.7824233 |
| GO:BP | GO:0023052 | signaling | 3 | AGTRAP,CPLANE2,ARHGEF10L | 4134 | 0.7827427 |
| GO:BP | GO:1901654 | response to ketone | 2 | CDK4,RPS6KB1 | 144 | 0.7827427 |
| GO:BP | GO:0099084 | postsynaptic specialization organization | 1 | ZDHHC12 | 36 | 0.7840843 |
| GO:BP | GO:0072171 | mesonephric tubule morphogenesis | 1 | GZF1 | 50 | 0.7860252 |
| GO:BP | GO:0042093 | T-helper cell differentiation | 1 | STAT4 | 44 | 0.7867478 |
| GO:BP | GO:0008202 | steroid metabolic process | 6 | HSD17B1,OSBPL7,PIAS4,APOL2,FAXDC2,PPARD | 203 | 0.7867478 |
| GO:BP | GO:0050432 | catecholamine secretion | 1 | ADRA2C | 33 | 0.7867824 |
| GO:BP | GO:0099173 | postsynapse organization | 2 | PAFAH1B1,RAC3 | 159 | 0.7870988 |
| GO:BP | GO:0007127 | meiosis I | 1 | ERCC4 | 73 | 0.7871750 |
| GO:BP | GO:0007565 | female pregnancy | 4 | SYDE1,APOL2,PPARD,UPRT | 123 | 0.7872317 |
| GO:BP | GO:0007268 | chemical synaptic transmission | 2 | ADORA1,PPP3CB | 490 | 0.7872317 |
| GO:BP | GO:0098916 | anterograde trans-synaptic signaling | 2 | ADORA1,PPP3CB | 490 | 0.7872317 |
| GO:BP | GO:0061951 | establishment of protein localization to plasma membrane | 1 | RAB7A | 59 | 0.7872317 |
| GO:BP | GO:0001523 | retinoid metabolic process | 1 | RDH13 | 39 | 0.7872317 |
| GO:BP | GO:0002366 | leukocyte activation involved in immune response | 2 | C12orf4,LIG4 | 158 | 0.7872317 |
| GO:BP | GO:0048592 | eye morphogenesis | 2 | TTC8,RDH13 | 114 | 0.7872373 |
| GO:BP | GO:0009408 | response to heat | 1 | MAP2K7 | 74 | 0.7876847 |
| GO:BP | GO:0051262 | protein tetramerization | 1 | FARSA | 64 | 0.7876847 |
| GO:BP | GO:0048589 | developmental growth | 7 | PPP3CB,BDNF,CDK4,TTC8,PAFAH1B1,RPS6KB1,IMPACT | 523 | 0.7876847 |
| GO:BP | GO:0005975 | carbohydrate metabolic process | 1 | DUSP12 | 439 | 0.7892067 |
| GO:BP | GO:0098661 | inorganic anion transmembrane transport | 1 | SLC12A4 | 64 | 0.7897331 |
| GO:BP | GO:0099537 | trans-synaptic signaling | 2 | ADORA1,PPP3CB | 494 | 0.7897331 |
| GO:BP | GO:0030879 | mammary gland development | 1 | PML | 105 | 0.7897331 |
| GO:BP | GO:0090316 | positive regulation of intracellular protein transport | 1 | RAN | 135 | 0.7915252 |
| GO:BP | GO:0009617 | response to bacterium | 4 | ANKRD1,GSTP1,CDK4,TBK1 | 326 | 0.7917604 |
| GO:BP | GO:0002263 | cell activation involved in immune response | 2 | C12orf4,LIG4 | 161 | 0.7919914 |
| GO:BP | GO:0007154 | cell communication | 3 | AGTRAP,CPLANE2,ARHGEF10L | 4210 | 0.7919914 |
| GO:BP | GO:0002294 | CD4-positive, alpha-beta T cell differentiation involved in immune response | 1 | STAT4 | 44 | 0.7927426 |
| GO:BP | GO:0009100 | glycoprotein metabolic process | 3 | AQP11,PHLDA1,COG7 | 316 | 0.7927426 |
| GO:BP | GO:0046330 | positive regulation of JNK cascade | 1 | MAP2K7 | 71 | 0.7937380 |
| GO:BP | GO:0050906 | detection of stimulus involved in sensory perception | 1 | ADORA1 | 38 | 0.7942320 |
| GO:BP | GO:0018198 | peptidyl-cysteine modification | 1 | ZDHHC12 | 41 | 0.7947954 |
| GO:BP | GO:2000677 | regulation of transcription regulatory region DNA binding | 1 | SRI | 43 | 0.7947954 |
| GO:BP | GO:0048519 | negative regulation of biological process | 30 | PEX14,HDAC1,LMO4,VPS72,LMNA,TIPRL,ADORA1,AIDA,SDE2,PSEN2,SUV39H2,HERC4,PPP3CB,ANKRD1,BUB3,TRIM3,STK33,BDNF,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,ANKRD13D,RAD9A,GSTP1,ARAP1,THAP12,AQP11 | 4025 | 0.7950759 |
| GO:BP | GO:0030003 | intracellular monoatomic cation homeostasis | 1 | ADORA1 | 364 | 0.7955659 |
| GO:BP | GO:0038061 | non-canonical NF-kappaB signal transduction | 2 | TERF2IP,MKRN2 | 94 | 0.7955659 |
| GO:BP | GO:0002287 | alpha-beta T cell activation involved in immune response | 1 | STAT4 | 44 | 0.7959021 |
| GO:BP | GO:0002293 | alpha-beta T cell differentiation involved in immune response | 1 | STAT4 | 44 | 0.7959021 |
| GO:BP | GO:0016101 | diterpenoid metabolic process | 1 | RDH13 | 42 | 0.7959681 |
| GO:BP | GO:0010556 | regulation of macromolecule biosynthetic process | 82 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,ZNF195,TRIM3,ZNF408,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,GSTP1,EMSY,MED17,ANKRD49,MLF2,CDK4,TBK1,NAV3,CRY1,PRKAB1,TRIAP1,KMT5A,RAN,ZNF605,GTF2F2,ING1,BRF1,BAHD1,TRIP4,PML,ARL2BP,E2F4,ZFP90,TERF2IP,CHMP1A,ZNF287,CASC3,HEXIM1,SRSF1,RPS6KB1,INTS2,EIF4A3,RPTOR,RIOK3,IMPACT,MIER2,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,SMG9,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,RAB1A,ZNF638 | 3705 | 0.7959681 |
| GO:BP | GO:1990845 | adaptive thermogenesis | 1 | PRKAB1 | 126 | 0.7959681 |
| GO:BP | GO:0061982 | meiosis I cell cycle process | 1 | ERCC4 | 77 | 0.7982088 |
| GO:BP | GO:0019229 | regulation of vasoconstriction | 1 | ADRA2C | 38 | 0.7984454 |
| GO:BP | GO:0098771 | inorganic ion homeostasis | 1 | ADORA1 | 355 | 0.7991823 |
| GO:BP | GO:2000649 | regulation of sodium ion transmembrane transporter activity | 1 | TMEM168 | 42 | 0.7994251 |
| GO:BP | GO:0006873 | intracellular monoatomic ion homeostasis | 1 | ADORA1 | 369 | 0.8002824 |
| GO:BP | GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 1 | KAT5 | 157 | 0.8027984 |
| GO:BP | GO:0010035 | response to inorganic substance | 1 | ADORA1 | 393 | 0.8029131 |
| GO:BP | GO:0099536 | synaptic signaling | 2 | ADORA1,PPP3CB | 512 | 0.8031071 |
| GO:BP | GO:0015695 | organic cation transport | 1 | ADRA2C | 35 | 0.8031646 |
| GO:BP | GO:0002931 | response to ischemia | 1 | CPEB4 | 48 | 0.8040220 |
| GO:BP | GO:0016126 | sterol biosynthetic process | 1 | FAXDC2 | 53 | 0.8064533 |
| GO:BP | GO:0051701 | biological process involved in interaction with host | 2 | CHMP1A,CHMP6 | 153 | 0.8075436 |
| GO:BP | GO:0048562 | embryonic organ morphogenesis | 5 | CLUAP1,EIF4A3,SLC39A3,IFT52,BBS7 | 186 | 0.8075436 |
| GO:BP | GO:0014009 | glial cell proliferation | 1 | UFL1 | 40 | 0.8077016 |
| GO:BP | GO:0048771 | tissue remodeling | 3 | PML,RAB7A,BAK1 | 115 | 0.8089128 |
| GO:BP | GO:0002534 | cytokine production involved in inflammatory response | 1 | MACIR | 35 | 0.8096992 |
| GO:BP | GO:1900015 | regulation of cytokine production involved in inflammatory response | 1 | MACIR | 35 | 0.8096992 |
| GO:BP | GO:0003206 | cardiac chamber morphogenesis | 2 | MKS1,PTCD2 | 110 | 0.8096992 |
| GO:BP | GO:0015908 | fatty acid transport | 2 | RPS6KB1,PPARD | 58 | 0.8097325 |
| GO:BP | GO:0032677 | regulation of interleukin-8 production | 1 | RAB1A | 42 | 0.8097325 |
| GO:BP | GO:0032637 | interleukin-8 production | 1 | RAB1A | 42 | 0.8097325 |
| GO:BP | GO:0021987 | cerebral cortex development | 1 | PAFAH1B1 | 102 | 0.8110393 |
| GO:BP | GO:0045453 | bone resorption | 1 | RAB7A | 41 | 0.8122675 |
| GO:BP | GO:0050793 | regulation of developmental process | 2 | PITHD1,HDAC1 | 1810 | 0.8135069 |
| GO:BP | GO:0007166 | cell surface receptor signaling pathway | 1 | CPLANE2 | 1889 | 0.8152205 |
| GO:BP | GO:0071345 | cellular response to cytokine stimulus | 9 | ANKRD1,GSTP1,CDK4,TBK1,PML,PAFAH1B1,RPS6KB1,PIAS4,MAP2K7 | 544 | 0.8153765 |
| GO:BP | GO:0042110 | T cell activation | 2 | PPP3CB,KAT5 | 317 | 0.8156815 |
| GO:BP | GO:0097194 | execution phase of apoptosis | 1 | BLCAP | 52 | 0.8163223 |
| GO:BP | GO:1901137 | carbohydrate derivative biosynthetic process | 5 | PIGC,AQP11,PHLDA1,PPCDC,COG7 | 546 | 0.8183235 |
| GO:BP | GO:0072078 | nephron tubule morphogenesis | 1 | GZF1 | 58 | 0.8192845 |
| GO:BP | GO:0034097 | response to cytokine | 5 | PPP3CB,ANKRD1,GSTP1,CDK4,TBK1 | 608 | 0.8201060 |
| GO:BP | GO:1903046 | meiotic cell cycle process | 2 | ERCC4,FZR1 | 132 | 0.8201060 |
| GO:BP | GO:0070231 | T cell apoptotic process | 1 | BAK1 | 41 | 0.8201060 |
| GO:BP | GO:0010038 | response to metal ion | 3 | PPP1CA,LIG4,HSD17B1 | 261 | 0.8201060 |
| GO:BP | GO:0048871 | multicellular organismal-level homeostasis | 2 | ADORA1,PPP3CB | 569 | 0.8243077 |
| GO:BP | GO:0043954 | cellular component maintenance | 1 | PICK1 | 60 | 0.8243077 |
| GO:BP | GO:0009308 | amine metabolic process | 1 | GDPD1 | 68 | 0.8244642 |
| GO:BP | GO:0002292 | T cell differentiation involved in immune response | 1 | STAT4 | 46 | 0.8260997 |
| GO:BP | GO:0070663 | regulation of leukocyte proliferation | 1 | GSTP1 | 140 | 0.8264725 |
| GO:BP | GO:0072088 | nephron epithelium morphogenesis | 1 | GZF1 | 60 | 0.8266877 |
| GO:BP | GO:0006672 | ceramide metabolic process | 1 | CERS4 | 81 | 0.8274458 |
| GO:BP | GO:1904035 | regulation of epithelial cell apoptotic process | 1 | PIAS4 | 74 | 0.8279605 |
| GO:BP | GO:0098656 | monoatomic anion transmembrane transport | 1 | SLC12A4 | 80 | 0.8292324 |
| GO:BP | GO:0032271 | regulation of protein polymerization | 1 | NAV3 | 164 | 0.8292543 |
| GO:BP | GO:0031638 | zymogen activation | 1 | BAK1 | 46 | 0.8294911 |
| GO:BP | GO:0006766 | vitamin metabolic process | 1 | PIAS4 | 75 | 0.8305783 |
| GO:BP | GO:0034728 | nucleosome organization | 2 | SMARCB1,NAP1L5 | 86 | 0.8317470 |
| GO:BP | GO:0031334 | positive regulation of protein-containing complex assembly | 1 | NAV3 | 161 | 0.8317470 |
| GO:BP | GO:0035239 | tube morphogenesis | 1 | LMO4 | 663 | 0.8317470 |
| GO:BP | GO:0006721 | terpenoid metabolic process | 1 | RDH13 | 49 | 0.8317470 |
| GO:BP | GO:0010633 | negative regulation of epithelial cell migration | 1 | MACIR | 53 | 0.8322566 |
| GO:BP | GO:2000241 | regulation of reproductive process | 2 | FZR1,SYDE1 | 126 | 0.8322566 |
| GO:BP | GO:0061333 | renal tubule morphogenesis | 1 | GZF1 | 62 | 0.8325581 |
| GO:BP | GO:0072028 | nephron morphogenesis | 1 | GZF1 | 62 | 0.8325581 |
| GO:BP | GO:0071346 | cellular response to type II interferon | 1 | RPS6KB1 | 68 | 0.8325581 |
| GO:BP | GO:0045665 | negative regulation of neuron differentiation | 1 | NEPRO | 44 | 0.8330262 |
| GO:BP | GO:0071887 | leukocyte apoptotic process | 2 | BAK1,TRAF3IP2 | 82 | 0.8333067 |
| GO:BP | GO:0002437 | inflammatory response to antigenic stimulus | 1 | MKRN2 | 38 | 0.8336997 |
| GO:BP | GO:0051785 | positive regulation of nuclear division | 1 | MAD1L1 | 38 | 0.8336997 |
| GO:BP | GO:0048813 | dendrite morphogenesis | 1 | PAFAH1B1 | 116 | 0.8338036 |
| GO:BP | GO:0010257 | NADH dehydrogenase complex assembly | 1 | LYRM2 | 57 | 0.8340004 |
| GO:BP | GO:0032981 | mitochondrial respiratory chain complex I assembly | 1 | LYRM2 | 57 | 0.8340004 |
| GO:BP | GO:0055080 | monoatomic cation homeostasis | 1 | ADORA1 | 410 | 0.8340004 |
| GO:BP | GO:0086065 | cell communication involved in cardiac conduction | 1 | SRI | 58 | 0.8343475 |
| GO:BP | GO:0030148 | sphingolipid biosynthetic process | 1 | CERS4 | 87 | 0.8360112 |
| GO:BP | GO:0032508 | DNA duplex unwinding | 1 | ASCC2 | 74 | 0.8375530 |
| GO:BP | GO:0045682 | regulation of epidermis development | 1 | PPARD | 44 | 0.8375530 |
| GO:BP | GO:0006220 | pyrimidine nucleotide metabolic process | 1 | UPRT | 47 | 0.8378423 |
| GO:BP | GO:0007259 | receptor signaling pathway via JAK-STAT | 2 | ARL2BP,STAT4 | 89 | 0.8378423 |
| GO:BP | GO:0050801 | monoatomic ion homeostasis | 1 | ADORA1 | 416 | 0.8380854 |
| GO:BP | GO:0006090 | pyruvate metabolic process | 1 | RPTOR | 97 | 0.8383407 |
| GO:BP | GO:0003208 | cardiac ventricle morphogenesis | 1 | PTCD2 | 62 | 0.8386493 |
| GO:BP | GO:0048255 | mRNA stabilization | 1 | TRAF3IP2 | 52 | 0.8424005 |
| GO:BP | GO:0098662 | inorganic cation transmembrane transport | 2 | PSEN2,PPP3CB | 538 | 0.8424641 |
| GO:BP | GO:0048513 | animal organ development | 1 | CPLANE2 | 2153 | 0.8454674 |
| GO:BP | GO:0051384 | response to glucocorticoid | 1 | RPS6KB1 | 82 | 0.8456557 |
| GO:BP | GO:0045600 | positive regulation of fat cell differentiation | 1 | PPARD | 50 | 0.8464593 |
| GO:BP | GO:0002274 | myeloid leukocyte activation | 1 | C12orf4 | 121 | 0.8464593 |
| GO:BP | GO:0043406 | positive regulation of MAP kinase activity | 1 | MAP2K7 | 82 | 0.8468165 |
| GO:BP | GO:0007204 | positive regulation of cytosolic calcium ion concentration | 1 | PML | 78 | 0.8468165 |
| GO:BP | GO:0042440 | pigment metabolic process | 1 | SRRD | 60 | 0.8468165 |
| GO:BP | GO:0021782 | glial cell development | 2 | PICK1,NSUN5 | 87 | 0.8468165 |
| GO:BP | GO:0044703 | multi-organism reproductive process | 4 | SYDE1,APOL2,PPARD,UPRT | 132 | 0.8476153 |
| GO:BP | GO:0022409 | positive regulation of cell-cell adhesion | 1 | KAT5 | 188 | 0.8476626 |
| GO:BP | GO:1902305 | regulation of sodium ion transmembrane transport | 1 | TMEM168 | 50 | 0.8483714 |
| GO:BP | GO:1902105 | regulation of leukocyte differentiation | 1 | KAT5 | 197 | 0.8483714 |
| GO:BP | GO:0030534 | adult behavior | 1 | PAFAH1B1 | 94 | 0.8503725 |
| GO:BP | GO:2000027 | regulation of animal organ morphogenesis | 1 | MKS1 | 102 | 0.8503725 |
| GO:BP | GO:0051937 | catecholamine transport | 1 | ADRA2C | 41 | 0.8505369 |
| GO:BP | GO:0001570 | vasculogenesis | 1 | MYO18B | 67 | 0.8519480 |
| GO:BP | GO:0031099 | regeneration | 3 | SRSF1,BAK1,PPARD | 142 | 0.8523711 |
| GO:BP | GO:0098655 | monoatomic cation transmembrane transport | 2 | PSEN2,PPP3CB | 555 | 0.8526728 |
| GO:BP | GO:0010811 | positive regulation of cell-substrate adhesion | 1 | RAC3 | 99 | 0.8526728 |
| GO:BP | GO:0045921 | positive regulation of exocytosis | 1 | RAB7A | 58 | 0.8526728 |
| GO:BP | GO:0097696 | receptor signaling pathway via STAT | 2 | ARL2BP,STAT4 | 92 | 0.8527269 |
| GO:BP | GO:1903533 | regulation of protein targeting | 1 | PARL | 67 | 0.8529915 |
| GO:BP | GO:0043367 | CD4-positive, alpha-beta T cell differentiation | 1 | STAT4 | 54 | 0.8544490 |
| GO:BP | GO:0050684 | regulation of mRNA processing | 2 | PTCD2,SRSF3 | 114 | 0.8545785 |
| GO:BP | GO:0051251 | positive regulation of lymphocyte activation | 1 | KAT5 | 200 | 0.8551788 |
| GO:BP | GO:0051606 | detection of stimulus | 1 | ADORA1 | 109 | 0.8551788 |
| GO:BP | GO:0019637 | organophosphate metabolic process | 2 | PIGC,IPMK | 775 | 0.8551788 |
| GO:BP | GO:0009620 | response to fungus | 1 | BAK1 | 22 | 0.8553643 |
| GO:BP | GO:0032388 | positive regulation of intracellular transport | 3 | RAN,EIPR1,RIOK2 | 174 | 0.8554160 |
| GO:BP | GO:0070372 | regulation of ERK1 and ERK2 cascade | 1 | GSTP1 | 192 | 0.8554160 |
| GO:BP | GO:0032392 | DNA geometric change | 1 | ASCC2 | 80 | 0.8555820 |
| GO:BP | GO:1902893 | regulation of miRNA transcription | 1 | PPARD | 58 | 0.8556018 |
| GO:BP | GO:0006163 | purine nucleotide metabolic process | 3 | RAN,PPCDC,EFL1 | 369 | 0.8559295 |
| GO:BP | GO:0042773 | ATP synthesis coupled electron transport | 1 | DGUOK | 84 | 0.8559295 |
| GO:BP | GO:0042775 | mitochondrial ATP synthesis coupled electron transport | 1 | DGUOK | 84 | 0.8559295 |
| GO:BP | GO:0001817 | regulation of cytokine production | 4 | KAT5,GSTP1,TBK1,NAV3 | 475 | 0.8572373 |
| GO:BP | GO:0030218 | erythrocyte differentiation | 2 | ANKRD54,UFL1 | 109 | 0.8574330 |
| GO:BP | GO:0065007 | biological regulation | 8 | WRAP73,PEX14,AGTRAP,PLEKHM2,CPLANE2,ARHGEF10L,ASAP3,PITHD1 | 8289 | 0.8574975 |
| GO:BP | GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1 | TERF2IP | 116 | 0.8577343 |
| GO:BP | GO:0061614 | miRNA transcription | 1 | PPARD | 59 | 0.8587798 |
| GO:BP | GO:0006811 | monoatomic ion transport | 3 | ADORA1,PSEN2,PPP3CB | 789 | 0.8587832 |
| GO:BP | GO:0002521 | leukocyte differentiation | 2 | PPP3CB,KAT5 | 387 | 0.8595601 |
| GO:BP | GO:0031326 | regulation of cellular biosynthetic process | 1 | PEX14 | 3797 | 0.8597609 |
| GO:BP | GO:0001816 | cytokine production | 4 | KAT5,GSTP1,TBK1,NAV3 | 479 | 0.8608455 |
| GO:BP | GO:0009889 | regulation of biosynthetic process | 1 | PEX14 | 3823 | 0.8618605 |
| GO:BP | GO:0008203 | cholesterol metabolic process | 2 | APOL2,PPARD | 99 | 0.8626706 |
| GO:BP | GO:0002757 | immune response-activating signaling pathway | 2 | TRIM3,TBK1 | 258 | 0.8626706 |
| GO:BP | GO:0048731 | system development | 3 | CPLANE2,LYPLA2,HDAC1 | 2881 | 0.8633952 |
| GO:BP | GO:0051881 | regulation of mitochondrial membrane potential | 1 | BAK1 | 63 | 0.8651823 |
| GO:BP | GO:0015698 | inorganic anion transport | 1 | SLC12A4 | 87 | 0.8651823 |
| GO:BP | GO:0006879 | intracellular iron ion homeostasis | 1 | SRI | 57 | 0.8654795 |
| GO:BP | GO:0006954 | inflammatory response | 3 | ADORA1,SCYL1,GSTP1 | 451 | 0.8654795 |
| GO:BP | GO:0014855 | striated muscle cell proliferation | 1 | PPARD | 58 | 0.8654795 |
| GO:BP | GO:0045069 | regulation of viral genome replication | 1 | TMEM39A | 64 | 0.8677347 |
| GO:BP | GO:0006820 | monoatomic anion transport | 1 | SLC12A4 | 92 | 0.8677347 |
| GO:BP | GO:0032874 | positive regulation of stress-activated MAPK cascade | 1 | MAP2K7 | 95 | 0.8677347 |
| GO:BP | GO:0042310 | vasoconstriction | 1 | ADRA2C | 51 | 0.8677347 |
| GO:BP | GO:1902075 | cellular response to salt | 1 | LIG4 | 144 | 0.8680981 |
| GO:BP | GO:0019222 | regulation of metabolic process | 105 | PEX14,PITHD1,HDAC1,RNF19B,MED8,LMO4,VPS72,LMNA,DUSP12,TIPRL,ADORA1,AIDA,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,BUB3,ZNF195,TRIM3,BDNF,ZNF408,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,GSTP1,ARAP1,EMSY,AQP11,MED17,ANKRD49,PAFAH1B2,MLF2,CDK4,TBK1,NAV3,CRY1,PRKAB1,TRIAP1,DIABLO,KMT5A,RAN,ZNF605,GTF2F2,ING1,GSKIP,BRF1,BAHD1,TRIP4,PML,WDR24,ERCC4,ARL2BP,E2F4,ZFP90,TERF2IP,CHMP1A,NXN,INCA1,ZNF287,NLE1,PEX12,CASC3,HEXIM1,OSBPL7,SPOP,SRSF1,RPS6KB1,INTS2,EIF4A3,RPTOR,CHMP6,RIOK3,IMPACT,MIER2,MOB3A,FZR1,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,SMG9,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,RAB1A,ZNF638 | 5002 | 0.8684004 |
| GO:BP | GO:0042246 | tissue regeneration | 1 | PPARD | 54 | 0.8685333 |
| GO:BP | GO:0009060 | aerobic respiration | 2 | TEFM,DGUOK | 171 | 0.8690202 |
| GO:BP | GO:0002699 | positive regulation of immune effector process | 1 | C12orf4 | 135 | 0.8690202 |
| GO:BP | GO:0042130 | negative regulation of T cell proliferation | 1 | MAD1L1 | 38 | 0.8701370 |
| GO:BP | GO:0061448 | connective tissue development | 2 | CDK4,HSD17B1 | 212 | 0.8702583 |
| GO:BP | GO:0010822 | positive regulation of mitochondrion organization | 1 | BAK1 | 66 | 0.8708248 |
| GO:BP | GO:0070304 | positive regulation of stress-activated protein kinase signaling cascade | 1 | MAP2K7 | 97 | 0.8710201 |
| GO:BP | GO:0048640 | negative regulation of developmental growth | 1 | BCL11A | 94 | 0.8719456 |
| GO:BP | GO:0034341 | response to type II interferon | 1 | RPS6KB1 | 82 | 0.8721239 |
| GO:BP | GO:0006986 | response to unfolded protein | 2 | BAK1,UFL1 | 126 | 0.8721239 |
| GO:BP | GO:0070371 | ERK1 and ERK2 cascade | 1 | GSTP1 | 211 | 0.8721746 |
| GO:BP | GO:0043489 | RNA stabilization | 1 | TRAF3IP2 | 61 | 0.8723244 |
| GO:BP | GO:0070192 | chromosome organization involved in meiotic cell cycle | 1 | SMC2 | 35 | 0.8737581 |
| GO:BP | GO:1901615 | organic hydroxy compound metabolic process | 1 | IPMK | 375 | 0.8742545 |
| GO:BP | GO:0006635 | fatty acid beta-oxidation | 1 | PPARD | 68 | 0.8743005 |
| GO:BP | GO:0001936 | regulation of endothelial cell proliferation | 1 | RPTOR | 102 | 0.8753960 |
| GO:BP | GO:0046434 | organophosphate catabolic process | 1 | GDPD1 | 113 | 0.8753960 |
| GO:BP | GO:1902373 | negative regulation of mRNA catabolic process | 1 | TRAF3IP2 | 59 | 0.8754915 |
| GO:BP | GO:0071103 | DNA conformation change | 1 | ASCC2 | 87 | 0.8757185 |
| GO:BP | GO:0098660 | inorganic ion transmembrane transport | 2 | PSEN2,PPP3CB | 583 | 0.8758883 |
| GO:BP | GO:0060993 | kidney morphogenesis | 1 | GZF1 | 73 | 0.8758883 |
| GO:BP | GO:0001657 | ureteric bud development | 1 | GZF1 | 75 | 0.8758883 |
| GO:BP | GO:0061351 | neural precursor cell proliferation | 1 | PAFAH1B1 | 122 | 0.8759322 |
| GO:BP | GO:0016079 | synaptic vesicle exocytosis | 1 | DNAJC5 | 74 | 0.8759322 |
| GO:BP | GO:0097009 | energy homeostasis | 1 | PPARD | 59 | 0.8763023 |
| GO:BP | GO:0031323 | regulation of cellular metabolic process | 96 | PEX14,PITHD1,HDAC1,MED8,LMO4,VPS72,LMNA,DUSP12,TIPRL,ADORA1,AIDA,JMJD4,SUV39H2,ECD,PPP3CB,ANKRD1,BLOC1S2,ZNF195,TRIM3,BDNF,ZNF408,CLP1,POLR2G,SPINDOC,KAT5,BRMS1,RBM14,PPP1CA,GSTP1,EMSY,MED17,ANKRD49,PAFAH1B2,MLF2,CDK4,TBK1,NAV3,CRY1,PRKAB1,TRIAP1,KMT5A,RAN,ZNF605,GTF2F2,ING1,GSKIP,BRF1,BAHD1,TRIP4,PML,WDR24,ERCC4,ARL2BP,E2F4,ZFP90,TERF2IP,CHMP1A,INCA1,ZNF287,CASC3,HEXIM1,OSBPL7,SRSF1,RPS6KB1,INTS2,EIF4A3,RPTOR,CHMP6,RIOK3,IMPACT,MIER2,MOB3A,FZR1,PIAS4,MAP2K7,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,SERTAD1,SMG9,ZNF230,ZNF226,ZNF432,ZNF480,ZNF579,ZNF548,ZNF587B,ZNF324,HNRNPLL,MTA3,BCL11A,RAB1A,ZNF638 | 4568 | 0.8768026 |
| GO:BP | GO:0034101 | erythrocyte homeostasis | 2 | ANKRD54,UFL1 | 116 | 0.8776361 |
| GO:BP | GO:0072163 | mesonephric epithelium development | 1 | GZF1 | 76 | 0.8776361 |
| GO:BP | GO:0072164 | mesonephric tubule development | 1 | GZF1 | 76 | 0.8776361 |
| GO:BP | GO:0050868 | negative regulation of T cell activation | 2 | MAD1L1,PAG1 | 67 | 0.8780451 |
| GO:BP | GO:0015980 | energy derivation by oxidation of organic compounds | 1 | PPP1CA | 290 | 0.8781755 |
| GO:BP | GO:0002285 | lymphocyte activation involved in immune response | 1 | LIG4 | 116 | 0.8782525 |
| GO:BP | GO:0051240 | positive regulation of multicellular organismal process | 1 | HDAC1 | 1102 | 0.8782525 |
| GO:BP | GO:0070918 | regulatory ncRNA processing | 1 | SRSF3 | 58 | 0.8795178 |
| GO:BP | GO:1903037 | regulation of leukocyte cell-cell adhesion | 1 | KAT5 | 210 | 0.8798033 |
| GO:BP | GO:0001822 | kidney development | 1 | AQP11 | 245 | 0.8800496 |
| GO:BP | GO:0002764 | immune response-regulating signaling pathway | 2 | TRIM3,TBK1 | 269 | 0.8805792 |
| GO:BP | GO:0006493 | protein O-linked glycosylation | 1 | SLC35C2 | 75 | 0.8817864 |
| GO:BP | GO:0002832 | negative regulation of response to biotic stimulus | 1 | RIOK3 | 102 | 0.8828606 |
| GO:BP | GO:1902652 | secondary alcohol metabolic process | 2 | APOL2,PPARD | 106 | 0.8832463 |
| GO:BP | GO:0002684 | positive regulation of immune system process | 5 | TRIM3,KAT5,RBM14,C12orf4,TBK1 | 609 | 0.8832463 |
| GO:BP | GO:0001775 | cell activation | 1 | LMO4 | 655 | 0.8832463 |
| GO:BP | GO:0051239 | regulation of multicellular organismal process | 2 | PITHD1,HDAC1 | 2048 | 0.8832463 |
| GO:BP | GO:0031016 | pancreas development | 1 | BAK1 | 51 | 0.8832479 |
| GO:BP | GO:1904019 | epithelial cell apoptotic process | 1 | PIAS4 | 101 | 0.8832959 |
| GO:BP | GO:0002696 | positive regulation of leukocyte activation | 1 | KAT5 | 222 | 0.8834459 |
| GO:BP | GO:0032760 | positive regulation of tumor necrosis factor production | 1 | ARFGEF2 | 54 | 0.8837227 |
| GO:BP | GO:0048568 | embryonic organ development | 4 | CLUAP1,MKS1,EIF4A3,SLC39A3 | 314 | 0.8837227 |
| GO:BP | GO:0050863 | regulation of T cell activation | 1 | KAT5 | 215 | 0.8837227 |
| GO:BP | GO:0046849 | bone remodeling | 1 | RAB7A | 60 | 0.8838140 |
| GO:BP | GO:0001823 | mesonephros development | 1 | GZF1 | 77 | 0.8849611 |
| GO:BP | GO:0001764 | neuron migration | 1 | PAFAH1B1 | 133 | 0.8862537 |
| GO:BP | GO:0002440 | production of molecular mediator of immune response | 1 | LIG4 | 133 | 0.8868736 |
| GO:BP | GO:0007267 | cell-cell signaling | 1 | HDAC1 | 1149 | 0.8885064 |
| GO:BP | GO:0002532 | production of molecular mediator involved in inflammatory response | 1 | MACIR | 52 | 0.8912143 |
| GO:BP | GO:0007584 | response to nutrient | 1 | RPS6KB1 | 107 | 0.8917484 |
| GO:BP | GO:0019221 | cytokine-mediated signaling pathway | 2 | GSTP1,TBK1 | 280 | 0.8927150 |
| GO:BP | GO:0070936 | protein K48-linked ubiquitination | 1 | RNF216 | 77 | 0.8930452 |
| GO:BP | GO:0050867 | positive regulation of cell activation | 1 | KAT5 | 227 | 0.8930452 |
| GO:BP | GO:1903557 | positive regulation of tumor necrosis factor superfamily cytokine production | 1 | ARFGEF2 | 56 | 0.8933928 |
| GO:BP | GO:0002181 | cytoplasmic translation | 2 | IMPACT,CPEB4 | 150 | 0.8951973 |
| GO:BP | GO:0060021 | roof of mouth development | 1 | BBS7 | 71 | 0.8970665 |
| GO:BP | GO:0022904 | respiratory electron transport chain | 1 | DGUOK | 106 | 0.9011816 |
| GO:BP | GO:0021700 | developmental maturation | 4 | RAC3,AP1M1,BCL11A,PICK1 | 213 | 0.9017099 |
| GO:BP | GO:0030154 | cell differentiation | 3 | PITHD1,LYPLA2,HDAC1 | 2938 | 0.9017099 |
| GO:BP | GO:0048869 | cellular developmental process | 3 | PITHD1,LYPLA2,HDAC1 | 2939 | 0.9017099 |
| GO:BP | GO:0009117 | nucleotide metabolic process | 3 | RAN,PPCDC,EFL1 | 422 | 0.9022763 |
| GO:BP | GO:0034329 | cell junction assembly | 1 | BDNF | 346 | 0.9022763 |
| GO:BP | GO:0010975 | regulation of neuron projection development | 1 | BDNF | 373 | 0.9029490 |
| GO:BP | GO:0007159 | leukocyte cell-cell adhesion | 1 | KAT5 | 233 | 0.9029490 |
| GO:BP | GO:0009615 | response to virus | 8 | TBK1,PML,RIOK3,DHX16,TRAF3IP2,RNF216,TRIM35,ZDHHC12 | 294 | 0.9030039 |
| GO:BP | GO:0071695 | anatomical structure maturation | 3 | RAC3,BCL11A,PICK1 | 157 | 0.9030039 |
| GO:BP | GO:1903038 | negative regulation of leukocyte cell-cell adhesion | 2 | MAD1L1,PAG1 | 74 | 0.9039303 |
| GO:BP | GO:0034655 | nucleobase-containing compound catabolic process | 4 | POLR2G,CASC3,EIF4A3,SMG9 | 367 | 0.9049336 |
| GO:BP | GO:0009152 | purine ribonucleotide biosynthetic process | 1 | PPCDC | 179 | 0.9055084 |
| GO:BP | GO:0035710 | CD4-positive, alpha-beta T cell activation | 1 | STAT4 | 68 | 0.9055084 |
| GO:BP | GO:0051279 | regulation of release of sequestered calcium ion into cytosol | 1 | SRI | 60 | 0.9055776 |
| GO:BP | GO:0048856 | anatomical structure development | 3 | CPLANE2,PITHD1,LYPLA2 | 4094 | 0.9056881 |
| GO:BP | GO:0006720 | isoprenoid metabolic process | 1 | RDH13 | 84 | 0.9057203 |
| GO:BP | GO:0007272 | ensheathment of neurons | 2 | PPARD,NSUN5 | 115 | 0.9057203 |
| GO:BP | GO:0008366 | axon ensheathment | 2 | PPARD,NSUN5 | 115 | 0.9057203 |
| GO:BP | GO:0060249 | anatomical structure homeostasis | 2 | MKS1,RAC3 | 179 | 0.9060972 |
| GO:BP | GO:0001894 | tissue homeostasis | 2 | MKS1,RAC3 | 179 | 0.9060972 |
| GO:BP | GO:0006753 | nucleoside phosphate metabolic process | 3 | RAN,PPCDC,EFL1 | 428 | 0.9068392 |
| GO:BP | GO:0034220 | monoatomic ion transmembrane transport | 2 | PSEN2,PPP3CB | 651 | 0.9071950 |
| GO:BP | GO:0001935 | endothelial cell proliferation | 1 | RPTOR | 120 | 0.9086374 |
| GO:BP | GO:0033273 | response to vitamin | 1 | PPARD | 63 | 0.9098589 |
| GO:BP | GO:0002286 | T cell activation involved in immune response | 1 | STAT4 | 59 | 0.9098589 |
| GO:BP | GO:0050672 | negative regulation of lymphocyte proliferation | 1 | MAD1L1 | 46 | 0.9102076 |
| GO:BP | GO:0042445 | hormone metabolic process | 2 | HSD17B1,RDH13 | 132 | 0.9107855 |
| GO:BP | GO:0032945 | negative regulation of mononuclear cell proliferation | 1 | MAD1L1 | 46 | 0.9128979 |
| GO:BP | GO:0030183 | B cell differentiation | 2 | BAK1,TRAF3IP2 | 91 | 0.9128979 |
| GO:BP | GO:0046632 | alpha-beta T cell differentiation | 1 | STAT4 | 71 | 0.9132833 |
| GO:BP | GO:0070972 | protein localization to endoplasmic reticulum | 2 | UBAC2,SRP68 | 81 | 0.9136277 |
| GO:BP | GO:0016070 | RNA metabolic process | 1 | PEX14 | 3634 | 0.9140750 |
| GO:BP | GO:0008543 | fibroblast growth factor receptor signaling pathway | 1 | RAB14 | 59 | 0.9151030 |
| GO:BP | GO:0002064 | epithelial cell development | 1 | E2F4 | 155 | 0.9161525 |
| GO:BP | GO:0006626 | protein targeting to mitochondrion | 1 | PARL | 100 | 0.9162828 |
| GO:BP | GO:0019217 | regulation of fatty acid metabolic process | 1 | PPARD | 68 | 0.9162828 |
| GO:BP | GO:0015718 | monocarboxylic acid transport | 1 | RPS6KB1 | 91 | 0.9166150 |
| GO:BP | GO:0050808 | synapse organization | 1 | BDNF | 372 | 0.9171072 |
| GO:BP | GO:0016358 | dendrite development | 2 | PAFAH1B1,BCL11A | 193 | 0.9171072 |
| GO:BP | GO:0035418 | protein localization to synapse | 1 | ZDHHC12 | 68 | 0.9175274 |
| GO:BP | GO:0002028 | regulation of sodium ion transport | 1 | TMEM168 | 71 | 0.9175274 |
| GO:BP | GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction | 2 | RPS6KB1,MKRN2 | 144 | 0.9175274 |
| GO:BP | GO:0009260 | ribonucleotide biosynthetic process | 1 | PPCDC | 192 | 0.9175274 |
| GO:BP | GO:1990778 | protein localization to cell periphery | 2 | TTC8,RABEP1 | 301 | 0.9175274 |
| GO:BP | GO:0006939 | smooth muscle contraction | 1 | ADRA2C | 71 | 0.9178542 |
| GO:BP | GO:0071805 | potassium ion transmembrane transport | 1 | SLC12A4 | 129 | 0.9178542 |
| GO:BP | GO:0009791 | post-embryonic development | 1 | BAK1 | 76 | 0.9213593 |
| GO:BP | GO:0042742 | defense response to bacterium | 1 | TBK1 | 98 | 0.9224403 |
| GO:BP | GO:0002694 | regulation of leukocyte activation | 2 | KAT5,C12orf4 | 346 | 0.9231329 |
| GO:BP | GO:0046390 | ribose phosphate biosynthetic process | 1 | PPCDC | 199 | 0.9237387 |
| GO:BP | GO:0046700 | heterocycle catabolic process | 1 | POLR2G | 389 | 0.9237387 |
| GO:BP | GO:0044270 | cellular nitrogen compound catabolic process | 1 | POLR2G | 386 | 0.9237387 |
| GO:BP | GO:0032147 | activation of protein kinase activity | 1 | ADRA2C | 82 | 0.9237387 |
| GO:BP | GO:0006029 | proteoglycan metabolic process | 1 | PPARD | 77 | 0.9237387 |
| GO:BP | GO:0046649 | lymphocyte activation | 2 | PPP3CB,KAT5 | 469 | 0.9255435 |
| GO:BP | GO:0032501 | multicellular organismal process | 4 | AGTRAP,CPLANE2,PITHD1,LYPLA2 | 4801 | 0.9294253 |
| GO:BP | GO:0042542 | response to hydrogen peroxide | 1 | BAK1 | 85 | 0.9294492 |
| GO:BP | GO:0045807 | positive regulation of endocytosis | 2 | PICK1,PPP3CC | 104 | 0.9294492 |
| GO:BP | GO:0045333 | cellular respiration | 2 | TEFM,DGUOK | 214 | 0.9309509 |
| GO:BP | GO:0072527 | pyrimidine-containing compound metabolic process | 1 | UPRT | 69 | 0.9313352 |
| GO:BP | GO:0032963 | collagen metabolic process | 1 | PPARD | 72 | 0.9315014 |
| GO:BP | GO:0045132 | meiotic chromosome segregation | 1 | SMC2 | 51 | 0.9315014 |
| GO:BP | GO:0019439 | aromatic compound catabolic process | 1 | POLR2G | 396 | 0.9315014 |
| GO:BP | GO:0050768 | negative regulation of neurogenesis | 1 | BCL11A | 113 | 0.9320298 |
| GO:BP | GO:0006164 | purine nucleotide biosynthetic process | 3 | PPCDC,DGUOK,PAICS | 210 | 0.9328104 |
| GO:BP | GO:0022407 | regulation of cell-cell adhesion | 1 | KAT5 | 292 | 0.9328104 |
| GO:BP | GO:0045785 | positive regulation of cell adhesion | 1 | KAT5 | 319 | 0.9328104 |
| GO:BP | GO:0009952 | anterior/posterior pattern specification | 1 | NLE1 | 125 | 0.9328104 |
| GO:BP | GO:1903312 | negative regulation of mRNA metabolic process | 1 | TRAF3IP2 | 84 | 0.9328104 |
| GO:BP | GO:0042113 | B cell activation | 1 | LIG4 | 169 | 0.9328104 |
| GO:BP | GO:0090304 | nucleic acid metabolic process | 1 | PEX14 | 4081 | 0.9336572 |
| GO:BP | GO:0061337 | cardiac conduction | 1 | SRI | 88 | 0.9339387 |
| GO:BP | GO:0032465 | regulation of cytokinesis | 1 | KLHL9 | 77 | 0.9351641 |
| GO:BP | GO:0007600 | sensory perception | 1 | ADORA1 | 259 | 0.9361107 |
| GO:BP | GO:0060349 | bone morphogenesis | 1 | RAB23 | 74 | 0.9365062 |
| GO:BP | GO:0006334 | nucleosome assembly | 1 | NAP1L5 | 69 | 0.9370855 |
| GO:BP | GO:0000395 | mRNA 5’-splice site recognition | 1 | SRSF1 | 9 | 0.9370855 |
| GO:BP | GO:0002573 | myeloid leukocyte differentiation | 1 | PAFAH1B1 | 154 | 0.9376595 |
| GO:BP | GO:0042180 | cellular ketone metabolic process | 1 | HSD17B1 | 161 | 0.9384102 |
| GO:BP | GO:0051961 | negative regulation of nervous system development | 1 | BCL11A | 119 | 0.9393474 |
| GO:BP | GO:1901361 | organic cyclic compound catabolic process | 1 | POLR2G | 413 | 0.9403652 |
| GO:BP | GO:0032502 | developmental process | 3 | CPLANE2,PITHD1,LYPLA2 | 4441 | 0.9404314 |
| GO:BP | GO:0009062 | fatty acid catabolic process | 1 | PPARD | 89 | 0.9404314 |
| GO:BP | GO:0051249 | regulation of lymphocyte activation | 1 | KAT5 | 296 | 0.9406343 |
| GO:BP | GO:0072522 | purine-containing compound biosynthetic process | 3 | PPCDC,DGUOK,PAICS | 219 | 0.9409086 |
| GO:BP | GO:0051250 | negative regulation of lymphocyte activation | 2 | MAD1L1,PAG1 | 89 | 0.9409086 |
| GO:BP | GO:0002027 | regulation of heart rate | 1 | SRI | 85 | 0.9421446 |
| GO:BP | GO:0097529 | myeloid leukocyte migration | 1 | PAFAH1B1 | 118 | 0.9421446 |
| GO:BP | GO:0019395 | fatty acid oxidation | 1 | PPARD | 91 | 0.9429240 |
| GO:BP | GO:0072655 | establishment of protein localization to mitochondrion | 1 | PARL | 117 | 0.9429240 |
| GO:BP | GO:0001944 | vasculature development | 1 | PPP3CB | 562 | 0.9431633 |
| GO:BP | GO:0048024 | regulation of mRNA splicing, via spliceosome | 1 | SRSF3 | 92 | 0.9431633 |
| GO:BP | GO:0007029 | endoplasmic reticulum organization | 1 | REEP4 | 91 | 0.9439236 |
| GO:BP | GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 2 | BDNF,CDK4 | 471 | 0.9463732 |
| GO:BP | GO:0072659 | protein localization to plasma membrane | 3 | TTC8,TMEM150A,RAB7A | 250 | 0.9472540 |
| GO:BP | GO:0007269 | neurotransmitter secretion | 1 | DNAJC5 | 105 | 0.9488010 |
| GO:BP | GO:0099643 | signal release from synapse | 1 | DNAJC5 | 105 | 0.9488010 |
| GO:BP | GO:0045765 | regulation of angiogenesis | 1 | PML | 200 | 0.9504101 |
| GO:BP | GO:0034440 | lipid oxidation | 1 | PPARD | 92 | 0.9521375 |
| GO:BP | GO:1901342 | regulation of vasculature development | 1 | PML | 202 | 0.9521375 |
| GO:BP | GO:0070585 | protein localization to mitochondrion | 1 | PARL | 123 | 0.9535316 |
| GO:BP | GO:0001667 | ameboidal-type cell migration | 3 | PML,PAFAH1B1,SYDE1 | 358 | 0.9540657 |
| GO:BP | GO:0016579 | protein deubiquitination | 1 | PSMD14 | 127 | 0.9563269 |
| GO:BP | GO:0006376 | mRNA splice site recognition | 1 | SRSF1 | 33 | 0.9566216 |
| GO:BP | GO:0010810 | regulation of cell-substrate adhesion | 1 | RAC3 | 171 | 0.9577183 |
| GO:BP | GO:0030168 | platelet activation | 1 | ADRA2C | 90 | 0.9581046 |
| GO:BP | GO:0006091 | generation of precursor metabolites and energy | 1 | PPP1CA | 425 | 0.9581046 |
| GO:BP | GO:0051091 | positive regulation of DNA-binding transcription factor activity | 1 | TERF2IP | 198 | 0.9592021 |
| GO:BP | GO:0030258 | lipid modification | 2 | SACM1L,PPARD | 157 | 0.9596930 |
| GO:BP | GO:0009165 | nucleotide biosynthetic process | 1 | PPCDC | 242 | 0.9601433 |
| GO:BP | GO:0046660 | female sex differentiation | 1 | BAK1 | 91 | 0.9603410 |
| GO:BP | GO:1901293 | nucleoside phosphate biosynthetic process | 1 | PPCDC | 243 | 0.9609112 |
| GO:BP | GO:0006397 | mRNA processing | 7 | SDE2,ECD,FRA10AC1,CLP1,RBM14,PCF11,SRSF8 | 455 | 0.9618794 |
| GO:BP | GO:0048565 | digestive tract development | 1 | BBS7 | 92 | 0.9618794 |
| GO:BP | GO:0044344 | cellular response to fibroblast growth factor stimulus | 1 | RAB14 | 81 | 0.9618794 |
| GO:BP | GO:0045321 | leukocyte activation | 3 | PPP3CB,KAT5,C12orf4 | 556 | 0.9618794 |
| GO:BP | GO:1903900 | regulation of viral life cycle | 1 | TMEM39A | 101 | 0.9618794 |
| GO:BP | GO:0022900 | electron transport chain | 1 | DGUOK | 144 | 0.9618794 |
| GO:BP | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 1 | MAP2K7 | 120 | 0.9618794 |
| GO:BP | GO:0016441 | post-transcriptional gene silencing | 1 | CLP1 | 72 | 0.9645307 |
| GO:BP | GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 1 | ADRA2C | 71 | 0.9665274 |
| GO:BP | GO:1902414 | protein localization to cell junction | 1 | ZDHHC12 | 94 | 0.9679875 |
| GO:BP | GO:0016071 | mRNA metabolic process | 8 | SDE2,ECD,FRA10AC1,CLP1,POLR2G,RBM14,PCF11,SRSF8 | 673 | 0.9686060 |
| GO:BP | GO:0022603 | regulation of anatomical structure morphogenesis | 2 | BDNF,ARAP1 | 679 | 0.9693059 |
| GO:BP | GO:0045598 | regulation of fat cell differentiation | 1 | PPARD | 100 | 0.9693971 |
| GO:BP | GO:0070646 | protein modification by small protein removal | 1 | PSMD14 | 145 | 0.9693971 |
| GO:BP | GO:0045596 | negative regulation of cell differentiation | 1 | BDNF | 469 | 0.9693971 |
| GO:BP | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1 | SRP68 | 32 | 0.9693971 |
| GO:BP | GO:0046631 | alpha-beta T cell activation | 1 | STAT4 | 93 | 0.9693971 |
| GO:BP | GO:0072329 | monocarboxylic acid catabolic process | 1 | PPARD | 105 | 0.9697609 |
| GO:BP | GO:0006807 | nitrogen compound metabolic process | 2 | ICMT,PEX14 | 7500 | 0.9697609 |
| GO:BP | GO:0010565 | regulation of cellular ketone metabolic process | 1 | PPARD | 101 | 0.9702665 |
| GO:BP | GO:0022408 | negative regulation of cell-cell adhesion | 2 | MAD1L1,PAG1 | 115 | 0.9702665 |
| GO:BP | GO:0071774 | response to fibroblast growth factor | 1 | RAB14 | 85 | 0.9702665 |
| GO:BP | GO:0006613 | cotranslational protein targeting to membrane | 1 | SRP68 | 37 | 0.9710629 |
| GO:BP | GO:0055123 | digestive system development | 1 | BBS7 | 100 | 0.9719717 |
| GO:BP | GO:1902074 | response to salt | 1 | LIG4 | 261 | 0.9724907 |
| GO:BP | GO:0002695 | negative regulation of leukocyte activation | 2 | MAD1L1,PAG1 | 103 | 0.9724916 |
| GO:BP | GO:0022613 | ribonucleoprotein complex biogenesis | 1 | NSUN4 | 469 | 0.9735397 |
| GO:BP | GO:0031047 | regulatory ncRNA-mediated gene silencing | 1 | CLP1 | 121 | 0.9760951 |
| GO:BP | GO:0035270 | endocrine system development | 1 | BAK1 | 85 | 0.9767263 |
| GO:BP | GO:0043170 | macromolecule metabolic process | 2 | ICMT,PEX14 | 7153 | 0.9776408 |
| GO:BP | GO:0008380 | RNA splicing | 5 | SDE2,ECD,FRA10AC1,CLP1,RBM14 | 430 | 0.9776666 |
| GO:BP | GO:0050877 | nervous system process | 3 | ADORA1,PPP3CB,BDNF | 627 | 0.9777195 |
| GO:BP | GO:0010467 | gene expression | 1 | PEX14 | 4798 | 0.9777195 |
| GO:BP | GO:0045047 | protein targeting to ER | 1 | SRP68 | 52 | 0.9777195 |
| GO:BP | GO:0072599 | establishment of protein localization to endoplasmic reticulum | 1 | SRP68 | 56 | 0.9790879 |
| GO:BP | GO:0051209 | release of sequestered calcium ion into cytosol | 1 | SRI | 90 | 0.9790879 |
| GO:BP | GO:0051283 | negative regulation of sequestering of calcium ion | 1 | SRI | 91 | 0.9797380 |
| GO:BP | GO:0042592 | homeostatic process | 5 | ADORA1,PPP3CB,KAT5,GSTP1,AQP11 | 1189 | 0.9799754 |
| GO:BP | GO:0034330 | cell junction organization | 1 | BDNF | 585 | 0.9803175 |
| GO:BP | GO:0051282 | regulation of sequestering of calcium ion | 1 | SRI | 93 | 0.9807406 |
| GO:BP | GO:0001505 | regulation of neurotransmitter levels | 1 | DNAJC5 | 132 | 0.9807406 |
| GO:BP | GO:0042060 | wound healing | 2 | CHMP1A,CHMP6 | 304 | 0.9822143 |
| GO:BP | GO:0001819 | positive regulation of cytokine production | 1 | TBK1 | 283 | 0.9824052 |
| GO:BP | GO:0051208 | sequestering of calcium ion | 1 | SRI | 97 | 0.9828422 |
| GO:BP | GO:0001890 | placenta development | 1 | PPARD | 116 | 0.9828422 |
| GO:BP | GO:0001508 | action potential | 1 | SRI | 106 | 0.9828422 |
| GO:BP | GO:0042552 | myelination | 1 | NSUN5 | 113 | 0.9839542 |
| GO:BP | GO:0050866 | negative regulation of cell activation | 2 | MAD1L1,PAG1 | 121 | 0.9841375 |
| GO:BP | GO:1901136 | carbohydrate derivative catabolic process | 1 | GNPDA2 | 137 | 0.9842498 |
| GO:BP | GO:0009059 | macromolecule biosynthetic process | 1 | PEX14 | 5214 | 0.9855186 |
| GO:BP | GO:0031589 | cell-substrate adhesion | 2 | RAC3,RAB1A | 271 | 0.9861253 |
| GO:BP | GO:0008154 | actin polymerization or depolymerization | 1 | SPATC1L | 157 | 0.9862142 |
| GO:BP | GO:0044238 | primary metabolic process | 2 | ICMT,PEX14 | 7855 | 0.9866429 |
| GO:BP | GO:0006836 | neurotransmitter transport | 1 | DNAJC5 | 141 | 0.9879731 |
| GO:BP | GO:0009611 | response to wounding | 3 | CHMP1A,CHMP6,MAP2K7 | 394 | 0.9881818 |
| GO:BP | GO:0007608 | sensory perception of smell | 1 | TTC8 | 15 | 0.9888130 |
| GO:BP | GO:0016054 | organic acid catabolic process | 2 | GNPDA2,PPARD | 187 | 0.9901511 |
| GO:BP | GO:0030155 | regulation of cell adhesion | 1 | KAT5 | 535 | 0.9901511 |
| GO:BP | GO:0046395 | carboxylic acid catabolic process | 2 | GNPDA2,PPARD | 187 | 0.9901511 |
| GO:BP | GO:1902600 | proton transmembrane transport | 1 | PPARD | 119 | 0.9912081 |
| GO:BP | GO:0006261 | DNA-templated DNA replication | 1 | ORC5 | 150 | 0.9927772 |
| GO:BP | GO:0044237 | cellular metabolic process | 2 | ICMT,PEX14 | 7633 | 0.9931985 |
| GO:BP | GO:0000245 | spliceosomal complex assembly | 1 | SRSF1 | 76 | 0.9953631 |
| GO:BP | GO:0006814 | sodium ion transport | 2 | MFSD4B,TMEM168 | 158 | 0.9954914 |
| GO:BP | GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 1 | MAP2K7 | 165 | 0.9957526 |
| GO:BP | GO:0044249 | cellular biosynthetic process | 1 | PEX14 | 5878 | 0.9963829 |
| GO:BP | GO:0010721 | negative regulation of cell development | 1 | BCL11A | 190 | 0.9964051 |
| GO:BP | GO:0000398 | mRNA splicing, via spliceosome | 2 | SDE2,FRA10AC1 | 292 | 0.9964051 |
| GO:BP | GO:0042129 | regulation of T cell proliferation | 1 | MAD1L1 | 94 | 0.9964051 |
| GO:BP | GO:0000375 | RNA splicing, via transesterification reactions | 2 | SDE2,FRA10AC1 | 296 | 0.9964051 |
| GO:BP | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 2 | SDE2,FRA10AC1 | 292 | 0.9964051 |
| GO:BP | GO:1901576 | organic substance biosynthetic process | 1 | PEX14 | 5940 | 0.9964051 |
| GO:BP | GO:0009058 | biosynthetic process | 1 | PEX14 | 5977 | 0.9964051 |
| GO:BP | GO:0007606 | sensory perception of chemical stimulus | 1 | TTC8 | 29 | 0.9967863 |
| GO:BP | GO:0035725 | sodium ion transmembrane transport | 1 | TMEM168 | 112 | 0.9976287 |
| GO:BP | GO:0007601 | visual perception | 1 | BBS7 | 97 | 0.9980868 |
| GO:BP | GO:0007596 | blood coagulation | 1 | ADRA2C | 150 | 0.9983282 |
| GO:BP | GO:0050953 | sensory perception of light stimulus | 1 | BBS7 | 98 | 0.9983282 |
| GO:BP | GO:0050817 | coagulation | 1 | ADRA2C | 153 | 0.9990247 |
| GO:BP | GO:0007599 | hemostasis | 1 | ADRA2C | 154 | 0.9990247 |
| GO:BP | GO:0051302 | regulation of cell division | 1 | KLHL9 | 140 | 0.9990247 |
| GO:BP | GO:0010632 | regulation of epithelial cell migration | 1 | MACIR | 195 | 0.9991636 |
| GO:BP | GO:0010631 | epithelial cell migration | 2 | MACIR,PPARD | 253 | 0.9991636 |
| GO:BP | GO:0090132 | epithelium migration | 2 | MACIR,PPARD | 253 | 0.9991636 |
| GO:BP | GO:0001525 | angiogenesis | 1 | PML | 389 | 0.9991636 |
| GO:BP | GO:0090130 | tissue migration | 2 | MACIR,PPARD | 257 | 0.9992281 |
| GO:BP | GO:0035194 | regulatory ncRNA-mediated post-transcriptional gene silencing | 1 | RAN | 64 | 0.9992281 |
| GO:BP | GO:0035195 | miRNA-mediated post-transcriptional gene silencing | 1 | RAN | 59 | 0.9992281 |
| GO:BP | GO:0007162 | negative regulation of cell adhesion | 2 | MAD1L1,PAG1 | 191 | 0.9998629 |
| GO:BP | GO:0000365 | mRNA trans splicing, via spliceosome | 1 | ZNF638 | 7 | 1.0000000 |
| GO:BP | GO:0006396 | RNA processing | 5 | NSUN4,SDE2,ECD,FRA10AC1,NPM3 | 988 | 1.0000000 |
| GO:BP | GO:0032944 | regulation of mononuclear cell proliferation | 1 | MAD1L1 | 128 | 1.0000000 |
| GO:BP | GO:2000147 | positive regulation of cell motility | 2 | RPS6KB1,SYDE1 | 422 | 1.0000000 |
| GO:BP | GO:0009987 | cellular process | 1 | WRAP73 | 11490 | 1.0000000 |
| GO:BP | GO:0071826 | protein-RNA complex organization | 1 | CLP1 | 216 | 1.0000000 |
| GO:BP | GO:0071704 | organic substance metabolic process | 2 | ICMT,PEX14 | 8244 | 1.0000000 |
| GO:BP | GO:0040017 | positive regulation of locomotion | 2 | RPS6KB1,SYDE1 | 430 | 1.0000000 |
| GO:BP | GO:0006959 | humoral immune response | 1 | TRAF3IP2 | 82 | 1.0000000 |
| GO:BP | GO:0030335 | positive regulation of cell migration | 2 | RPS6KB1,SYDE1 | 408 | 1.0000000 |
| GO:BP | GO:0000353 | formation of quadruple SL/U4/U5/U6 snRNP | 1 | ZNF638 | 7 | 1.0000000 |
| GO:BP | GO:0007548 | sex differentiation | 1 | BAK1 | 193 | 1.0000000 |
| GO:BP | GO:0022618 | protein-RNA complex assembly | 1 | CLP1 | 208 | 1.0000000 |
| GO:BP | GO:0008150 | biological_process | 1 | WRAP73 | 12110 | 1.0000000 |
| GO:BP | GO:0008152 | metabolic process | 1 | ICMT | 8593 | 1.0000000 |
| GO:BP | GO:0001649 | osteoblast differentiation | 1 | UFL1 | 179 | 1.0000000 |
| GO:BP | GO:0001568 | blood vessel development | 1 | PML | 537 | 1.0000000 |
| GO:BP | GO:0001503 | ossification | 1 | UFL1 | 317 | 1.0000000 |
| GO:BP | GO:0061458 | reproductive system development | 1 | BAK1 | 217 | 1.0000000 |
| GO:BP | GO:0048514 | blood vessel morphogenesis | 1 | PML | 461 | 1.0000000 |
| GO:BP | GO:0000244 | spliceosomal tri-snRNP complex assembly | 2 | ZNF638,AAR2 | 21 | 1.0000000 |
| GO:BP | GO:0048608 | reproductive structure development | 1 | BAK1 | 214 | 1.0000000 |
| GO:BP | GO:0050670 | regulation of lymphocyte proliferation | 1 | MAD1L1 | 125 | 1.0000000 |
| GO:BP | GO:0000387 | spliceosomal snRNP assembly | 1 | COIL | 47 | 1.0000000 |
| GO:BP | GO:0044282 | small molecule catabolic process | 2 | GNPDA2,PPARD | 270 | 1.0000000 |
| GO:BP | GO:0045291 | mRNA trans splicing, SL addition | 1 | ZNF638 | 7 | 1.0000000 |
| KEGG | KEGG:05168 | Herpes simplex virus 1 infection | 19 | ZNF195,PPP1CA,SRSF8,TBK1,ZNF605,PML,ZFP90,ZNF561,ZNF440,ZNF383,ZNF527,ZFP30,ZNF780A,ZNF230,ZNF226,ZNF432,ZNF480,ZNF548,ZNF324 | 414 | 0.0289451 |
| KEGG | KEGG:04144 | Endocytosis | 13 | ASAP3,AP2A2,VPS37C,ARAP1,PML,CHMP1A,RABEP1,CHMP6,SH3GL1,STAM2,ARFGEF2,RAB7A,ZFYVE16 | 232 | 0.1966195 |
| KEGG | KEGG:05031 | Amphetamine addiction | 3 | HDAC1,PPP3CB,PPP1CA | 49 | 0.2014024 |
| KEGG | KEGG:00900 | Terpenoid backbone biosynthesis | 1 | ICMT | 21 | 0.2014024 |
| KEGG | KEGG:03250 | Viral life cycle - HIV-1 | 5 | RAN,CHMP6,RANBP2,SMARCB1,NELFA | 56 | 0.2014024 |
| KEGG | KEGG:04213 | Longevity regulating pathway - multiple species | 4 | HDAC1,PRKAB1,RPS6KB1,RPTOR | 55 | 0.2014024 |
| KEGG | KEGG:03015 | mRNA surveillance pathway | 5 | CLP1,PPP1CA,PCF11,CASC3,EIF4A3 | 87 | 0.2014024 |
| KEGG | KEGG:04146 | Peroxisome | 1 | PEX14 | 68 | 0.3673096 |
| KEGG | KEGG:04218 | Cellular senescence | 5 | PPP3CB,RAD9A,PPP1CA,CDK4,E2F4 | 145 | 0.3673096 |
| KEGG | KEGG:00565 | Ether lipid metabolism | 3 | PAFAH1B2,PAFAH1B1,GDPD1 | 28 | 0.3673096 |
| KEGG | KEGG:04924 | Renin secretion | 2 | ADORA1,PPP3CB | 50 | 0.3673096 |
| KEGG | KEGG:03013 | Nucleocytoplasmic transport | 5 | IPO13,RAN,CASC3,EIF4A3,RANBP2 | 99 | 0.3754923 |
| KEGG | KEGG:04710 | Circadian rhythm | 2 | CRY1,PRKAB1 | 30 | 0.3754923 |
| KEGG | KEGG:05166 | Human T-cell leukemia virus 1 infection | 5 | PPP3CB,BUB3,KAT5,CDK4,RAN | 180 | 0.3754923 |
| KEGG | KEGG:05212 | Pancreatic cancer | 5 | CDK4,RPS6KB1,RAC3,BAK1,RALGDS | 75 | 0.4828849 |
| KEGG | KEGG:04666 | Fc gamma R-mediated phagocytosis | 1 | ASAP3 | 75 | 0.4828849 |
| KEGG | KEGG:04022 | cGMP-PKG signaling pathway | 3 | ADORA1,PPP3CB,PPP1CA | 133 | 0.4828849 |
| KEGG | KEGG:03060 | Protein export | 2 | SRP68,SPCS1 | 23 | 0.4828849 |
| KEGG | KEGG:00970 | Aminoacyl-tRNA biosynthesis | 3 | FARSA,HARS2,RARS1 | 44 | 0.4828849 |
| KEGG | KEGG:05016 | Huntington disease | 4 | HDAC1,AP2A2,BDNF,POLR2G | 256 | 0.4828849 |
| KEGG | KEGG:04330 | Notch signaling pathway | 1 | HDAC1 | 51 | 0.4828849 |
| KEGG | KEGG:04110 | Cell cycle | 5 | HDAC1,BUB3,CDK4,E2F4,FZR1 | 151 | 0.4828849 |
| KEGG | KEGG:00563 | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis | 1 | PIGC | 25 | 0.4828849 |
| KEGG | KEGG:05034 | Alcoholism | 3 | HDAC1,BDNF,PPP1CA | 117 | 0.4828849 |
| KEGG | KEGG:03020 | RNA polymerase | 3 | POLR2G,POLR1C,POLR1F | 34 | 0.4828849 |
| KEGG | KEGG:00564 | Glycerophospholipid metabolism | 1 | LYPLA2 | 76 | 0.4828849 |
| KEGG | KEGG:04720 | Long-term potentiation | 2 | PPP3CB,PPP1CA | 55 | 0.4828849 |
| KEGG | KEGG:05170 | Human immunodeficiency virus 1 infection | 6 | PPP3CB,TBK1,RPS6KB1,RAC3,MAP2K7,AP1M1 | 165 | 0.4828849 |
| KEGG | KEGG:05220 | Chronic myeloid leukemia | 1 | HDAC1 | 75 | 0.4977706 |
| KEGG | KEGG:04115 | p53 signaling pathway | 2 | EI24,CDK4 | 65 | 0.5110305 |
| KEGG | KEGG:04910 | Insulin signaling pathway | 4 | PPP1CA,PRKAB1,RPS6KB1,RPTOR | 121 | 0.5110305 |
| KEGG | KEGG:00310 | Lysine degradation | 2 | SUV39H2,KMT5A | 59 | 0.5110305 |
| KEGG | KEGG:05132 | Salmonella infection | 1 | PLEKHM2 | 214 | 0.5114731 |
| KEGG | KEGG:04921 | Oxytocin signaling pathway | 3 | PPP3CB,PPP1CA,PRKAB1 | 115 | 0.5229332 |
| KEGG | KEGG:04211 | Longevity regulating pathway | 3 | PRKAB1,RPS6KB1,RPTOR | 78 | 0.5229332 |
| KEGG | KEGG:03450 | Non-homologous end-joining | 1 | LIG4 | 12 | 0.5229332 |
| KEGG | KEGG:04120 | Ubiquitin mediated proteolysis | 4 | HERC4,PML,FZR1,PIAS4 | 134 | 0.5229332 |
| KEGG | KEGG:04024 | cAMP signaling pathway | 3 | ADORA1,BDNF,PPP1CA | 151 | 0.5229332 |
| KEGG | KEGG:05418 | Fluid shear stress and atherosclerosis | 4 | GSTP1,RAC3,PIAS4,MAP2K7 | 114 | 0.5229332 |
| KEGG | KEGG:05210 | Colorectal cancer | 4 | RPS6KB1,RAC3,BAK1,RALGDS | 84 | 0.5261649 |
| KEGG | KEGG:04922 | Glucagon signaling pathway | 2 | PPP3CB,PRKAB1 | 84 | 0.5261649 |
| KEGG | KEGG:04923 | Regulation of lipolysis in adipocytes | 1 | ADORA1 | 41 | 0.5261649 |
| KEGG | KEGG:04931 | Insulin resistance | 3 | PPP1CA,PRKAB1,RPS6KB1 | 95 | 0.5261649 |
| KEGG | KEGG:04660 | T cell receptor signaling pathway | 3 | PPP3CB,CDK4,MAP2K7 | 70 | 0.5261649 |
| KEGG | KEGG:04613 | Neutrophil extracellular trap formation | 1 | HDAC1 | 105 | 0.5261649 |
| KEGG | KEGG:04961 | Endocrine and other factor-regulated calcium reabsorption | 1 | AP2A2 | 41 | 0.5261649 |
| KEGG | KEGG:05030 | Cocaine addiction | 1 | BDNF | 35 | 0.5261649 |
| KEGG | KEGG:00770 | Pantothenate and CoA biosynthesis | 1 | PPCDC | 15 | 0.5261649 |
| KEGG | KEGG:05167 | Kaposi sarcoma-associated herpesvirus infection | 3 | PPP3CB,CDK4,TBK1 | 145 | 0.5261649 |
| KEGG | KEGG:05164 | Influenza A | 3 | CDK4,TBK1,PML | 103 | 0.5261649 |
| KEGG | KEGG:05163 | Human cytomegalovirus infection | 5 | PPP3CB,CDK4,TBK1,RPS6KB1,RAC3 | 176 | 0.5261649 |
| KEGG | KEGG:00983 | Drug metabolism - other enzymes | 2 | GSTP1,CES2 | 44 | 0.5261649 |
| KEGG | KEGG:04140 | Autophagy - animal | 5 | TBK1,RPS6KB1,RPTOR,RAB1A,RAB7A | 133 | 0.5261649 |
| KEGG | KEGG:04114 | Oocyte meiosis | 2 | PPP3CB,PPP1CA | 108 | 0.5261649 |
| KEGG | KEGG:03008 | Ribosome biogenesis in eukaryotes | 3 | RAN,EFL1,UTP6 | 75 | 0.5261649 |
| KEGG | KEGG:05202 | Transcriptional misregulation in cancer | 1 | HDAC1 | 128 | 0.5261649 |
| KEGG | KEGG:05169 | Epstein-Barr virus infection | 3 | HDAC1,CDK4,TBK1 | 152 | 0.5261649 |
| KEGG | KEGG:04215 | Apoptosis - multiple species | 2 | DIABLO,BAK1 | 30 | 0.5261649 |
| KEGG | KEGG:05203 | Viral carcinogenesis | 1 | HDAC1 | 165 | 0.5261649 |
| KEGG | KEGG:05225 | Hepatocellular carcinoma | 6 | GSTP1,CDK4,RPS6KB1,SMARCB1,ACTL6A,BAK1 | 145 | 0.5261649 |
| KEGG | KEGG:04152 | AMPK signaling pathway | 3 | PRKAB1,RPS6KB1,RPTOR | 103 | 0.5261649 |
| KEGG | KEGG:04370 | VEGF signaling pathway | 2 | PPP3CB,RAC3 | 49 | 0.5261649 |
| KEGG | KEGG:05410 | Hypertrophic cardiomyopathy | 2 | LMNA,PRKAB1 | 73 | 0.5261649 |
| KEGG | KEGG:05412 | Arrhythmogenic right ventricular cardiomyopathy | 1 | LMNA | 63 | 0.5261649 |
| KEGG | KEGG:00562 | Inositol phosphate metabolism | 3 | IPMK,INPP1,SACM1L | 66 | 0.5261649 |
| KEGG | KEGG:04145 | Phagosome | 1 | STX12 | 99 | 0.5261649 |
| KEGG | KEGG:05414 | Dilated cardiomyopathy | 1 | LMNA | 78 | 0.5261649 |
| KEGG | KEGG:04728 | Dopaminergic synapse | 2 | PPP3CB,PPP1CA | 102 | 0.5261649 |
| KEGG | KEGG:04919 | Thyroid hormone signaling pathway | 1 | HDAC1 | 112 | 0.5261649 |
| KEGG | KEGG:05221 | Acute myeloid leukemia | 3 | PML,RPS6KB1,PPARD | 56 | 0.5261649 |
| KEGG | KEGG:05032 | Morphine addiction | 1 | ADORA1 | 56 | 0.5264123 |
| KEGG | KEGG:04071 | Sphingolipid signaling pathway | 3 | ADORA1,RAC3,CERS4 | 107 | 0.5593040 |
| KEGG | KEGG:04664 | Fc epsilon RI signaling pathway | 2 | RAC3,MAP2K7 | 46 | 0.5715765 |
| KEGG | KEGG:05162 | Measles | 2 | CDK4,TBK1 | 97 | 0.6019181 |
| KEGG | KEGG:05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 1 | PPP3CB | 69 | 0.6019181 |
| KEGG | KEGG:04210 | Apoptosis | 1 | LMNA | 118 | 0.6019181 |
| KEGG | KEGG:04070 | Phosphatidylinositol signaling system | 1 | IPMK | 91 | 0.6019181 |
| KEGG | KEGG:04721 | Synaptic vesicle cycle | 1 | AP2A2 | 51 | 0.6019181 |
| KEGG | KEGG:05219 | Bladder cancer | 1 | CDK4 | 37 | 0.6019181 |
| KEGG | KEGG:00480 | Glutathione metabolism | 1 | GSTP1 | 44 | 0.6019181 |
| KEGG | KEGG:04662 | B cell receptor signaling pathway | 1 | PPP3CB | 56 | 0.6019181 |
| KEGG | KEGG:04658 | Th1 and Th2 cell differentiation | 1 | PPP3CB | 53 | 0.6019181 |
| KEGG | KEGG:05135 | Yersinia infection | 3 | TBK1,RAC3,MAP2K7 | 112 | 0.6019181 |
| KEGG | KEGG:03010 | Ribosome | 1 | MRPL9 | 127 | 0.6019181 |
| KEGG | KEGG:04150 | mTOR signaling pathway | 3 | WDR24,RPS6KB1,RPTOR | 135 | 0.6056535 |
| KEGG | KEGG:01524 | Platinum drug resistance | 1 | GSTP1 | 65 | 0.6056535 |
| KEGG | KEGG:05204 | Chemical carcinogenesis - DNA adducts | 1 | GSTP1 | 23 | 0.6056535 |
| KEGG | KEGG:04625 | C-type lectin receptor signaling pathway | 1 | PPP3CB | 76 | 0.6056535 |
| KEGG | KEGG:00982 | Drug metabolism - cytochrome P450 | 1 | GSTP1 | 21 | 0.6056535 |
| KEGG | KEGG:04659 | Th17 cell differentiation | 1 | PPP3CB | 64 | 0.6056535 |
| KEGG | KEGG:01522 | Endocrine resistance | 2 | CDK4,RPS6KB1 | 85 | 0.6056535 |
| KEGG | KEGG:05206 | MicroRNAs in cancer | 1 | HDAC1 | 149 | 0.6056535 |
| KEGG | KEGG:04350 | TGF-beta signaling pathway | 2 | E2F4,RPS6KB1 | 84 | 0.6056535 |
| KEGG | KEGG:05165 | Human papillomavirus infection | 1 | HDAC1 | 272 | 0.6056535 |
| KEGG | KEGG:03022 | Basal transcription factors | 2 | GTF2F2,GTF2IRD1 | 40 | 0.6056535 |
| KEGG | KEGG:04936 | Alcoholic liver disease | 3 | TBK1,PRKAB1,MAP2K7 | 97 | 0.6056535 |
| KEGG | KEGG:03050 | Proteasome | 2 | PSMD14,PSMB1 | 42 | 0.6056535 |
| KEGG | KEGG:05160 | Hepatitis C | 2 | CDK4,TBK1 | 114 | 0.6056535 |
| KEGG | KEGG:04012 | ErbB signaling pathway | 2 | RPS6KB1,MAP2K7 | 78 | 0.6056535 |
| KEGG | KEGG:04724 | Glutamatergic synapse | 1 | PPP3CB | 74 | 0.6056535 |
| KEGG | KEGG:04014 | Ras signaling pathway | 3 | BDNF,TBK1,RALGAPA1 | 171 | 0.6056535 |
| KEGG | KEGG:00980 | Metabolism of xenobiotics by cytochrome P450 | 1 | GSTP1 | 26 | 0.6134512 |
| KEGG | KEGG:04136 | Autophagy - other | 1 | RPTOR | 31 | 0.6159664 |
| KEGG | KEGG:04380 | Osteoclast differentiation | 1 | PPP3CB | 87 | 0.6233804 |
| KEGG | KEGG:04650 | Natural killer cell mediated cytotoxicity | 1 | PPP3CB | 63 | 0.6233804 |
| KEGG | KEGG:05231 | Choline metabolism in cancer | 2 | RPS6KB1,RAC3 | 84 | 0.6236130 |
| KEGG | KEGG:03420 | Nucleotide excision repair | 1 | ERCC4 | 43 | 0.6276084 |
| KEGG | KEGG:04010 | MAPK signaling pathway | 2 | PPP3CB,BDNF | 240 | 0.6369039 |
| KEGG | KEGG:04530 | Tight junction | 2 | CDK4,PRKAB1 | 137 | 0.6369039 |
| KEGG | KEGG:04310 | Wnt signaling pathway | 5 | PPP3CB,RAC3,CTBP1,PPARD,PPP3CC | 139 | 0.6421610 |
| KEGG | KEGG:03460 | Fanconi anemia pathway | 1 | ERCC4 | 49 | 0.6421610 |
| KEGG | KEGG:05215 | Prostate cancer | 1 | GSTP1 | 86 | 0.6421610 |
| KEGG | KEGG:04137 | Mitophagy - animal | 1 | TBK1 | 70 | 0.6421610 |
| KEGG | KEGG:05218 | Melanoma | 1 | CDK4 | 58 | 0.6421610 |
| KEGG | KEGG:04750 | Inflammatory mediator regulation of TRP channels | 1 | PPP1CA | 72 | 0.6421610 |
| KEGG | KEGG:04623 | Cytosolic DNA-sensing pathway | 1 | TBK1 | 41 | 0.6421610 |
| KEGG | KEGG:04722 | Neurotrophin signaling pathway | 1 | BDNF | 110 | 0.6421610 |
| KEGG | KEGG:05214 | Glioma | 1 | CDK4 | 67 | 0.6421610 |
| KEGG | KEGG:05223 | Non-small cell lung cancer | 1 | CDK4 | 67 | 0.6421610 |
| KEGG | KEGG:04620 | Toll-like receptor signaling pathway | 2 | TBK1,MAP2K7 | 60 | 0.6421610 |
| KEGG | KEGG:04622 | RIG-I-like receptor signaling pathway | 1 | TBK1 | 48 | 0.6421610 |
| KEGG | KEGG:04920 | Adipocytokine signaling pathway | 1 | PRKAB1 | 51 | 0.6451022 |
| KEGG | KEGG:04914 | Progesterone-mediated oocyte maturation | 3 | FZR1,CPEB4,MAD1L1 | 86 | 0.6451022 |
| KEGG | KEGG:05200 | Pathways in cancer | 1 | HDAC1 | 409 | 0.6531345 |
| KEGG | KEGG:05417 | Lipid and atherosclerosis | 2 | PPP3CB,TBK1 | 153 | 0.6531345 |
| KEGG | KEGG:04913 | Ovarian steroidogenesis | 1 | HSD17B1 | 28 | 0.6531345 |
| KEGG | KEGG:03040 | Spliceosome | 4 | SRSF8,EIF4A3,DHX16,SRSF3 | 132 | 0.6531345 |
| KEGG | KEGG:05152 | Tuberculosis | 1 | PPP3CB | 106 | 0.6620791 |
| KEGG | KEGG:04714 | Thermogenesis | 6 | PRKAB1,RPS6KB1,RPTOR,SMARCB1,ACTL6A,COX19 | 195 | 0.6620791 |
| KEGG | KEGG:04392 | Hippo signaling pathway - multiple species | 1 | MOB1B | 26 | 0.6671480 |
| KEGG | KEGG:04360 | Axon guidance | 1 | PPP3CB | 162 | 0.6671480 |
| KEGG | KEGG:04340 | Hedgehog signaling pathway | 1 | SPOP | 50 | 0.6765000 |
| KEGG | KEGG:04657 | IL-17 signaling pathway | 1 | TBK1 | 56 | 0.6765000 |
| KEGG | KEGG:05222 | Small cell lung cancer | 1 | CDK4 | 87 | 0.6765000 |
| KEGG | KEGG:04611 | Platelet activation | 1 | PPP1CA | 89 | 0.6783915 |
| KEGG | KEGG:04217 | Necroptosis | 3 | CHMP1A,CHMP6,STAT4 | 108 | 0.6783915 |
| KEGG | KEGG:04371 | Apelin signaling pathway | 2 | PRKAB1,RPS6KB1 | 106 | 0.6783915 |
| KEGG | KEGG:05416 | Viral myocarditis | 1 | RAC3 | 40 | 0.6783915 |
| KEGG | KEGG:04141 | Protein processing in endoplasmic reticulum | 4 | MAP2K7,NSFL1C,DNAJC5,BAK1 | 161 | 0.6783915 |
| KEGG | KEGG:00140 | Steroid hormone biosynthesis | 1 | HSD17B1 | 19 | 0.6783915 |
| KEGG | KEGG:04270 | Vascular smooth muscle contraction | 1 | PPP1CA | 94 | 0.6783915 |
| KEGG | KEGG:04933 | AGE-RAGE signaling pathway in diabetic complications | 1 | CDK4 | 91 | 0.6783915 |
| KEGG | KEGG:05017 | Spinocerebellar ataxia | 1 | KAT5 | 124 | 0.6783915 |
| KEGG | KEGG:00600 | Sphingolipid metabolism | 1 | CERS4 | 44 | 0.6783915 |
| KEGG | KEGG:05161 | Hepatitis B | 3 | TBK1,MAP2K7,STAT4 | 135 | 0.6783915 |
| KEGG | KEGG:04630 | JAK-STAT signaling pathway | 3 | PIAS4,STAM2,STAT4 | 88 | 0.6806920 |
| KEGG | KEGG:05224 | Breast cancer | 2 | CDK4,RPS6KB1 | 117 | 0.6811029 |
| KEGG | KEGG:04020 | Calcium signaling pathway | 1 | PPP3CB | 157 | 0.7187221 |
| KEGG | KEGG:04261 | Adrenergic signaling in cardiomyocytes | 1 | PPP1CA | 128 | 0.7207243 |
| KEGG | KEGG:04390 | Hippo signaling pathway | 1 | PPP1CA | 135 | 0.7250995 |
| KEGG | KEGG:05216 | Thyroid cancer | 1 | BAK1 | 35 | 0.7296060 |
| KEGG | KEGG:05131 | Shigellosis | 3 | TBK1,RPS6KB1,RPTOR | 210 | 0.7403762 |
| KEGG | KEGG:04520 | Adherens junction | 1 | RAC3 | 67 | 0.7416960 |
| KEGG | KEGG:05020 | Prion disease | 1 | PPP3CB | 220 | 0.7416960 |
| KEGG | KEGG:05134 | Legionellosis | 1 | RAB1A | 39 | 0.7416960 |
| KEGG | KEGG:04080 | Neuroactive ligand-receptor interaction | 1 | ADORA1 | 108 | 0.7416960 |
| KEGG | KEGG:05022 | Pathways of neurodegeneration - multiple diseases | 2 | PPP3CB,BDNF | 386 | 0.7499097 |
| KEGG | KEGG:01521 | EGFR tyrosine kinase inhibitor resistance | 1 | RPS6KB1 | 74 | 0.7514838 |
| KEGG | KEGG:04151 | PI3K-Akt signaling pathway | 4 | BDNF,CDK4,RPS6KB1,RPTOR | 254 | 0.7540450 |
| KEGG | KEGG:00000 | KEGG root term | 2 | ICMT,PEX14 | 5553 | 0.7540450 |
| KEGG | KEGG:04934 | Cushing syndrome | 1 | CDK4 | 121 | 0.7540450 |
| KEGG | KEGG:04068 | FoxO signaling pathway | 1 | PRKAB1 | 110 | 0.7540450 |
| KEGG | KEGG:05014 | Amyotrophic lateral sclerosis | 8 | PPP3CB,TBK1,RAB1A,RANBP2,PSMD14,SRSF3,PSMB1,PPP3CC | 303 | 0.7540450 |
| KEGG | KEGG:01240 | Biosynthesis of cofactors | 2 | PPCDC,RDH13 | 115 | 0.7540450 |
| KEGG | KEGG:00520 | Amino sugar and nucleotide sugar metabolism | 1 | GNPDA2 | 46 | 0.7540450 |
| KEGG | KEGG:04510 | Focal adhesion | 1 | PPP1CA | 177 | 0.7540450 |
| KEGG | KEGG:00830 | Retinol metabolism | 1 | RDH13 | 16 | 0.7540450 |
| KEGG | KEGG:05321 | Inflammatory bowel disease | 1 | STAT4 | 22 | 0.7540450 |
| KEGG | KEGG:05415 | Diabetic cardiomyopathy | 1 | PPP1CA | 169 | 0.7540450 |
| KEGG | KEGG:05205 | Proteoglycans in cancer | 1 | PPP1CA | 170 | 0.7540450 |
| KEGG | KEGG:04932 | Non-alcoholic fatty liver disease | 1 | PRKAB1 | 131 | 0.7858286 |
| KEGG | KEGG:04810 | Regulation of actin cytoskeleton | 1 | PPP1CA | 179 | 0.7885689 |
| KEGG | KEGG:05010 | Alzheimer disease | 1 | PPP3CB | 316 | 0.7988949 |
| KEGG | KEGG:04912 | GnRH signaling pathway | 1 | MAP2K7 | 76 | 0.7988949 |
| KEGG | KEGG:05213 | Endometrial cancer | 1 | BAK1 | 57 | 0.7988949 |
| KEGG | KEGG:05100 | Bacterial invasion of epithelial cells | 1 | SEPTIN2 | 74 | 0.7988949 |
| KEGG | KEGG:04621 | NOD-like receptor signaling pathway | 1 | TBK1 | 117 | 0.7988949 |
| KEGG | KEGG:00230 | Purine metabolism | 2 | DGUOK,PAICS | 97 | 0.7988949 |
| KEGG | KEGG:04066 | HIF-1 signaling pathway | 1 | RPS6KB1 | 89 | 0.7988949 |
| KEGG | KEGG:04064 | NF-kappa B signaling pathway | 1 | PIAS4 | 70 | 0.8003798 |
| KEGG | KEGG:01232 | Nucleotide metabolism | 1 | DGUOK | 69 | 0.8005728 |
| KEGG | KEGG:05217 | Basal cell carcinoma | 1 | BAK1 | 49 | 0.8156826 |
| KEGG | KEGG:04668 | TNF signaling pathway | 1 | MAP2K7 | 87 | 0.8301102 |
| KEGG | KEGG:05171 | Coronavirus disease - COVID-19 | 1 | TBK1 | 161 | 0.8494962 |
| KEGG | KEGG:03320 | PPAR signaling pathway | 1 | PPARD | 50 | 0.8631254 |
| KEGG | KEGG:04926 | Relaxin signaling pathway | 1 | MAP2K7 | 104 | 0.8631254 |
| KEGG | KEGG:05226 | Gastric cancer | 1 | RPS6KB1 | 117 | 0.8690913 |
| KEGG | KEGG:04142 | Lysosome | 1 | AP1M1 | 118 | 0.8721967 |
| KEGG | KEGG:01100 | Metabolic pathways | 3 | PIGC,SUV39H2,IPMK | 1147 | 0.8775155 |
| KEGG | KEGG:05146 | Amoebiasis | 1 | RAB7A | 64 | 0.8931225 |
| KEGG | KEGG:04062 | Chemokine signaling pathway | 1 | RAC3 | 113 | 0.9362021 |
| KEGG | KEGG:05207 | Chemical carcinogenesis - receptor activation | 1 | RPS6KB1 | 142 | 0.9428573 |
| KEGG | KEGG:04015 | Rap1 signaling pathway | 1 | RAC3 | 164 | 0.9431059 |
| KEGG | KEGG:05012 | Parkinson disease | 2 | SLC39A3,PSMD14 | 226 | 0.9431059 |
| KEGG | KEGG:05130 | Pathogenic Escherichia coli infection | 2 | RAB1A,BAK1 | 150 | 0.9431059 |
| KEGG | KEGG:04550 | Signaling pathways regulating pluripotency of stem cells | 1 | SMARCAD1 | 104 | 0.9494064 |
| KEGG | KEGG:05208 | Chemical carcinogenesis - reactive oxygen species | 1 | MAP2K7 | 186 | 0.9494064 |
| KEGG | KEGG:04072 | Phospholipase D signaling pathway | 1 | RALGDS | 110 | 0.9773988 |
looking at the enriched HSV-1 genes in my data:
# FC_mine %>%
# dplyr::filter(time=="3_hours") %>%
# dplyr::filter(ENTREZID %in% KEGG_05168$GeneID)B set
# SETB_resgenes <- gost(query = intersect_genes$ENTREZID,
# organism = "hsapiens",
# significant = FALSE,
# ordered_query = TRUE,
# domain_scope = "custom",
# measure_underrepresentation = FALSE,
# evcodes = FALSE,
# user_threshold = 0.05,
# correction_method = c("fdr"),
# custom_bg = EPI508_list$ENTREZID,
# sources=c("KEGG"))
# saveRDS(SETB_resgenes,"data/DEG-GO/SETB_resgenes.RDS")
# SETB_resgenes <- readRDS("data/DEG-GO/SETB_resgenes.RDS")
#
# Set_B_genes <- gostplot(SETB_resgenes, capped = FALSE, interactive = TRUE)
# Set_B_genes
#
# setB_table <- SETB_resgenes$result %>%
# dplyr::select(c(source, term_id,
# term_name,intersection_size,
# term_size, p_value))# %>%
#
# # list_intersect_path <- KEGG_05168 %>%
# # filter(Symbol%in% intersect_genes$SYMBOL)
#
# setB_table%>%
# kable(., caption = "No enrichment with this small background of KEGG pathway") %>%
# kable_paper("striped", full_width = FALSE) %>%
# kable_styling(
# full_width = FALSE,
# position = "left",
# bootstrap_options = c("striped", "hover")
# ) %>%
# scroll_box(width = "100%", height = "400px")Link to other pages here:
GO analysis on after_comments data here
sessionInfo()R version 4.3.1 (2023-06-16 ucrt)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19045)
Matrix products: default
locale:
[1] LC_COLLATE=English_United States.utf8
[2] LC_CTYPE=English_United States.utf8
[3] LC_MONETARY=English_United States.utf8
[4] LC_NUMERIC=C
[5] LC_TIME=English_United States.utf8
time zone: America/Chicago
tzcode source: internal
attached base packages:
[1] stats4 grid stats graphics grDevices utils datasets
[8] methods base
other attached packages:
[1] org.Hs.eg.db_3.17.0 AnnotationDbi_1.62.2 IRanges_2.34.1
[4] S4Vectors_0.38.2 Biobase_2.60.0 BiocGenerics_0.46.0
[7] gprofiler2_0.2.2 qvalue_2.32.0 RColorBrewer_1.1-3
[10] edgeR_3.42.4 limma_3.56.2 biomaRt_2.56.1
[13] ggVennDiagram_1.2.3 ComplexHeatmap_2.16.0 broom_1.0.5
[16] kableExtra_1.3.4 sjmisc_2.8.9 scales_1.2.1
[19] ggpubr_0.6.0 cowplot_1.1.1 ggsignif_0.6.4
[22] lubridate_1.9.3 forcats_1.0.0 stringr_1.5.0
[25] dplyr_1.1.3 purrr_1.0.2 readr_2.1.4
[28] tidyr_1.3.0 tibble_3.2.1 ggplot2_3.4.4
[31] tidyverse_2.0.0 workflowr_1.7.1
loaded via a namespace (and not attached):
[1] splines_4.3.1 later_1.3.1 bitops_1.0-7
[4] filelock_1.0.2 XML_3.99-0.15 lifecycle_1.0.4
[7] sf_1.0-14 rstatix_0.7.2 doParallel_1.0.17
[10] rprojroot_2.0.4 processx_3.8.2 lattice_0.22-5
[13] vroom_1.6.4 insight_0.19.6 crosstalk_1.2.0
[16] backports_1.4.1 magrittr_2.0.3 plotly_4.10.3
[19] sass_0.4.7 rmarkdown_2.25 jquerylib_0.1.4
[22] yaml_2.3.7 httpuv_1.6.12 DBI_1.1.3
[25] abind_1.4-5 zlibbioc_1.46.0 rvest_1.0.3
[28] RCurl_1.98-1.13 yulab.utils_0.1.0 rappdirs_0.3.3
[31] git2r_0.32.0 circlize_0.4.15 GenomeInfoDbData_1.2.10
[34] units_0.8-4 svglite_2.1.2 codetools_0.2-19
[37] xml2_1.3.5 tidyselect_1.2.0 shape_1.4.6
[40] farver_2.1.1 matrixStats_1.1.0 BiocFileCache_2.8.0
[43] webshot_0.5.5 jsonlite_1.8.7 GetoptLong_1.0.5
[46] e1071_1.7-13 ellipsis_0.3.2 iterators_1.0.14
[49] systemfonts_1.0.5 foreach_1.5.2 tools_4.3.1
[52] progress_1.2.2 Rcpp_1.0.11 glue_1.6.2
[55] xfun_0.41 mgcv_1.9-0 GenomeInfoDb_1.36.4
[58] withr_2.5.2 fastmap_1.1.1 fansi_1.0.5
[61] callr_3.7.3 digest_0.6.33 mime_0.12
[64] timechange_0.2.0 R6_2.5.1 colorspace_2.1-0
[67] RSQLite_2.3.3 utf8_1.2.4 generics_0.1.3
[70] data.table_1.14.8 class_7.3-22 prettyunits_1.2.0
[73] httr_1.4.7 htmlwidgets_1.6.2 whisker_0.4.1
[76] pkgconfig_2.0.3 gtable_0.3.4 blob_1.2.4
[79] XVector_0.40.0 htmltools_0.5.7 carData_3.0-5
[82] clue_0.3-65 png_0.1-8 knitr_1.45
[85] rstudioapi_0.15.0 tzdb_0.4.0 reshape2_1.4.4
[88] rjson_0.2.21 nlme_3.1-163 curl_5.1.0
[91] proxy_0.4-27 cachem_1.0.8 GlobalOptions_0.1.2
[94] sjlabelled_1.2.0 RVenn_1.1.0 KernSmooth_2.23-22
[97] parallel_4.3.1 pillar_1.9.0 vctrs_0.6.4
[100] promises_1.2.1 car_3.1-2 dbplyr_2.3.4
[103] xtable_1.8-4 cluster_2.1.4 evaluate_0.23
[106] magick_2.8.1 cli_3.6.1 locfit_1.5-9.8
[109] compiler_4.3.1 rlang_1.1.2 crayon_1.5.2
[112] labeling_0.4.3 classInt_0.4-10 ps_1.7.5
[115] plyr_1.8.9 getPass_0.2-2 fs_1.6.3
[118] stringi_1.7.12 viridisLite_0.4.2 munsell_0.5.0
[121] Biostrings_2.68.1 lazyeval_0.2.2 Matrix_1.6-2
[124] hms_1.1.3 bit64_4.0.5 shiny_1.7.5.1
[127] KEGGREST_1.40.1 highr_0.10 memoise_2.0.1
[130] bslib_0.5.1 bit_4.0.5